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| 1 | Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death显示文摘 | Jiang H Gomez-Manzano C Aoki H Alonso MM Kondo S McCormick F Xu J Kondo Y Bekele BN Colman H Lang FF Fueyo J | 2007 | 中国神经肿瘤杂志2007，5，3： | 24 |
| 2 | Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter?显示文摘AIM:To assess the outcome of patients with acute necrotizing pancreatitis treated by percutaneous drainage with special focus on the influence of drainage size and number. METHODS:We performed a retrospective analysis of 80 patients with acute pancreatitis requiring percutaneous drainage therapy for infected necroses. Endpoints were mortality and length of hospital stay. The influence of drainage characteristics such as the median drainage size, the largest drainage size per patient and the total drainage plane per patient on patient outcome was evaluated. RESULTS:Total hospital survival was 66%. Thirty-four patients out of all 80 patients (43%) survived acute necrotizing pancreatitis with percutaneous drainage therapy only. Eighteen patients out of all 80 patients needed additional percutaneous necrosectomy (23%). Ten out of these patients required surgical necrosectomy in addition, 6 patients received open necrosectomy without prior percutaneous necrosectomy. Elective surgery was performed in 3 patients receiving cholecystectomy and one patient receiving resection of the parathyroid gland. The number of drainages ranged from one to fourteen per patient. The drainage diameter ranged from 8 French catheters to 24 French catheters. The median drainage size as well as the largest drainage size used per patient and the total drainage area used per patient did not show statistically significant influence on mortality. CONCLUSION:Percutaneous drainage therapy is an effective tool for treatment of necrotizing pancreatitis.Large bore drainages did not prove to be more effective in controlling the septic focus. | T Bruennler J Langgartner S Lang CE Wrede F Klebl S Zierhut S Siebig F Mandraka F Rockmann B Salzberger S Feuerbach J Schoelmerich OW Hamer | 2008 | World Journal of Gastroenterology2008，14，5： | 23 |
| 3 | Colorectal anastomotic leakage: Aspects of prevention, detection and treatment显示文摘All colorectal surgeons are faced from time to time with anastomotic leakage after colorectal surgery. This complication has been studied extensively without a significant reduction of incidence over the last 30 years. New techniques of prevention, by innovative anastomotic techniques should improve results in the future, but standardization and 'teachability' should be guaranteed. Risk scoring enables intra-operative decision-making whether to restore continuity or deviate. Early detection can lead to reduction in delay of diagnosis as long as a standard system is used. For treatment options, no firm evidence is available, but future studies could focus on repair and saving of the anastomosis on the one hand or anastomotical breakdown and definitive colostomy on the other hand. | Freek Daams Misha Luyer Johan F Lange | 2013 | World Journal of Gastroenterology2013，19，15： | 11 |
| 4 | Integrated approach to colorectal anastomotic leakage: Communication, infection and healing disturbances显示文摘Colorectal anastomotic leakage(CAL) remains a major complication after colorectal surgery. Despite all efforts during the last decades, the incidence of CAL has not decreased. In this review, we summarize the available strategies regarding prevention, prediction and intervention of CAL and categorize them into three categories: communication, infection and healing disturbances. These three major factors actively interact during the onset of CAL. We aim to provide an integrated approach to CAL based on its etiology. The intraoperative air leak test, intraoperative endoscopy, radiological examinations and stoma construction mainly aim to detect and to prevent communication between the intra- and extra-luminal content. Other strategies including postoperative drainage, antibiotics, and infectious-parameter evaluation are intended to detect and prevent anastomotic or peritoneal infection. Most currently available interventions for CAL focus on the control of communication and infection, while strategies targeting the healing disturbances such as lifestyle changes, oxygen therapy and evaluation of metabolic biomarkers still lack wide clinical application. This simplified categorization may contribute to an integrated understanding of CAL. We strongly believe that this integrated approach should be taken into consideration during clinical practice. An integrated approach to CAL could contribute to a better understanding of the etiology of CAL and eventually better patient outcome. | Cloe L Sparreboom Zhou-Qiao Wu Jia-Fu Ji Johan F Lange | 2016 | World Journal of Gastroenterology2016，22，32： | 9 |
| 5 | 早发急性心肌梗死的长期结局和风险评估:10年随访研究显示文摘早发急性心肌梗死(acute myocardial infarction,AMI)是一种罕见的疾病,发病率和死亡率很高。该文在再灌注治疗广泛应用的大环境下,纳入前瞻性研究人群进行早发AMI的预后研究。方法:这项前瞻性多中心研究中连续纳入102例AMI存活者(≤40岁),临床预后通过奥地利死亡登记处和维也纳集中患者管理系统进行查询。 | 刘莉 叶鹏 Winter MP Blessberger H Alimohammadi A Pavo N Huber K Wojta J Lang IM Wiesbauer F Goliasch G | 2017 | 中华高血压杂志2017，25，4： | 5 |
| 6 | Functional significance of cell volume regulatory mechanisms显示文摘 | Lang F Busch GL Ritter M | 1998 | Physiol Rev1998，78，1： | 3 |
| 7 | Heterogeneous nucleating in the crystallization of polyolefins:Part 2 Kinetics of crystallization of nucleated polyolefins显示文摘 | Binsbergen F L De Lange B G M | 1970 | Polymer1970，11，6： | 2 |
| 8 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 9 | Powder processing science and technology for increased reliability 显示文摘 | LANGE F F | 1989 | J Am Ceram Soc1989，72，1： | 2 |
| 10 | Best Practices in Managing Investor Relations Websites: Directions for Future Research显示文摘 | Bollen Laury H Hassink Harold F de Lange Rindert K Buijl Saskia D | 2008 | Journal of Information Systems2008，，2： | 2 |
| 11 | Supernormal muscle fiber conduction velocity during intermittent isometric exercise in human muscle显示文摘 | Van der Hoeven JH Lange F | 1994 | J Appl Physiol1994，77，： | 1 |
| 12 | In vivo magnetic resonance imaging of iron oxide-1abeled, arterially-injected mesenchymal stem cells in kidneys of rats with acute ischemic kidney injury: detection and monitoring at 3T显示文摘 | Ittrich H Lange C Tgelo F | 2007 | J Magn Reson Imaging2007，25，6： | 1 |
| 13 | The suboccipital transcondylar approach to the clivus and cranio-cervical junction for ventrally placed pathology at and above the foramen magnum 显示文摘 | Neil-Dwyer G Iannotti F | 1995 | Acta Neurochir (Wein)1995，125，14： | 1 |
| 14 | Hydrothermal epitaxy of KTaO3 thin films显示文摘 | GOH G K L LEVI C G LANGE F F | 2002 | J Mater Res2002，17，11： | 1 |
| 15 | Processing-related fracture origins:Ⅱ agglomerate motion and crack-like internal surface caused by differential sintering 显示文摘 | LANG F F METCALF M | 1983 | J Am Ceram Soc1983，66，： | 1 |
| 16 | Separation of Eperythrozoon ovis from erythrocytes显示文摘 | Lang F M Ferrier G R Nicholls T J | 1986 | Vet Rec1986，119，： | 1 |
| 17 | Real ileal protein and amino acid digestibilities in feedsruffs for growing pigs as determined with the 15N-isotope dilution technique显示文摘 | de Lange C F M Souffrant W B Sauer W C | 1990 | J Anim Sci1990，68，： | 1 |
| 18 | C-Methyl-flavonoids from the leaf waxes of some Myrtaceae显示文摘 | Eckhard Wollenweber Rüdiger Wehde Marion D?rr Günter Lang Jan F Stevens | 2000 | Phytochemistry2000，，8： | 1 |
| 19 | The Reaction of a Phosphorus Ylide with Aroyl Cyanides显示文摘 | Soulen R L Carlson S D Lang F | 1973 | J Org Chem1973，38，3： | 1 |
| 20 | Restoring endodontically treated teeth with posts and cores显示文摘 | Peroz I Blankenstein F Lange K P | | 0，，09： | 1 |
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