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| 1 | Flexible and biocompatible high-performance solid-state micro-battery for implantable orthodontic system显示文摘To augment the quality of our life,fully compliant personalized advanced health-care electronic system is pivotal.One of the major requirements to implement such systems is a physically flexible high-performance biocompatible energy storage(battery).However,the status-quo options do not match all of these attributes simultaneously and we also lack in an effective integration strategy to integrate them in complex architecture such as orthodontic domain in human body.Here we show,a physically complaint lithium-ion micro-battery(236μg)with an unprecedented volumetric energy(the ratio of energy to device geometrical size)of 200 mWh/cm^(3) after 120 cycles of continuous operation.Our results of 90%viability test confirmed the battery’s biocompatibility.We also show seamless integration of the developed battery in an optoelectronic system embedded in a threedimensional printed smart dental brace.We foresee the resultant orthodontic system as a personalized advanced health-care application,which could serve in faster bone regeneration and enhanced enamel health-care protection and subsequently reducing the overall health-care cost. | Arwa T.Kutbee Rabab R.Bahabry Kholod O.Alamoudi Mohamed T.Ghoneim Marlon D.Cordero Amani S.Almuslem Abdurrahman Gumus Elhadj M.Diallo Joanna M.Nassar Aftab M.Hussain Niveen M.Khashab Muhammad M.Hussain | 2017 | npj Flexible Electronics2017，1，1： | 2 |
| 2 | Transforming growth factor-betal-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin ex-pression 显示文摘 | Hefts M Hubert P Kholod N | 2008 | Am J Pathol2008，，172： | 1 |
| 3 | Large current radiator with S-diode switch显示文摘 | Pochanin G P Kholod P V | 2001 | IEEE Trans on Electromag Compat2001，43，1： | 1 |
| 4 | Update in the methodology of the chronic stress paradigm:internal control matters显示文摘 | Strekalova T Couch Y Kholod N | 2011 | Behav Brain Funct2011，7，： | 1 |
| 5 | Update in the methodology of the chronic stress paradigm: internal control matters显示文摘 | Strekalova T Couch Y Kholod N | 2011 | Behav Brain Funct2011，，7： | 1 |
| 6 | Band structure of Mg2Si and Mg2Ge semiconducting compounds with a strained crystal lattice显示文摘 | A. V. Krivosheeva A. N. Kholod V. L. Shaposhnikov A. E. Krivosheev V. E. Borisenko | 2002 | Semiconductors2002，，5： | 1 |
| 7 | Mutant ubiquitin (UBB +1 ) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)显示文摘 | Frank J.A. Dennissen Natalia Kholod Denise J.H.P. Hermes Nadja Kemmerling Harry W.M. Steinbusch Nico P. Dantuma Fred W. van Leeuwen | 2011 | FEBS Letters2011，，16： | 1 |
| 8 | The mechanism of unimolecular decomposition of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane:A computational DFT study显示文摘 | OkovytyyS Kholod Y Qasim M etal | 2005 | The Journal of Physical Chemistry A2005，109，12： | 1 |
| 9 | Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix显示文摘 | Delvenne P Herman L Kholod N | 2007 | Mol Cell Endocrinol2007，264，12： | 1 |
| 10 | Optical properties and structure of amorphous silicon films prepared by CVD显示文摘 | ALEXANDER N KHOLOD STEFANO OSSICINI | 2003 | Surface Science2003，527，： | 1 |
| 11 | Update in the methodology of the chronic stress paradigm : internal control malters显示文摘 | Strekalova T Couch Y Kholod N | 2011 | Behavioral & Brain Functions2011，79，2： | 1 |
| 12 | Certain exact solutions in the theory of elastic plates 显示文摘 | Andrianov I V Kholod E G | 1986 | Journal of Applied Mechanics and Technical Physics1986，，： | 1 |
| 13 | Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix显示文摘 | Delvenne P Herman L Kholod N | 2007 | Mol Cell Endocrinol2007，264，12： | 1 |
| 14 | Update in the methodology of the chronic stress paradigm: internal control matters显示文摘 | Strekalova T Couch Y Kholod N | 2011 | Behav brain funct2011，7，： | 1 |
| 15 | Transforming growth factor- beta1 - mediated Slug and Snail transcription factor upregulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression 显示文摘 | Herfs M Hubert P Kholod N | 2008 | Am J Pathol2008，172，5： | 1 |
| 16 | Effect of Three Different Growth Media on Yield and Oil Constituents of Rosemary (Rosmarinus officinalis L.) under Protected Agriculture Conditions显示文摘 | Kholod F. Abou Seedo Ahmed A. Salih Ahmed A. Taha | 2014 | Journal of Agricultural Science and Technology(A)2014，4，5： | 0 |
| 17 | Identifying patient-specific flow of signal transduction perturbed by multiple single-nucleotide alterations显示文摘Background:Identifying patient-specific flow of signal transduction perturbed by multiple single-nucleotide alterations is critical for improving patient outcomes in cancer cases.However,accurate estimation of mutational effects at the pathway level for such patients remains an open problem.While probabilistic pathway topology methods are gaining interest among the scientific community,the overwhelming majority do not account for network perturbation effects from multiple single-nucleotide alterations.Methods:Here we present an improvement of the mutational forks formalism to infer the patient-specific flow of signal transduction based on multiple single-nucleotide alterations,including non-synonymous and synonymous mutations.The lung adenocarcinoma and skin cutaneous melanoma datasets from TCGA Pan-Cancer Atlas have been employed to show the utility of the proposed method.Results:We have comprehensively characterized six mutational forks.The number of mutated nodes ranged from one to four depending on the topological characteristics of a fork.Transitional confidences(TCs)have been computed for every possible combination of single-nucleotide alterations in the fork.The performed analysis demonstrated the capacity of the mutational forks formalism to follow a biologically explainable logic in the identification of high-likelihood signaling routes in lung adenocarcinoma and skin cutaneous melanoma patients.The findings have been largely supported by the evidence from the biomedical literature.Conclusion:We conclude that the formalism has a great chance to enable an assessment of patient-specific flow by leveraging information from multiple single-nucleotide alterations to adjust the transitional likelihoods that are solely based on the canonical view of a disease. | Olha Kholod Chi-Ren Shyu Jonathan Mitchem Jussuf Kaifi Dmitriy Shin | 2020 | Quantitative Biology2020，8，4： | 0 |
| 18 | Removal of Cu(II),Pb(II),Mg(II),and Fe(II) by Adsorption onto Alginate/Nanocellulose Beads as Bio-Sorbent显示文摘Alginate blended with cellulose nanocrystals(CNC),cellulose nanofibers(CNF),and tri-carboxylate cellulose nanofibers(TPC-CNF)prepared and encapsulated in the form of microcapsules(bio-polymeric beads).The cellulosic nanomaterials that used in this study were investigated as nanomaterials for wastewater treatment applications.Batch experiments were performed to study the removal of copper,lead,magnesium,and iron from aqueous solutions by the prepared beads.The effects of the sorbent dosage and the modified polymers on the removing efficiency of the metal cations were examined.Atomic absorption was used to measure the metal ions concentrations.The modified bio-polymeric beads(Alg-CNF,Alg-CNC,and Alg-TPC-CNF)exhibited high-efficiency towards removing of the metal cations;Cu^(2+),Pb^(2+),Mg^(2+),and Fe^(2+).The Alg-TPC-CNF composite was exhibited excellent removing efficiency which around 95%for Pb,92%for Cu,43%for Fe and 54%for Mg.These outcomes affirm that the utilization of nanomaterials giving higher adsorption capacities contrasted with similar material in its micro or macrostructure form. | Ragab E.Abou-Zeid Korany A.Ali Ramadan M.A.Gawad Kholod H.Kamal Samir Kamel Ramzi Khiari | 2021 | Journal of Renewable Materials2021，9，4： | 0 |
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