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1526篇 您的检索式:作者名="LINDAHL"
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1七个发达国家卫生系统的领导与治理显示文摘本文运用结构式调查方法,探讨了澳大利亚、英国、德国、荷兰、挪威、瑞典和瑞士七个发达国家卫生系统的领导和治理情况。领导与治理模式包含三项基本职能:优先顺序设置、绩效监管和问责制。各国卫生系统的领导和治理方法存在着显著差异,零散并略显随意。虽然各国在卫生系统的总体目标上达成了共识,但设置优先顺序的途径各不相同。成本效益分析作为设置卫生系统运行优先顺序的一个主要方法被各国加以广泛运用,但并未发挥核心作用。各国虽然处于不同的发展阶段,但绩效监管却能广泛吸收有益意见。问责制特别是在最优方法的不确定性方面,各国之间的差异最大。大多数情况下,市场机制、选举程序、直接经济激励以及专业监督与控制等几种不同问责机制的组合可能更为合适。而且这些机制应与优先顺序设置和绩效监管协调一致。Peter C Smith Anders Anell Reinhard Busse Luca Crivelli Judith Healy Anne Karin Lindahl Gert Westert Tobechukwu Kene 2012中国卫生政策研究2012,5,11:13
2通过贻贝养殖改善海水水质:瑞典社会的可盈利性方案显示文摘沿海水域的富营养化是一个在全球范围内需要付出巨大社会代价的严重的环境问题。在斯卡格拉克海峡东部,富营养化的降低计划通过氮输入量的减少逐步实现,但目前还不清楚如何去减少氮的输入量。其中一个可能的方法是养殖紫贻贝等滤食性生物,这种贻贝能够在生产海产品、饲料和农业肥料的同时也能够除去氮,从而将营养盐由海洋再循环到了陆地上。在瑞典西海岸的古尔马峡湾,我们对贻贝养殖可能对氮循环产生的影响进行了模拟。结果显示,该峡湾口地区氮的净输送量(溶解氮和颗粒状氮的总和)下降了20%。现有的商业贻贝养殖场已经免费提供了这种服务,但它对社会带来的利益将会远远大于这些。我们建议,不应该向贻贝饲养人支付劳动报酬,而应引入营养交换体制以提高沿海水域的状况。在这样的背景下提出了一个通过养殖贻贝来替代在吕瑟希尔社区的污水处理厂中消减氮含量的选择方案。生体毒素的聚积已被确定为瑞典的商业贻贝养殖进一步扩大方面的最大障碍,但这一问题似乎可以通过新技术和管理战略得以解决。在现有和可能的规定和支付费用的基础上,我们提出了一些可能会实现双赢的解决方案。Odd Lindahl Rob Hart Bodil Hernroth Sven Kollberg Lars-Ove Loo Lars Olrog Ann-Sofi Rehnstam-Holm Jonny Svensson Susanne Svensson Ulf Syversen 许天虎 2005AMBIO-人类环境杂志2005,34,2:7
3My Journey to DNA Repair显示文摘I completed my medical studies at the Karolinska Institute in Stockholm but have always been devoted to basic research. My longstanding interest is to understand fundamental DNA repair mechanisms in the fields of cancer therapy, inherited human genetic disorders and ancient DNA. I initially measured DNA decay, including rates of base loss and cytosine deamination. I have discovered several important DNA repair proteins and determined their mechanisms of action. The discovery of uracil-DNA glycosylase defined a new category of repair enzymes with each specialized for different types of DNA damage. The base excision repair pathway was first reconstituted with human proteins in my group. Cell-free analysis for mammalian nucleotide excision repair of DNA was also developed in my laboratory. I found multiple distinct DNA ligases in mammalian cells, and led the first genetic and biochemical work on DNA ligases Ⅰ, and Ⅳ. I discovered the mammalian exonucleases DNase Ⅲ (TREX1) and IV (FEN1). Interestingly, expression of TREX1 was altered in some human autoimmune diseases. I also showed that the mutagenic DNA adduct O6-methylguanine (O6 mG) is repaired without removing the guanine from DNA, identifying a surprising mechanism by which the methyl group is transferred to a residue in the repair protein itself. A further novel process of DNA repair discovered by my research group is the action of AlkB as an iron-dependent enzyme carrying out oxidative demethylation.Tomas Lindahl 2013Genomics, Proteomics & Bioinformatics2013,11,1:3
4HOW ARE PRODUCT-SERVICE COMBINED OFFERS PROVIDED IN GERMANY AND ITALY?ANALYSIS WITH COMPANY SIZES AND COUNTRIES显示文摘以传统的产品出售企业的一个不同方法提供产品和服务的一个新企业概念特别在生产工业正在得到更多的注意。这篇论文调查借助于产品和服务的集成的这家新企业怎么在德国和意大利被完成。另外,它根据公司尺寸分析差别。结果包括那这类企业在他们顾客的焦点激发的许多情况中并且经常由物理产品和他们的维护组成。与德国的对比,意大利的公司经常为这类提议明确地设计他们的物理产品。从分析基于尺寸差别,当拥有物理产品时,小公司被发现为这类提议完成特定的设计。在那里别似乎是开发支持如此的提议的发展的任何确定的方法或工具,在如此的方法 / 工具以内,将为更多的改编处于良好的竟技状态有空间物理产品设计。Tomohiko SAKAO Nicola NAPOLITANO Massimo TRONCI Erik SUNDIN Mattias LINDAHL 2008Journal of Systems Science and Systems Engineering2008,17,3:3
5Biomarkers of Coagulation, Inflammation, and Angiogenesis are Independently Associated with Preeclampsia显示文摘Roland Boij Judit Svensson Kristina Nilsson‐Ekdahl Kerstin Sandholm Tomas L. Lindahl Elzbieta Palonek Mats Garle G?ran Berg Jan Ernerudh Maria Jenmalm Leif Matthiesen 2012Am J Reprod Immunol2012,,3:2
6Prognostic influence of increased fibrinogen and C - reactive protein levels in unstable coronary artery disease显示文摘Toss H Lindahl B Siegbahn A 1998Eur Heart J1998,19,:1
7Markers of myocardial damage in acute coronary syndromes-therapeutic implications 显示文摘Lindahl B 2001Clinica Chimica Acta2001,311,1:1
8Periprosthetic femoral fractures classification and demographics of 1049 periprosthetic femoral fractures from the Swedish National Hip Arthroplasty Register显示文摘Lindahl H Malchau H Herberts P 2005J Arthroplasty2005,20,7:1
9Rabbit articular cartilage defects treated with autologous cultured chondrocy test显示文摘Brittberg M Nilsson A Lindahl A 1996Clin Orthop1996,326,:1
10Explaining the demand for producer services: is cost-driven externalization the major factor? 显示文摘Beyers W B Lindahl D P 1996Regional science1996,75,:1
11Microstructure of model cermets with high Mo or W content显示文摘LINDAHL P GUSTAFSON P ROLANDER U STALS L ANDREN H O 1999International Journal of Refractory Metals & Hard Materials1999,17,6:1
12Cystatin C: a novelpredictor of outcome in suspected or confirmed non-STelevationacute coro- nary syndrome显示文摘Jernberg T Lindahl B James S 2004Circulation2004,110,16:1
13Defining nutritional constraints on carbon cycling in boreal forests -- towards a less 'phytocentric' perspective显示文摘Lindahl BO Taylor AF Finlay RD 2002Plant and Soil2002,242,1:1
14Influence of arbuscular mycorrhizal mycelial exudates on soil bacterial growth and community structure 显示文摘Toljander J F Lindahl B D Paul L R 2007FEMS Microbiology Ecology2007,61,2:1
15Loss of miR-200 inhibition of Suz12 leads to poly- comb-mediated repression required for the formation and ma intenance of cancer stem cells显示文摘ILIOPOULOS D LINDAHL ALLEN M POLYTARCHOU C 2010Mol Ce112010,39,76:1
16Serial analyses of N-terminal pro-B-type natriuretic peptide in patients with non-ST-segment elevation acute coronary syndromes:A Fragmin and fast Revascularisation during In Stability in coronary artery disease(FRISC)-Ⅱ substudy显示文摘Lindahl B Lindback J Tomas J 0,,:1
17The effect of gamma irradiation on the quality of apheresis platelets during storage for 7 days显示文摘Tynngard Studer M Lindahl TL 0,,08:1
18Microstructure of model cermets with high Mo or W content显示文摘Lindahl P Gustafson P Rolander U 1999Int J Refract Metals Hard Mater1999,17,6:1
19Segond fracture combined with tibial plateau fracture 显示文摘Peltola EK Mustonen AO Lindahl J et a/ 2011AJR Am J ~Roentgenol2011,197,6:1
20Souble CD40L levels are regulated by the-3459 A > G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST-elevation acute coronary syndrome 显示文摘Malarstig A Lindahl B Wanentin L 2006Arterioscler Thromb Vasc Biol2006,26,:1
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