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| 1 | The relation between HLA-DQA1 genes and genetic susceptibility to duodenal ulcer in Wuhan Hans显示文摘AIM To study the genetic susceptibility of HLA-DQA1 alleles to duodenal ulcer in Wuhan Hans.METHODS Seventy patients with duodenalulcer and fifty healthy controls were examinedfor HLA-DQA1 genotypes.HLA-DQA1 typing wascarried out by digesting the locus specificpolymerase chain reaction amplified productswith alleles specific restriction enzymes(PCR-RFLP),i.e.,Apal Ⅰ,Bsaj Ⅰ,Hph Ⅰ,Fok Ⅰ,Mbo Ⅱ and Mnl Ⅰ.RESULTS The allele frequencies of DQA1 * 0301and DQA1 * 0102 in patients with duodenal ulcerwere significantly higher and lower respectivelythan those in healthy controls(0.40 vs 0.20,P = 0.003,mcorret = 0.024)and(0.05 vs 0.14,P = 0.012,but Pcorret>0.05),respectively.CONCLUSION DQA1 * 0301 is a susceptiblegene for duodenal ulcer in Wuhan Hans,andthere are immunogenetic differences in HLA-DQA1 locus between duodenal ulcer patients andhealthy controls. | Du YP Deng CS Lu DY Huang MF Guo SF Hou W | 2000 | World Journal of Gastroenterology2000，6，1： | 37 |
| 2 | Effects of heat shock on change of HSC70/HSP68,acid and alkaline phosphatases before and after rat partial hepatectomy显示文摘INTRODUCTIONOnly the liver has the great capability ofregeneration in mammal.Few hepatocytes are inthe phase of division in the normal liver of an adultmammal (including human beings),but theremaining hepatocytes can be induced to proliferatequickly by partial hepatectomy (PH),and,to somedegree,they stop dividing and re-differentiate intocells functioning as hepatocytes.This shows | Lu AL Xu CS | 2000 | World Journal of Gastroenterology2000，6，5： | 27 |
| 3 | A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection显示文摘Interleukin-17(IL-17),a member of the IL-17 cytokine family,plays a crucial role in mediating the immune response against extracellular bacteria and fungi in the lung.Although there is increasing evidence that IL-17 is involved in protective immunity against H1 and H3 influenza virus infections,little is known about the role of IL-17 in the highly pathogenic H5N1 influenza virus infection.In this study,we show that H5N1-infected IL-17 knockout(KO)mice exhibit markedly increased weight loss,more pronounced lung immunopathology and significantly reduced survival rates as compared with infected wild-type controls.Moreover,the frequency of B cells in the lung were substantially decreased in IL-17 KO mice after virus infection,which correlated with reduced CXCR5 expression in B cells and decreased CXCL13 production in the lung tissue of IL-17 KO mice.Consistent with this observation,B cells from IL-17 KO mice exhibited a significant reduction in chemokine-mediated migration in culture.Taken together,these findings demonstrate a critical role for IL-17 in mediating the recruitment of B cells to the site of pulmonary influenza virus infection in mice. | Xiaohui Wang Chris CS Chan Min Yang Jun Deng Vincent KM Poon Virtual HC Leung King-Hung Ko Jie Zhou Kwok Yung Yuen Bo-Jian Zheng Liwei Lu | 2011 | Cellular & Molecular Immunology2011，8，6： | 2 |
| 4 | Differential diagnosis of Parkinson's disease and vascular parkinsonism by 99mTc-TRODAT-1显示文摘 | Tzen KY Lu CS Yen TC | 2001 | J Nucl Med2001，42，3： | 2 |
| 5 | Carbamazepine-induced toxic effects and HLA-B* 1502 screening in Taiwan 显示文摘 | Chen P Lin JJ Lu CS | 2011 | N Engl J Med2011，364，12： | 1 |
| 6 | A common missense variant in the LRRK2 gene,Gly2385Arg,associated with Parkinson's disease risk in Taiwan显示文摘 | Di Fonzo A Wu-Chou YH Lu CS | 2006 | Neurogenetics2006，7，3： | 1 |
| 7 | Preoperative dexmedetomidine pre- vents touminquet-induced hypertension in orthopedic operation dur- ing anesthesia 显示文摘 | Lu Y Zhang Y Dong CS | 2013 | Kaohsiung J Med2013，29，5： | 1 |
| 8 | Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas显示文摘 | Rhee CS Sen M Lu D | 2002 | Oncogene2002，21，43： | 1 |
| 9 | The accuracy of video imaging prediction in soft tissue outcome after bimaxillary orthognathic surgery 显示文摘 | Lu CH Ko EW Huang CS | 2003 | J Oral Maxillofac Surg2003，61，3： | 1 |
| 10 | Identification of polyclonal and monoclonal antibodies against tissue plasminogen activator in the antiphospholipid syndrome 显示文摘 | Lu CS Horizon A A Hwang K K | 2005 | Arthritis Rheum2005，52，12： | 1 |
| 11 | Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan显示文摘 | CHEN P LIN JJ LU CS | 2011 | New England Journal of Medicine2011，364，12： | 1 |
| 12 | Cancer prevention by tea: animal studies, molecular mechanisms and human relevance显示文摘 | Yang CS Wang X Lu G | 2009 | Nat Rev Cancer2009，9，6： | 1 |
| 13 | Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas显示文摘 | Rhee CS Sen M Lu D | 2002 | Oncogene2002，21，： | 1 |
| 14 | Serial magnetic resonance imaging in patients with Balo's concentric sclerosis:natural history of lesion development显示文摘 | Chen CJ Chu NS Lu CS | 1999 | Ann Neurol1999，46，4： | 1 |
| 15 | Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas显示文摘 | Rhee CS Sen M Lu D | 2002 | Oncogene2002，21，43： | 1 |
| 16 | Technology acceptance model for wireless Internet显示文摘 | Lu J Yu CS Liu C | 2003 | Internet Research2003，13，3： | 1 |
| 17 | Total knee arthroplasty in the presence of severe flexion contracture 显示文摘 | Lu Hou-shan Mow CS Lin Jian-hao | 1999 | J Arthroplasty1999，7，： | 1 |
| 18 | Determinants of Accepting Wireless Mobile Data Services in China显示文摘 | Lu J Liu C Yu CS | 2008 | Information & Management2008，，45： | 1 |
| 19 | Leptin inhibits 1-methyl-4-phenylpyridinium-induced cell death in SH-SY5Y cells显示文摘 | Lu J Park CS Lee SK | 2006 | Neurosci Lett2006，407，3： | 1 |
| 20 | Does the multidimensional grading system (BODE) correspond to differences in health status of patients with COPD?显示文摘 | Ong KC Lu SJ Soh CS | 2006 | lnt J Chron Obstruct Pulmon Dis2006，1，1： | 1 |
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