|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bilateral symmetrical periprosthetic (mirror) fractures of knee fixed with dual plating tech- nique显示文摘 | Gurava RV Krishna MA Chiranjeevi T | 2011 | Int J Surg Case Rep2011，2，7： | 1 |
| 2 | HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation显示文摘Group 2 innate lymphoid cells(ILC2s)are a category of heterogeneous cells that produce the cytokines IL-5 and IL-13,which mediate the type 2 immune response.However,specific drug targets on lung ILC2s have rarely been reported.Previous studies have shown that type 2 cytokines,such as IL-5 and IL-13,are related to depression.Here,we demonstrated the negative correlation between the depression-associated monoamine neurotransmitter serotonin and secretion of the cytokines IL-5 and IL-13 by ILC2s in individuals with depression.Interestingly,serotonin ameliorates papain-induced lung inflammation by suppressing ILC2 activation.Our data showed that the serotonin receptor HTR2A was highly expressed on ILC2s from mouse lungs and human PBMCs.Furthermore,an HTR2A selective agonist(DOI)impaired ILC2 activation and alleviated the type 2 immune response in vivo and in vitro.Mice with ILC2-specific depletion of HTR2A(Il5^(cre/+)·Htr2a^(flox/flox)mice)abolished the DOI-mediated inhibition of ILC2s in a papain-induced mouse model of inflammation.In conclusion,serotonin and DOI could restrict the type 2 lung immune response,indicating a potential treatment strategy for type 2 lung inflammation by targeting HTR2A on ST2+ILC2s. | Zhishuo Wang Chenghua Yan Qizhen Du Yuying Huang Xuezhen Li Dan Zeng Ruizhi Mao Rama Krishna Gurram Shipeng Cheng Wangpeng Gu Lin Zhu Weiguo Fan Liyan Ma Zhiyang Ling Ju Qiu Dangsheng Li Enmei Liu Yaguang Zhang Yiru Fang Jinfang Zhu Bing Sun | 2023 | Cellular & Molecular Immunology2023，20，4： | 1 |
| 3 | Effect of CYP2C9, VKORC1, CYP4F2 and GGCX genetic variants on warfarin maintenance dose and explicating a new pharmacogenetic algorithm in South Indian population显示文摘 | Krishna Kumar D Shewade DG Loriot MA | 2014 | Eur J Clin Pharmacol2014，70，1： | 1 |
| 4 | Utility of B-natriuretic peptide in detecting diastolic dysfunction 显示文摘 | Lubien E De MA Krishnas WP | 2002 | Circulation2002，105，8： | 1 |
| 5 | Effects of oral posa- conzole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers显示文摘 | KRISHNA G MOTON A MA L | 2009 | J Acquir Immune Defic Syndr2009，51，4： | 1 |
| 6 | Adhesion and debonding of multilayer thin film structures显示文摘 | Dauskardt R H Lane M Ma Q Krishna N | 1998 | Engineering Fracture Mechanics1998，61，1： | 1 |
| 7 | Pharmacokinetics of asingle dose of the antifungal posaconazole as oral suspension insubjects with hepatic impairment 显示文摘 | MOTON A KRISHNA G MA L | 2010 | Cun Med Res Opin2010，26，1： | 1 |
| 8 | Synthesis and diels-Alder cycloaddition reactions of benzene and benzene显示文摘 | Sridhar M Krishna K L Rao J Ma | 2000 | l''etrahedron2000，56，22： | 1 |
| 9 | Contemporary long-term outcomes of an aggressive approach to mitral valve repair in children :is it effective and durable for both eongenital and acquired mi- tral valve lesions? 显示文摘 | Yakub MA Krishna Moorthy PS Sivalingam S | 2015 | Eur J Cardiothorac Surg2015，，： | 1 |
| 10 | Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial显示文摘 | M Adjuik P Agnamey A Babiker S Borrmann P Brasseur M Cisse F Cobelens S Diallo JF Faucher P Garner S Gikunda PG Kremsner S Krishna B Lell M Loolpapit P-B Matsiegui MA Missinou J Mwanza F Ntoumi P Olliaro P Osimbo P Rezbach E Some WRJ Taylor | 2002 | The Lancet2002，，9315： | 1 |
| 11 | Is rheumatic aetiology a predictor of poor outcome in the current era of mitral valve repair Contemporary long-term results of mitral valve repair in rheumatic heart disease显示文摘 | Yakub MA Dillon J Krishna Moorthy PS | | 0，，： | 1 |
| 12 | Adhesion and debonding of multi-layer thin film structures 显示文摘 | Dauskardt R H Lane M Ma Q Krishna N | 1998 | Engineering fracture mechanics1998，61，： | 1 |
| 13 | Is rheumatic aetiology a predictor of poor outcome in the current era of mitral valve repair? Contemporary |ang-term results of mitral valve repair in rheumatic heart disease 显示文摘 | Yakub MA Dillon J Krishna MPS | 2013 | Eur J Cardiothorac Surg2013，44，4： | 1 |
| 14 | Laparoscopic sleeve mastectomy:standardized technique of a potential stand- alone bariatrie procedure in morbidly obese patients显示文摘 | Keeper MA Kramer KM Krishna A | 2008 | World J Surg2008，32，7： | 1 |
| 15 | Integrated microalgae culture with food processing waste for wastewater remediation and enhanced biomass productivity显示文摘Waste generation from food manufacturing facilities poses a serious hazard like environmental degradation, water pollution, and land pollution due to its high nutrient composition. Specifically, solid waste(powder) disposal requires additional energy sources in terms of scientific treatment, structured collection, and disposal packaging according to the safety regulation. Thus, this research discusses the viewpoint of integrating food processing waste as an organic carbon source with BG-11 medium for Chlorella vulgaris(FSP-E) growth. The food processing waste powders investigated in this study were obtained from milk, and biscuit manufacturing facilities. The culture medium was modified by combining both BG-11 and food processing waste powders to identify the optimal algal growth and biochemical content.Compared to the microalgae grown in BG-11 alone(IBG), the combination of biscuit waste and IBG produced higher biomass concentration(44%), with increased lipid(11%), protein(20%), and carbohydrate(57%) contents. Chlorella vulgaris was able to uptake nutrients from the culture medium with combination of food processing waste and IBG thus enhancing its growth. The results obtained also indicate that an integrated culture system using food processing waste and synthetic sources can generate energy out of waste by improving the bio-composition of the microalgae biomass. | Angela Paul Peter Kit Wayne Chew Apurav Krishna Koyande Heli Siti Halimatul Munawaroh Amit Bhatnagar Yang Tao Chihe Sun Fubao Sun Zengling Ma Pau Loke Show | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员