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| 1 | Overexpression of SGR Results in Oxidative Stress and Lesion-mimic Cell Death in Rice Seedlings显示文摘It is thought that the Stay Green Rice(SGR)gene is involved in the disaggregation of the light harvesting complex and in the subsequent breakdown of chlorophyll and apo-protein during senescence.In this study,we found that overexpression of SGR(Ov-SGR)resulted in the generation of singlet oxygen and other reactive oxygen species and produced a chlorophyll-dependent regional cell death phenotype on leaves of rice seedlings.Transcriptome analyses using Affymetrix Rice GeneChips revealed that Ov-SGR rice seedlings exhibited a number of signs of singlet oxygen response.The genes and their associated biochemical pathways identified provide an insight into how rice plants respond to singlet oxygen at the molecular and physiologic level. | Huawu Jiang Yaping Chen Meiru Li Xingian Xu Guojiang Wu | 2011 | Journal of Integrative Plant Biology2011，53，5： | 16 |
| 2 | ζ-Carotene Isomerase Suppresses Tillering in Rice through the Coordinated Biosynthesis of Strigolactone and Abscisic Acid显示文摘Rice tillering is an important agronomic trait affecting grain yield.Here,we identified a high-tillering mutant tillering20(t20),which could be restored to the wild type by treatment with the strigolactone(SL)analog rac-GR24.T20 encodes a chloroplast ζ-carotene isomerase(Z-ISO),which is involved in the biosynthesis of ca-rotenoids and their metabolites,SL and abscisic acid(ABA).The t20 mutant has reduced SL and ABA,raising the question of how SL and ABA biosynthesis is coordinated,and whether they have overlapping functions in tillering.We discovered that rac-GR24 stimulated T20 expression and enhanced all-trans-p-carotene biosynthesis.Importantly,rac-GR24 also stimulated expression of Oryza sativa 9-CIS-EPOXY-CAROTENOID DIOXYGENASE 1(OsNCED1)through induction of Oryza sativa HOMEOBOX12(0sHOX12),promoting ABA biosynthesis in shoot base.On the other hand,ABA treatment significantly repressed SL biosynthesis and the ABA biosynthetic mutants displayed elevated SL biosynthesis.ABA treatment reduced the number of basal tillers in both t20 and wild-type plants.Furthermore,while ABA-deficient mu-tants aba1 and aba2 had the same number of basal tillers as wild type,they had more unproductive upper tillers at maturity.This work demonstrates complex interactions in the biosynthesis of carotenoid,SLs and ABA,and reveals a role for ABA in the regulation of rice tillering. | Xue Liu Qingliang Hu Jijun Yan Kai Sun Yan Liang Meiru Jia Xiangbing Meng Shuang Fang Yiqin Wang Yanhui Jing Guifu Liu Dianxing Wu Chengcai Chu Steven M.Smith Jinfang Chu Yonghong Wang Jiayang Li Bing Wang | 2020 | Molecular Plant2020，13，12： | 11 |
| 3 | CRISPR/Cas9-introduced single and multiple mutagenesis in strawberry显示文摘CRISPR/Cas9-mediated genome editing is a powerful tool for life science research.Recently,strawberry (Fragaria × ananassa),an important horticultural crop,has emerged as a model organism for investigating the regulatory mechanisms of fruit development and ripening (Shulaev et al.,2011;Jia et al.,2013,2017;Kang et al.,2013;Han et al.,2015).While most cultivated strawberries (e.g.,F.× ananassa)are octoploid,most wild strawberries (e.g.,F.vesca)are diploid.Although CRISPR/Cas9 methods have been established in many plants,the use of this tool in strawberry needs to be further explored (Zhou et al.,2018). | Sinian Xing Meiru Jia Lingzhi Wei Wenwen Mao Usman Ali Abbasi Yaoyao Zhao Yating Chen Minglin Cao Kai Zhang Zhengrong Dai Zhechao Dou Wensuo Jia Bingbing Li | 2018 | Journal of Genetics and Genomics2018，45，12： | 4 |
| 4 | Protein changes in rice seedlings during the enhancement of chilling resistance by different stress pretreatment显示文摘The changes of proteins in the rice (Oryza sativa L. ) Tesanai 2 seedling under salt ( NaCl ,4 g/L), heat shock (42℃, 3h), and cold(14℃, 3d) pretreatments were compared toexplore the mechanism of the cross adaptationto different environmental stresses. | ZENG Shaoxi ,WANG Yirou , and LI Meiru, South China Inst of Botany, China Acdemia, Guangzhou 510650, China | 1997 | Chinese Rice Research Newsletter1997，5，3： | 4 |
| 5 | Drought tolerance evaluation of tobacco plants transformed with different set of genes under laboratory and field conditions显示文摘尽管广泛的研究证明了许多干旱应答的基因授与干旱忍耐到植物,能力在各种各样的自然条件下面由不同基因授与的干旱忍耐的比较很少有报导。我们评估了并且比较 transgenes,干旱应答的基因(AtDREB1B 和 AtCBL1 ) 和根的二个集合的效果调整建筑学的基因(iaaM 和 AtCKX ) ,在在 Nicotiana tabacum 的干旱忍耐上,植物使遭到了到不同条件。根特定的倡导者 PYK10 驾驶的 AtCKX3 的表示(此后指定了为 P10;P10 : AtCKX3 ) , 35S:AtCKX3,或 P10:iaaM 支持了根生长和开发。比作怀有 P10 的植物: 展出的 AtCKX3, 35S:AtCKX3, P10:iaaM,或空向量,那些带的 35S:AtDREB1B, 35S:AtCBL1,或 35S:iaaM 在控制实验室的条件下面增加了干旱忍耐。相反地,在地里,条件,与 35S:AtDREB1 转变的植物, 35S:AtCBL1,或 35S:iaaM 对干旱应力敏感。在地条件下面,干旱应力戏剧性地减少了生长和而它在带 P10 的植物上有小效果,怀有 35S:AtDREB1B, 35S:AtCBL1, 35S:iaaM,或空向量的植物的种子生产: AtCKX3, 35S:AtCKX3,或 P10:iaaM。这研究证明到有环境条件的干旱压力变化的植物忍耐,和我们的结果显示操作控制根建筑学的基因的表示可能为处于自然条件与改进干旱忍耐设计植物是重要的。 | Yuanhua Wang Ruihong Dang Jinxi Li Yu Han Ning Ding Xingliang Li Meiru Jia Ziqiang Li Lingzhi Wei Jinzhu Jiang Yijuan Fan Bingbing Li Wensuo Jia | 2015 | Science Bulletin2015，60，6： | 3 |
| 6 | OsMPK4 promotes phosphorylation and degradation of IPA1 in response to salt stress to confer salt tolerance in rice显示文摘Salt stress adversely affects plant growth,development,and crop yield.Rice(Oryza sativa L.)is one of the most salt-sensitive cereal crops,especially at the early seedling stage.Mitogen-activated protein kinase(MAPK/MPK)cascades have been shown to play critical roles in salt response in Arabidopsis.However,the roles of the MPK cascade signaling in rice salt response and substrates of Os MPK remain largely unknown.Here,we report that the salt-induced Os MPK4-Ideal Plant Architecture 1(IPA1)signaling pathway regulates the salt tolerance in rice.Under salt stress,Os MPK4 could interact with IPA1 and phosphorylate IPA1 at Thr180,leading to degradation of IPA1.Genetic evidence shows that IPA1 is a negative regulator of salt tolerance in rice,whereas Os MPK4 promotes salt response in an IPA1-dependent manner.Taken together,our results uncover an Os MPK4-IPA1 signal cascade that modulates the salt stress response in rice and sheds new light on the breeding of salt-tolerant rice varieties. | Meiru Jia Nan Luo Xiangbing Meng Xiaoguang Song Yanhui Jing Liquan Kou Guifu Liu Xiahe Huang Yingchun Wang Jiayang Li Bing Wang Hong Yu | 2022 | Journal of Genetics and Genomics2022，49，8： | 2 |
| 7 | Genome-wide analysis of the WRKY gene family in physic nut ( Jatropha curcas L.)显示文摘 | Wangdan Xiong Xueqin Xu Lin Zhang Pingzhi Wu Yaping Chen Meiru Li Huawu Jiang Guojiang Wu | 2013 | Gene2013，，2： | 2 |
| 8 | Molecular cloning and function analysis of the stay green gene in rice 显示文摘 | JIANG H W LI MEIRU LIANG NAITING | 2007 | The Plant Journal2007，52，： | 1 |
| 9 | Static Expansion Vacuum Standard with Extended Low Pressure Range 显示文摘 | Li Detian Zhao Guangping Guo Meiru | 2009 | MAPAN-Joumal of Metrology Society of India2009，24，2： | 1 |
| 10 | Effects of Pressure Overload on Extracellular Matrix Expression in the Heart of the Atrial Natriuretic Peptide–Null Mouse显示文摘 | Dajun Wang Suzanne Oparil Ji An Feng Peng Li Gilbert Perry Lan Bo Chen Meiru Dai Simon W.M. John Yiu-Fai Chen | 2003 | Hypertension: Journal of the American Heart Association2003，，1： | 1 |
| 11 | Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma显示文摘Liver cancer is a prevalent malignant cancer,ranking third in terms of mortality rate.Metastasis and recurrence primarily contribute to the high mortality rate of liver cancer.Hepatocellular carcinoma(HCC)has low expression of focal adhesion kinase(FAK),which increases the risk of metastasis and recurrence.Nevertheless,the efficacy of FAK phosphorylation inhibitors is currently limited.Thus,investigating the mechanisms by which FAK affects HCC metastasis to develop targeted therapies for FAK may present a novel strategy to inhibit HCC metastasis.This study examined the correlation between FAK expression and the prognosis of HCC.Additionally,we explored the impact of FAK degradation on HCC metastasis through wound healing experiments,transwell invasion experiments,and a xenograft tumor model.The expression of proteins related to epithelial-mesenchymal transition(EMT)was measured to elucidate the underlying mechanisms.The results showed that FAK PROTAC can degrade FAK,inhibit the migration and invasion of HCC cells in vitro,and notably decrease the lung metastasis of HCC in vivo.Increased expression of E-cadherin and decreased expression of vimentin indicated that EMT was inhibited.Consequently,degradation of FAK through FAK PROTAC effectively suppressed liver cancer metastasis,holding significant clinical implications for treating liver cancer and developing innovative anti-neoplastic drugs. | XINFENG ZHANG SHUANG LI MEIRU SONG YUE CHEN LIANGZHENG CHANG ZHERUI LIU HONGYUAN DAI YUTAO WANG GANGQI YANG YUN JIANG YINYING LU | 2024 | Oncology Research2024，32，4： | 0 |
| 12 | Metabolic profile of chiral cobalt oxide nanoparticles in vitro and in vivo显示文摘In this study,we investigated the in vivo behaviors of chiral cobalt oxide nanoparticles(Co_(3)O_(4) NPs)stabilized with D-or L-cysteine(denoted D-or L-NPs,respectively),as representative chiral metal oxide NPs.Chiral Co_(3)O_(4) NPs exerted no observable cytotoxicity within the tested dose range.Both D-NPs and L-NPs were internalized by dendritic cells through caveola-dependent endocytosis,and L-NPs entered the cells faster than D-NPs.Significantly,a metabolic analysis indicated that chiral L-NPs had the same effect on the level of bile acids in the liver as D-NPs,which is attributed to the almost equal amount of farnesoid X receptor(FXR)induced by the chiral NPs.This study suggests that low chiroptical activity nanomaterials would not affect the metabolism and kinetics under physiological conditions even if there is some difference in their transport. | Si Li Liwei Xu Meiru Lu Maozhong Sun Liguang Xu Changlong Hao Xiaoling Wu Chuanlai Xu Hua Kuang | 2021 | Nano Research2021，14，7： | 0 |
| 13 | Multi-photon Up-conversion Luminescence of ErP_(5)O_(14) Noncrystalline显示文摘In this paper we report the observation of multi-photon up-conversion luminescence phenomenon of ErP_(5)O_(14) noncrystalline induced by pulse DCM dye laser and clarify that the mechanism of up-conversion is the step by step absorption of single Er^(3+)ion. | CHEN Xiaobo ZHANG Guangyin WANG Hong LIU Yanbin LI Jiaji CHEN Jinkai ZHANG Wanlin SHANG Meiru | 1993 | Chinese Physics Letters1993，10，4： | 0 |
| 14 | The 450 nm Up-Conversion Fluorescence of Crystalline TmP_(5)O_(14)显示文摘This paper reports the 450 nm up-conversion Buorescence of the crystalline TmP_(5)O_(14) at room temperature induced by pulsed DCM dye laser.It is iound that the up-conversion mechanism is the excited st&te absorption. | CHEN Xiaobo ZHANG Guangyin CHEN Jinkai SHANG Meiru LI Jiangwei | 1993 | Chinese Physics Letters1993，10，11： | 0 |
| 15 | Electromagnetic Technology for Vacuum Metrology in the Typical Development of a Metrological-Grade Spinning Rotor Gauge显示文摘As the most precise viscous vacuum gauge,the spinning rotor gauge is widely used in the aerospace,nuclear,semiconductor,and other fields because of its excellent accuracy and chemical inertness.Herein,a metrological-grade spinning rotor vacuum gauge is developed,and its performance is evaluated.It can be used for international comparison of vacuum standards and construction of national vacuum measurement traceability and transmission systems.This paper presents the design of a single-degree-of-freedom permanent magnet-biased rotor suspension system,a high-speed rotary stepper drive system,a rotational angular velocity determination system,a lateral damping system,and a transducer in detail.The change in residual drag is less than 0.49%after 50 minutes of start-up.There is good consistency and linearity in the range of 9.1727×10^(−5)Pa to 1.2081 Pa. | Detian Li Meiru Guo Zhenhua Xi Huzhong Zhang Bowen Li | 2023 | Electromagnetic Science2023，1，3： | 0 |
| 16 | Knockdown of LjALD1, AGD2‐like defense response protein 1, influences plant growth and nodulation in Lotus japonicus显示文摘The discovery of the enzyme L,L‐diaminopimelate aminotransferase(LL‐DAP‐AT, EC 2.6.1.83) uncovered a unique step in the L‐lysine biosynthesis pathway in plants. In Arabidopsis thaliana, LL‐DAP‐AT has been shown to play a key role in plant‐pathogen interactions by regulation of the salicylic acid(SA) signaling pathway. Here, a full‐length cDNA of LL‐DAP‐AT named as LjALD1 from Lotus japonicus(Regel)Larsen was isolated. The deduced amino acid sequence shares 67% identity with the Arabidopsis aminotransferase AGD2‐LIKE DEFENSE RESPONSE PROTEIN1(AtALD1) and is predicted to contain the same key elements: a conserved aminotransferase domain and a pyridoxal‐5'‐phosphate cofactor binding site.Quantitative real‐time PCR analysis showed that LjALD1 was expressed in all L. japonicus tissues tested, being strongest in nodules. Expression was induced in roots that had been infected with the symbiotic rhizobium Mesorhizobium loti or treated with SA agonist benzo‐(1, 2, 3)‐thiadiazole‐7‐carbothioic Researchacid. LjALD1 Knockdown exhibited a lower SA content, an increased number of infection threads and nodules, and a slight reduction in nodule size. In addition, compared with wild‐type,root growth was increased and shoot growth was suppressed in LjALD1 RNAi plant lines. These results indicate that LjALD1 may play important roles in plant development and nodulation via SA signaling in L. japonicus. | Wei Chen Xueliu Li Lu Tian Pingzhi Wu Meiru Li Huawu Jiang Yaping Chen Guojiang Wu | 2014 | Journal of Integrative Plant Biology2014，56，11： | 0 |
| 17 | Degradation of iodinated X-ray contrast media by advanced oxidation processes:A literature review with a focus on degradation pathways显示文摘Available online Iodinated X-ray contrast media (ICMs) are clinical drugs used to enhance the imaging effect.Triiodobenzene ring structures of ICMs lead to its extremely high chemical stability,biological inertness,which makes it difficult to be completely removed by traditional water treatment processes.Hence,considerable concentration of ICMs can be frequently detected in aquatic environment.Relying on the strong oxidation capacity of HO·or SO_(4)^(·-),various advanced oxidation processes (AOPs) have demonstrated substantial removal efficiency for ICMs.It is evident that ICMs can be decomposed mainly through(1) deiodination,(2) dehydration,(3) decarboxylation,(4) H-abstraction,(5) hydroxyl addition,(6) hydroxyl substitution,(7) oxidation of alcohol groups,(8) cleavage of amide bond,and (9) amino oxidation.However,during the ICMs removal process,the C-I bonds of ICMs molecules are broken,giving rise to the formation of cytotoxic iodination disinfection by-products (I-DBPs) that are potentially more harmful to the ecosystem and human health than their parent compounds.To better understand the technology gaps,this review elaborates the major AOPs which are effective for ICMs removal and emphasizes on the main degradation routes of ICMs in different oxidation system.Some prevailing concerns and challenges are discussed for optimizing the ICMs treatment process. | Meiru Hou Xiaodie Li Yu Fu Lingli Wang Dagang Lin Zhaohui Wang | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
| 18 | A chronological review of photochemical reactions of ferrioxalate at the molecular level:New insights into an old story显示文摘Owing to its outstanding photoactivity,ferrioxalate is originally used as an actinometer and subsequent work has discovered that photochemistry of ferrioxalate is also fundamentally or technically important in atmospheric chemistry and water treatment.While the overall products generated from photolysis of ferrioxalate are known to include Fe(Ⅱ),a series of oxidizing(e.g.,·OH,O_(2)^(·-)/HO_(2)^(·-))or reducing(C_(2)O_(4)^(·-)/CO_(2)^(·-))radicals and H_(2)O_(2),however,at the molecular level,the primary step of the photoreaction of ferrioxalate remains as an unsolved mystery due to the difficulty in examining such ultrafast processes.Benefiting from the development of time-resolved spectroscopy,this old question has been studied with increasing vigor recently,by means of such ever-more-sophisticated techniques(e.g.,flash photolysis,time-resolved X-ray absorption spectroscopy(XAS),femtosecond infrared(IR)absorption spectroscopy,ultrafast photoelectron spectroscopy(PES)).There are two contrary views on the primary reaction mechanism:(1)Intramolecular electron transfer(ET)precedes the cleavage of the metal-ligand bond;(2)The dissociation of C-C or Fe-O bond occurs before intramolecular ET.Thus,this review presents a comprehensive summary about the overall reaction mechanism and molecular level mechanism of ferrioxalates.In chronological order,we have elaborated two predominant but controversial views from the perspectives of different experimental approaches.Some challenges and research opportunities in this active field are also briefly discussed. | Xiaodie Li Meiru Hou Yu Fu Lingli Wang Yifan Wang Dagang Lin Qingchao Li Dongdong Hu Zhaohui Wang | 2023 | Chinese Chemical Letters2023，34，5： | 0 |
| 19 | Effect of LaCl_3 on the chilling tolerance of rice seedlings显示文摘The rice variety Tesanai 2 is susceptible to chilling. Exposure of the seedlings grown at 28±1℃ and under a photo flux density(PFD) of 30 μmol/m^2s to 1℃ and under a PFD of 150μmol/m^2s for 2 d caused a physiological disorder called chilling injury which reduced the survival rate to 50%. | LI Meiru LIU Hongxian WANG Yirou South China Inst of Botany,Academia Sinica,Guangzhou 510650,China | 1997 | Chinese Rice Research Newsletter1997，5，2： | 0 |
| 20 | Calcium effect on the process of cold-hardening of rice seedlings显示文摘Low temperature is an important environmental factor that limits the productivity and distribution of plant . The ability to cold acclimation is a common adaptive response in plants natiye in temperate regions and results in enhancing tolerance to chílling stress. | LI Meiru, LIU Hongxian, WANG Yirou, and ZENG Shaoxi, South China Inst of Botany, Academia Sinica, Guangzhou 510650, China | 1997 | Chinese Rice Research Newsletter1997，5，3： | 0 |
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