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| 1 | Alterations of DNA damage response pathway:Biomarker and therapeutic strategy for cancer immunotherapy显示文摘Genomic instability remains an enabling feature of cancer and promotes malignant transformation.Alterations of DNA damage response(DDR)pathways allow genomic instability,generate neoantigens,upregulate the expression of programmed death ligand 1(PD-L1)and interact with signaling such as cyclic GMPe AMP synthase-stimulator of interferon genes(cGASe STING)signaling.Here,we review the basic knowledge of DDR pathways,mechanisms of genomic instability induced by DDR alterations,impacts of DDR alterations on immune system,and the potential applications of DDR alterations as biomarkers and therapeutic targets in cancer immunotherapy. | Minlin Jiang Keyi Jia Lei Wang Wei Li Bin Chen Yu Liu Hao Wang Sha Zhao Yayi He Caicun Zhou | 2021 | Acta Pharmaceutica Sinica B2021,11,10: | 12 |
| 2 | Electrochemically driven conversion reaction in fluoride electrodes for energy storage devices显示文摘Exploring electrochemically driven conversion reactions for the development of novel energy storage materials is an important topic as they can deliver higher energy densities than current Li-ion battery electrodes.Conversion-type fluorides promise particularly high energy densities by involving the light and small fluoride anion,and bond breaking can occur at relatively low Li activity(i.e.,high cell voltage).Cells based on such electrodes may become competitors to other envisaged alternatives such as Lisulfur or Li-air systems with their many unsolved thermodynamic and kinetic problems.Relevant conversion reactions are typically multiphase redox reactions characterized by nucleation and growth processes along with pronounced interfacial and mass transport phenomena.Hence significant overpotentials and nonequilibrium reaction pathways are involved.In this review,we summarize recent findings in terms of phase evolution phenomena and mechanistic features of(oxy)fluorides at different redox stages during the conversion process,enabled by advanced characterization technologies and simulation methods.It can be concluded that well-designed nanostructured architectures are helpful in mitigating kinetic problems such as the usually pronounced voltage hysteresis.In this context,doping and open-framework strategies are useful.By these tools,simple materials that are unable to allow for substantial Li nonstoichiometry(e.g.,by Li-insertable channels)may be turned into electroactive materials. | Chilin Li Keyi Chen Xuejun Zhou Joachim Maier | 2018 | npj Computational Materials2018,,1: | 8 |
| 3 | Growing Operational Use of FY-3 Data in the ECMWF System显示文摘This paper reviews the data quality and impact of observations from the FY-3 satellite series used operationally in the ECMWF system. This includes data from the passive microwave radiometers MWHS-1, MWHS-2 and MWRI, as well as observations from the radio occultation receiver GNOS. Evaluations against background equivalents show that the quality of the observations is broadly comparable to that of similar instruments on other polar-orbiting satellites, even though biases for the passive microwave observations can be somewhat larger and more complex for some channels. An observing system experiment shows that the FY-3 instruments jointly contribute significantly to the forecast skill in the ECMWF system. Positive impact of up to 2% is seen for most variables out to the day-2 forecasts over hemispheric scales, with significant benefits for total column water vapor or for temperature and wind in the stratosphere out to day 4. | Niels BORMANN David DUNCAN Stephen ENGLISH Sean HEALY Katrin LONITZ Keyi CHEN Heather LAWRENCE Qifeng LU | 2021 | Advances in Atmospheric Sciences2021,38,8: | 3 |
| 4 | A Potential Global Standard Stratotype-Section and Point of the Moscovian Stage(Carboniferous)显示文摘Conodonts 和 fusulinids 是为细分和相关 Bashkirian 和 Moscovian 阶层的二个最广泛地使用的关於生命的组。因为在存在边界定义建议,其各个有劣势之中有许多争论,全球 Moscovian 阶段的底的定义是未定的。Declinognathodus donetzianus 容易在它的 paleogeographic 分发被认出,但是有点限制了。Idiognathoides postsulcatus 是稍微更普遍的,但是它不太容易被识别,它的出现可以是从区域的 diachronous 到区域。Diplognathodus ellesmerensis 容易被认出并且甚至更普遍,但是它通常是稀罕的,它的祖先足够地不被知道。南方贵州的 Naqing 节,华南包含多样的 conodont 在不同 taxa,包括的 Idiognathoides, Idiognathodus, Diplognathodus, Neognathodus, Gondolella 和 Mesogondolella 之中的进化的系。在有众多的过渡形式几乎 Naqing 节的每个系,哪个为华南的前景上演在决定基础 Moscovian 起一个关键作用的表演定义好。 | WANG Xiangdong QI Yuping Lance LAMBERT WANG Zhihao WANG Yue HU Keyi LIN Wei CHEN Bo | 2011 | Acta Geologica Sinica(English Edition)2011,85,2: | 3 |
| 5 | Determining the critical size of a rabbit rib segmental bone defect model显示文摘In order to establish and standardize the rabbit rib segmental bone defect model,it is of vital importance to determine rabbit rib critical size defect(CSD).According to the general time needed for spontaneous long-bone regeneration,three-month observation period was set to determine the CSD.The rabbit rib segmental bone defects with different sizes from 1 to 5cm with or without periosteum were performed in the eighth rib of 4-month-old male New Zealand rabbits and underwent Xray examinations at the 4th,8th and 12th weeks postoperatively.The gross and histological examinations at postoperative week 12 were evaluated,which showed that the critical sizes in the rabbit rib models with and without periosteum were 5 and 2 cm,respectively.This study provides prerequisite data for establishing rabbit rib CSD model and evaluating bonematerials using this model. | Fengzhen Liu Kun Chen Lei Hou Keyi Li Dawei Wang Bin Zhang Xiumei Wang | 2016 | Regenerative Biomaterials2016,3,5: | 2 |
| 6 | Carboniferous integrative stratigraphy and timescale of China显示文摘The Carboniferous period lasted about 60 Myr, from ~358.9 Ma to ~298.9 Ma. According to the International Commission on Stratigraphy, the Carboniferous System is subdivided into two subsystems, i.e., Mississippian and Pennsylvanian, including 6 series and 7 stages. The Global Stratotype Sections and Points(GSSPs) of three stages have been ratified, the Tournaisian, Visean, and Bashkirian stages. The GSSPs of the remaining four stages(i.e., the Serpukhovian, Moscovian,Kasimovian, and Gzhelian) have not been ratified so far. This paper outlines Carboniferous stratigraphic subdivision and correlation on the basis of detailed biostratigraphy mainly from South China, and summarizes the Carboniferous chronostratigraphic framework of China. High-resolution biostratigraphic study reveals 37 conodont zones, 24 foraminiferal(including fusulinid) zones, 13 ammonoid zones, 10 brachiopod zones, and 10 rugose coral zones in the Carboniferous of China. The biostratigraphic framework based on these biozones warrants the precise correlation of regional stratigraphy of China(including2 subsystems, 4 series, and 8 stages) to that of the other regions globally. Meanwhile, the Carboniferous chemo-, sequence-,cyclo-, and event-stratigraphy of China have been intensively studied and can also be correlated worldwide. Future studies on the Carboniferous in China should focus on(1) the correlation between shallow-and deep-water facies and between marine and continental facies,(2) high-resolution astronomical cyclostratigraphy, and(3) paleoenvironment and paleoclimate analysis based on geochemical proxies such as strontium and oxygen isotopes, as well as stomatal indices of fossil plants. | Xiangdong WANG Keyi HU Wenkun QIE Qingyi SHENG Bo CHEN Wei LIN Le YAO Qiulai WANG Yuping QI Jitao CHEN Zhuoting LIAO Junjun SONG | 2019 | Science China Earth Sciences2019,62,1: | 2 |
| 7 | Assimilation of Feng-Yun-3B Satellite Microwave Humidity Sounder Data over Land显示文摘The ECMWF has been assimilating Feng-Yun-3B(FY-3B) satellite microwave humidity sounder(MWHS) data over ocean in an operational forecasting system since 24 September 2014. It is more difficult, however, to assimilate microwave observations over land and sea ice than over the open ocean due to higher uncertainties in land surface temperature, surface emissivity and less effective cloud screening. We compare approaches in which the emissivity is retrieved dynamically from MWHS channel 1 [150 GHz(vertical polarization)] with the use of an evolving emissivity atlas from 89 GHz observations from the MWHS onboard NOAA and EUMETSAT satellites. The assimilation of the additional data over land improves the fit of short-range forecasts to other observations, notably ATMS(Advanced Technology Microwave Sounder) humidity channels, and the forecast impacts are mainly neutral to slightly positive over the first five days. The forecast impacts are better in boreal summer and the Southern Hemisphere. These results suggest that the techniques tested allow for effective assimilation of MWHS/FY-3B data over land. | Keyi CHEN Niels BORMANN Stephen ENGLISH Jiang ZHU | 2018 | Advances in Atmospheric Sciences2018,35,3: | 2 |
| 8 | Incorporating topographic factors in nonlinear mixed-effects models for aboveground biomass of natural Simao pine in Yunnan,China显示文摘A total of 128 Simao pine trees(Pinus kesiya var. langbianensis) from three regions of Pu'er City,Yunnan Province, People's Republic of China, were destructively sampled to obtain tree aboveground biomass(AGB). Tree variables such as diameter at breast height and total height, and topographical factors such as altitude,aspect of slope, and degree of slope were recorded. We considered the region and site quality classes as the random-effects, and the topographic variables as the fixedeffects. We fitted a total of eight models as follows: leastsquares nonlinear models(BM), least-squares nonlinear models with the topographic factors(BMT), nonlinear mixed-effects models with region as single random-effects(NLME-RE), nonlinear mixed-effects models with site as single random-effects(NLME-SE), nonlinear mixed-effects models with the two-level nested region and site random-effects(TLNLME), NLME-RE with the fixed-effects of topographic factors(NLMET-RE), NLME-SE with the fixed-effects of topographic factors(NLMET-SE), and TLNLME with the fixed-effects of topographic factors(TLNLMET). The eight models were compared by modelfitting and prediction statistics. The results showed: model fitting was improved by considering random-effects of region or site, or both. The models with the fixed-effects of topographic factors had better model fitting. According to AIC and BIC, the model fitting was ranked as TLNLME[ NLMET-RE [ NLME-RE [ NLMET-SE [ TLNLMET[ NLME-SE [ BMT [ BM. The differences among these models for model prediction were small. The model prediction was ranked as TLNLME [ NLME-RE [ NLMES E [ N L M E T- R E [ N L M E T- S E [ T L N L M E T [BMT [ BM. However, all eight models had relatively high prediction precision([90 %). Thus, the best model should be chosen based on the available data when using the model to predict individual tree AGB. | Guanglong Ou Junfeng Wang Hui Xu Keyi Chen Haimei Zheng Bo Zhang Xuelian Sun Tingting Xu Yifa Xiao | 2016 | Journal of Forestry Research2016,27,1: | 2 |
| 9 | Evaluation of All-Sky Assimilation of FY-3C/MWHS-2 on Mei-yu Precipitation Forecasts over the Yangtze-Huaihe River Basin显示文摘All-sky (i.e., clear, cloudy, and precipitating conditions) assimilation of microwave observations shows potentially positive impacts on the improvement of the forecasts of cloud-associated weather processes. In this study, a typical mei-yu heavy precipitation event that occurred in 2017 was investigated, and the Weather Research and Forecasting data assimilation (WRFDA) as well as its 3D-Var assimilation scheme (excluding cloud and precipitation control variables) were applied to assimilate the Fengyun-3C (FY-3C) Microwave Humidity Sounder-2 (MWHS-2) observations under clear- sky (excluding the observations that are strongly affected by ice clouds and precipitation) and all-sky conditions. Three experiments including a control experiment without assimilating any observations, clear-sky, and all-sky experiments with only FY-3C/MWHS-2 observations assimilated were carried out. The results show that the all-sky assimilation approach that provides more cloud and precipitation information and increased more than 10% of the satellite data usage than the clear-sky experiment. Meanwhile, as compared with the control experiment, the all-sky assimilation reduced nearly 0.5% of the root mean square errors in the humidity fields, leading to more accurate forecast performances regarding the distribution and intensity of heavy rainfall;but it exhibited a neutral to negative impacts on the wind and temperature. Although the system used to conduct all-sky assimilation is only able to adjust control variables for moisture-, wind-, and temperature- related variables in the presence of cloud and does not benefit directly from cloud or precipitation information, the positive effects on heavy rainfall forecasts achieved in this study indicate a potential future benefit regarding disaster prevention and mitigation. | Yu LI Keyi CHEN Zhipeng XIAN | 2021 | Advances in Atmospheric Sciences2021,38,8: | 1 |
| 10 | Mechani- cal property analysis with ultrasonic phased array显示文摘 | SONG Wenai YUAN Keyi CHEN Yifang | 2008 | Proceedings of 17th World Conf on NDT2008,,: | 1 |
| 11 | Complex Motion Modeling and State Estimation in Road Coordinates显示文摘Constrained modeling and state estimation have attracted much attention in recent years. This paper focuses on target motion modeling and tracking in road coordinates. An improved initialization method,which uses the optimal fusion of the position measurements in different directions,is presented for the constraint coordinate Kalman filter(CCKF). The CCKF is evaluated with a comprehensive comparison to the state-of-art linear equality constraint estimation methods. Numerical simulation results demonstrate the better performance of the CCKF. Then the interacting multiple model CCKF(IMM-CCKF) is proposed to manifest the advantages of the CCKF in complex motion modeling and state estimations. The effectiveness of the IMM-CCKF in maneuvering target tracking with spatial equality constraints is demonstrated by numerical experiments. | Keyi Li Xi Chen Gongjian Zhou | 2017 | Journal of Harbin Institute of Technology(New Series)2017,24,1: | 1 |
| 12 | Polymer electrolytes reinforced by 2D fluorinated filler for all-solidstate Li-Fe-F conversion-type lithium metal batteries显示文摘The polyethylene oxide(PEO)based solid-state batteries are considered as promising candidates for the next-generation Li metal batteries with high energy density and safety.However,the low Li-ion conductivity and high-voltage endurability hinder the further applications of PEO-based electrolytes.To overcome these issues,herein two-dimensional(2D)CeF_(3)nanoplates with maximally exposed[001]crystal faces are introduced into the PEO matrix to expand the electrochemical window and improve Liion conduction and transport.The optimized crystal shape and crystal face anisotropy of CeF_(3)nanoplate filler reduce the crystallinity of composite solid polymer electrolyte(CSPE)via its Lewis acid-base interaction with ether oxygen of PEO.The Liaffinity[100]and Li-repellent[001]crystal faces of CeF_(3)nanoplates synergistically realize the dissociation of lithium bis(trifluoromethanesulfonyl)imide(LiTFSI),fast Li-adsorption/desorption,and Li+migration.The optimized CSPE-0.1CeF_(3)membrane enables the achievement of Li metal batteries with high endurability and stability,from the kinetically favorable Li/Li symmetric cells with long-term cycling over 8000 h.The highly reversible Li/LiFePO_(4) cells exhibit a capacity retention of 109.2 mAh·g^(−1)after 1000 cycles at 1 C,corresponding to a low capacity fading rate of 0.026%per cycle.The conversion-type allsolid-state Li/CSPE-0.1CeF_(3)/FeF_(3)cells show a high reversible capacity of 201.9 mAh·g^(−1)after long-term 600 cycles and of 231.1 mAh·g^(−1)at an ultra-high rate of 5 C. | Meng Lei Xiaoxue Wu Yangyang Liu Keyi Chen Jiulin Hu Chilin Li | 2023 | Nano Research2023,16,6: | 1 |
| 13 | Deadlock avoidance policy for Petri net modeling of flexible manufacturing systems with shared resources显示文摘 | XING Keyi HU Baosheng CHEN Xiaoxun | 1996 | IEEE Transactions on Robotics and Automation1996,41,2: | 1 |
| 14 | Monitoring Mongolia Gobi dust transport using OMI data显示文摘The characteristics of long-distance dust transport from Asia to the United States over the Pacific Ocean are statistically analyzed using OMI AI (Ozone Monitoring Instrument Aerosol Index) data during 2005-2007. The results show that there is a high correlation of AI (the correlation coefficients are as high as 0.83 in March, 0.62 in April and 0.54 in May) between the Mongolia Gobi Desert and the west coast region of the United States (40°-50°N, 120°-130°W), indicating a strong source-receptor area relationship. Through calculating the lag correlation coefficient of the dust propagation time, we determined that the dust propagation time from the Mongolia Gobi Desert to the west coast of the United States is about 6-7 days at the 99% confidence level. | KeYi Chen ZhiQiang Peng | 2012 | Research in Cold and Arid Regions2012,4,5: | 0 |
| 15 | Nanodiamonds decorated yolk-shell ZnFe_(2)O_(4) sphere as magnetically separable and recyclable composite for boosting antibiotic degradation performance显示文摘Photocatalysis is an environmentally friendly and energy-saving technology, which can effectively remove persistent dangerous pollutants in the water. Pitifully, optical absorption capacity and carrier separation have become major bottlenecks for marvelous photocatalytic performance of photocatalysts.Herein, to address these issue, Nanodiamonds/yolk-shell ZnFe_(2)O_(4) spheres(NDs/ZFO) nanocomposites were successfully constructed via a facile two-step of solvothermal and calcination methods. The synthesized optimal NDs/ZFO-10 nanocomposite exhibits superior photocatalytic degradation activity of antibiotic under visible light, approximately 85% of the total tetracycline(TC) is degraded, and this photocatalyst shows durable cycling stability. This stems from two aspects of refinement: improvement of light absorption capacity and photo-induced charges migration and separation. In addition, the NDs/ZFO composite photocatalyst features excellent magnetic recovery capability, facilitating the recovery of photocatalyst in industry. This study opens a new chapter in the combination of NDs with magnetic materials, and deepens the understanding of the application of NDs modified composite photocatalysts. | Jingjing Pan Haoran Sun Keyi Chen Yuhao Zhang Pengnian Shan Weilong Shi Feng Guo | 2023 | Chinese Journal of Chemical Engineering2023,54,2: | 0 |
| 16 | Tailored deep-eutectic solvent method to enable 3D porous iron fluoride bricks for conversion-type lithium batteries显示文摘Conversion-type fluoride cathode can provide considerable energy density for Li batteries,however its scalable and facile synthesis strategies are still lacking.Here,a novel Fe-based deep eutectic solvent composed of nitrite and methylsulfonylmethane is proposed as both the reaction medium and precursor to synthesize O-doped FeF3porous bricks.This method is cheaper,safe,mildly operable,environmentally friendly and recyclable for non-fluorinated metal cations.The homogenization of charge and mass transport in cathode network effectively mitigates the volume extrusion and electrode coarsening even for the micro-sized monolithic particles.The Co-solvation modulated fluoride cathode delivers high reversible capacity in a wide temperature range(486 and 235 mA h g^(-1)at 25℃ and-20℃ respectively),excellent rate performance(312 mA h g^(-1)at 1000 mA g^(-1)),corresponding to an energy density as high as672.1 W h kg^(-1)under a power density of 2154.3 W kg^(-1).The successful operation of fluoride pouchcell with a capacity exceeding 450 mA h g^(-1)(even under thin Li foil and lean electrolyte conditions) indicates its potentiality of commercial application. | Chuanzhong Lai Keyi Chen Yongjian Zheng Junwei Meng Jiulin Hu Chilin Li | 2023 | Journal of Energy Chemistry2023,,3: | 0 |
| 17 | A prospective cohort study on serum A20 as a prognostic biomarker of aneurysmal subarachnoid hemorrhage显示文摘BACKGROUND:A20 may be a neuroprotective factor.Herein,we aimed to investigate whether serum A20 levels were associated with disease severity,delayed cerebral ischemia(DCI),and outcome after aneurysmal subarachnoid hemorrhage(aSAH).METHODS:In this prospective cohort study containing 112 aSAH patients and 112 controls,serum A20 levels were quantified.At 90 d poststroke,Modified Rankin Scale(MRS) scores≥3 were defined as a poor outcome.All correlations and associations were assessed using multivariate analysis.RESULTS:Compared with controls,there was a significant elevation of serum A20 levels in patients(median 123.7 pg/mL vs.25.8 pg/mL;P<0.001).Serum A20 levels were independently correlated with Hunt-Hess scores(β 9.854;95% confidence interval [95% CI] 2.481-17.227,P=0.009) and modified Fisher scores(β 10.349,95% CI 1.273-19.424,P=0.026).Independent associations were found between serum A20 levels and poor outcome(odds ratio [OR] 1.015,95%CI 1.000-1.031,P=0.047) and DCI(OR 1.018,95% CI 1.001-1.035,P=0.042).Areas under the curve for predicting poor outcome and DCI were 0.771(95% CI 0.682-0.845) and 0.777(95% CI 0.688-0.850),respectively.Serum A20 levels ≥128.15 pg/mL predicted poor outcome,with a sensitivity of 73.9% and specificity of 74.2%,and A20 levels ≥160.55 pg/mL distinguished the risk of DCI with65.5% sensitivity and 89.2% specificity.Its ability to predict poor outcome and DCI was similar to those of Hunt-Hess scores and modified Fisher scores(both P>0.05).CONCLUSION:Enhanced serum A20 levels are significantly associated with stroke severity and poor clinical outcome after aSAH,implying that serum A20 may be a potential prognostic biomarker for aSAH. | Tian Yan Ziyin Chen Shengdong Zou Zefan Wang Quan Du Wenhua Yu Wei Hu Yongke Zheng Keyi Wang Xiaoqiao Dong Shuangyong Dong | 2023 | World Journal of Emergency Medicine2023,14,5: | 0 |
| 18 | PREPARATION OF HIGH T_(c) Pb-DOPED Bi-BASED SUPERCONDUCTING AMORPHOUS SOLID显示文摘The Pb-doped Bi-based amorphous solid has been prepared by the anvil quenching method from the melt.After annealing,we obtained the dense superconductor with onset and zero resistance temperature at 120K and 107K,respectively.X-ray powder diffraction(XRD)and selected area electron diffract ion(SAED)analysis show that there is mainly high Tc phase(2223 phase)in the sample,and scanning electron microscopy(SEM)observation of the surface of the sample reveals that the needle-like grain abound in sample.Energy dispersive analysis of X-ray(EDAX)indicates that the average composition of grains is Bi_(2)Pb_(0.3)Sr_(1.3)Ca_(1.7)Cu_(2.3)O_(δ). | CHEN Meiling LI Xiaoge WANG Keyi LI Shuzhen XU Shihong WU Chengjiu TANG Hongao | 1990 | Chinese Physics Letters1990,7,3: | 0 |
| 19 | Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications显示文摘The coronavirus disease 2019(COVID-19)pandemic has led to worldwide efforts to understand the biological traits of the newly identified human coronavirus(HCoV-19)virus.In this mass spectrometry(MS)-based study,we reveal that out of 21 possible glycosites in the HCoV-19 spike protein(S protein),20 are completely occupied by N-glycans,predominantly of the oligomannose type.All seven glycosylation sites in human angiotensin I converting enzyme 2(hACE2)were found to be completely occupied,mainly by complex N-glycans.However,glycosylation did not directly contribute to the binding affinity between HCoV-19 S protein and hACE2.Additional post-translational modification(PTM)was identified,including multiple methylated sites in both proteins and multiple sites with hydroxylproline in hACE2.Refined structural models of HCoV-19 S protein and hACE2 were built by adding N-glycan and PTMs to recently published cryogenic electron microscopy structures.The PTM and glycan maps of HCoV-19 S protein and hACE2 provide additional structural details for studying the mechanisms underlying host attachment and the immune response of HCoV-19,as well as knowledge for developing desperately needed remedies and vaccines. | Zeyu Sun Keyi Ren Xing Zhang Jinghua Chen Zhengyi Jiang Jing Jiang Feiyang Ji Xiaoxi Ouyang Lanjuan Li | 2021 | Engineering2021,7,10: | 0 |
| 20 | Single-cell transcriptome landscape and antigen receptor dynamic during SARS-CoV-2 vaccination显示文摘Vaccination by inactivated vaccine is an effective strategy to prevent the COVID-19pandemic.However,the detailed molecular immune response at single-cell level is poorly un-derstood.In this study,we systematically delineated the landscape of the pre-and post-vaccination single-cell transcriptome,TCR(T cell antigen receptor)and BCR(B cell antigen re-ceptor)expression profile of vaccinated candidates.The bulk TCR sequencing analysis of COV-ID-19 patients was also performed.Enrichment of a clonal CD8+T cell cluster expressingspecific TCR was identified in both vaccination candidates and COVID-19 patients.These clonalCD8+T cells showed high expression of cytotoxicity,phagosome and antigen presentationrelated genes.The cellecell interaction analysis revealed that monocytes and dendritic cellscould interact with these cells and initiate phagocytosis via ICAM1-ITGAM and ITGB2 signaling.Together,our study systematically deciphered the detailed immunological response duringSARS-CoV-2 vaccination and infection.It may facilitate understanding the immune responseand the T-cell therapy against COVID-19. | Xiaojian Cao Xiaohua Chen Yaqi Zhu Xiaojuan Gou Keyi Yan Bing Yang Dong Men Lei Liu Yong-an Zhang Gang Cao | 2023 | Genes & Diseases2023,10,4: | 0 |