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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009,7,4: | 3 |
| 3 | Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats显示文摘AIM To evaluate the sex-specific effects of a hydroalcoholic extract from Eugenia punicifolia(HEEP) leaves on gastric ulcer healing.METHODS In this rat study involving males, intact(cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid. A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Body weight was monitored throughout the treatment period. At the end of treatment, the rats were euthanized and the following in vivo and in vitro investigations were performed: macroscopic examination of the lesion area and organ weights, biochemical analysis, zymography, and evaluation of protein expression levels. Additionally, the concentration-dependent effect of HEEP was evaluated in terms of subacute toxicity and cytotoxicity.RESULTS Compared to the vehicle, HEEP demonstrated a great healing capacity by substantially reducing the ulcerative lesion area in males(52.44%), intact females(85.22%), and ovariectomized females(65.47%), confirming that HEEP accelerates the healing of acetic acidinduced gastric lesions and suggesting that this effect is modulated by female sex hormones. The antiulcer effect of HEEP was mediated by prostaglandin E2 only in male rats. Overall, the beneficial effect of HEEP was the highest in intact females. Notably, HEEP promoted the expression of vascular endothelial growth factor(intact vs ovariectomized females) and decreased the expression of Caspase-8 and Bcl-2(intact female vs male or ovariectomized female). Additionally, HEEP enhanced fibroblast proliferation and migration into a wounded area in vitro, confirming its healing effect. Finally, no sign of subacute toxicity or cytotoxicity of HEEP was observed.CONCLUSION In gastric ulcers, HEEP-induced healing(modulated by female sex hormones; in males, mediated by prostaglandin) involves extracellular matrix remodeling, with gastric mucosa cell proliferation and migration. | Larissa Lucena Périco Vinícius Peixoto Rodrigues Rie Ohara Gabriela Bueno Vania Vasti Alfieri Nunes Raquel Cássia dos Santos Ana Carolina Lima Camargo Luis Antuio Justulin Joior Sérgio Faloni de Andrade Viviane Miranda Bispo Steimbach Luísa Mota da Silva Lúcia Regina Machado da Rocha Wagner Vilegas Catarina dos Santos Clélia Akiko Hiruma-Lima | 2018 | World Journal of Gastroenterology2018,24,38: | 3 |
| 4 | Influence of processing conditions on the luminescence of YVO4: Eu3 + nanoparticles 显示文摘 | ZHANG H P LU M K XIU Z L | 2006 | Mater Sci Eng: B2006,130,: | 1 |
| 5 | Thermal evolution of the Archaean basement rocks from the eastern part of the North China Craton and its International Geology Review, bearing on tectonic setting 显示文摘 | Zhao G C Wilde S A Cawood P A Lu L Z | 1998 | 40: 706-7211998,40,: | 1 |
| 6 | Thermal stability of recorded information at high densities显示文摘 | Charap S H Lu P L He Y J | 1997 | IEEE Trans Magn1997,33,1: | 1 |
| 7 | Glucose-insulin-potassium preserves systolic and diastolic function in ischemia and reperfusion in pigs 显示文摘 | Zhu P Lu L Xu Y | 2000 | Am J Physiol Heart Circ Physiol2000,278,2: | 1 |
| 8 | Expression of cyclooxygenase-2 (Cox-2) in human esophageal cancer and in vitro inhibition by a specific Cox-2 inhibitor, NS-398 显示文摘 | Yu H P Shi L Y Lu W H | 2004 | J Gastroenterol Hepatol2004,19,6: | 1 |
| 9 | A novel drought-inducible gene,A TAF1,encodes a NAC family protein that negatively regulates the expression of stress-responsive genes in Arabidopsis显示文摘 | LU P L CH EN N Z AN R SU Z QI B S REN F CHEN J WANG X C | 2007 | Plant Molecular Biology2007,63,2: | 1 |
| 10 | Long-distance growth and connec- tivity of neural stem cells after severe spinal cord injury 显示文摘 | Lu P Wang Y Graham L | 2012 | Cell2012,150,6: | 1 |
| 11 | Indirect Inverse Substruc- turing Method for Multibody Product Transport System with Rigid and Flexible Coupling显示文摘 | WANG J LU L X QIAN P J | 2015 | Shock and Vibration2015,,: | 1 |
| 12 | Detection of asymmetric giaucomatous damage using automated pupillography, the swinging flashlight method and the magnified-assisted swinging flashlight method 显示文摘 | WAISBOURD M LEE B ALI MH LU L MARTINEZ P FARIA B | 2015 | Eye (Lond)2015,29,10: | 1 |
| 13 | Banana polyphenol oxidase: occurrence and change of polypheno| o~idase activity in some banana cultivars during fruit development 显示文摘 | YangC P NongZR LuJL LU L Xu J S Han YZ Li Y J Fujita S | 2004 | Food Science Technology2004,10,1: | 1 |
| 14 | Structure and photophysical properties of europium complexes of succinamic acid and 1, 10-phenanthroline 显示文摘 | Zheng X J Jin L P Wang Z M Yan C H Lu S Z Li Q | 2003 | Polyhedron2003,22,2: | 1 |
| 15 | Dependence of Properties of N-Al Codoped p-Type ZnO Thin Films on Hrowth Temperature显示文摘 | Lu J G Zhu L P Ye Z Z | 2005 | Applied Surface Science2005,245,: | 1 |
| 16 | Conditioning including antithymocyte globulin followed by unmanipulated HLA- mismatched/haploidentical blood and marrow transplanta- tion can achieve comparable outcomes with HLA-identical sibling transplantation 显示文摘 | Lu D P Dong L Wu T | 2006 | Blood2006,107,8: | 1 |
| 17 | Lipase bound cellulose nanofibrous membrane via cibacron blue F3GA affinity ligand显示文摘 | Lu P Hsieh Y L | 2009 | Journal of Membrane Science2009,330,: | 1 |
| 18 | Enhanced experimental corneal neovascularization along with aberrant angiogenic factor expression in the absence of IL-1 receptor antagonist显示文摘 | Lu P Li L Liu G | | 0,,: | 1 |
| 19 | Dynamical behaviors of delayed neural network systems with discontinuous activation functions显示文摘 | Lu W L Chen T P | | 0,,03: | 1 |
| 20 | Experimental analysis of control loops with different delay times in the supply air system of a radiator test rig显示文摘 | Chen Y P Zhang J L Lu Z | 2011 | Energy and Buildings2011,43,1: | 1 |