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| 1 | Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway.显示文摘 | Chert J Tang XQ Zhi JL Cui Y Yu HM Tang EH Sun SN Feng JQ Chen PX Chen J | 2006 | 中国生物学文摘2006，20，10： | 16 |
| 2 | 内脏脂肪组织通过产生骨桥蛋白调控成纤维细胞衰老促进心脏衰老显示文摘老化通过增加包括骨桥蛋白(osteopontin,OPN)在内的细胞外基质(extracellular matrix,ECM)蛋白的沉积引起心脏结构和功能改变进而导致进行性间质纤维化。虽然已知OPN参与各种病理状况,但其在心肌衰老中的作用仍不清楚。 | Sawaki D Czibik G Pini M Ternacle J Suffee N Mercedes R Marcelin G Surenaud M Marcos E Gual P Clément K Hue S Adnot S Hatem SN Tsuchimochi I Yoshimitsu T Hénégar C Derumeaux G 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，3： | 14 |
| 3 | 干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用: | Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，8： | 9 |
| 4 | Lack of Efficacy of Bevacizumab Plus Irinotecan in Children with Recurrent Malignant Glioma and Diffuse Brainstem Glioma:A Pediatric Brain Tumor Consortium Study显示文摘PURPOSE:A phase Ⅱ study of bevacizumab(BVZ) plus irinotecan(CPT-11) was conducted in children with recurrent malignant glioma(MG) and intrinsic brainstem glioma(BSG).PATIENTS AND METHODS:Eligible patients received two doses of BVZ | Gururangan S Chi SN Young Poussaint T Onar-Thomas A Gilbertson RJ Vajapeyam S Friedman HS Packer RJ Rood BN Boyett JM Kun LE | 2010 | 中国神经肿瘤杂志2010，8，2： | 7 |
| 5 | Seroepidemiology of Helicobacter pylori infection among asymptomatic Chinese children显示文摘INTRODUCTIONIncreasing data has demonstrated that Helicobacterpylori(H.pylori),a spiral gram negativebacterium,colonized in human stomach,can causetype B gastritis,is strongly associated withgastric and duodenal ulceration,and has beenimplicated in the causation of gastric carcinomaand mucosa-associated lymphoid tissue(MALT)lymphomas.It has been reported that there | Xu CD Chen SN Jiang SH Xu JY | 2000 | World Journal of Gastroenterology2000，6，5： | 6 |
| 6 | Escherichia coli tetracycline efflux determinants in relation to tetracycline residues in chicken显示文摘Objective:To screen for Escherichia coli(E.coli)resistant to tetracycline,followed by identification of tet efflux genes by polymerase chain reaction(PCR).In addition,detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mass spectrometry(HPLC-MS-MS).Methods:Strains of E.coli were isolated from samples of chicken colon and screened for tetracycline resistance.Tetracycline genes conferring resistance(Tc^r)were detected by polymerase chain reaction(PCR).Most of the isolates were resistant to tetracycline(97.9%).Results:PCR analysis indicated that Tc^r E.coli R-plasmids contained tet(A),tet(B)and a combination of both efflux genes.None of the isolates contained other efflux tet genes tet(C,D,E and Y).High performance liquid chromatography-tandem quadrupole mass spectrometry(HPLC-MS-MS),a sensitive technique,was used to detect residues of chlortetracycline(CTC),oxytetracyeline(OTC),doxveycline(DC)in chicken livers and kidneys.The samples containing tetracycline residues were at 0.13-0.65pg/μL levels.Conclusions:Tetracycline and other antibiotics are commonly used in the poultry and meat production industry for prevention of microbial infections.Multiple antibiotic resistant bacteria in Oman have increased to alarming levels,threatening public health,domestic and may have adverse effect on environment. | Al-Bahry SN Al-Mashani BM Al-Ansari AS Elshafie AE Mahmoud IY | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，9： | 4 |
| 7 | 以天然沥青岩为原料制备高压缩强度的泡沫炭(英文)显示文摘以安纳托利亚东南部的天然沥青岩为原料制备泡沫炭。所制泡沫炭的平均孔径和密度分别为150μm和800 kg/m3。主要研究了压力、温度、泄压时间及在最高温度时的停留时间对泡沫形成的影响,同时还评价了炭化过程对泡沫结构的影响。主要研究了压力、温度、泄压时间及在最高温度时的停留时间对泡沫炭进行了表征,并进行了密度及抗压强度分析。结果表明,1 323 K炭化后,泡沫炭压缩强度由10 MPa增加到18.7 MPa。沥青的灰分含量(41.76%)对泡沫炭的密度和压缩强度起重要作用。 | Deniz Baran Mehmet Ferhat Yardim Hüsnü Atakül Ekrem Ekinci | 2013 | 新型炭材料2013，28，2： | 4 |
| 8 | Slower cycling of nestin-positive cells in neurosphere culture显示文摘 | Ma BF Liu XM Xie XM Zhang AX Zhang JQ Yu WH Zhang XM Li SN Lahn BT Xiang AP | 2006 | 中国生物学文摘2006，20，5： | 4 |
| 9 | Gene splicing by overlap extention:tailor-made genes using the polymerase chain reaction显示文摘 | Horton RM Cai ZL Ho SN | 1990 | Biotechniques1990，8，5： | 2 |
| 10 | Infliximab therapy in patients with ankylosing spondylitis: an open label 12 month study显示文摘 | Temekonidis TI Alamanos Y Nikas SN | 2003 | Ann Rheum Dis2003，62，12： | 2 |
| 11 | Dynamic role of myofibroblasts in oral lesions显示文摘Fibroblasts are the most abundant cellular components of connective tissue. They possess phenotypical heterogenicity and may be present in the form of smooth muscle cells or myofibroblasts(MFs). MFs are spindle-shaped cells with stress fibres and welldeveloped fibronexus,and they display α-smooth muscle actin immunohistochemically and smoothmuscle myofilaments ultrastructurally. MFs play a crucial role in physiological and pathological processes. Derived from various sources,they play pivotal roles not only by synthesizing and producing extracellular matrix components,such as other connective tissue cells,but also are involved in force production. In the tissue remodelling phase of wound closure,integrinmediated interactions between MFs and type I collagen result in scar tissue formation. The tumour stroma in oral cancer actively recruits various cell types into the tumour mass,where they act as different sources of MFs. This article reviews the importance of MFs and its role in pathological processes such as wound healing,odontogenic cysts and tumours,salivary gland tumours,oral preneoplasia,and oral squamous cell carcinoma. Research oriented on blocking the transdifferentiation of fibroblasts into MFs can facilitate the development of noninvasive therapeutic strategies for the treatment of fibrosis and/or cancer. | Neeta Bagul Anjali Ganjre SN Goryawala Rahul Kathariya Shrikant Dusane | 2015 | World Journal of Clinical Oncology2015，6，6： | 2 |
| 12 | TWO NORDITERPENOID ALKALOIDS FROM ACONITUM LEUCOSTOMUM显示文摘TWO NORDITERPENOID ALKALOIDS FROM ACONITUM LEUCOSTOMUMTWONORDITERPENOIDALKALOIDSFROMACONITUMLEUCOSTOMUM￥JianMinYUE;JunXUandHa... | Yue, JM Xu, J Sun, HD Chen, SN Chen, YZ | 1996 | Chinese Chemical Letters1996，7，8： | 2 |
| 13 | NF-AT components define a family of transcription factors targeted in T-cell activation显示文摘 | Northrop JP Ho SN Chen L | 1994 | Nature1994，369，6480： | 2 |
| 14 | 肥胖Zucker大鼠肾脏血管紧张素Ⅱ2型受体及Mas受体共定位,且功能相互依赖显示文摘血管紧张素Ⅱ2型受体(angiotensinⅡtype 2receptor,AT_2R)与Mas受体(the receptor Mas,MasR)作用复杂,但均具有相似的前利钠作用,尤其是在肥胖/糖尿病大鼠肾脏中AT_2R表达及利钠作用增强。根据一些报道提示的这些受体之间的潜在正相互作用,研究者在肥胖大鼠中验证肾脏AT_2R及MasR生理上相互作用、相互依赖地刺激细胞信号转导及促进利钠作用的假设。 | Patel SN Ali Q Samuel P Steckelings UM Hussain T 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 15 | Lymph node staging of bladder neck carcinoma with positron emission tomography显示文摘 | Bachor R Kotzerke J Reske SN | 1999 | Urologe A1999，38，： | 2 |
| 16 | 骨密度变化可作为抗骨折治疗效果的预测指标显示文摘骨质疏松症伴骨折对个人及社会均造成沉重负担,双能X线评定骨密度是目前诊断骨质疏松症的金标准。本研究旨在探究在临床实践中,常规骨密度检测作为骨折风险干预预测指标的效果。自1997年,加拿大曼尼托巴省便对本省年龄大于65岁的老年女性或者存在其它骨折风险的年轻女性进行常规的骨密度检查。研究者对大多数患者进行三年随访,而对有低骨折风险患者则进行至少为期5年的随访。数据显示,年龄大于或等于40岁的女性完成了至少一次的随访检查。 | Leslie WD Majumdar SR Morin SN 何成奇 | 2017 | 中国康复2017，32，1： | 2 |
| 17 | Morphological appearance of the healing corneal endothelium 显示文摘 | Rao SN Shaw EL Arthur E | 1978 | Arch Ophthalmol1978，96，10： | 2 |
| 18 | 表面处理对瓷牙材料机械强度影响的实验研究显示文摘目的 比较不同表面处理因素对瓷牙材料机械强度的影响。方法 制备 30 0个表面均匀一致的实验标本 ,对抛光面进行表面处理 ,处理后的标本用万能实验机进行机械循环 ,然后用Piston on threeball方法检查实验标本的挠屈强度。结果 双向卡方检验说明不同表面处理因素及不同循环次数对实验标本挠屈强度的影响都具有显著意义 (P <0 .0 0 0 1) ;Q 检验说明自然上釉、酸蚀、喷砂等表面处理和表面抛光相比 ,可以降低实验标本的挠屈强度 (P <0 .0 5 ) ,而离子交换可以增加瓷牙材料的挠屈强度 (P <0 .0 5 )。 结论 瓷牙材料表面经离子交换后可以增加其强度 ,自然上釉、酸蚀、喷砂等表面处理过程可以降低瓷牙材料的机械强度。 | 李振春 White SN | 2000 | 口腔材料器械杂志2000，9，2： | 2 |
| 19 | 用体外心内膜赘生物模型评价万古霉素和达托霉素对甲氧西林耐药金葡菌和异质性万古霉素中介金葡菌的抗菌活性显示文摘 | Leonard SN Rybak MJ 袁瑾懿 王明贵 | 2010 | 中国感染与化疗杂志2010，10，3： | 2 |
| 20 | Fommtion of steady-state oxygen gradients in vic ID : application to liver zonation 显示文摘 | Allen JW Bhatia SN | 2003 | Biotechnol Bioeng2003，82，3： | 1 |
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