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| 1 | Management of borderline and locally advanced pancreatic cancer:Where do we stand?显示文摘Many patients with pancreas cancer present with locally advanced pancreatic cancer(LAPC).The principle tools used for diagnosis and staging of LAPC include endoscopic ultrasound,axial imaging with computed tomography and magnetic resonance imaging,and diagnostic laparoscopy.The definition of resectability has historically been vague,as there is considerable debate and controversy as to the definition of LAPC.For the patient with LAPC,there is some level of involvement of the surrounding vascular structures,which include the superior mesenteric artery,celiac axis,hepatic artery,superior mesenteric vein,or portal vein.When feasible,most surgeons would recommend possible surgical resection for patients with borderline LAPC,with the goal of an R0 resection.For initially unresectable LAPC,neoadjuvant should be strongly considered.Specifically,these patients should be offered neoadjuvant therapy,and the tumor should be assessed for possible response and eventual resection.The efficacy of neoadjuvant therapy with this approach as a bridge to potential curative resection is broad,ranging from 3%-79%.The different modalities of neoadjuvant therapy include sin-gle or multi-agent chemotherapy combined with radiation,chemotherapy alone,and chemotherapy followed by chemotherapy with radiation.This review focuses on patients with LAPC and addresses recent advances and controversies in the field. | Jin He Andrew J Page Matthew Weiss Christopher L Wolfgang Joseph M Herman Timothy M Pawlik | 2014 | World Journal of Gastroenterology2014，20，9： | 11 |
| 2 | Pathological effects of orally administered estradiol to rainbow trout 显示文摘 | Herman R L Kincaid H L | 1988 | Aquaculture1988，72，12： | 2 |
| 3 | Isolation and Characterization of Two Bacteriocins Produced by Enterococcusfaecium Strains Inhibitory to Listeria monocytogenes 显示文摘 | Vlaemynck G Herman L Coudijzer K | 1994 | Int J Food Microbiol1994，24，12： | 1 |
| 4 | Inactivation of the CDKN2/ p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers显示文摘 | Herman JG Merlo A Mao L | 1995 | Cancer Res1995，55，20： | 1 |
| 5 | R N A expression of breast cancer resistance protein, lung resistance-related protein, muhidrug resistance-associated protein 1 and 2, and muhidrug resistance gene 1 in breast cancer: correlation with chemo-therapeutic re sponse 显示文摘 | Herman B John A F Max ime P L | 2003 | Clin Cancer Res2003，2，9： | 1 |
| 6 | Heavy gas dispersion models显示文摘 | Blackmore D R Herman M N Woodward J L | 1982 | Journal of Hazardous Materials1982，，6： | 1 |
| 7 | Two--week &dministration of the combined serotonin--nor&dren&line reupt&ke inhibitor duloxetine&ugments functioning of mesolimbic incentive processing circuits显示文摘 | Ossew&&rde L Verke$ FJ Hermans EJ et aI | | Biol Psychiatry0，70，6： | 1 |
| 8 | Spiral CT of the temporal bone:value of image reconstruction at submillimetric table increments显示文摘 | Hermans R Marchal G Feenstra L | 1995 | Neuroradiology1995，37，： | 1 |
| 9 | A three-component dicamba O-demethylase from Pseudomonas maltophilia, Strain DI- 6 : gene isolation, characterization, and heterologous expression 显示文摘 | Herman P L Behrens M Chakraborty S | 2005 | J Biol Chem2005，280，24： | 1 |
| 10 | β subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell line 显示文摘 | Herman M Bernardo R Rodolfo L | 1997 | Proc Natl Acad Sci USA1997，94，14： | 1 |
| 11 | Multiple sclerosis and age at infectionwithcommon virus显示文摘 | Herman MA Zhang SM Lipworth L | 2001 | Epidemiology2001，12，3： | 1 |
| 12 | Flow cytometric evaluation of a model for phagocytosis of cells undergoing apoptosis显示文摘 | Schrijvers DM Martinet W De Meyer GR Andries L Herman AG Kockx MM | 2004 | J Immunol Methods2004，287，12： | 1 |
| 13 | Modal testing and analysis of structures under operational conditions显示文摘 | Hermans L Vender H | 1999 | Mechanical Systems and Signal Processing1999，13，2： | 1 |
| 14 | Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes 显示文摘 | Qian T Nieminen A L Herman B | 1997 | Ame J Physio1997，273，： | 1 |
| 15 | Sealing Pond bottoms with muddy water显示文摘 | Herman B Jamie L Robert C R | 2001 | Ecological Engineering2001，18，2： | 1 |
| 16 | Characterization of poly(vinyl alcohol)/poly (ethylene glycol)hydrogels and PVA-derived hybrids by small-angle X-ray scattering and FTIR spectroscopy显示文摘 | Herman S Rodrigo L Alexandra A | 2004 | Polymer2004，45，： | 1 |
| 17 | Structural model identification from real operating conditions显示文摘 | Van der Auweraer H Hermans L | 1999 | S V Sound and Vibration1999，33，： | 1 |
| 18 | Fla-DGGE analysis of Campylobacter jejuni and Campylobacter coli in cecal samples of broilers without cultivation 显示文摘 | Najdenski H Heyndrickx M Herman L | 2008 | Veterinary Microbiology2008，127，1： | 1 |
| 19 | Chipping perfor-mance of three processing potato cultivars during long termstorage at two temperature regimes显示文摘 | Herman T J Love S L Shaif B | 1996 | American PotatoJournal1996，，73： | 1 |
| 20 | Implications ofincreased tissue transglutaminase (TG2) expression indrug-resistant breast cancer (MCF-7) cells显示文摘 | HERMAN J F MANDALA L S MEHTA K | 2006 | Oncogene2006，25，21： | 1 |
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