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| 1 | Antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis显示文摘Objective:To explore antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis(A.officinalis).Methods:In the present study the leaf extracts of A.officinalis were examined for its antibacterial potential using five different solvents against some reference strains of human pathogenic bacteria for the crude extract.Maximum activity was observed for ethyl acetate and hence different concentrations like 15μL,25μL,and 50μL of ethyl extracts was checked for its antibacterial activity.Partial purification of crude extract was carried by column chromatography and fractions were analyzed using gas chromatography-mass spectrometry(GC-MS) to identify compounds.Results:The crude ethyl acetate extracts of A.officinalis showed remarkable antibacterial activity with zones of inhibition of 13 mm against Eschericia coli(E.coli) and 11 mm against Staphylococcus aureus (S.aureus).Fraction 13(ethyl acetate:methanol= 8:2) as the most potent one against with the minimal inhibitory concentration of 30 mm against E.coli and 25 mm against S.aureus.The GCMS resultsof active column fraction(F13) revealed that the active principals were a mixture of hydroxy- 4 methoxybenzoic acid,diethyl phthalate,oleic acid.Conclusions:The leaf extracts with proven antibacterial effects can clearly be directed towards cancer treatment as to inhibiting cancer cell growth.The limited number of test organisms owes to a constraint of resource.So,the effect of strong bursts of leaf extracts on human pathogenic bacteria should further be tested on a wide range of test organisms. | Valentin Bhimba B J Meenupriya Elsa Lycias Joel D Edaya Naveena Suman kumar M Thangaraj | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 13 |
| 2 | Efficient and convenient polyethylene glyeol(PEG)-mediated synthesis of spiro-oxindoles显示文摘 | Meshram H M Kumar D A Prasad B R V | 2010 | Helvetica Chimica ACTA2010，93，4： | 1 |
| 3 | Phytoremediation:anovel strategy for the removal of toxic metals from the environment using plants显示文摘 | SALT D E BLAYLOCK M KUMAR N P B A | 1995 | Nature Biotechnology1995，13，5： | 1 |
| 4 | Ontogenetic development of digestive enzymes in yellowtail kingfish Seriola lalandi larvae 显示文摘 | Chen B N Qin J G Kumar M S | 2006 | Aquaculture2006，260，： | 1 |
| 5 | Toxin productionby Curvularia lunata of grain discoloration disease in rice显示文摘 | PATIL B PATIL M B KUMAR C | 2014 | Environment and Ecology2014，32，4： | 1 |
| 6 | Changes in sleep-wakefulness in the medial preoptic area lesioned rats:role of thermal preference显示文摘 | Ray B Mallick H N Kumar V M | 2005 | Behav Brain Res2005，158，1： | 1 |
| 7 | Experimental quantifi- cation of chemical effects of hydrodynamic cavitation 显示文摘 | Senthil Kumar P Siva Kumar M Pandit A B | 2000 | Chemical Engineering Science2000，55，9： | 1 |
| 8 | Rigid nasal en- doscopy in the diagnosis and treatment of epistaxis 显示文摘 | Kumar M V V Prasad K U R Gowda P R B | 2013 | J Clin Diagn Res2013，7，5： | 1 |
| 9 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 10 | Nasogastric and percutaneous endoscopic gastrostomy tube use in advanced head and neck cancer patients:a comparative study显示文摘 | SADASIVAN A FAIZAL B KUMAR M | 2012 | J Pain Palliat Care Pharmacother2012，26，： | 1 |
| 11 | Experimentalquantifi-cation of chemical effects of hydrodynamic cavitation显示文摘 | Kumar P Senthil Kumar M Siva Pandit A B | 2000 | ChemicalEngineering Science2000，55，9： | 1 |
| 12 | Darcy free convection induced by a vertical wavy surface in a thermally stratified porous medium显示文摘 | Rathish Kumar B V Shalini M | 2004 | International Journal of Heat Mass Transfer2004，47，： | 1 |
| 13 | Design and fabrication of an automated technique: measurement of spontaneous polarization in two new schiff'base ferroelectric liquid crystals 显示文摘 | Madhu Mohan M L N Goud B V S Kumar P A | 1999 | Materials Research Bulletin1999，34，1415： | 1 |
| 14 | Agroforestry as sequestration 显示文摘 | Nair P K R Kumar B M a strategyfor carbon Nair V D | 2009 | Journal of Plant Nutrition and Soil Science2009，172，： | 1 |
| 15 | The nucleocapsid protein of the SARS coronavirus is capable of self-association through a C-terminal 209 amino acid interaction domain显示文摘 | Surjit M Liu B Kumar P | 2004 | Biochem Biophys Res Commun2004，317，4： | 1 |
| 16 | Numerical Studies of a Tube - in - tube Helically Coiled Heat Ex- changer 显示文摘 | KUMAR V FAIZEE B MRIDHA M | 2008 | Chemical Engineering and Processing2008，47，12： | 1 |
| 17 | Evaluation of cognitive function of fluoxetine,sertraline and tianeptine in isolation and chronic unpredictable mild stress-induced depressive Wistar rats显示文摘 | Ramanathan M Kumar SN Suresh B | | 0，，11： | 1 |
| 18 | De- velopment of Al-Ti-C grain refiners and study of their grain refining efficiency on Al and Al-7Si alloy显示文摘 | KUMAR G SjMURTY B S CHAKROABTHY M | 2005 | Journal of Alloys and Compounds2005，396，12： | 1 |
| 19 | Molecular regulation of vascular smooth muscle cell differentiation development and disease显示文摘 | OWEN G K KUMAR M S WAMHOFF B R | 2004 | Physiol Rev2004，84，3： | 1 |
| 20 | The gap junction communication channel显示文摘 | Nalin M kumar Norton B | 1996 | Cell1996，84，： | 1 |
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