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| 1 | BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis显示文摘冷应力是不利地影响植物生长和开发的一个主要环境因素。C 重复有约束力的 factor/DRE 绑定因素 1 (CBF/DREB1 ) 规章的串联被显示出在对的植物反应起重要作用的 transcriptional 冷。这里,我们证明发信号的 brassinosteroid (BR ) 的二个关键部件调制 Arabidopsis 植物的结冰忍耐。象 GSK3 一样 kinases 的 loss-of-function 异种在 BR 发信号包含了, bin2-3 bil1 bil2,显示出的增加的结冰公差,而 BIN2 的 overexpression 导致了超敏性到结冰,在 non-acclimated 和 acclimated 下面的应力调节。由对比,显示的抄写因素 BZR1 和 BES1 的 gain-of-function 异种提高了结冰忍耐,和一致地冷的处理能导致 dephosphorylated BZR1 的累积。生物化学、基因的分析证明 BZR1 行动 CBF1 和 CBF2 到在上游直接调整他们的表示。而且,我们发现 BZR1 也调整了另外的英国管基因与 CBF 解开了例如 WKRY6, PYL6, SOC1, JMT,和 SAG21,种反应调制到冷应力。一致地, wrky6 异种显示出减少的结冰忍耐。一起拿,我们的结果显示 BZR1 断然调制通过 CBF 依赖、 CBF 独立的小径冻结忍耐的植物。 | Hui Li Keyi Ye Yiting Shi Jinkui Cheng Xiaoyan Zhang Shuhua Yang | 2017 | Molecular Plant2017，10，4： | 37 |
| 2 | Alterations of DNA damage response pathway:Biomarker and therapeutic strategy for cancer immunotherapy显示文摘Genomic instability remains an enabling feature of cancer and promotes malignant transformation.Alterations of DNA damage response(DDR)pathways allow genomic instability,generate neoantigens,upregulate the expression of programmed death ligand 1(PD-L1)and interact with signaling such as cyclic GMPe AMP synthase-stimulator of interferon genes(cGASe STING)signaling.Here,we review the basic knowledge of DDR pathways,mechanisms of genomic instability induced by DDR alterations,impacts of DDR alterations on immune system,and the potential applications of DDR alterations as biomarkers and therapeutic targets in cancer immunotherapy. | Minlin Jiang Keyi Jia Lei Wang Wei Li Bin Chen Yu Liu Hao Wang Sha Zhao Yayi He Caicun Zhou | 2021 | Acta Pharmaceutica Sinica B2021，11，10： | 12 |
| 3 | Electrochemically driven conversion reaction in fluoride electrodes for energy storage devices显示文摘Exploring electrochemically driven conversion reactions for the development of novel energy storage materials is an important topic as they can deliver higher energy densities than current Li-ion battery electrodes.Conversion-type fluorides promise particularly high energy densities by involving the light and small fluoride anion,and bond breaking can occur at relatively low Li activity(i.e.,high cell voltage).Cells based on such electrodes may become competitors to other envisaged alternatives such as Lisulfur or Li-air systems with their many unsolved thermodynamic and kinetic problems.Relevant conversion reactions are typically multiphase redox reactions characterized by nucleation and growth processes along with pronounced interfacial and mass transport phenomena.Hence significant overpotentials and nonequilibrium reaction pathways are involved.In this review,we summarize recent findings in terms of phase evolution phenomena and mechanistic features of(oxy)fluorides at different redox stages during the conversion process,enabled by advanced characterization technologies and simulation methods.It can be concluded that well-designed nanostructured architectures are helpful in mitigating kinetic problems such as the usually pronounced voltage hysteresis.In this context,doping and open-framework strategies are useful.By these tools,simple materials that are unable to allow for substantial Li nonstoichiometry(e.g.,by Li-insertable channels)may be turned into electroactive materials. | Chilin Li Keyi Chen Xuejun Zhou Joachim Maier | 2018 | npj Computational Materials2018，，1： | 8 |
| 4 | Statistical analysis of mesoscale eddy propagation velocity in the South China Sea deep basin显示文摘Using mesoscale eddy trajectory product derived from satellite altimetry data from 1993 to 2017,this study analyzes the statistical characteristics of spatiotemporal distribution of mesoscale eddy propagation velocities(C)in the South China Sea(SCS)deep basin with depths>1000 m.Climatologically,the zonal propagation velocities(cx)are westwards in the whole basin,and the meridional velocities(cy)are southwards in the northwestern basin,and northwards in the southeastern basin.The variation of cy with longitude is consistent with that of the background meridional currents with correlation coefficient R2 of 0.96,while the variation of cx is related both to the background zonal currents andβeffect.The propagation velocities characterize significant seasonality with the minimum magnitude occurring in summer and the maximum in winter for cx and C.Interannually,larger values of cx and cy mostly occurred in La Ni?a years in the negative phase of the Pacific Decadal Oscillation(PDO).Mesoscale eddies move fast at the beginning and end of their life span,i.e.,at their growth and dissipation periods,and slowly during their stable'midlife'period.This trend is negatively correlated with the rotating tangential velocity with R2 of–0.93.Eddies with extreme propagation velocities are defined,which are slower(faster)than 1.5 cm/s(15.4 cm/s)and take 1.5%(1.9%)of the total eddies.The extremely slow-moving(fastmoving)eddies tend to appear in the middle(on the edge)of the basin,and mostly occur in summer(winter).The mechanism analysis reveals that the spatiotemporal distributions of the propagation velocities of mesoscale eddies in the SCS are modulated by the basin-scale background circulation. | Runqi Huang Lingling Xie Quanan Zheng Mingming Li Peng Bai Keyi Tan | 2020 | Acta Oceanologica Sinica2020，39，11： | 4 |
| 5 | Global perspectives and future research directions for the phytoremediation of heavy metal-contaminated soil:A knowledge mapping analysis from 2001 to 2020显示文摘In total,9,552 documents were extracted from the Web of Science Core Collection and subjected to knowledge mapping and visualization analysis for the field of phytoremediation of HM-contaminated soil(PHMCS)with CiteSpace 5.7 R3 software.The results showed that(1)the number of publications increased linearly over the studied period.The top 10 countries/regions,institutions and authors contributing to this field were exhibited.(2)Keyword co-occurrence cluster analysis revealed a total of 8 clusters,including“Bioremediation,”“Arsenic,”“Biochar,”“Oxidative stress,”“Hyperaccumulation,”“EDTA,”“Arbuscular mycorrhizal fungi,”and“Environmental pollution”clusters(3)In total,334 keyword bursts were obtained,and the 25 strongest,longest duration,and newest keyboard bursts were analyzed in depth.The strongest keyword burst test showed that the hottest keywords could be divided into 7 groups,i.e.,“Plant bioremediation materials,”“HM types,”“Chelating amendments,”“Other improved strategies,”“Bioremediation characteristics,”“Risk assessment,”and“Other.”Almost half of the newest topics had emerged in the past 3 years,including“biochar,”“drought,”“health risk assessment,”“electrokinetic remediation,”“nanoparticle,”and“intercropping.”(4)In total,9 knowledge base clusters were obtained in this study.The studies of Ali et al.(2013),Blaylock et al.(1997),Huang et al.(1997),van der Ent et al.(2013),Salt et al.(1995),and Salt(1998),which had both high frequencies and the strongest burst scores,have had the most profound effects on PHMCS research.Finally,future research directions were proposed. | Kehui Liu Xiaojin Guan Chunming Li Keyi Zhao Xiaohua Yang Rongxin Fu Yi Li Fangming Yu | 2022 | Frontiers of Environmental Science & Engineering2022，16，6： | 4 |
| 6 | Horizontal shaking table tests and analysis on structures with multi-dimensional earthquake isolation and mitigation devices显示文摘The viscoelastic multi-dimensional earthquake isolation and mitigation device is a new kind of passive control device, which has both earthquake isolation and earthquake mitigation abilities. In order to quantify the horizontal earthquake isolation and mitigation effect of this device on structures, shaking table tests on structures with and without the devices and the corresponding analysis on earthquake isolation and mitigation properties are carried out. It can be shown from the experimental and analytical results that the device has both earthquake isolation and earthquake mitigation effects on structures in horizontal direction, and its horizontal earthquake mitigation coefficients can be referred to those of the rubber bearing earthquake isolation structure. | ZhaoDong Xu Xiao Zeng KeYi Wu AiQun Li QingYang Xu | 2009 | Science China(Technological Sciences)2009，52，7： | 3 |
| 7 | Determining the critical size of a rabbit rib segmental bone defect model显示文摘In order to establish and standardize the rabbit rib segmental bone defect model,it is of vital importance to determine rabbit rib critical size defect(CSD).According to the general time needed for spontaneous long-bone regeneration,three-month observation period was set to determine the CSD.The rabbit rib segmental bone defects with different sizes from 1 to 5cm with or without periosteum were performed in the eighth rib of 4-month-old male New Zealand rabbits and underwent Xray examinations at the 4th,8th and 12th weeks postoperatively.The gross and histological examinations at postoperative week 12 were evaluated,which showed that the critical sizes in the rabbit rib models with and without periosteum were 5 and 2 cm,respectively.This study provides prerequisite data for establishing rabbit rib CSD model and evaluating bonematerials using this model. | Fengzhen Liu Kun Chen Lei Hou Keyi Li Dawei Wang Bin Zhang Xiumei Wang | 2016 | Regenerative Biomaterials2016，3，5： | 2 |
| 8 | Effects of glycerol on apoptotic signaling pathways during boar spermatozoa cryopreservation显示文摘 | Changjun Zeng Keyi Tang Lian He Wenpei Peng Li Ding Donghui Fang Yan Zhang | 2014 | Cryobiology2014，，： | 2 |
| 9 | Synergistic effect between a novel hyperbranched flame retardant and melamine pyrophosphate on the char forming of polyamide 6显示文摘 | Keyi Fang Juan Li Chenhao Ke | | 0，，49： | 1 |
| 10 | Synergistic Effect Between a Novel Hyperbranched Flame Retardant and Melamine Pyrophosphate on the Char Forming of Polya- mide 6显示文摘 | Keyi Fang Juan Li Chenhao Ke | 2010 | Polymer-Plastics Technology and Engineering2010，49，： | 1 |
| 11 | Enhancement of a Hyperbranched Charring and Foaming Agent on Flame Retardaney of Polyamide 6显示文摘 | Chenhao Ke Juan Li Keyi Fang | 2011 | Polym Adv Technol2011，22，： | 1 |
| 12 | Enhancement of a Hyperbranched Charring and Foaming Agent on Flame Retardancy of Polyamide 6 显示文摘 | Ke Chenhao Li Juan Fang Keyi | 2011 | Polymers for Advanced Technologies2011，，： | 1 |
| 13 | Synergistic Effect Between a Novel Hyperbranched Charring Agent and Ammonium Polyphosphate on the Flame Retardant and Anti-dripping Properties of Polylactide 显示文摘 | Ke Chenhao Li Juan Fang Keyi | 2010 | Polymer De- gra- dation and Stability2010，95，5： | 1 |
| 14 | Evaluation of All-Sky Assimilation of FY-3C/MWHS-2 on Mei-yu Precipitation Forecasts over the Yangtze-Huaihe River Basin显示文摘All-sky (i.e., clear, cloudy, and precipitating conditions) assimilation of microwave observations shows potentially positive impacts on the improvement of the forecasts of cloud-associated weather processes. In this study, a typical mei-yu heavy precipitation event that occurred in 2017 was investigated, and the Weather Research and Forecasting data assimilation (WRFDA) as well as its 3D-Var assimilation scheme (excluding cloud and precipitation control variables) were applied to assimilate the Fengyun-3C (FY-3C) Microwave Humidity Sounder-2 (MWHS-2) observations under clear- sky (excluding the observations that are strongly affected by ice clouds and precipitation) and all-sky conditions. Three experiments including a control experiment without assimilating any observations, clear-sky, and all-sky experiments with only FY-3C/MWHS-2 observations assimilated were carried out. The results show that the all-sky assimilation approach that provides more cloud and precipitation information and increased more than 10% of the satellite data usage than the clear-sky experiment. Meanwhile, as compared with the control experiment, the all-sky assimilation reduced nearly 0.5% of the root mean square errors in the humidity fields, leading to more accurate forecast performances regarding the distribution and intensity of heavy rainfall;but it exhibited a neutral to negative impacts on the wind and temperature. Although the system used to conduct all-sky assimilation is only able to adjust control variables for moisture-, wind-, and temperature- related variables in the presence of cloud and does not benefit directly from cloud or precipitation information, the positive effects on heavy rainfall forecasts achieved in this study indicate a potential future benefit regarding disaster prevention and mitigation. | Yu LI Keyi CHEN Zhipeng XIAN | 2021 | Advances in Atmospheric Sciences2021，38，8： | 1 |
| 15 | Mass Spectrometry Analysis of SARS-CoV-2 Nucleocapsid Protein Reveals Camouflaging Glycans and Unique Post-Translational Modifications显示文摘The devastating coronavirus disease 2019(COVID-19)pandemic has prompted worldwide efforts to study structural biological traits of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its viral components.Compared to the Spike protein,which is the primary target for currently available vaccines or antibodies,knowledge about other virion structural components is incomplete.Using high-resolution mass spectrometry,we report a comprehensive post-translational modification(PTM)analysis of nucleocapsid phosphoprotein(NCP),the most abundant structural component of the SARS-CoV-2 virion.In addition to phosphoryl groups,we show that the SARS-CoV-2 NCP is decorated with a variety of PTMs,including N-glycans and ubiquitin.Based on newly identified PTMs,refined protein structural models of SARS-CoV-2 NCP were proposed and potential immune recognition epitopes of NCP were aligned with PTMs.These data can facilitate the design of novel vaccines or therapeutics targeting NCP,as valuable alternatives to the current vaccination and treatment paradigm that is under threat of the ever-mutating SARS-CoV-2 Spike protein. | Zeyu Sun Xiaoqin Zheng Feiyang Ji Menghao Zhou Xiaoling Su Keyi Ren Lanjuan Li | 2021 | Infectious Microbes & Diseases2021，3，3： | 1 |
| 16 | Synergistic Effect Between a Novel Hyperbranched Charring Agent and Ammonium Polyphosphate on the Flame Retardant and Anti dripping Properties of Polylactide显示文摘 | Ke Chenhao Li Juan Fang Keyi | 2010 | Polymer Deg radation and Stability2010，95，： | 1 |
| 17 | Complex Motion Modeling and State Estimation in Road Coordinates显示文摘Constrained modeling and state estimation have attracted much attention in recent years. This paper focuses on target motion modeling and tracking in road coordinates. An improved initialization method,which uses the optimal fusion of the position measurements in different directions,is presented for the constraint coordinate Kalman filter(CCKF). The CCKF is evaluated with a comprehensive comparison to the state-of-art linear equality constraint estimation methods. Numerical simulation results demonstrate the better performance of the CCKF. Then the interacting multiple model CCKF(IMM-CCKF) is proposed to manifest the advantages of the CCKF in complex motion modeling and state estimations. The effectiveness of the IMM-CCKF in maneuvering target tracking with spatial equality constraints is demonstrated by numerical experiments. | Keyi Li Xi Chen Gongjian Zhou | 2017 | Journal of Harbin Institute of Technology(New Series)2017，24，1： | 1 |
| 18 | Polymer electrolytes reinforced by 2D fluorinated filler for all-solidstate Li-Fe-F conversion-type lithium metal batteries显示文摘The polyethylene oxide(PEO)based solid-state batteries are considered as promising candidates for the next-generation Li metal batteries with high energy density and safety.However,the low Li-ion conductivity and high-voltage endurability hinder the further applications of PEO-based electrolytes.To overcome these issues,herein two-dimensional(2D)CeF_(3)nanoplates with maximally exposed[001]crystal faces are introduced into the PEO matrix to expand the electrochemical window and improve Liion conduction and transport.The optimized crystal shape and crystal face anisotropy of CeF_(3)nanoplate filler reduce the crystallinity of composite solid polymer electrolyte(CSPE)via its Lewis acid-base interaction with ether oxygen of PEO.The Liaffinity[100]and Li-repellent[001]crystal faces of CeF_(3)nanoplates synergistically realize the dissociation of lithium bis(trifluoromethanesulfonyl)imide(LiTFSI),fast Li-adsorption/desorption,and Li+migration.The optimized CSPE-0.1CeF_(3)membrane enables the achievement of Li metal batteries with high endurability and stability,from the kinetically favorable Li/Li symmetric cells with long-term cycling over 8000 h.The highly reversible Li/LiFePO_(4) cells exhibit a capacity retention of 109.2 mAh·g^(−1)after 1000 cycles at 1 C,corresponding to a low capacity fading rate of 0.026%per cycle.The conversion-type allsolid-state Li/CSPE-0.1CeF_(3)/FeF_(3)cells show a high reversible capacity of 201.9 mAh·g^(−1)after long-term 600 cycles and of 231.1 mAh·g^(−1)at an ultra-high rate of 5 C. | Meng Lei Xiaoxue Wu Yangyang Liu Keyi Chen Jiulin Hu Chilin Li | 2023 | Nano Research2023，16，6： | 1 |
| 19 | Synergistic effect between anovel hyperbranched charring agent and ammonium polyphosphate on the flame retardant and anti-dripping properties of polylactide显示文摘 | Ke Chenhao Li Juan Fang Keyi | 2010 | Polymer Degradation and Stability2010，95，5： | 1 |
| 20 | Inductance computation consideration of induction coil launcher显示文摘 | Zhao Keyi Lei Bin Li Zhiyuan | 2009 | IEEE Transactions on Magnetics2009，45，1： | 1 |
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