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| 1 | Multiple metastases to the small bowel from large cell bronchial carcinomas显示文摘AIM: Metastases from lung cancer to gastrointestinal tract are not rare atpostmortem studies but the development of clinically significant symptoms from the gastrointestinal metastases is very unusual.METHODS: Formalin-fixed, paraffin-embedded tissues were cut into 5 μm thick sections and routinely stained with hematoxylin and eosin. Some slides were also stained with Alcian-PAS. Antibodies used were primary antibodies to pancytokeratin, cytokeratin 7, cytokeratin 20, epithelial membrane antigen, vimentin, smooth muscle actin and CD-117.RESULTS: We observed three patients who presented with multiple metastases from large cell bronchial carcinoma to small intestine. Two of them had abdominal symptoms (sudden onset of abdominal pain, constipation and vomiting) and in one case the tumor was incidentally found during autopsy. Microscopically, all tumors showed a same histological pattern and consisted almost exclusively of strands and sheets of poorly cohesive, polymorphic giant cells with scanty, delicate stromas. Few smaller polygonal anaplastic cells dispersed between polymorphic giant cells,were also observed. Immunohistochemistry showed positive staining of the tumor cells with cytokeratin and vimentin. Microscopically and immunohistochemically all metastases had a similar pattern to primary anaplastic carcinoma of the small intestine.CONCLUSION: In patients with small intestine tumors showing anaplastic features, especially with multiple tumors, metastases from large cell bronchial carcinoma should be first excluded, because it seems that they are more common than expected. | Davor Tomas Mario Ledinsky Mladen Belicza Bozo Kru(s|ˇ)lin | 2005 | World Journal of Gastroenterology2005，11，9： | 4 |
| 2 | Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors显示文摘 | Daniela C. Kroy Donatella Ciuffreda Jennifer H. Cooperrider Michelle Tomlinson Garrett D. Hauck Jasneet Aneja Christoph Berger David Wolski Mary Carrington E. John Wherry Raymond T. Chung Kenneth K. Tanabe Nahel Elias Gordon J. Freeman Rosemarie H. de Kru | 2014 | Gastroenterology2014，，2： | 2 |
| 3 | Source apportionment of elevated wintertime PAHs by compound-specific radiocarbon analysis显示文摘 | Sheesley R J Kruså M Krecl P | 2009 | Atmospheric Chemistry and Physics2009，9，10： | 1 |
| 4 | Height restoration andmaintenance after treating unstable osteoporotic vertebral compressionfractures by cement augmentation is dependent on the cement volumeused显示文摘 | KrU ger A Baroud G Noriega D | 2013 | Clinical Biomechanics2013，28，7： | 1 |
| 5 | Fast pipeline models for simulation of hydraulic systems 显示文摘 | Krus P Weddfel K Palmberg J | 1994 | Journal of Dynamic Systems Measurement and Control of the ASME1994，116，3： | 1 |
| 6 | Hight-Pressure Well Design 显示文摘 | Harrle Krus Jean-Marle Prleur | 1991 | Drilling Engineering1991，，12： | 1 |
| 7 | Prerenting wound infection after appendectomy显示文摘 | Kru KO Wski ZH | 1998 | Bd Sury1998，25，10： | 1 |
| 8 | Prerenting wound infection after appendectomy显示文摘 | Kru KO Wski ZH | 1998 | BrI Sury1998，25，： | 1 |
| 9 | Economic growth and the environment显示文摘 | GROSSMAN KRU EGER | | 0，，112： | 1 |
| 10 | Silencing of microRNAs in vivo with antagomirs 显示文摘 | Kru tzfeldt J Rajewsky N Braich R | 2005 | Nature2005，438，7068： | 1 |
| 11 | Synthesis and Characterization of Structurally Uniform Model Oligomers of Polybenzoxazine显示文摘 | H Ishida C M Krus | 1998 | Macromolecules1998，31，8： | 1 |
| 12 | Anatomy of the medial femoral circumflex artery and its surgical implications 显示文摘 | Gautier E Ganz K Kru gel N | 2000 | J Bone Joint Surg Br2000，82，5： | 1 |
| 13 | Central nervoussystem mechanisms in Sjogren syndrome 显示文摘 | Van Bijsterveld OP Kru ize AA Bleys RLA | 2003 | Br J Ophthalmol2003，87，： | 1 |
| 14 | Cooperative game solution concepts to a cost allocation problem显示文摘 | Kru? L Bronis P | 2000 | European Journal of Operational Research2000，122，2： | 1 |
| 15 | Computerized optimization of selectivity for direct capillary gas chromatographic multicomponent separations of enantiomers显示文摘 | KRU PCIK J GRENA M | 1997 | J Chromat A1997，779，： | 1 |
| 16 | Cooperative Game Solution Concepts to a Cost Allocation Problem显示文摘 | Lech Krus Piotr Bronisz | 2000 | European Journal of Operational Research2000，122，： | 1 |
| 17 | MxA-independent inhibition of Hantaan virus replication induced by type 1 and type II interferon in vitro显示文摘 | Oelschlegel R Kru ger D Rang A | 2007 | Virus Res2007，127，1： | 1 |
| 18 | Specificity, duplex degra- dation and subcellular localization of antagomirs 显示文摘 | Kru tzfeldt J Kuwajima S Braich R | 2007 | Nucleic Acids Res2007，35，9： | 1 |
| 19 | Synthesis and characterization of structurally uniform model oligomers of poly- benzoxazine 显示文摘 | Ishida H Krus C M | 1998 | nacromolecules1998，31，8： | 1 |
| 20 | Light and electron microscopic picture of atherosclertic plaque in stable and unstable angina显示文摘 | Walczak E Krus S Fiejka E | 1999 | Pol J Pathol1999，50，： | 1 |
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