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| 1 | 短期针刺足三里对脂多糖诱导的大鼠急性肺损伤的预防作用(英文)显示文摘目的:研究短期手法针刺足三里治疗对脂多糖诱导的实验性大鼠急性肺损伤的预防作用。方法:根据是否进行脂多糖刺激及采用的针刺方法的不同,将32只 Wistar 大鼠随机分为4组,即正常对照组、模型组、假针刺组和针刺组,每组8只。假针刺组和针刺组大鼠行手法针刺治疗,连续治疗4 d,每次 5 min。第4天针刺后采用脂多糖刺激诱导大鼠急性肺损伤。第5天,收集外周血、支气管肺泡灌洗液和骨髓等进行白细胞计数。结果:血细胞计数和支气管肺泡灌洗液细胞计数提示,针刺可减轻急性肺损伤大鼠的炎性反应,假针刺也有轻微的效果。正常对照组和模型组大鼠无明显的炎性反应。与正常对照组比较,模型组肺泡灌洗液中细胞计数增加;与假针刺组比较,针刺组肺泡灌选液中细胞计数减少,但差异没有统计学意义。结论:预防性手法针刺足三里可减轻脂多糖诱导的大鼠急性肺损伤,但其相关免疫机制仍待进一步的研究。 | Arthur de Sá FERREIRA Januário Gomes Mourāo e LIMA Tatiana Pereira Teixeira FERREIRA Camila Madeira Tavares LOPES Rubens MEYER | 2009 | 中西医结合学报2009，7，10： | 21 |
| 2 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 3 | 100%RAP的温拌再生沥青混合料的路用性能研究显示文摘沥青路面施工行业一直存在较大的节能减排的压力。一方面可以通过降低沥青混合料的拌和、摊铺温度来实现;另一方面,废旧沥青路面材料(RAP)的回收也是一个可行方案,既可减少废物的生产,同时又有利于减少资源的消耗。该文开展了一项温拌沥青配合使用RAP集料的研究:在低于常规热拌混合料工艺温度的条件下,生产含有100%RAP温拌再生沥青混合料。使用100%RAP和不同乳化沥青含量制备几种温拌再生沥青混合料(WMRA),并通过室内试验对它们的性能进行了评估,如水敏感性、劲度模量、抗疲劳性能和抗车辙性能。结果表明:这些WMRA可替代常规热拌沥青混合料用于公路路面。 | 肖庆一 张靖洁 李宁利 张萌骐 Marisa Dinis-Almeida Joo CastroGomes Cesare Sangiorgi Salah E.Zoorob Márcia Lopes Afonso | 2017 | 中外公路2017，37，3： | 6 |
| 4 | No evidence of HPV DNA in esophageal squamous cell carcinoma in a population of Southern Brazil显示文摘AIM:To investigate the association between human papillomavirus(HPV)and esophageal squamous cell carcinoma(ESCC)in southern Brazil.METHODS:We studied 189 esophageal samples from125 patients from three different groups:(1)102 biopsies from 51 patients with ESCC,with one sample from the tumor and another from normal esophageal mucosa distant from the tumor;(2)50 esophageal biopsies from 37 patients with a previous diagnosis of head and neck squamous cell carcinoma(HNSCC);and(3)37 biopsies from esophageal mucosa with normal appearance from 37 dyspeptic patients,not exposed to smoking or alcohol consumption.Nested-polymerase chain reaction(PCR)with the MY09/11 and GP5/6 L1primers was used to detect HPV L1 in samples fixed in formalin and stored in paraffin blocks.All PCR reactions were performed with a positive control(cervicovaginal samples),with a negative control(Human Genomic DNA)and with a blank reaction containing all reagents except DNA.We took extreme care to prevent DNA contamination in sample collection,processing,and testing.RESULTS:The histological biopsies confirmed the diagnosis of ESCC in 52 samples(51 from ESCC group and 1 from the HNSCC group)and classified as well differentiated(12/52,23.1%),moderately differentiated(27/52,51.9%)or poorly differentiated(7/52,13.5%).One hundred twenty-eight esophageal biopsies were considered normal(51 from the ESCC group,42 from the HNSCC group and 35 from dyspeptic patients).Nine had esophagitis(7 from the HNSCC and 2 from dyspeptic patients).Of a total of 189 samples,only 6 samples had insufficient material for PCR analysis:1 from mucosa distant from the tumor in a patient with ESCC,3from patients with HNSCC and 2 from patients without cancer.In 183 samples(96.8%)GAPDH,G3PDH and/orβ-globin were amplified,thus indicating the adequacy of the DNA in those samples.HPV DNA was negative in all the 183 samples tested:52 with ESCC,9 with esophagitis and 122 with normal esophageal mucosa.CONCLUSION:There was no evidence of HPV infection in different ESCC from southern Brazil. | Luís Carlos Moreira Antunes Joo Carlos Prolla Antonio de Barros Lopes Marta Pires da Rocha Renato Borges Fagundes | 2013 | World Journal of Gastroenterology2013，19，39： | 4 |
| 5 | High C-reactive protein in Crohn’s disease patients predicts nonresponse to Infliximab treatment显示文摘 | Fernando Magro Eduardo Rodrigues-Pinto Jo?o Santos-Antunes Filipe Vilas-Boas Susana Lopes Amadeu Nunes Claudia Camila-Dias Guilherme Macedo | 2013 | Journal of Crohn’s and Colitis2013，，： | 2 |
| 6 | Schistosoma mansoni: In vitro schistosomicidal activity ofpiplartine 显示文摘 | de Moraes J Nascimento C Lopes P O M V | 2011 | Exp Parasitol2011，127，2： | 1 |
| 7 | Effects of incorporating polycaprolactone and flax fiber into glycerol-plasticized pea starch 显示文摘 | OLAYIDE O F LOPE G T SATYANARAYAN P | 2011 | J Polym Environ2011，19，： | 1 |
| 8 | sensilla basiconica and their detaction eucalyptus woodborer, Phoracantha ( Coleoptera: Cerambycidae ) 显示文摘 | Lopes O Barata EN Mustaparta H | 2002 | Development2002，31，1： | 1 |
| 9 | External validation of a classification for methylene blue magnification chromoendoscopy in premalignant gastric lesions显示文摘 | Miguel Areia Pedro Amaro Mário Dinis-Ribeiro Maria Augusta Cipriano Carol Marinho Altamiro Costa-Pereira Carlos Lopes Luís Moreira-Dias José Manuel Rom?ozinho Hermano Gouveia Diniz Freitas Maximino Correia Leit?o | 2008 | Gastrointestinal Endoscopy2008，，7： | 1 |
| 10 | An evaluation of quantitative and qualitative methods of predicting the 2002 FIFA World Cup显示文摘 | O'Donoghue P G Dubitzky W Lopes P | 2004 | Journal of Sports Sciences2004，22，： | 1 |
| 11 | Carcinoma of the papilla of vater: Are endoscopic appearance and endoscopic biopsy discordant?显示文摘 | Michelle Lucinda DeOliveira M.D. Tarcisio Trivi?o M.D. Ph.D. Gaspar de Jesus Lopes Filho M.D. Ph.D | 2006 | Journal of Gastrointestinal Surgery2006，，8： | 1 |
| 12 | Geometrical nonlinearities on the static analysis of highly flexible steel cable-stayed bridges 显示文摘 | Freire A M S Negrao J H O Lopes A V | 2006 | Computers and Struc- tures2006，，84： | 1 |
| 13 | Effect of specific exercise training on bone mineral density in women with postmenopausal osteopenia or osteoporosis显示文摘 | de Matos O Lopes da Silva DJ Martinez de Oliveira J | | 0，，09： | 1 |
| 14 | Multiresponse Optimization and Pareto Frontiers显示文摘 | Nuno Ricardo Costa Jo?o Louren?o Zulema Lopes Pereira | 2011 | Qual Reliab Engng Int2011，，7： | 1 |
| 15 | Geo- metrical Nonlinearities on the Static Analysis of Highly Flexible Steel Cable-stayed Bridges显示文摘 | FREIRE A M S NEGRAO J H O LOPES A V | 2006 | Com puters and Structures2006，84，3132： | 1 |
| 16 | Service restoration on distribution systems using multi-microgrids显示文摘 | Resende F O Gil N J Lopes J A | 2011 | European Transactions of Electrical Power2011，21，2： | 1 |
| 17 | Nitinol biliary stent versus surgery for palliation of distal malignant biliary obstruction显示文摘 | Castano R Lopes TL Alvarez O | 2010 | Surg Endosc2010，24，： | 1 |
| 18 | Geometrical nonlinearities on the static analysis of highly flexible steel cable-stayed bridges 显示文摘 | Freire A M S Negrao J H O lopes A V | 2006 | Computers and Struc- tures2006，84，3132： | 1 |
| 19 | Adenosine and related drugs in brain diseases:present and future in clinical trials显示文摘 | LOPES L V SEBAST(A)O A M RIBEIRO J A | | 0，，08： | 1 |
| 20 | A Phase II trial of split, low-dose docetaxel and low-dose capecitabine: a tolerable and efficacious regimen in the first-line treatment of patients with HER2/neu-negative metastatic breast cancer显示文摘 | SILVA O LOPES G MORGENZSTERN D | 2008 | Clin Breast Cancer2008，8，2： | 1 |
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