|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The relation between HLA-DQA1 genes and genetic susceptibility to duodenal ulcer in Wuhan Hans显示文摘AIM To study the genetic susceptibility of HLA-DQA1 alleles to duodenal ulcer in Wuhan Hans.METHODS Seventy patients with duodenalulcer and fifty healthy controls were examinedfor HLA-DQA1 genotypes.HLA-DQA1 typing wascarried out by digesting the locus specificpolymerase chain reaction amplified productswith alleles specific restriction enzymes(PCR-RFLP),i.e.,Apal Ⅰ,Bsaj Ⅰ,Hph Ⅰ,Fok Ⅰ,Mbo Ⅱ and Mnl Ⅰ.RESULTS The allele frequencies of DQA1 * 0301and DQA1 * 0102 in patients with duodenal ulcerwere significantly higher and lower respectivelythan those in healthy controls(0.40 vs 0.20,P = 0.003,mcorret = 0.024)and(0.05 vs 0.14,P = 0.012,but Pcorret>0.05),respectively.CONCLUSION DQA1 * 0301 is a susceptiblegene for duodenal ulcer in Wuhan Hans,andthere are immunogenetic differences in HLA-DQA1 locus between duodenal ulcer patients andhealthy controls. | Du YP Deng CS Lu DY Huang MF Guo SF Hou W | 2000 | World Journal of Gastroenterology2000，6，1： | 37 |
| 2 | A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection显示文摘Interleukin-17(IL-17),a member of the IL-17 cytokine family,plays a crucial role in mediating the immune response against extracellular bacteria and fungi in the lung.Although there is increasing evidence that IL-17 is involved in protective immunity against H1 and H3 influenza virus infections,little is known about the role of IL-17 in the highly pathogenic H5N1 influenza virus infection.In this study,we show that H5N1-infected IL-17 knockout(KO)mice exhibit markedly increased weight loss,more pronounced lung immunopathology and significantly reduced survival rates as compared with infected wild-type controls.Moreover,the frequency of B cells in the lung were substantially decreased in IL-17 KO mice after virus infection,which correlated with reduced CXCR5 expression in B cells and decreased CXCL13 production in the lung tissue of IL-17 KO mice.Consistent with this observation,B cells from IL-17 KO mice exhibited a significant reduction in chemokine-mediated migration in culture.Taken together,these findings demonstrate a critical role for IL-17 in mediating the recruitment of B cells to the site of pulmonary influenza virus infection in mice. | Xiaohui Wang Chris CS Chan Min Yang Jun Deng Vincent KM Poon Virtual HC Leung King-Hung Ko Jie Zhou Kwok Yung Yuen Bo-Jian Zheng Liwei Lu | 2011 | Cellular & Molecular Immunology2011，8，6： | 2 |
| 3 | Preparation and mechanical properties of nanocomposites of poly ( D, L-lactide) with Ca-deficient hydroxyapa- tite nanocrystals显示文摘 | Deng XM Hao JY Wang CS | 2001 | Biomaterials2001，22，21： | 1 |
| 4 | Expression of angiopoietin-2 is corrlated with vascularization and tumor size in human coloreetal adenocarcinoma显示文摘 | Wang HI Deng CS Lin J | | 0，，： | 1 |
| 5 | Chronic colitis by inhibiting expression of cyclooxygenase-2 显示文摘 | Jiang H Deng CS Zhang M | 2006 | World J Gastroenterol2006，12，24： | 1 |
| 6 | Defining adipose tissue-derived stem cells in tissue and in euhure显示文摘 | Lin CS Xin ZC Deng CH | 2010 | Hi stol Histopathol2010，25，6： | 1 |
| 7 | Expression of angiopoietin-2 is correlated with vascularization and tumor size in human colorectal adenocarcinoma显示文摘 | Wang HL Deng CS Lin J | 2007 | Tohoku J Exp Med2007，213，1： | 1 |
| 8 | Alterations in NF-kappa B function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappa B显示文摘 | Seitz Cs Lin Q Deng H | 1998 | Proc Natl Acad Sci USA1998，95，5： | 1 |
| 9 | Aberrant expression levels of MTA1 and RECK in nasopharyngeal carcinoma: association with metastasis, recurrence, and prognosis显示文摘 | Deng YF Zhou DN Ye CS | 2012 | Ann Otol Rhinol Laryngol2012，121，7： | 1 |
| 10 | Astigmatism associated with experimentally induced myopia or hyperopia in chickens显示文摘 | Kee CS Deng L | 2008 | Invest Ophthalmol Vis Sci2008，49，： | 1 |
| 11 | Serological investigations on West Nile virus in birds and horses in Shanghai, China 显示文摘 | Lan DL Wang CS Deng B Zhou JP Cui L Tang C Yue H Hua XG | 2013 | Epidemiol Infect2013，141，3： | 1 |
| 12 | CD4+Th-APC with acquired peptide/MHC class I and IIcomplexes stimulate type 1 helper CD4+and central memoryCD8+T cell responses显示文摘 | Umeshappa CS Huang H Xie Y Wei Y Mulligan SJ Deng Y | 2009 | J Immunol2009，182，1： | 1 |
| 13 | Preparation and mechanicalproperties of nanocomposites of poly(D,L-lactide)with Ca-de-ficient hydroxyapatite nanocrystals显示文摘 | Deng XM Hao JY WANG CS | 2001 | Biomat2001，22，21： | 1 |
| 14 | Hexbromocyclododecane-induced developmental toxicity and apoptosis in zebrafish embryos显示文摘 | Deng J Yu LQ Liu CS | 2009 | Aquatic Toxicology2009，93，5： | 1 |
| 15 | Pharmacological effect of tanshinone显示文摘 | Yang Y Deng CS | 1999 | J Hu- bei TCM1999，21，6： | 1 |
| 16 | Clinical analysis of ultrasonic emulsiifcation withintraocular lens implantation treating uveitis complicated cataract显示文摘 | Deng CS | 2011 | Contemporary Medicine2011，17，8： | 1 |
| 17 | Analysis of first-derivative based Q RS detection algorithms 显示文摘 | Arzeno NM Deng Zhide Poon CS | 2008 | IEEE Transactions on Biomedical Engineering2008，55，2： | 1 |
| 18 | Renal vasoconstriction during inhibition of NO synthase:effects of dietary salt显示文摘 | Deng X Welch WJ Wilcox CS | 1994 | Kidney Int1994，46，： | 1 |
| 19 | BMP type I receptor inhibition reduces heterotopic ossification 显示文摘 | Yu PB Deng DY Lai CS | 2008 | Nat Mvd2008，14，： | 1 |
| 20 | HLA-DRB1 allete polymophisms in genetic susceptibility to esophageal carcinoma显示文摘 | Lin J Deng CS Sun J | 2003 | World J Gastroenterol2003，9，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员