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| 1 | Postoperative bile leakage managed successfully by intrahepatic biliary ablation with ethanol显示文摘我们报导手术后的倔强的胆汁漏的一个案例与乙醇由肝内的胆汁的脱离成功地设法。与肝细胞癌诊断的一个 75 岁的人包括有尾的脑叶和前面的片断的部分经历了扩大以后的 segmentectomy。纳入胆汁管的前面的分支的肝的肿瘤小心地被分开并且 resected。手术后地从肝表面排干的液体包含了全部的胆红素的高集中,在每天的 150 mL 的经常的体积。在 d 上 32 在外科以后,引流管的 fistulogram 表明了前面的胆汁管的改进。内视镜后退胆管造影术表明了近似前面的胆汁管和外部前面的胆汁管的没有改进的完全的阻塞。在 d 上 46 在外科以后,一后退 transhepatic 胆汁的排水(RTBD ) 试管在开的外科下面被插入到前面的胆汁管。然而,拿的 RTBD 的对比研究 7 瞬间外科以后表明尽管有延长保守管理,管仍然是专利,我们因此决定执行孤立的胆汁管的乙醇脱离。四 mL 纯乙醇被注入孤立的前面的胆汁管十分钟,过程一个星期正在被重复五次。追随者 23 尝试,胆汁果汁的体积每天到达了不到 10 mL。RTBD 二天以后被夹钳并且搬迁。在 RTBD 移动以后,病人没有抱怨或症状。没有肝脓肿形成,后续磁性的回声成像表明了注射乙醇的前面的片断的萎缩。 | Tetsuya Shimizu Hiroshi Yoshida Yasuhiro Mamada Nobuhiko Taniai Satoshi Matsumoto Yoshiaki Mizuguchi Shigeki Yokomuro Yasuo Arima Koho Akimaru Takashi Tajiri | 2006 | World Journal of Gastroenterology2006，12，21： | 9 |
| 2 | 面向大规模定制的家具模块编码与配置技术显示文摘针对面向大规模定制的家具模块编码与配置技术进行了探讨与分析,并以芬兰某企业的模块配置器为例,阐述其配置原理与流程,以期为国内家具企业实现从大规模生产向大规模定制的模式转换,提供路径指导与技术支持。 | 李兵 Seppo Torvinen 关惠元 Mikko Koho | 2012 | 木材工业2012，26，4： | 6 |
| 3 | Confocal-based fluorescence fluctuation spectroscopy with a SPAD array detector显示文摘The combination of confocal laser-scanning microscopy(CLSM)and fluorescence fluctuation spectroscopy(FFS)is a powerful tool in studying fast,sub-resolution biomolecular processes in living cells.A detector array can further enhance CLSM-based FFS techniques,as it allows the simultaneous acquisition of several samples-essentially images-of the CLSM detection volume.However,the detector arrays that have previously been proposed for this purpose require tedious data corrections and preclude the combination of FFS with single-photon techniques,such as fluorescence lifetime imaging.Here,we solve these limitations by integrating a novel singie-photon-avalanche-diode(SPAD)array detector in a CLSM system.We validate this new implementation on a series of FFS analyses:spot-variation fluorescence correlation spectroscopy,pair-correlation function analysis,and image-derived mean squared displacement analysis.We predict that the unique combination of spatial and temporal information provided by our detector will make the proposed architecture the method of choice for CLSM-based FFS. | Eli Slenders Marco Castello Mauro Buttafava Federica Villa Alberto Tosi Luca Lanzanó Sami Valtteri Koho Giuseppe Vicidomini | 2021 | Light(Science & Applications)2021，10，2： | 2 |
| 4 | Long-term results of elective hepatectomy for the treatment of ruptured hepatocellular carcinoma显示文摘 | Hiroshi Yoshida Yasuhiro Mamada Nobuhiko Taniai Yoshiaki Mizuguchi Daisuke Kakinuma Yoshinori Ishikawa Tomohiro Kanda Satoshi Matsumoto Koich Bando Koho Akimaru Takashi Tajiri | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，2： | 2 |
| 5 | Effect of transforming growth factor-β1 on human intrahepatic cholangiocarcinoma cell growth显示文摘AIM: To elucidate the biological effects of transforming growth factor-β1 (TGF-β1) on intrahepatic cholan- giocarcinoma (ICC). METHODS: We investigated the effects of TGF-β1 on human ICC cell lines (HuCCT1, MEC, and HuH-28) by monitoring the influence of TGF-β1 on tumor growth and interleukin-6 (IL-6) expression in ICC cells. RESULTS: All three human ICC cell lines produced TGF-β1 and demonstrated accelerated growth in the presence of TGF-β1 with no apoptotic effect. Studies on HuCCT1 revealed a TGF-β1-induced stimulation of the expression of TGF-β1, as well as a decrease in TGF-β1 mRNA expression induced by neutralizing anti-TGF-β1 antibody. These results indicate that TGF-β1 stimulates the production and function of TGF-β1 in an autocrine fashion. Further, IL-6 secretion was observed in all three cell lines and exhibited an inhibitory response to neutralizing anti-TGF-β1 antibody. Experiments using HuCCT1 revealed a TGF-β1-induced acceleration of IL-6 protein expression and mRNA levels. These findings demonstrate a functional interaction between TGF-β1 and IL-6. All three cell lines proliferated in the presence of IL-6. In contrast, TGF-β1 induced no growth effect in HuCCT1 in the presence of small interfering RNA against a specific cell surface receptor of IL-6 and signal transducer and activator of transcription-3. CONCLUSION: ICC cells produce TGF-β1 and confer a TGF-β1-induced growth effect in an autocrine fashion.TGF-β1 activates IL-6 production, and the functional interaction between TGF-β1 and IL-6 contributes to ICC cell growth by TGF-β1. | Tetsuya Shimizu Shigeki Yokomuro Yoshiaki Mizuguchi Yutaka Kawahigashi Yasuo Arima Nobuhiko Taniai Yasuhiro Mamada Hiroshi Yoshida Koho Akimaru Takashi Tajiri | 2006 | World Journal of Gastroenterology2006，12，39： | 2 |
| 6 | Reconstruction Of the vena cava with the peritoneum 显示文摘 | Koho A Onda M Tajiri T | 2000 | Am J Surg2000，179，： | 1 |
| 7 | Monoclonal antibodies to antigens associated with transitional cell carcinoma of the human urinary bladder显示文摘 | KOHO H PAULIE S BEN-AISSA H | 1984 | Cancer Immunol Immunother1984，17，3： | 1 |
| 8 | Effects of age and concentrate feeding on the expres-sion of MCT 1 and CD147 in the gastrointestinal tractof goats and Hereford finishing beef bulls 显示文摘 | KOHO N M TAPONEN J TIIHONEN H | 2011 | Re-search in Veterinary Science2011，90，2： | 1 |
| 9 | Sequence variations and two levels of MCT1 and CD147 expression in red blood cells and gluteus muscle of horses显示文摘 | Koho NM Mykkanen AK Reeben M | 2012 | Gene2012，491，1： | 1 |
| 10 | Self organization of a massive document collection显示文摘 | Koho nen T Kaski S Lagus K | 2000 | IEEE Transactions on Neural Networks2000，11，3： | 1 |
| 11 | Association of fear of movement and leisure-time physical activity among patients with chronic pain显示文摘 | KOHO P ORENIUS T KAUTIAINEN H | 2011 | Journal of Rehabilitation Medicine2011，43，9： | 1 |
| 12 | Repeated allergen exposure of sensitized Brown-Norway rats induces airway cell DNA synthesis and remodeling 显示文摘 | Salmon M Walsh DA Koho H | 1999 | Eur Respir J1999，14，： | 1 |
| 13 | CLINICAL AND SUBCLINICAL ACUTE REJECTION EARLY AFTER LIVER TRANSPLANTATION: CONTRIBUTING FACTORS AND RELEVANCE FOR THE LONG-TERM COURSE显示文摘 | Christa Tippner Bj?rn Nashan Ken Hoshino Elke Schmidt-Sandte Koho Akimaru Klaus H.W. B?ker Hans J. Schlitt | 2001 | Transplantation2001，，6： | 1 |
| 14 | Resection of Over 290 Polyps During Emergency Surgery for Four Intussusceptions with Peutz–Jeghers Syndrome: Report of a Case显示文摘 | Koho Akimaru Shuji Katoh Shingo Ishiguro Kenji Miyake Kimiyoshi Shimanuki Takashi Tajiri | 2006 | Surgery Today2006，，11： | 1 |
| 15 | From the cover:the transcriptional responses of respiratory epithelial cells to Bordetella Pertussis reveal host defensive and pathogen counter-defensive strategies显示文摘 | Belcher C E Drenkow J Kohoe B | 2000 | Natl Acad Sci USA2000，97，13： | 1 |
| 16 | Effects of ammonia plasma treatment on the surface characteristics of carbon fibers 显示文摘 | Wen Hua-Chiang Yang Koho Wu K L | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 17 | A comparison of immuno- genicity of norovirus GII-4 virus-like particles and P-particles 显示文摘 | Tannninen K I-/uhti L Koho T | 2012 | Immunology2012，135，1： | 1 |
| 18 | Effects of ammonia plasma treatment on the surface characteristics of carbon fibers显示文摘 | Hua-Chiang Wen Koho Yang | 2006 | Surface&Coatings Technology2006，200，： | 1 |
| 19 | Differential ozone sensitivity of rice cuhivars as indicated by visible injury and grain yield 显示文摘 | SAWADA H KOHO Y | 2009 | Plant Biology2009，11，1： | 1 |
| 20 | Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice显示文摘 | Koho T Koivunen MR Oikarinen S | 2014 | Antiviral Res2014，104，： | 1 |
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