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| 1 | In situ boron isotope measurements of natural geological materials by LA-MC-ICP-MS显示文摘There are two main methods to determine boron isotopic composition.One is the solution method,in which boron is purified after the samples are dissolved in solution and the boron isotope ratios are determined by thermal ionization mass spectrometry(P-TIMS and N-TIMS) or multicollector inductively coupled plasma mass spectrometry(MC-ICP-MS).The other is an in-situ analysis method,in which the in-situ boron isotopic ratios in minerals are analyzed directly using secondary ion mass spectrometry(SIMS) or laser ablation multicollector inductively coupled plasma mass spectrometry(LA-MC-ICP-MS).In the in-situ analysis method for boron isotopes,the multifarious chemical purification and separation processes of the solution method are avoided,with increased work efficiency.In addition,the microzones and microbeddings of minerals can be analyzed in-situ to reveal the fine processes and conditions of mineral formation.In this study,using the standard-sample-bracketing(SSB) method,mass bias of the instrument and the fractionation of isotopes were calibrated,and the in-situ determination method of LA-MC-ICP-MS for boron isotopes was established.Through detailed analyses on a series of boron isotope standards and samples,a matrix effect was assessed but not detected,and the analysis results were in accordance with the formerly reported values or P-TIMS determined values,within the error range.The analytical results for IAEA B4 and IMR RB1 with relatively high boron contents were δ 11B =-(8.36±0.58)‰(2σ,n=50) and δ 11B =-(12.96±0.97)‰(2σ,n=57),respectively;the analytical result for IAEA B6 with rela-tively low boron content was δ 11B =-(3.29±1.12)‰(2σ,n=35).In-situ measurements for B isotopes were performed on geo-logical samples such as tourmaline,ulexite,ludwigite,inyoite and ascharite,with the results consistent with those determined by P-TIMS,within the error range. | HOU KeJun LI YanHe XIAO YingKai LIU Feng TIAN YouRong | 2010 | Chinese Science Bulletin2010，55，29： | 13 |
| 2 | Helium Isotope Geochemistry of Ultrahigh-Pressure Metamorphic Eclogites From the Dabie-Sulu Terrane in East China显示文摘The 3He/4He ratios of most eclogites from the Dabie-Sulu terrane range from 0.056 to 0.67 Ra; the data points fall into the mixing part of the crust and the mantle in the 3He-4He diagram. The 3He/4He ratios of eclogites are obviously correlated with the types of their surrounding rocks. The helium isotope composition of the eclogites from the Bixiling complex possesses characters of mantle-derived rocks with the 3He/4He ratio being 5.6 Ra. The 4He concentration of the eclogites exhibits visible inverse correlation with the δ18O value of the quartz in the eclogites from the Sulu area. The δ18O values of the eclogites change synchronously with those of the country rocks. Those results suggest that protoliths of the eclogites were basic-ultrabasic rock bodies or veins intruding into the continental crust in the early stage; strong exchange and hybridization between the basic-ultrabasic rocks and continental rocks and the atmospheric water during the intrusion led to abrupt increase of the 3He/4He ratios, | LI Yanhe LI Jincheng SONG Hebin LIU Xiaochun | 2000 | Acta Geologica Sinica(English Edition)2000，74，1： | 12 |
| 3 | Late Mesozoic Ore-forming Events in the Ningwu Ore District, Middle-Lower Yangtze River Polymetallic Ore Belt, East China: Evidence from Zircon U-Pb Geochronology and Hf Isotopic Compositions of the Granodioritic Stocks显示文摘Late Mesozoic volcanic-subvolcanic rocks and related iron deposits, known as porphyry iron deposits in China, are widespread in the Ningwu ore district (Cretaceous basin) of the middle-lower Yangtze River polymetallic ore belt, East China. Two types of Late Mesozoic magmatic rocks are exposed: one is dioritic rocks closely related to iron mineralization as the hosted rock, and the other one is granodioritic (-granitic) rocks that cut the ore bodies. To understand the age of the iron mineralization and the ore-forming event, detailed zircon U-Pb dating and Hf isotope measurement were performed on granodioritic stocks in the Washan, Gaocun-Nanshan, Dongshan and Heshangqiao iron deposits in the basin. Four emplacement and crystallization (typically for zircons) ages of granodioritic rocks were measured as 126.1±0.5 Ma, 126.8±0.5 Ma, 127.3±0.5 Ma and 126.3±0.4 Ma, respectively in these four deposits, with the LA-MC-ICP-MS zircon U-Pb method. Based on the above results combined with previous dating, it is inferred that the iron deposits in the Ningwu Cretaceous basin occurred in a very short period of 131-127 Ma. In situ zircon Hf compositions of εHf(t) of the granodiorite are mainly from -3 to -8 and their corresponding 176Hf/177Hf ratio are from 0.28245 to 0.28265, indicating similar characteristics of dioritic rocks in the basin. We infer that granodioritic rocks occurring in the Ningwu ore district have an original relationship with dioritic rocks. These new results provide significant evidence for further study of this ore district so as to understand the ore-forming event in the study area. | DUAN Chao LI Yanhe HOU Kejun YUAN Shunda LIU Jialin ZHANG Cheng | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 11 |
| 4 | Sedimentary Characteristics and Paleoenvironmental Records of Zabuye Salt Lake,Tibetan Plateau,since 128 ka BP显示文摘This paper for the first time reveals high-resolution core records of Zabuye Salt Lake in the interior of the Qinghai-Tibet Plateau.According to 1346 samples taken continuously,relatively accurate ^(14)C,U-series disequilibrium and ESR ages have been obtained,thus revealing that the lake core ages from 0 to 83.63m of hole SZK02 are~800 to over 128 ka.In the paper,the lake core sedimentary characteristics(including the lithologies and mineral assemblages)are analyzed in detail and correlated with ostracod assemblages I to XX and sporopollen zones A to I,and on the basis of an integrated analysis of theδ^(18)0 values of authigenic calcium-magnesium carbonate and environmental proxies of minerals,sporopollen and microfossils in the lake core,a correlation has been made of oxygen isotope change between this lake core and the Greenland GISP2 and GRIP and Guliya ice cores,and the climate of Zabuye Salt Lake since 128 ka BP is divided into the last interglacial stage (including substages e,d,c,b and a)of oxygen isotope stage(OIS)5,early glacial stadial of the last glacial stage of OIS 4,interglacial stadial of the last glacial stage of OIS 3,late glacial stadial of the last glacial stage or Last Glacial Maximum of OIS 2 and postglacial state of OIS 1;in addition,6 Heinrich (H_6-H_1)events,Younger Dryas event and 8.2 ka BP cold event have been recognized. | ZHENG Mianping YUAN Heran LIU Junying LI Yanhe MA Zhibang SUN Qing | 2007 | Acta Geologica Sinica(English Edition)2007，81，5： | 10 |
| 5 | Separation and Precise Measurement of Lithium Isotopes in Three Reference Materials Using Multi Collector-Inductively Coupled Plasma Mass Spectrometry显示文摘Lithium separation technique for three reference materials has been established together with precise determination of lithium isotope using a Neptune multi collector-inductively coupled plasma mass spectrometry (MC-ICP-MS). The solutions of lithium element standard reference materials, potassium, calcium, sodium, magnesium and iron single element, were used to evaluate analytical methods applied. Three separate stages of ion-exchange chromatography were carried out using organic cation-exchange resin (AG 50W-X8). Lithium was enriched for the three stages using different eluants, which are 2.8 M HCl, 0.15 M HCl and 0.5 M HCl in 30% ethanol, respectively. The columns for the first and second stages are made of polypropylene, and those for the third stage are made of quartz. Total reagent volume for the entire chemical process was 35 mL for three reference materials. The recovery yielded for the three stages is 98.9-101.2% with an average of 100.0%, 97.6- 101.9% with an average of 99.9%, and 99.8-103.3% with an average of 100.6%, respectively. The precision of this technique is conservatively estimated to be ±0.72-1.04‰ (2σ population), which is similar to the precision obtained by different authors in different laboratories with MC-ICP-MS. The δ 7 Li values ( 7 Li/ 6 Li relative to the IRMM-016 standard) determined for andesite (AGV-2) and basalt (BHVO-2) are 5.68‰ (n=18), 4.33‰ (n=18), respectively. The δ 7 Li value ( 7 Li/ 6 Li relative to the L-SVEC standard) determined for IRMM-016 is -0.01‰ (n=15). All these analytical results are in good agreement with those previously reported. In addition, the results for the same kinds of samples analyzed at the MLR Key Laboratory of Metallogeny and Mineral Assessment, Institute of Mineral Resources, Chinese Academy of Geological Sciences, are consistent with those obtained at the Plasma Laboratory, University of Maryland, within analytical uncertainty. According to these experiment results, it is concluded that this proposed procedure is a suitable method for determining the lithium isotopic composition of natural samples. | TIAN Shihong HOU Zengqian SU Aina HOU Kejun HU Wenjie LI Zhenzhen ZHAO Yue GAO Yanguang LI Yanhe YANG Dan YANG Zhusen | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 9 |
| 6 | S, C, O, H Isotope Data and Noble Gas Studies of the Maoniuping LREE Deposit, Sichuan Province, China: A Mantle Connection for Mineralization显示文摘Maoniuping REE 存款,定位了大约 22 km 到 Mlanning 的西南,四川省,是在中国的第二最大的轻 REE 存款,对 Bayan OboFe-Nfo-REE 存款 inihe 随后内部蒙古自治区域。构造地,它位于在 Panxi 裂缝之间的过渡地区和 Longmenshan-Jinpingshan orogenic 地区。它是在碱的复合岩石招待的 acarbonatite 静脉类型沉积物。bastnaesite 重晶石, bastnaesite 方解石,和 bastnaesite-microcline 矿脉是主要 REE 矿石矿脉的三种类型。在这些之中,第一条矿脉最广泛地被散布,它的 REE 矿化作用最强壮。在存款的矿石的 barltes 的 DELTA^(34 )S_(V-CDT ) 价值每千条 Inthe bastnaesite 重晶石矿脉在 bastnaesite 方解石矿脉和 +33 每千在 +5.0 的一个狭窄的范围变化到 +5.1 到 +5.9,显示出导出岩浆的硫的同位素的特征。分别地,O_(V降雪)在bastnaesite方解石矿脉珍视的TheDELTA^( 13 )C_( V-PDB )价值和DLETA^( 18 )每千每千并且从 +7.3 从 -3.9 到 -6.9 到 +9.7 它掉进“主要 carbonatites ”的范围,在 Maoniupingdeposit 的矿石显示出那碳和氧主要从深来源被导出。液包体的 DELTA^(13 )C_(V-PDB ) 价值每千从 -3.0 变化到 -5.6,与到在 bastnaesite 方解石矿脉的每千的 -4.0 的 -3.0 和到在 bastnaesite 重晶石矿脉的每千的 -5.6 的 -3.0,它显示出特征导出 ofmantle 的碳。detla^(18O_((H_2OV ) 液包体的 -SMOW)) 价值每千从 -57 to-88 ,与到 -86 的 -63 每千在到 -88 的 bastnaesite 方解石矿脉和 -57 每千在 bastnaesite 重晶石矿脉,它导出披风的氢的表演特征。TheDELTA^(18 )O_(H_2OV 降雪) 价值每千从 +7.4 变化到 +8.6 在。bastnaesite-calcitelode,和 +6.7 到 +7.8 每千在 bastnaesite 重晶石矿脉,几乎重叠范围 of+5.5 到 +9.5 每千为 magmatic。~ 4He 内容, R/Ra 比率是(13.95 to119.58 )X10^(-6)(cm^3/g )_(STP ) 并且 0.02 ~ 0.11,分别地并且 ^(40 )Ar/^(36 ) Ar 是 313 +- 1 to437 +- 2。就放射性元素的高内容引起的 4He 增加而言,导出 amantle 的液体可能在 fluorlte,方解石和 bastnaesitesamples 在包括存在。Maoniuping 存款和它的联系 carbonatite 碱的建筑群在 40.3to 被形成 12.2 妈根据 K-Ar 和 U-Pb 数据。所有这些数据建议披风液体的大数量通过一个差错系统涉及 Maoniuping REE 存款的 metallogenic 进程。 | TIAN Shihong DING Tiping MAO Jingwen LI Yanhe YUAN Zhongxin | 2006 | Acta Geologica Sinica(English Edition)2006，80，4： | 6 |
| 7 | Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the paclitaxel biosynthetic pathway显示文摘Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assembling a chromosome-level genome of the Himalayan yew(Taxus wallichiana)with 10.9 Gb in 12 chromosomes,we revealed that tandem duplication acts as the driving force of gene family evolution in the yew genome,resulting in the main genes for paclitaxel biosynthesis,i.e.those encoding the taxadiene synthase,P450s,and transferases,being clustered on the same chromosome.The tandem duplication may also provide genetic resources for the nature to sculpt the core structure of taxoids at different positions and subsequently establish the complex pathway of paclitaxel by neofunctionalization.Furthermore,we confirmed that there are two genes in the cluster encoding isoenzymes of a known enzyme in the paclitaxel biosynthetic pathway.The reference genome of the Himalayan yew will serve as a platform for decoding the complete biosynthetic pathway of paclitaxel and understanding the chemodi-versity of taxoids in gymnosperms. | Jian Cheng Xiao Wang Xiaonan Liu Xiaoxi Zhu Zihe Li Huanyu Chu Qian Wang QianQian Lou Bijun Cai Yiqun Yang Xiaoyun Lu Kai Peng Dingyu Liu Yuwan Liu Lina Lu Huan Liu Ting Yang Qijin Ge Chengcheng Shi Guichun Liu Zhiwei Dong Xun Xu Wen Wang Huifeng Jiang Yanhe Ma | 2021 | Molecular Plant2021，14，7： | 6 |
| 8 | Occurrence of the Iron–rich Melt in the Heijianshan Iron Deposit, Eastern Tianshan, NW China: Insights into the Origin of Volcanic Rock–hosted Iron Deposits显示文摘Long-standing controversy persists over the presence and role of iron–rich melts in the formation of volcanic rock-hosted iron deposits. Conjugate iron–rich and silica–rich melt inclusions observed in thin-sections are considered as direct evidence for the presence of iron-rich melt, yet unequivocal outcrop-scale evidence of iron-rich melts are still lacking in volcanic rock-hosted iron deposits. Submarine volcanic rock-hosted iron deposits, which are mainly distributed in the western and eastern Tianshan Mountains in Xinjiang, are important resources of iron ores in China, but it remains unclear whether iron-rich melts have played a role in the mineralization of such iron ores. In this study, we observed abundant iron-rich agglomerates in the brecciated andesite lava of the Heijianshan submarine volcanic rock–hosted iron deposit, Eastern Tianshan, China. The iron-rich agglomerates occur as irregular and angular masses filling fractures of the host brecciated andesite lava. They show concentric potassic alteration with silicification or epidotization rims, indicative of their formation after the wall rocks. The iron-rich agglomerates have porphyritic and hyalopilitic textures, and locally display chilled margins in the contact zone with the host rocks. These features cannot be explained by hydrothermal replacement of wall rocks(brecciated andesite lava) which is free of vesicle and amygdale, rather they indicate direct crystallization of the iron-rich agglomerates from iron-rich melts. We propose that the iron-rich agglomerates were formed by open-space filling of volatile-rich iron-rich melt in fractures of the brecciated andesite lava. The iron-rich agglomerates are compositionally similar to the wall-rock brecciated andesite lava, but have much larger variation. Based on mineral assemblages, the iron-rich agglomerates are subdivided into five types, i.e., albite-magnetite type, albite-K-feldsparmagnetite type, K-feldspar–magnetite type, epidote-magnetite type and quartz-magnetite type, representing that products formed at different stages during the evolution of a magmatic-hydrothermal system. The albite-magnetite type represents the earliest crystallization product from a residual ironrich melt; the albite-K-feldspar-magnetite and K-feldspar-magnetite types show features of magmatichydrothermal transition, whereas the epidote-magnetite and quartz-magnetite types represent products of hydrothermal alteration. The occurrence of iron-rich agglomerates provides macroscopic evidence for the presence of iron-rich melts in the mineralization of the Heijianshan iron deposit. It also indicates that iron mineralization of submarine volcanic rock-hosted iron deposits is genetically related to hydrothermal fluids derived from iron-rich melts. | LI Houmin LI Lixing DING Jianhua LI Yanhe SONG Zhe MENG Jie MA Yubo | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 5 |
| 9 | Discovery of Mass Independent Oxygen Isotopic Compositions in Superscale Nitrate Mineral Deposits from Turpan-Hami Basin,Xinjiang,China and Its Significance显示文摘在东方 Xinjiang 的 Turpan-Hami 盆是在地球上的最干燥的区域和首要的环境之一形成并且保存硝酸盐。在这盆的大硝酸盐矿石域最近被发现。它在那里被估计是硝酸盐的大约 25 亿个大量资源,并且数量像在智利的 Atacama 荒芜的超级规模的硝酸盐沉积物一样。硝酸盐是有团无关的分别(MIF ) 的一些矿物质之一,并且氧同位素 MIF 是一个有效方法决定硝酸盐的来源。17O,硝酸盐的 18O 被氟化作用和热分解方法测量。日期显示这是氧同位素 MIF 位于内陆硝酸盐矿物质的第一次。结果由二个方法获得了是类似的, 17O=17O0.52 映杯吗? | LI Yanhe QIN Yan LIU Feng HOU Kejun WAN Defang | 2010 | Acta Geologica Sinica(English Edition)2010，84，6： | 5 |
| 10 | N and O isotopes and the ore-forming mechanism of nitrate deposits in the Turpan-Hami Basin,Xinjiang,China显示文摘The recently discovered nitrate ore field in the Turpan-Hami Basin of western China represents an estimated resource of 2.5 billion tons, and is comparable in scale to the Atacama Desert super-scale nitrate deposit in Chile. The research on this area is rarely carried out, and the origin of the deposits remains uncertain. In this study, new methods were used to systematically analyze N and O isotopes in nitrate minerals collected from the Kumutage, Xiaocaohu, Wuzongbulak, Dawadi, Tuyugou, and Shaer ore deposits in the Turpan-Hami Basin. The data showed that the δ15NAir value ranges from 0.7‰ to 27.6‰, but mostly between 2‰ and 6‰, which was similar to atmospheric NO3-. The 18O was highly enriched with δ18OV-SMOW varying from 30.2‰ to 46.7‰. This differs from levels in deposits derived from microbial nitrogen fixation, but is similar to those in atmospheric nitrates. N and O isotopes data indicated that nitrate deposits in Turpan-Hami Basin must be the result of deposition of atmospheric nitrate particles. Although atmospheric nitrate particles are common, the nitrate deposits could form only under the condition of long-term extreme drought climate and very limited biological activity. This paper summarized the ore-forming mechanism of different types nitrate deposits based on their geological setting. | QIN Yan LI YanHe LIU Feng HOU KeJun WAN DeFang ZHANG Cheng | 2012 | Science China Earth Sciences2012，55，2： | 5 |
| 11 | Precise temporal regulation of Dux is important for embryo development显示文摘Dear Editor,Zygotic genome activation(ZGA)following fertilization is accomplished through a process termed the maternal-to-zygotic transition,during which the maternal RNAs and proteins are degraded and zygotic genome is transcriptionally activated.In mice,minor ZGA occurs from S phase of the zygote to G1 phase of the two-cell(2C)embryo,while major ZGA takes place during the middle-to-late 2C stage with a burst of transcription of totipotent cleavage stage-specific genes and retrotransposons. | Mingyue Guo Yanping Zhang Jianfeng Zhou Yan Bi Junqin Xu Ce Xu Xiaochen Kou Yanhong Zhao Yanhe Li Zhifen Tu Kuisheng Liu Jiaming Lin Peng Yang Shaorong Gao Yixuan Wang | 2019 | Cell Research2019，29，11： | 5 |
| 12 | Extreme Enrichment of Tellurium in Deep-Sea Sediments显示文摘Tellurium is a sort of scattered rare element on the earth. Its concentration is very low in earth’s crust, only 1.0 ng/g. However, it has extremely high abundance in Co-rich crusts, marine polymetallic nodules, deep-sea sediments and aerolites. To find out the origin of tellurium enrichment in deep-sea sediments, we analyzed and compared tellurium concentrations and helium isotope compositions in the magnetic parts and those in the bulk parts of deep-sea sediments. The result indicates that the helium content, 3He/4He ratio and tellurium concentration are obviously higher in the magnetic parts than those in the bulk parts. The 3He abundance varies synchronously with the tellurium concentration. 3He and Te have a distinct positive correlation with each other. It is the first time that the paper brings forward that the extreme enrichment of tellurium in deep-sea sediments, like helium isotope anomalies, probably results from the input of interplanetary dust particles (IDPs). Similarly, the extreme enrichment of tellurium in marine polymetallic nodules and Co-rich crusts is possibly related to IDPs. | LI Yanhe WANG Yimin SONG Hebin YUE Guoliang | 2005 | Acta Geologica Sinica(English Edition)2005，79，4： | 3 |
| 13 | The origin and evolution of the diosgenin biosynthetic pathway in yam显示文摘Diosgenin,mainly produced by Dioscorea species,is a traditional precursor of most hormonal drugs in the pharmaceutical industry.The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants remain unclear.After sequencing the whole genome of Dioscorea zingiberensis,we revealed the evolutionary trajectory of the diosgenin biosynthetic pathway in Dioscorea and demonstrated the de novo biosynthesis of diosgenin in a yeast cell factory.First,we found that P450 gene duplication and neofunctionalization,driven by positive selection,played important roles in the origin of the diosgenin biosynthetic pathway.Subsequently,we found that the enrichment of diosgenin in the yam lineage was regulated by CpG islands,which evolved to regulate gene expression in the diosgenin pathway and balance the carbon flux between the biosynthesis of diosgenin and starch.Finally,by integrating genes fromplants,animals,and yeast,weheterologously synthesized diosgenin to 10mg/l in genetically-engineered yeast.Our study not only reveals the origin and evolutionary mechanisms of the diosgenin biosynthetic pathway in Dioscorea,but also introduces an alternative approach for the production of diosgenin through synthetic biology. | Jian Cheng Jing Chen Xiaonan Liu Xiangchen Li Weixiong Zhang Zhubo Dai Lina Lu Xiang Zhou Jing Cai Xueli Zhang Huifeng Jiang Yanhe Ma | 2021 | Plant Communications2021，2，1： | 2 |
| 14 | Archean Mass-independent Fractionation of Sulfur Isotope:New Evidence of Bedded Sulfide Deposits in the Yanlingguan-Shihezhuang area of Xintai,Shandong Province显示文摘摘要:太古代的 bedded 硫化物存款的多重硫同位素比率(34S/33S/32S ) 在 Xintai 在泰山组的 Yanlingguan 形成被测量,山东省,中国的东方;33S =?0.7% ~ 3.8% , 34S =0.1%-8.8% , 33S =?2.3% 到 ?0.7% 。硫同位素作文显示出明显的团无关的分别(MIF ) 签名。在太古代的硫化物的硫同位素的 MIF 的存在显示硫从太阳的紫外放射导致的暴烈的 SO2 的光化学的反应的产品,暗示臭氧盾没在在那时间的空气被形成,并且氧水平是不到 10 ? 5 PAL (现在的空气水平)。SO2 的光分解作用与否定 33S 生产的硫酸盐在暴烈的活动中心附近猛抛;并且有积极 33S 的元素 S 的产品远猛抛离开暴烈的活动中心。硫化物的更低的 33S 价值(-2.30% 到 ?0.25%) Shihezhuang 在暴烈的中心附近,并且硫主要从硫酸盐的表演由光分解作用生产了。更高的 33S 价值(-0.5% 到 ?2%) 显示 Yanlingguan 是远的离开暴烈的中心并且一些硫从硫酸盐,从元素 S 的另外一个由光分解作用生产了。从 Yanlingguan 的硫同位素的数据点在 34S-33S 的阴谋上在到 MFL (集体依赖分别线) 的线平行,证明暴烈的硫种类通过了进海洋的大气的周期,然后集体依赖分别发生在硫化物的免职期间。从 Shihezhuang 的硫同位素的数据点代表不同的硫来源的混合。 | LI Yanhe HOU Kejun WAN Defang YUE Guoliang | 2008 | Acta Geologica Sinica(English Edition)2008，82，2： | 2 |
| 15 | Comparative proteome analysis of alkaliphilic Bacillus sp.N16-5 grown on different carbon sources显示文摘To determine the impact of carbohydrates on the metabolic pathway in alkaliphiles, proteomes were obtained from cultures containing different carbohydrates and were resolved on two-dimensional gel electrophoresis (2-DE). The proteomes were compared to determine differentially expressed proteins. A novel alkaliphilic bacterium (alkaliphilic Bacillus sp. N16-5 isolated from Wudunur Soda Lake, China) was isolated in media with five different carbon sources (glucose, mannose, galactose, arabinose, and xylose). Comparative proteome analysis identified 61 differentially expressed proteins, which were mainly involved in carbohydrate metabolism, amino acid transport, and metabolism, as well as energy production and conversion. The comparison was based on the draft genome sequence of strain N16-5. The abundance of enzymes involved in central metabolism was significantly changed when exposed to various carbohydrates. Notably, catabolite control protein A (CcpA) was up-regulated under all carbon sources compared with glucose. In addition, pentose exhibited a stronger effect than hexose in CcpA-mediated carbon catabolite repression. These results provided a fundamental understanding of carbohydrate metabolism in alkaliphiles. | LI Gang SONG YaJian XUE YanFen RAO Lang ZHOU Chen WANG QuanHui MA YanHe | 2011 | Science China(Life Sciences)2011，54，1： | 2 |
| 16 | Medium optimization by combination of response surface methodology and desirability function: an application in glutamine production显示文摘 | Jinshan Li Cuiqing Ma Yanhe Ma Yan Li Wei Zhou Ping Xu | 2007 | Applied Microbiology and Biotechnology2007，，3： | 1 |
| 17 | Monitoring the microbial community during solid-state acetic acid fermentation of Zhenjiang aromatic vinegar显示文摘 | Wei Xu Zhiyong Huang Xiaojun Zhang Qi Li Zhenming Lu Jinsong Shi Zhenghong Xu Yanhe Ma | 2011 | Food Microbiology2011，，6： | 1 |
| 18 | Extraterrestrial3 He in marine polymetallic nodules: A potential method for measuring growth rate of nodules显示文摘 | Yanhe Li Hebin Song Jincheng Li | 2002 | Science in China Series B: Chemistry2002，，1： | 1 |
| 19 | Overexpression of d -psicose 3-epimerase from Ruminococcus sp. in Escherichia coli and its potential application in d -psicose production显示文摘 | Yueming Zhu Yan Men Wei Bai Xiaobo Li Lili Zhang Yuanxia Sun Yanhe Ma | 2012 | Biotechnology Letters2012，，10： | 1 |
| 20 | Synthesis of mesoporous ZnO nanowires through a simple in situ precipitation method 显示文摘 | XIAO Yanhe LI Liang LI Yan | 2005 | Nanotechnology2005，16，6： | 1 |
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