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| 1 | Portal vein thrombosis:Insight into physiopathology,diagnosis,and treatment显示文摘Portal vein thrombosis (PVT) is a relatively common complication in patients with liver cirrhosis, but might also occur in absence of an overt liver disease. Several causes, either local or systemic, might play an important role in PVT pathogenesis. Frequently, more than one risk factor could be identified; however, occasionally no single factor is discernable. Clinical examination, laboratory investigations, and imaging are helpful to provide a quick diagnosis, as prompt treatment might greatly affect a patient's outcome. In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures. Finally, we analyze the implications of PVT in the setting of liver transplantation and its possible influence on patients' future prognoses. | Francesca R Ponziani Maria A Zocco Chiara Campanale Emanuele Rinninella Annalisa Tortora Luca Di Maurizio Giuseppe Bombardieri Raimondo De Cristofaro Anna M De Gaetano Raffaele Landolfi Antonio Gasbarrini | 2010 | World Journal of Gastroenterology2010，16，2： | 75 |
| 2 | Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis显示文摘AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis.METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine,butyrate,or saline.Enemas were administered twice a week in the excluded segment of the colon from 4 to 12 wk after the surgical procedure.Follow-up colonoscopy was performed every 4 wk for 12 wk.The effect of treatment was evaluated using video-endoscopic and histologic scores and measuring interleukin-1β,tumor necrosis factor-alpha,and transforming growth factor beta production in organ cultures by enzyme linked immunosorbent assay.RESULTS:Colonoscopies of the diverted segment showed mucosa with hyperemia,increased number of vessels,bleeding and mucus discharge.Treatment with either glutamine or butyrate induced significant reductions in both colonoscopic(P < 0.02) and histological scores(P < 0.01) and restored the densities of collagen fibers in tissue(P = 0.015;P = 0.001),the number of goblet cells(P = 0.021;P = 0.029),and the rate of apoptosis within the epithelium(P = 0.043;P = 0.011) to normal values.The high levels of cytokines in colon explants from rats with diversion colitis significantly decreased to normal values after treatment with butyrate or glutamine.CONCLUSION:The improvement of experimental diversion colitis following glutamine or butyrate enemas highlights the importance of specific luminal nutrients in the homeostasis of the colonic mucosa and supports their utilization for the treatment of human diversion colitis. | Rodrigo Goulart Pacheco Christiano Costa Esposito Lucas CM Müller Morgana TL Castelo-Branco Leonardo Pereira Quintella Vera Lucia A Chagas Heitor Siffert P de Souza Alberto Schanaider | 2012 | World Journal of Gastroenterology2012，18，32： | 9 |
| 3 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘 | Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc | 2013 | Gut2013，，12： | 2 |
| 4 | 术前检测患者血液中总蛋白、白蛋白与白细胞介素-1受体拮抗剂作为切口疝修补术后是否出现血清肿的预测指标显示文摘患者切口疝修补术后出现血清肿是非常常见的,约占20%~30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,甚至是手术治疗都是必要的。 | Klink CD Binnebosel M Lucas AH Schachtrupp A Grommes J Conze J Klinge U Neumann U Junge K 宗振(译) 陈双(校) | 2012 | 中华疝和腹壁外科杂志(电子版)2012，6，2： | 2 |
| 5 | Enhanced vibration performance of ultrasonic block horns显示文摘 | Cardoni A Lucas M | 2002 | Ultrasonics2002，40，： | 1 |
| 6 | Transformation of maltose into prebiotic isomahooligosaccharides by a novel &-glucosidase from Xantophyllomyces dendrorhous 显示文摘 | Luca F A Dolores M Aranzazu G | 2007 | Process Biochemistry2007，42，： | 1 |
| 7 | Candidemia: species involved, virulence factors and antimycotic susceptibility显示文摘 | De Luca C Guglilminetti M Ferrario A | 2012 | New Microbiol2012，35，4： | 1 |
| 8 | Enhanced vibration performance of ultrasonic block horns显示文摘 | Cardoni A Lucas M | 2002 | Ultrasonics2002，40，18： | 1 |
| 9 | Vinyl sulfonate co-polymers for high-temperature filtration control of wa- ter-base muds显示文摘 | Perricone A C Enright D P Lucas J M | 1986 | SPE Drilling Engineering1986，1，5： | 1 |
| 10 | Regional Clusters in AGlobal Industry : ICT Clusters in Canada 显示文摘 | Lucas M Sands A Wolfe D A | 2009 | EuropeanPlanning Studies2009，17，2： | 1 |
| 11 | HIV-1 tat elongates the G1 phase and indirectly promotes HIV-1 gene expression in cells of glial origin显示文摘 | Kundu M Sharma S De Luca A | 1998 | J Biol Chem1998，273，： | 1 |
| 12 | Spreadsheet Analysis and Design显示文摘 | Ronen B Palley M A Lucas H C J R | 1989 | Communications of the ACM1989，32，1： | 1 |
| 13 | WMR control via dynamic feedback linearization design, implementation and experimental validation显示文摘 | ORIOLO G DE LUCA A VENDITTELLI M | 2002 | IEEE Trans on Control Systems Technology2002，10，6： | 1 |
| 14 | Implementation of emotional controller for Interior permanent-magnet synchronous motor drive 显示文摘 | RAHMAN M A MILASI R M LUCAS C | 2008 | IEEE Transactions on Industry Applications2008，44，5： | 1 |
| 15 | Icdar2003 robust reading competitions 显示文摘 | Lucas S M Panaretos A Sosa L | 2003 | Pattern Recognition2003，36，： | 1 |
| 16 | Redesign of ultrasonic block horns for improved vibration performance 显示文摘 | Lucas M Smith A C | 1997 | Journal of Vibration and Acoustics1997，119，： | 1 |
| 17 | Motion control of omni-directional three-wheel robots by brain-emotional-learning- based Intelligent controller 显示文摘 | SHARBAFI M A LUCAS C DANESHVAR R | 2010 | IEEE Transactions on Systems Man and cybernetics2010，40，6： | 1 |
| 18 | Zoledronic acid blocks the interaction between mesenchymal stem cells and breast cancer cells: implications for adjuvant therapy of breast cancer显示文摘 | GaJIo M De Luca A Lamura L | 2012 | Ann Oncol2012，23，3： | 1 |
| 19 | The taxonomic status of Macrophoma flaccida and Macrophoma reniformis and their relationship to Botryosphaeria dothidea 显示文摘 | Phillips A J L Lucas M T | 1997 | Sydowia1997，49，2： | 1 |
| 20 | In Vitro Testing of a Pulsatile Delivery System and Its in Vivo Application for Immunization Against Tetanus Toxoid显示文摘 | CARDAMONE M LOFTHOUSE S A LUCAS J C | 1997 | J Controlled Release1997，47，3： | 1 |
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