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| 1 | NbN superconducting nanowire single photon detector with efficiency over 90% at 1550 nm wavelength operational at compact cryocooler temperature显示文摘The rapid development of superconducting nanowire single-photon detectors over the past decade has led to numerous advances in quantum information technology. The record for the best system detection efficiency at an incident photon wavelength of 1550 nm is 93%. This performance was attained from a superconducting nanowire single-photon detector made of amorphous WSi; such detectors are usually operated at sub-Kelvin temperatures. In this study, we first demonstrate superconducting nanowire single-photon detectors made of polycrystalline NbN with system detection efficiency of 90.2% for 1550-nm-wavelength photons at2.1 K, accessible with a compact cryocooler. The system detection efficiency saturated at 92.1% when the temperature was lowered to 1.8 K. We expect the results lighten the practical and high performance superconducting nanowire single-photon detectors to quantum information and other high-end applications. | WeiJun Zhang LiXing You Hao Li Jia Huang ChaoLin Lv Lu Zhang XiaoYu Liu JunJie Wu Zhen Wang XiaoMing Xie | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，12： | 9 |
| 2 | Experimental Gaussian Boson sampling显示文摘Gaussian Boson sampling(GBS) provides a highly efficient approach to make use of squeezed states from parametric down-conversion to solve a classically hard-to-solve sampling problem. The GBS protocol not only significantly enhances the photon generation probability, compared to standard Boson sampling with single photon Fock states, but also links to potential applications such as dense subgraph problems and molecular vibronic spectra. Here, we report the first experimental demonstration of GBS using squeezed-state sources with simultaneously high photon indistinguishability and collection efficiency.We implement and validate 3-, 4- and 5-photon GBS with high sampling rates of 832, 163 and 23 kHz,respectively, which is more than 4.4, 12.0, and 29.5 times faster than the previous experiments.Further, we observe a quantum speed-up on a NP-hard optimization problem when comparing with simulated thermal sampler and uniform sampler. | Han-Sen Zhong Li-Chao Peng Yuan Li Yi Hu Wei Li Jian Qin Dian Wu Weijun Zhang Hao Li Lu Zhang Zhen Wang Lixing You Xiao Jiang Li Li Nai-Le Liu Jonathan P.Dowling Chao-Yang Lu Jian-Wei Pan | 2019 | Science Bulletin2019，64，8： | 3 |
| 3 | PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway显示文摘Our previous studies have showed that C-C motif chemokine ligand 20(CCL20)advanced tumor progression and enhanced the chemoresistance of cancer cells by positively regulating breast cancer stem cell(BCSC)self-renewal.However,it is unclear whether CCL20 affects breast cancer progression by remodeling the tumor microenvironment(TME).Here,we observed that polymorphonuclear myeloid-derived suppressor cells(PMN-MDSCs)were remarkably enriched in TME of CCL20-overexpressing cancer cell orthotopic allograft tumors.Mechanistically,CCL20 activated the differentiation of granulocyte-monocyte progenitors(GMPs)via its receptor C-C motif chemokine receptor 6(CCR6)leading to the PMN-MDSC expansion.PMN-MDSCs from CCL20-overexpressing cell orthotopic allograft tumors(CCL20-modulated PMN-MDSCs)secreted amounts of C-X-C motif chemokine ligand 2(CXCL2)and increased ALDH+BCSCs via activating CXCR2/NOTCH1/HEY1 signaling pathway.Furthermore,C-X-C motif chemokine receptor 2(CXCR2)antagonist SB225002 enhanced the docetaxel(DTX)effects on tumor growth by decreasing BCSCs in CCL20high-expressing tumors.These findings elucidated how CCL20 modulated the TME to promote cancer development,indicating a new therapeutic strategy by interfering with the interaction between PMN-MDSCs and BCSCs in breast cancer,especially in CCL20high-expressing breast cancer. | Rui Zhang Mengxue Dong Juchuanli Tu Fengkai Li Qiaodan Deng Jiahui Xu Xueyan He Jiajun Ding Jie Xia Dandan Sheng Zhaoxia Chang Wei Ma Haonan Dong Yi Zhang Lixing Zhang Lu Zhang Suling Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 4 | Effect of microstructure and inclusions on hydrogeninduced cracking susceptibility and hydrogen trappingefficiency of X120 pipeline steel显示文摘 | HUANG F LIU J DENG Z J CHENG J H LU Z H LIX J | 2010 | Materials Scienceand Engineering2010，527，69： | 1 |
| 5 | Stabilization of vascular endothelia growth factor mRNA by hypoxia-inducible factor显示文摘 | LU H LUO Y | 2002 | Biochem Biophys Res Commun2002，291，4： | 1 |
| 6 | Multi-innovation stochastic gradient algorithms for dual-rate sampled systems with preload nonlinearity显示文摘 | Jing Chert Lixing Lu Ruifeng Ding | 2013 | Applied Mathematics Letters2013，26，1： | 1 |
| 7 | The inhibitory role of Co2 : on c: - glucosidase: Inhibition kinetics and molecular dynamics simula- tion integration study 显示文摘 | LiX Lu Z R Shen D | 2014 | Process Biochemistry2014，49，： | 1 |
| 8 | Real-time image-based Chinese ink painting rendering显示文摘 | Dong Lixing Lu Shufang Jin Xiaogang | 2014 | Multimedia Tools and Applications2014，69，3： | 1 |
| 9 | Photon-counting distributed free-space spectroscopy显示文摘Spectroscopy is a well-established nonintrusive tool that has played an important role in identifying and quantifying substances,from quantum descriptions to chemical and biomedical diagnostics.Challenges exist in accurate spectrum analysis in free space,which hinders us from understanding the composition of multiple gases and the chemical processes in the atmosphere.A photon-counting distributed free-space spectroscopy is proposed and demonstrated using lidar technique,incorporating a comb-referenced frequency-scanning laser and a superconducting nanowire single-photon detector.It is suitable for remote spectrum analysis with a range resolution over a wide band.As an example,a continuous field experiment is carried out over 72 h to obtain the spectra of carbon dioxide(CO_(2))and semi-heavy water(HDO,isotopic water vapor)in 6 km,with a range resolution of 60 m and a time resolution of 10 min.Compared to the methods that obtain only column-integrated spectra over kilometer-scale,the range resolution is improved by 2-3 orders of magnitude in this work.The CO_(2)and HDO concentrations are retrieved from the spectra acquired with uncertainties as low as±1.2%and±14.3%,respectively.This method holds much promise for increasing knowledge of atmospheric environment and chemistry researches,especially in terms of the evolution of complex molecular spectra in open areas. | Saifen Yu Zhen Zhang Haiyun Xia Xiankang Dou Tengfei Wu Yihua Hu Manyi Li Mingjia Shangguan Tianwen Wei Lijie Zhao Lu Wang Pu Jiang Chengjun Zhang Lixing You Leigang Tao Jiawei Qiu | 2021 | Light(Science & Applications)2021，10，11： | 1 |
| 10 | Supercontinuum single-photon detector using multilayer superconducting nanowires显示文摘High-efficiency superconducting nanowire single-photon detectors(SNSPDs), which have numerous applications in quantum information systems, function by using the optical cavity and the ultrasensitive photon response of their ultra-thin superconducting nanowires. However, the wideband response of superconducting nanowires is limited due to the resonance of the traditional optical cavity. Here, we report on a supercontinuum SNSPD that can efficiently detect single photons over an ultra-broad spectral range from visible to mid-infrared light. Our detection approach relies on using multiple cavities with well-separated absorbed resonances formed by fabricating multilayer superconducting nanowires on metallic mirrors with silica acting as spacer layers. Thus, we are able to extend the absorption spectral bandwidth while maintaining considerable efficiency, as opposed to a conventional single-layer SNSPD. Our calculations show that the proposed supercontinuum SNSPD exhibits an extended absorption bandwidth with increased nanowire layers. Its absorption efficiency is greater than 70%over the entire range from 400 to 2500 nm(or 400 to 3000 nm), when using two-layer(or three-layer) nanowires.As a proof of principle, the SNSPD with bilayer nanowires is fabricated based on the proposed detector architecture with simplified geometrical parameters. The detector achieves broadband detection efficiency over 60%from 950 to 1650 nm. This type of detector may replace multiple narrow band detectors in a system and find uses in the emerging and rapidly advancing field of atomic and molecular broadband spectroscopy. | HAO LI YONG WANG LIXING YOU HEQING WANG HUI ZHOU PENG HU WEIJUN ZHANG XIAOYU LIU XIAOYAN YANG LU ZHANG ZHEN WANG XIAOMING XIE | 2019 | Photonics Research2019，7，12： | 1 |
| 11 | Fragment Anisotropy of Complete Fusion-Fission at Subbarrier Energies for the ^(11)B+^(238)U and ^(12)C+^(237)Np Reactions显示文摘Fission fragment angular distributions have been measured for the reactions ^(11)B+^(238)U,(12)C+^(237)Np at near-and sub-barrier energies,and ^(16)O+^(238)U at 90 MeV.The complete fusion-fission and transfer-fission were separated as components in the whole energy region in this experiment.The influence of pre-scission neutron emission on fragment anisotropies has been considered.This effect leads to increase of the anisotropies when compared with the results obtained under the assumption of first chance fission.However,the anomalous anisotropies still persist. | ZHANG Huanqiao LIU Zuhua XU Jincheng QIAN Xing CHEN Shaolin LU Lixing | 1992 | Chinese Physics Letters1992，9，6： | 0 |
| 12 | Deformable double-shelled hollow mesoporous organosilica nanocapsules:A multi-interfacial etching strategy显示文摘Multishelled hollow structures have drawn increasing interest because of their peculiar compartmentation environments and physicochemical properties.In this work,deformable double-shelled hollow mesoporous o rganosilica nanocapsules(DDHMONs)were succes s fully synthesized by a multi-interfacial etching strategy.The obtained DDHMONs have a double-shelled structure with aninorganic-organic hybrid framework,a uniform outer layer(~320 nm)and inner layer(~180 nm),ordered mesochannels(~2.21 nm),and a large specific surface area(~1233 m^(2)/g).In vitro toxicity tests show that the DDHMONs have excellent biocompatibility when coincubated with human breast cancer cells.In addition,the anti cancer substance doxorubicin(DOX)can be highly loaded in DDHMONs(~335μg/mg).The results from flow cytometry together with confocal laser scanning microscopy show that DOX can be efficiently delivered into MCF-7 cells by DDHMONs,thus improving chemotherapeutic efficiency and demonstrating that DDHMONs have potential nanomedicine applications as anticancer agents. | Zhihao Feng Zhaogang Teng Yuyuan Shi Wenhui Shi Xiaodan Su Guangming Lu Lianhui Wang Lixing Weng | 2021 | Chinese Chemical Letters2021，32，3： | 0 |
| 13 | Application of steel fiber shotcrete technology in soft rock roadway support显示文摘Steel fiber shotcrete is widely used as a new composite material in water conservancy and hydropower projects,Highway Tunnel,Mine Roadway,etc.Support Works.by analyzing the characteristics of steel fiber shotcrete technology,with the actual project of Qinghai mine as background,Introduction Steel Fiber spray material selection for coagulation technology,ratio design,Construction equipment and spraying construction process and essentials.actually works well,can be class works like construction for reference. | daiju Narita Lu Lixing Ninzhidan Ma Junnan | 2014 | Concrete Technology2014，3，1： | 0 |
| 14 | A Distributionally Robust Optimization Method for Passenger Flow Control Strategy and Train Scheduling on an Urban Rail Transit Line显示文摘Regular coronavirus disease 2019(COVID-19)epidemic prevention and control have raised new require-ments that necessitate operation-strategy innovation in urban rail transit.To alleviate increasingly seri-ous congestion and further reduce the risk of cross-infection,a novel two-stage distributionally robust optimization(DRO)model is explicitly constructed,in which the probability distribution of stochastic scenarios is only partially known in advance.In the proposed model,the mean-conditional value-at-risk(CVaR)criterion is employed to obtain a tradeoff between the expected number of waiting passen-gers and the risk of congestion on an urban rail transit line.The relationship between the proposed DRO model and the traditional two-stage stochastic programming(SP)model is also depicted.Furthermore,to overcome the obstacle of model solvability resulting from imprecise probability distributions,a discrepancy-based ambiguity set is used to transform the robust counterpart into its computationally tractable form.A hybrid algorithm that combines a local search algorithm with a mixed-integer linear programming(MILP)solver is developed to improve the computational efficiency of large-scale instances.Finally,a series of numerical examples with real-world operation data are executed to validate the pro-posed approaches. | Yahan Lu Lixing Yang Kai Yang Ziyou Gao Housheng Zhou Fanting Meng Jianguo Qi | 2022 | Engineering2022，8，5： | 0 |
| 15 | Optimization Analysis of the Mixing Chamber and Diffuser of Ejector Based on Fano Flow Model显示文摘An improved model to calculate the length of the mixing chamber of the ejector was proposed on the basis of the Fano flow model,and a method to optimize the structures of the mixing chamber and diffuser of the ejector was put forward.The accuracy of the model was verified by comparing the theoretical results calculated using the model to experimental data reported in literature.Variations in the length of the mixing chamber L_(m) and length of the diffuser L_(d) with respect to variations in the outlet temperature of the ejector T_(c),outlet pressure of the ejector p_(c),and the expansion ratio of the pressure of the primary flow to that of the secondary flow p_(g)/p_(e) were investigated.Moreover,variations in L_(m) and L_(d) with respect to variations in the ratio of the diameter of the throat of the motive nozzle to the diameter of the mixing chamber d_(g0)/d_(c3) and ratio of the outlet diameter of the diffuser to the diameter of themixing chamber d_(c)/d_(c3) were investigated.The distribution of flow fields in the ejector was simulated.Increasing L_(m) and d_(c3) reduced T_(c) and p_(c).Moreover,reducing p_(g)/p_(e) or d_(g0)/d_(c3) reduced T_(c) and p_(c).The length of the mixed section L_(m2),which was determined on the basis of the Fano flow model,increased as pg increased and decreased as d_(c3) increased.The mixing length L_(m1),which was considered the primary flow expansion,showed the opposite trend with that of L_(m2).Moreover,Ld increased as p_(g)/p_(e) and d_(c)/d_(c3) increased.When the value of d_(c) was 1.8 to 2.0 times as high as that of dc3,the semi-cone angle of the diffuser ranged between 6°and 12°.At a constant dc/dc3,decreasing T_(c) and pc increased Ld. | Lixing Zheng Weibo Wang Yiyan Zhang Lingmei Wang Wei Lu | 2022 | Computer Modeling in Engineering & Sciences2022，，10： | 0 |
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