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| 1 | Clinical outcomes of enteroscopy using the double-balloon method for strictures of the small intestine显示文摘AIM: To evaluate the clinical outcome of enteroscopy, using the double-balloon method, focusing on the involvement of neoplasms in strictures of the small intestine.METHODS: Enteroscopy, using the double-balloon method, was performed between December 1999 and December 2002 at Jichi Medical School Hospital, Japan and strictures of the small intestine were found in 17 out of 62 patients. These 17 consecutive patients were subjected to analysis.RESULTS: The double-balloon enteroscopy contributed to the diagnosis of small intestinal neoplasms found in 3out of 17 patients by direct observation of the strictures as well as biopsy sampling. Surgical procedures were chosen for these three patients, while balloon dilation was chosen for the strictures in four patients diagnosed with inflammation without involvement of neoplasm.CONCLUSION: Double-balloon enteroscopy is a useful method for the diagnosis and treatment of strictures in the small bowel. | Keijiro Sunada Hironori Yamamoto Hiroto Kita Tomonori Yano Hiroyuki Sato Yoshikazu Hayashi Tomohiko Miyata Yutaka Sekine Akiko Kuno Michiko Iwamoto Hirohide Ohnishi Kenichi Ido Kentaro Sugano | 2005 | World Journal of Gastroenterology2005，11，7： | 6 |
| 2 | Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy显示文摘AIM: To clarify clinical features of the NSAID-induced small bowel lesions using a new method of endoscopy.METHODS: This is a retrospective study and we analyzed seven patients with small bowel lesions while taking NSAIDs among 61 patients who had undergone doubleballoon endoscopy because of gastro-intestinal bleeding or anemia between September 2000 and March 2004, at Jichi Medical School Hospital in Japan. Neither conventional EGD nor colonoscopy revealed any lesions of potential bleeding sources including ulcerations. Double-balloon endoscopy was carried out from oral approach in three patients, from anal approach in three patients, and from both approaches in one patient.RESULTS: Ulcers or erosions were observed in the ileum in six patients and in the jejunum in one patient, respectively.The ulcers were multiple in all the patients with different features from tiny punched out ulcers to deep ulcerations with oozing hemorrhage or scar. All the patients recovered uneventfully and had full resolution of symptoms after suspension of the drug.CONCLUSION: NSAIDs can induce injuries in the small bowel even in patients without any lesions in both the stomach and colon. | Yoshikazu Hayashi Hironori Yamamoto Hiroto Kita Keijiro Sunada Hiroyuki Sato Tomonori Yano Michiko Iwamoto Yutaka Sekine Tomohiko Miyata Akiko Kuno Takaaki Iwaki Yoshiyuki Kawamura Hironari Ajibe Kenichi Ido Kentaro Sugano | 2005 | World Journal of Gastroenterology2005，11，31： | 6 |
| 3 | Full-length sequencing and genomic characterization of Bagaza, Kedougou, and Zika viruses显示文摘 | G. Kuno G.-J. J. Chang | 2007 | Archives of Virology2007，，4： | 5 |
| 4 | CCR5 gene expression in fulminant hepatitis and DTH in mice显示文摘CCR5geneexpressioninfulminanthepatitisandDTHinmiceGUOBaoYu1,ZHANGSuYing2,NaofumiMukaida3,AkihisaHarada3,KoujiKuno3,WANGJian... | GUO Bao-Yu ZHANG Su-Ying Naofumi Mukaida Akihisa Harada Kouji Kuno WANG Jian-Bin SUN Shu-Han Kouji Matsushima | 1998 | World Journal of Gastroenterology1998，4，1： | 5 |
| 5 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 6 | Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases显示文摘 | Hironori Yamamoto Hiroto Kita Keijiro Sunada Yoshikazu Hayashi Hiroyuki Sato Tomonori Yano Michiko Iwamoto Yutaka Sekine Tomohiko Miyata Akiko Kuno Hironari Ajibe Kenichi Ido Kentaro Sugano | 2004 | Clinical Gastroenterology and Hepatology2004，，11： | 2 |
| 7 | Customer orientation in electronic government: Motives and effects显示文摘 | Kuno Schedler Lukas Summermatter | 2006 | Government Information Quarterly2006，，2： | 2 |
| 8 | Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation显示文摘 | Masayoshi Ohta Yoshihisa Suzuki Toru Noda Yoko Ejiri Mari Dezawa Kazuya Kataoka Hirotomi Chou Namiko Ishikawa Naoya Matsumoto Yasushi Iwashita Eiji Mizuta Sadako Kuno Chizuka Ide | 2004 | Experimental Neurology2004，，2： | 2 |
| 9 | Assessment of voiding dysfunction in Parkinson's disease by the international prostate symptom score 显示文摘 | Araki I Kuno S | 2000 | Neurol Neurosurg Psychiatry2000，68，： | 1 |
| 10 | The growth,maturation and feeding habits of the gobiid fish Acanthogobius hasta distribution in Ariake Sound,Kyushu,Japan显示文摘 | KUNO Y TAKITA T | 1997 | Fisheries Science1997，63，： | 1 |
| 11 | Matrix metalloproteinas- es 2 and 9 in oral squamous cell carcinomas: manifesta- tion and localization of their activity显示文摘 | Kato K Hara A Kuno T | 2005 | J Cancer Res Clin Oncol2005，131，6： | 1 |
| 12 | Mathematical models for predator prey interaction 显示文摘 | Kuno E | 1987 | Advance in Ecological Research1987，16，2： | 1 |
| 13 | Endocannabinoids as car diovascular modulators 显示文摘 | Kunos G Jarai Z Batkai S | 2000 | Chem Phys Lipids2000，108，15： | 1 |
| 14 | Recent advancement in fla vivirus vaccine development显示文摘 | Chang G J Kuno G Purdy D E | 2004 | Exp Rev Vaccines2004，3，2： | 1 |
| 15 | Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and (L)-dopa-undertreated Parkinson disease: a double-blind, randomized trial显示文摘 | Mizuno Y Yamamoto M Kuno S | 2012 | Clin Neuropharma- col2012，35，4： | 1 |
| 16 | Occurrence of Fusarium wilt caused by Fusarium oxysporum in balsam pears in Miyazaki, Ja- pan and analysis of the pathogen based on the rDNA IGS sequence 显示文摘 | Imamura Y Kawagoe Y Kuno K | 2007 | Kyushu Plant Protection Research2007，53，： | 1 |
| 17 | Postural control respon- ses sitting on unstable board during visual stimulation 显示文摘 | Mizuno Y Shindo M Kuno S | 2001 | Acta Astronaut2001，49，310： | 1 |
| 18 | Cycloprodigiosin hydrochloride, a new H+/Cl- sympoter,induces apoptosis in human and rat hepatocellular cancer cell line in vitro and inhibits yhe growth of hepatocellular carcinoma xenografts in nude mice显示文摘 | Takemoto H Kuno K Yamamoto D Tsubura A Kamata H | 1999 | Hepatology1999，30，4： | 1 |
| 19 | Statistical analysis of field data of railway noise and vibration collected in an urban area显示文摘 | Okaumura Y Kuno K | 1991 | Applied Acoustics1991，33，4： | 1 |
| 20 | Glutathione-S-transferase and interleukin-1 beta gene polymorphisms in Japanese patients with Parkinson's disease显示文摘 | Nishimura M Kuno S Kaji R | 2005 | Mov Disord2005，20，7： | 1 |
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