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| 1 | Molecular diagnosis and therapy for occult peritoneal metastasis in gastric cancer patients显示文摘To apply an individualized oncological approach to gastric cancer patients,the accurate diagnosis of disease entities is required.Peritoneal metastasis is the most frequent mode of metastasis in gastric cancer,and the tumor-node-metastasis classification includes cytological detection of intraperitoneal cancer cells as part of the staging process,denoting metastatic disease.The accuracy of cytological diagnosis leaves room for improvement;therefore,highly sensitive molecular diagnostics,such as an enzyme immunoassay,reverse transcription polymerase chain reaction,and virusguided imaging,have been developed to detect minute cancer cells in the peritoneal cavity.Molecular targeting therapy has also been spun off from basic research in the past decade.Although conventional cytologyis still the mainstay,novel approaches could serve as practical complementary diagnostics to cytology in near future. | Shunsuke Kagawa Kunitoshi Shigeyasu Michihiro Ishida Megumi Watanabe Hiroshi Tazawa Takeshi Nagasaka Yasuhiro Shirakawa Toshiyoshi Fujiwara | 2014 | World Journal of Gastroenterology2014，20，47： | 11 |
| 2 | Endoscopic and radiographic features of gastrointestinal involvement in vasculitis显示文摘Vasculitis is an inflammation of vessel walls,followed by alteration of the blood flow and damage to the dependent organ.Vasculitis can cause local or diffuse pathologic changes in the gastrointestinal (GI) tract.The variety of GI lesions includes ulcer,submucosal edema,hemorrhage,paralytic ileus,mesenteric ischemia,bowel obstruction,and life-threatening perforation.The endoscopic and radiographic features of GI involvement in vasculitisare reviewed with the emphasis on small-vessel vasculitis by presenting our typicalcases,including Churg-Strauss syndrome,HenochSch nlein purpura,systemic lupus erythematosus,and Beh et's disease.Important endoscopic features are ischemic enterocolitis and ulcer.Characteristic computed tomographic findings include bowel wall thickening with the target sign and engorgement of mesenteric vessels with comb sign.Knowledge of endoscopic and radiographic GI manifestations can help make an early diagnosis and establish treatment strategy. | Akira Hokama Kazuto Kishimoto Yasushi Ihama Chiharu Kobashigawa Manabu Nakamoto Tetsuo Hirata Nagisa Kinjo Futoshi Higa Masao Tateyama Fukunori Kinjo Kunitoshi Iseki Seiya Kato Jiro Fujita | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，3： | 9 |
| 3 | Significance of hyperuricemia as a risk factor for developing ESRD in a screened cohort显示文摘 | Kunitoshi Iseki Yoshiharu Ikemiya Taku Inoue Chiho Iseki Kozen Kinjo Shuichi Takishita | 2004 | American Journal of Kidney Diseases2004，，4： | 4 |
| 4 | Blood Pressure Predicts Risk of Developing End-Stage Renal Disease in Men and Women显示文摘 | Masahiko Tozawa Kunitoshi Iseki Chiho Iseki Kozen Kinjo Yoshiharu Ikemiya Shuichi Takishita | 2003 | Hypertension: Journal of the American Heart Association2003，，6： | 2 |
| 5 | Chronic kidney disease: global dimension and perspectives显示文摘 | Vivekanand Jha Guillermo Garcia-Garcia Kunitoshi Iseki Zuo Li Saraladevi Naicker Brett Plattner Rajiv Saran Angela Yee-Moon Wang Chih-Wei Yang | 2013 | The Lancet2013，，9888： | 2 |
| 6 | Blood pressure predicts risk of developing end-stage renal disease in men and women 显示文摘 | Masahiko T Kunitoshi I Chiho I | 2003 | Hyperten- sion2003，41，： | 1 |
| 7 | Changes in the crystalline lens resultingfrom insertion of a phakic IOL (ICL)into the porcine eye显示文摘 | Kunitoshi Fujisawa Kimiya Shimizu Shigekazu Uga | | 0，，04： | 1 |
| 8 | Hyperuricemia and cardiovascular risk factor clustering in a screened cohort in Okinawa,Japan显示文摘 | KAZUFUMI N KUNITOSHI I TAKU I | | 0，，04： | 1 |
| 9 | CKD surveillance in japan 显示文摘 | Kunitoshi I | 2007 | Jpn J Nephrol2007，49，3： | 1 |
| 10 | Determination of Melamine and Three Hydrolytic Products by Liquid Chromatography显示文摘 | Takiko S Hajimu I Kunitoshi Y | 1990 | Bulletin of Environmental Contamination and Toxicology1990，44，4： | 1 |
| 11 | Hyperuricemia as a predictor of Hypertension in a screende cohort in Okinawa,Japan显示文摘 | Kazufumi Taku Inoue Kunitoshi Iseki | 2004 | Hypertension2004，27，： | 1 |
| 12 | Matrix metalloproteinase activity is enhanced during corneal wound repair in high glucose condition显示文摘 | Hiroshi Takahashi Kiyoshi Akiba Takayasu Noguchi Takeo Ohmura Ryoki Takahashi Youji Ezure Kunitoshi Ohara James D. Zieske | 2000 | Current Eye Research2000，，： | 1 |
| 13 | A Spring-guided Micropositioner with Linearized Sub-nanometer Resolution 显示文摘 | NISHIMURA Kunitoshi | 1991 | Review of Scientific Instruments1991，62，8： | 1 |
| 14 | Design, synthesis and structure-activity relationships of 5-alkylaminolquinolines as a novel series of CRF1 receptor antagonists显示文摘 | Kunitoshi T Taro T Kogyoku S | 2012 | Bio Med Chem2012，22，： | 1 |
| 15 | Late‐evening snack with branched‐chain amino acids improves liver function after radiofrequency ablation for hepatocellular carcinoma显示文摘 | Daisuke Morihara Kaoru Iwata Takayuki Hanano Hideo Kunimoto Shizuka Kuno Atsushi Fukunaga Kaoru Yotsumoto Kazuhide Takata Takashi Tanaka Kunitoshi Sakurai Hideyuki Iwashita Shu‐ichi Ueda Genryu Hirano Keiji Yokoyama Hidetoshi Nakane Shinya Nishizawa Makot | 2012 | Hepatology Research2012，，7： | 1 |
| 16 | Coronary Artery Calcification in Patients on Chronic Hamodialysis:Evaluation by Electron Beam Computed Tomography显示文摘 | Kunitoshi Iseki | 2006 | Therapeutic Apheresis and Dialysis2006，10，1： | 1 |
| 17 | Higher Heart Rate Predicts the Risk of Developing Hypertension in a Normotensive Screened Cohort显示文摘 | Taku Inoue Kunitoshi lseki Chiho Iseki | 2007 | Circ J2007，71，： | 1 |
| 18 | Blood pressure predicts risk of developing end-stage renal disease in men and women显示文摘 | Masahiko T Kunitoshi I Chiho I | 2003 | Hypertension2003，41，： | 1 |
| 19 | Prevalence of high fasting plasma glucose and risk of developing end-stage renal disease in screened subjects in Okinawa, Japan显示文摘 | Kunitoshi Iseki Yoshiharu Ikemiya Kozen Kinjo Chiho Iseki Shuichi Takishita | 2004 | Journal of Clinical and Experimental Nephrology2004，，3： | 1 |
| 20 | 显示文摘 | TAKIKO S HAJIMU I KUNITOSHI Y | 1990 | Bulletin of Environmental Contamination and Toxicology1990，44，4： | 1 |
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