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| 1 | Experimental research on air film formation behavior of air cushion belt conveyor with stable load显示文摘In this paper, the air film formation behavior of air cushion belt conveyor with stable load is studied. The air cushion field is analyzed by means of theoretical derivation, numerical simulation and experimental research. An intelligent experiment platform is developed. Three dimensional pressure distribution of air film and the air film thickness distribution along the conveyor belt in the width direction are obtained. The experimental result is analyzed by comparing with theoretical calculation and numerical simulation. The numerical and theoretical results are in good agreement with those obtained from experiments. The air film formation behavior pattern of air cushion belt conveyor with stable load is presented. The optimized film thickness and pore distribution are obtained based on the comprehensive energy consumption. This study provides a basis for the optimization design of air cushion belt conveyor. | GUO Sheng LIU Jian LI ZhiRen ZHANG DongLi HUANG Wei | 2013 | Science China(Technological Sciences)2013，56，6： | 4 |
| 2 | Preparation and characterization of porous titania-grafted poly(styrene-divinylbenzene)/maleic anhydride nanocomposite microspheres显示文摘Mesoporous titania-grafted poly(styrene-divinylbenzene)/maleic anhydride [P(St-DVB)/MA] nanocomposite microspheres were prepared by an open ring reaction method.The titania nanoparticles were first modified by attachment of amino groups to their surface to prevent particle aggregation,and to allow the nanoparticles to covalently bond the polymer microspheres,the surface of which was modified by attachment of MA functional groups to enable the polymer to retain their porous structures and to react with the amino groups on the surface of the titania particles.The porous nanocomposite microspheres were detected by FTIR,SEM,TEM,XRD and UV-Vis spectrophotometry.The results indicated that the nanocomposite microspheres were composed of nanosized titania uniformly distributed on the surface,and exhibited better UV absorbing property than pure polymer microspheres or unmodified titania.Furthermore,compared with pure porous polymer microspheres,the nanocomposite microspheres showed more efficient UV protection and slow release of Parsol-1789(a photo-reactive and cosmetic agent) held inside the porous network of the microspheres. | Li Sen Wang Kuan Zhang ZhiRen Song ChunLian Cheng Jiang Yang ZhuoRu Wen XiuFang Pi PiHui | 2010 | Science China Chemistry2010，53，3： | 3 |
| 3 | Apoptosis induced by titanium dioxide nanoparticles in cultured murine microglia N9 cells显示文摘Owing to the rapidly increasing output of nano-scale titanium dioxide(TiO2) particles,their potential risk for central nerve system(CNS) has elicited much concern recently.Microglia is the resident macrophage in CNS and essential for the homeostasis of the CNS microenvironment.They are supposed to response to nanoparticles depositing in the brain tissues.Therefore,we investigated the cytotoxic effects of TiO2 NPs on microglia N9 cells in vitro.Results of propidium iodide/fluorescein diacetate(PI/FDA) double staining and MTT test clearly showed that TiO2 NPs more efficiently affected the viability of microglia N9 cells.Further Hoechst 33258 staining and flow cytometric analysis proved that nano-scale but not normal scale TiO2 induced apoptosis in vitro.These data suggest that TiO2 NPs can elicit apoptosis of N9 cells in vitro and thus present a potential risk for CNS. | LI XiaoBo XU ShunQing ZHANG ZhiRen Hermann J Schluesener | 2009 | Chinese Science Bulletin2009，54，20： | 2 |
| 4 | Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons显示文摘 | Ruidong Ye Nanlin Li Junliang Han Xiangwei Kong Rong Cao Zhiren Rao Gang Zhao | 2009 | Neuroscience Research2009，，3： | 1 |
| 5 | Preparation and evaluation of nano-hydroxyapatite/poly(styrene-divinylbenzene) porous microsphere for aspirin carrier显示文摘A novel vehicle for the delivery of aspirin (ASA) was prepared from porous nano-hydroxyapatite/poly(styrene-divinylbenzene) [nano-HAP/P(St-DVB)] composite microspheres by grafting nano-HAP [Ca10(PO4)6(OH)2] onto porous P(St-DVB) microspheres. Four types of porous composite microspheres were prepared, each with different nano-HAP contents. The ASA-loaded composite microspheres prepared with 10% and 15% nano-HAP (mass ratio) exhibited excellent buoyancy with relatively short instantaneous floating time (within 10 min) and a long sustained floating time (12 h) in simulated gastric juice. They also offered good sustained release of ASA (up to 8 h). Furthermore, these composite microspheres displayed good buffering capacity that prevented the buildup of acidity caused by hydrolysis of ASA, keeping the pH of gastric juice within the normal range (pH 0.9 to 1.5). The results showed that porous nano-HAP/P(St-DVB) composite microspheres prepared with 10% and 15% nano-HAP could be used as a novel drug carrier for ASA, providing a sustained release dose without leading to stomach irritation, a side effect that is often associated with ASA medication. | LI Sen WANG Kuan CHANG Kue-Chieh Alan ZONG Ming WANG Jing CAO YongGang BAI YuHua WEI TaiMing ZHANG ZhiRen | 2012 | Science China Chemistry2012，55，6： | 1 |
| 6 | Liver resection versus liver transplantation for hepatocellular carcinoma within the Milan criteria based on estimated microvascular invasion risks显示文摘Background:Preoperative prediction of microvascular invasion(MVI)in hepatocellular carcinoma(HCC)may optimize individualized treatment decision-making.This study aimed to investigate the prognostic differences between HCC patients undergoing liver resection(LR)and liver transplantation(LT)based on predicted MVI risks.Methods:We analysed 905 patients who underwent LR,including 524 who underwent anatomical resection(AR)and 117 who underwent LT for HCC within the Milan criteria using propensity score matching.A nomogram model was used to predict preoperative MVI risk.Results:The concordance indices of the nomogram for predicting MVI were 0.809 and 0.838 in patients undergoing LR and LT,respectively.Based on an optimal cut-off value of 200 points,the nomogram defined patients as high-or low-risk MVI groups.LT resulted in a lower 5-year recurrence rate and higher 5-year overall survival(OS)rate than LR among the high-risk patients(23.6%vs 73.2%,P<0.001;87.8%vs 48.1%,P<0.001)and low-risk patients(19.0%vs 45.7%,P<0.001;86.5%vs 70.0%,P=0.002).The hazard ratios(HRs)of LT vs LR for recurrence and OS were 0.18(95%confidence interval[CI],0.09–0.37)and 0.12(95%CI,0.04–0.37)among the high-risk patients and 0.37(95%CI,0.21–0.66)and 0.36(95%CI,0.17–0.78)among the low-risk patients.LT also provided a lower 5-year recurrence rate and higher 5-year OS rate than AR among the high-risk patients(24.8%vs 63.5%,P=0.001;86.7%vs 65.7%,P=0.004),with HRs of LT vs AR for recurrence and OS being 0.24(95%CI,0.11–0.53)and 0.17(95%CI,0.06–0.52),respectively.The 5-year recurrence and OS rates between patients undergoing LT and AR were not significantly different in the low-risk patients(19.4%vs 28.3%,P=0.129;85.7%vs 77.8%,P=0.161).Conclusions:LT was superior to LR for patients with HCC within the Milan criteria with a predicted high or low risk of MVI.No significant differences in prognosis were found between LT and AR in patients with a low risk of MVI. | Pinghua Yang Fei Teng Shilei Bai Yong Xia Zhihao Xie Zhangjun Cheng Jun Li Zhengqing Lei Kui Wang Baohua Zhang Tian Yang Xuying Wan Hao Yin Hao Shen Timothy M Pawlik Wan Yee Lau Zhiren Fu Feng Shen | 2023 | Gastroenterology Report2023，11，1： | 1 |
| 7 | Hydrothermal synthesis of Znl-xNixO room temperature DMS 显示文摘 | WEI Zhiren LI Jun LIU Chao | 2006 | J Synth Cryst (in Chinese)2006，35，： | 1 |
| 8 | Faber Polynomial Coefficient Estimates on a Subclass of Bi-Univalent Functions显示文摘The main objective of this paper is to derive the upper bounds for the coefficients of functions in a subclass of analytic and bi-univalent functions associated with Faber polynomials.The consequences presented here point out and correct the errors of some earlier results. | Xiaoyuan WANG Zhiren WANG Li YIN | 2018 | Journal of Mathematical Research with Applications2018，38，5： | 1 |
| 9 | Measurement of gear tooth dynamic deformation using dynamic speckle photography显示文摘A new method of measuring gear tooth dynamic deformation is proposed. Dynamic speckle photographs of the rotating gear tooth have been achieved by combining the pulsed ruby laser with the out-syn-signal. Double speckle patterns of the whole mesh period of gear tooth are obtained by accurate time delay of the ruby laser. Gear tooth dynamic deformation of the whole mesh period is achieved using the automatic image processing. Testing results show that the trends of gear tooth deformation coincides with the calculation by the finite element method. The success of this new trying provides a new technique for the measurement of gear tooth dynamic deformation. | Jianfeng Li Xing Ai Zhiren Tian | 1998 | Chinese Science Bulletin1998，43，6： | 0 |
| 10 | Modified Technique of Orthotopic Liver Transplantation in Rats显示文摘 | Xiaomin Shi Yongzhao Shi Zhiren Fu Xianxing Li Guoshan Ding Hong Fu | 2008 | 器官移植内科学杂志2008，3，1： | 0 |
| 11 | Antioxidant and Hypoglycemic Ability of Ardisia gigantifolia Stapf Parts显示文摘[Objectives]To study the antioxidant and hypoglycemic effects of different parts of Ardisia gigantifolia Stapf.[Methods]The hydroxyl radical scavenging activity,DPPH radical scavenging activity and total antioxidant capacity of ABTS of 75%ethanol extract of A.gigantifolia Stapf and the petroleum ether,ethyl acetate,n-butanol,chloroform and aqueous extract were measured with Vc as positive control.At the same time,acarbose was used as reference substance to determine the inhibitory effect of each polar site onα-glucosidase.[Results]All parts of A.gigantifolia Stapf had antioxidant activity,among which ethyl acetate had the strongest antioxidant activity,and the scavenging rate of hydroxyl radical and DPPH radical was higher than that of positive control.The results showed that petroleum ether,ethyl acetate and chloroform had a good inhibitory effect onα-glucosidase(better than acarbose).[Conclusions]The ethyl acetate part of A.gigantifolia Stapf had the best antioxidant activity and inhibitory effect onα-glucosidase.It provides a basis for further research and development of A.gigantifolia Stapf. | Chaohao GU Shihao LIANG Yuexuan WU Zhiren YAO Jiaojiao LI Kaimei ZHU | 2024 | Medicinal Plant2024，15，1： | 0 |
| 12 | Picking Out Meat from Crab's Legs──The Jiangsu Oilfield 显示文摘PickingOutMeatfromCrab'sLegs──TheJiangsuOilfield(Tryingtosqueezeonelastbonanzafromapatchofsoilthat'salreadyteenverykindtoChin... | LI CHEYING & WANG ZHIREN | 1996 | China Today1996，45，10： | 0 |
| 13 | m^(6)A mRNA modification potentiates Th17 functions to inflame autoimmunity显示文摘N6-methyladenosine(m^(6)A),the most common and abundant epigenetic RNA modification,governs mRNA metabolism to determine cell differentiation,proliferation and response to stimulation.m^(6)A methyltransferase METTL3 has been reported to control T cell homeostasis and sustain the suppressive function of regulatory T cells(Tregs).However,the role of m^(6)A methyltransferase in other subtypes of T cells remains unknown.T helper cells 17(Th17)play a pivotal role in host defense and autoimmunity.Here,we found that the loss of METTL3 in T cells caused serious defect of Th17 cell differentiation,and impeded the development of experimental autoimmune encephalomyelitis(EAE).We generated Mettl3f/fIl17aCre mice and observed that METTL3 deficiency in Th17 cells significantly suppressed the development of EAE and displayed less Th17 cell infiltration into central nervous system(CNS).Importantly,we demonstrated that depletion of METTL3 attenuated IL-17A and CCR5 expression by facilitating SOCS3 mRNA stability in Th17 cells,leading to disrupted Th17 cell differentiation and infiltration,and eventually attenuating the process of EAE.Collectively,our results highlight that m^(6)A modification sustains Th17 cell function,which provides new insights into the regulatory network of Th17 cells,and also implies a potential therapeutic target for Th17 cell mediated autoimmune disease. | Xuefei Wang Chen Chen Hongwei Sun Kaiqiong Mao Jiameng Yao Weiqiao Zhang Meixiao Zhan Hua-Bing Li Zhiren Zhang Shu Zhu Ligong Lu | 2023 | Science China(Life Sciences)2023，66，11： | 0 |
| 14 | Optical-field-induced Freeder-icksz transition of a nematic liquid crystal doped with dia-zophenyl显示文摘4[4’-(phenylazo)phenylazo]phenol was synthesized and characterized. Optical-induced Freedericksz transition of 5CB liquid crystal doped with trace diazophenyl was studied. It was observed that the doped 5CB dramatically decreased the optical field threshold, and the Freedericksz transition threshold occurred at optical intensity level of 0.3 mW/mm2 for the 12.5 μm thickness planar alignment doped 5CB, which is three orders of magnitude lower than that for the pure 5CB. This new phenomenon indicated that trans-cis isomerization of diazophenyl plays an important role in the decrease of the Freedericksz transition threshold. | WANG Jian LI Yu CHEN Yonglie LIANG Zhaoxi XIANG Ying LIN Ziyang SHI Longpei QIU Zhiren | 2001 | Chinese Science Bulletin2001，46，8： | 0 |
| 15 | Macrophage Dicer promotes tolerogenic apoptotic cell clearance and immune tolerance by inhibiting pentose phosphate pathway activity显示文摘Given that apoptosis is the dominant modality of homeostatic cell turnover,efficient clearance of apoptotic cells(ACs),which is a process known as efferocytosis,is critical for immune homeostasis.The phagocytic engulfment of ACs occurs through an immunologically silent process to prevent an immune response to self-antigens.Correspondingly,defects in the removal of ACs have been proposed to underlie the pathogenesis of systemic lupus erythematosus(SLE).1,2 However,pathways that regulate phagocytes for efficient immune-silent AC uptake remain to be fully elucidated.Dicer is best known for its role as a riboendonuclease in the biogenesis of microRNAs.3 While recent studies have determined a link between microRNAs and AC clearance,the interplay between Dicer and efferocytosis remains unknown. | Qiangdongzi Mao Bangwei Luo Jie Mei Wenhua Li Xue Zhang Zhiyu Wang Jiechun Zhang Tingting Liu Fengxue Zhang Zhiren Zhang | 2021 | Cellular & Molecular Immunology2021，18，7： | 0 |
| 16 | Effect of Mn Doping ZnO on Morphology and Magnetism Synthesized by Hydrothermal Method显示文摘The diluted magnetic semiconductor Zn1-xMnxO crystals were synthesized at 430 ℃ for 24 h by hydrothermal method. The mineralizer is 3 mol·L-1 KOH, and fill factor is 35%. The Mn concentration in crystal was determined by electron probe. The atomic percentage of Mn in crystal increases as the concentration of MnCl2·6H2O in precursor increases. The maximum of the Mn concentration in crystal is above 8%. The morphology of the crystal varies with the concentration of MnCl2·6H2O in precursor increases. And they all show the hexagonal feature of ZnO wurtzite. The measurement of magnetism was carried out by using a superconducting quantum interference device (SQUID). The crystals show low-temperature ferromagnetism with Curie temperature of 50 K. | Wei Zhiren Liu Chao Li Jun Ge Shiyan Lin Lin Zhang Huawei Dong Guoyi | 2006 | Journal of Rare Earths2006，24，z1： | 0 |
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