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| 1 | Qinghu zircon:A working reference for microbeam analysis of U-Pb age and Hf and O isotopes显示文摘Zircon is the most useful mineral for studies in U-Pb geochronology and Hf and O isotope geochemistry.Matrix effect is a major problem of the microbeam techniques such as SIMS and LA-(MC)-ICPMS.Therefore,external standardization using well-characterized natural zircon standards is fundamental for accurate microbeam measurements.While the isotopic geochronology and geochemistry laboratories equipped with microbeam analytical facilities have been increasingly established in China during the past decade,applications of the isotopic microanalysis are still limited due to shortage of available standards.We report here the Qinghu zircon as a potential new working reference for microbeam analysis of zircon U-Pb age and O-Hf isotopes.This zircon was separated from the Qinghu quartz monzonite from the western Nanling Range,Southeast China.It is fairly homogeneous in U-Pb age and Hf and O isotopes in terms of large amounts of mircobeam measurements by LA-MC-ICPMS and SIMS at the scales of 20–60 m.SIMS measurements yield consistent206Pb/238U age within analytical uncertainties with that obtained by ID-TIMS.Precise determinations of O isotopes by IRMS and Hf isotopes by solution MC-ICPMS are in good agreement with the statistical mean of microbeam measurements.We recommend U-Pb age of=159.5±0.2 Ma(2SE),18O=5.4‰±0.2‰(2SD)and176Hf/177Hf=0.283002±0.000004(2SD)as the best reference values for the Qinghu zircon. | LI XianHua TANG GuoQiang GONG Bing YANG YueHeng HOU KeJun HU ZhaoChu LI QiuLi LIU Yu LI WuXian | 2013 | Chinese Science Bulletin2013，58，36： | 60 |
| 2 | Prognostic factors of refractory NSCLC patients receiving anlotinib hydrochloride as the third-or further-line treatment显示文摘Objective:Anlotinib hydrochloride is a multitarget tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor,fibroblast growth factor receptor,platelet-derived growth factor receptor,c-Kit,and c-MET;therefore,it exhibits both antitumor and anti-angiogenetic activities.A phase III trial has shown that anlotinib improved progression-free survival(PFS)and overall survival(OS)in patients with advanced non-small cell lung cancer(NSCLC),who presented with progressive disease or intolerance after standard chemotherapy.This study aimed to analyze the characteristics of patients receiving anlotinib treatment to determine the dominant populations who are fit for the treatment.Methods:Data were collected from March 2015 to January 2017 from a randomized,double-blind,placebo-controlled,multicenter,phase III trial of anlotinib(ALTER0303).A total of 437 patients were enrolled and randomly allocated(2:1)to the anlotinib and placebo groups.Kaplan–Meier analysis and log-rank test were performed to compare PFS and OS.Cox proportional hazards model was adopted for multivariate prognostic analysis.Results:Multivariate analysis indicated that high post-therapeutic peripheral blood granulocyte/lymphocyte ratio and elevated alkaline phosphatase levels were independent risk factors for PFS.Meanwhile,elevated thyroid-stimulating hormone,blood glucose,and triglyceride levels;hypertension;and hand–foot syndrome were independent protective factors of PFS.High posttherapeutic peripheral blood granulocyte/lymphocyte ratio,an Eastern Cooperative Oncology Group(ECOG)score≥2,and the sum of the maximal target lesion length at baseline were independent risk factors of OS,and hypertriglyceridemia was an independent protective factor of OS.Conclusions:This study preliminarily explored the possible factors that affected PFS and OS after anlotinib treatment in patients with advanced refractory NSCLC,and the baseline characteristics of the therapeutically dominant populations were then identified. | Jing Wang Yizhuo Zhao Qiming Wang Li Zhang Jianhua Shi Zhehai Wang Ying Cheng Jianxing He Yuankai Shi Hao Yu Yang Zhao Weiqiang Chen Yi Luo Xiuwen Wang Kejun Nan Faguang Jin Jian Dong Baolan Li Zhujun Liu Baohui Han Kai Li | 2018 | Cancer Biology & Medicine2018，15，4： | 46 |
| 3 | Quasi-equilibrium glide adaptive guidance for hypersonic vehicles显示文摘The entry-glide guidance strategy for hypersonic vehicles that can satisfy both terminal and path constraints is investigated in this paper.We propose a quasi-equilibrium glide adaptive guidance methodology based on the quasi-equilibrium glide condition(QEGC),which innovatively utilizes the quasi-equilibrium glide phenomenon in lifting entry.With the aid of QEGC,both range and terminal velocity can be predicted analytically with high precision.The path constraints are converted into angle of attack constraints,which has been difficult to realize by using traditional predictive guidance methods.The algorithm is independent of the standard trajectory.All the guidance commands,including the bank angle and the angle of attack,are calculated analytically in real time,which endows the algorithm with sufficient adapbility.The results of a CAV-H vehicle guidance test show that the algorithm leads the vehicle along a quasi-equilibrium glide trajectory satisfying both the terminal and path constraints and has sufficient flexibility for occasional mission changes.Furthermore,the robustness of the guidance algorithm under disturbances is validated through a Monte Carlo simulation. | XU MingLiang CHEN KeJun LIU LuHua TANG GuoJian | 2012 | Science China(Technological Sciences)2012，55，3： | 30 |
| 4 | Different Effects of Homocysteine and Oxidized Low Density Lipoprotein on Methylation Status in the Promoter Region of the Estrogen Receptor α Gene显示文摘我们调查了人的效果半胱氨酸(Hcy ) 和在雌激素受体高山的倡导者区域的 DNA methylation 上的氧化低密度脂蛋白(ox-LDL ) 哈(ERalpha ) 基因,和它在动脉粥样硬化的致病的潜在的机制。人的有教养的光滑的肌肉房间(SMC ) 被 Hcy 和 ox-LDL 为时间的不同经期与不同集中对待。DNA methylation 地位是由嵌套的 methylation 特定的聚合酶链反应的 assayed,在 SMC 和泡沫房间形成积累了的类脂化合物被检验,油红 O 染色。SMC 的增长是由 the3-(4,5-dimethylthiazol-2-yl ) 的 assayed -2,5-diphenyltetrazolium 溴化物方法。结果证明 ox-LDLin 节制导致的集中(10-40 mg/L ) 在 SMCs.However 的 ERagene 的倡导者区域的 de novo methylation, ox-LDL 的高集中(50 mg/L ) ,导致了时代的 demethylation。 Hcytreatment 与 aconcentration 在时代基因的倡导者区域导致了 de novo methylation --并且对待时间依赖者举止,并且在 SMCproliferation.These 数据上支持效果的一个剂量依赖者显示为动脉粥样硬化的二个风险因素有在 SMCs.However 的时代基因的倡导者区域导致 de novo methylation 的功能, ox-LDL 的高集中( 50 mg/L )导致了 demethylation ,显示有不同力量力量的动脉粥样硬化的不同风险因素在时代基因的倡导者区域引起不同异常 methylation 模式。Hcy 的 atherogenic 机制可能包含 hypermethylationof 时代基因,在动脉粥样硬化患者损害导致 SMC 的增长。 | Yushan HUANG~1 Kejun PENG~2 Juan SU~1 Yuping HUANG~3 Yizhon XU~1 and Shuren WANG~1 ~1Department of Pathophysiology,West China School of Preclinic Medical Sciences & Forensic Medicine,Sichuan University,Chengdu 610041.China ~2Department of Laboratory Medicine,Chengdu Medical College,Chengdu 610500,China ~3Department of Biochemistry and Molecular Bilogy,Gannan Medical College,Ganzhou 341000,China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，1： | 25 |
| 5 | Episodic crustal anatexis and the formation of Paiku composite leucogranitic pluton in the Malashan Gneiss Dome, Southern Tibet显示文摘The Paiku composite leucogranitic pluton in the Malashan gneiss dome within the Tethyan Himalaya consists of tourmaline leucogranite,two-mica granite and garnet-bearing leucogranite.Zircon U-Pb dating yields that(1)tourmaline leucogranite formed at28.2±0.5 Ma and its source rock experienced simultaneous metamorphism and anatexis at 33.6±0.6 Ma;(2)two-mica granite formed at 19.8±0.5 Ma;(3)both types of leucogranite contain inherited zircon grains with an age peak at^480 Ma.These leucogranites show distinct geochemistry in major and trace elements as well as in Sr-Nd-Hf isotope compositions.As compared to the two-mica granites,the tourmaline ones have higher initial Sr and zircon Hf isotope compositions,indicating that they were derived from different source rocks combined with different melting reactions.Combined with available literature data,it is suggested that anatexis at^35 Ma along the Himalayan orogenic belt might have triggered the initial movement of the Southern Tibetan Detachment System(STDS),and led to the tectonic transition from compressive shortening to extension.Such a tectonic transition could be a dominant factor that initiates large scale decompressional melting of fertile high-grade metapelites along the Himalayan orogenic belt.Crustal anatexis at^28 Ma and^20 Ma represent large-scale melting reactions associated with the movement of the STDS. | GAO LiE ZENG LingSen HOU KeJun GUO ChunLi TANG SuoHan XIE KeJia HU GuYue WANG Li | 2013 | Chinese Science Bulletin2013，58，28： | 23 |
| 6 | Ca. 2.5 Ga TTG rocks in the western Alxa Block and their implications显示文摘The Alxa Block is considered part of the North China Craton, but the unambiguous Archean basement has not been reported. In this study, we present the first evidence of the Neoarchean rocks in the Beidashan area of the western Alxa Block. The petrographic and geochemical data show that these rocks are granodiorite with TTG (tonalite-trondhjemite-granodiorite) characteristics. Zircon U-Pb dating gave an age of 2522±30 Ma for the magmatic core and 2496±11 Ma for the metamorphic recrystallized rim. The near-identical age between the Latest Neoarchean magmatism and the high-grade metamorphism shows that these features were related to the same Latest Neoarchean-Earliest Paleoproterozoic tectonothermal event. The age-corrected Hf (t) value is mainly between 0.4 and 4.9. The two-stage zircon Hf model age ranges from 2.7 to 3.0 Ga, suggesting that the Mesoarchean- Neoarchean (2.7-3.0 Ga) juvenile crust was reworked at the end of the Neoarchean in the western Alxa Block. These data suggest that the western Alxa Block experienced a Mesoarchean-Neoarchean crust growth and Latest Neoarchean-Earliest Paleoproterozoic tectonothermal event similar to the North China Craton. | GONG JiangHua ZHANG JianXin YU ShengYao LI HuaiKun HOU KeJun | 2012 | Chinese Science Bulletin2012，57，31： | 21 |
| 7 | Vision,application scenarios,and key technology trends for 6G mobile communications显示文摘With the global commercialization of the fifth-generation(5G)network,many countries,including China,USA,European countries,Japan,and Korea,have started exploring 6G mobile communication network,following the tradition of“planning the next while commercializing one generation”.Currently,studies on 6G networks are at the infancy stage.Research on the vision and requirements for 6G is still ongoing,and the industry is yet to clarify the key enabling technologies for 6G.However,6G will certainly build on the success of 5G.Therefore,developing high-quality 5G networks and seamlessly integrating 5G with verticals are the priorities before 2030,when 6G is projected to be commercialized.Also,global 5G standards will keep evolving to better support vertical applications.As a milestone,the Third-Generation Partnership Project(3GPP)published Release 16 in July 2020,which continuously enhanced the capabilities of mobile broadband service based on Release 15 and realized the support for low-delay and high-reliability applications,such as Internet of Vehicles and industrial Internet.Currently,3GPP is working on Releases 17 and 18,focusing on meeting the demands of medium-and high-data-rate machine communication with low-cost and high-precision positioning,which will be published in June 2022.Thus,6G networks will further expand the application fields and scope of the Internet of Things to accommodate those services and applications that are beyond the capabilities of 5G networks.Herein,we present our vision,application scenarios,and key technological trends for 6G networks.Furthermore,we propose several future research opportunities in 6G networks with regard to industrialization and standardization. | Zhiqin WANG Ying DU Kejun WEI Kaifeng HAN Xiaoyan XU Guiming WEI Wen TONG Peiying ZHU Jianglei MA Jun WANG Guangjian WANG Xueqiang YAN Jiying XIANG He HUANG Ruyue LI Xinhui WANG Yingmin WANG Shaohui SUN Shiqiang SUO Qiubin GAO Xin SU | 2022 | Science China(Information Sciences)2022，65，5： | 17 |
| 8 | In situ boron isotope measurements of natural geological materials by LA-MC-ICP-MS显示文摘There are two main methods to determine boron isotopic composition.One is the solution method,in which boron is purified after the samples are dissolved in solution and the boron isotope ratios are determined by thermal ionization mass spectrometry(P-TIMS and N-TIMS) or multicollector inductively coupled plasma mass spectrometry(MC-ICP-MS).The other is an in-situ analysis method,in which the in-situ boron isotopic ratios in minerals are analyzed directly using secondary ion mass spectrometry(SIMS) or laser ablation multicollector inductively coupled plasma mass spectrometry(LA-MC-ICP-MS).In the in-situ analysis method for boron isotopes,the multifarious chemical purification and separation processes of the solution method are avoided,with increased work efficiency.In addition,the microzones and microbeddings of minerals can be analyzed in-situ to reveal the fine processes and conditions of mineral formation.In this study,using the standard-sample-bracketing(SSB) method,mass bias of the instrument and the fractionation of isotopes were calibrated,and the in-situ determination method of LA-MC-ICP-MS for boron isotopes was established.Through detailed analyses on a series of boron isotope standards and samples,a matrix effect was assessed but not detected,and the analysis results were in accordance with the formerly reported values or P-TIMS determined values,within the error range.The analytical results for IAEA B4 and IMR RB1 with relatively high boron contents were δ 11B =-(8.36±0.58)‰(2σ,n=50) and δ 11B =-(12.96±0.97)‰(2σ,n=57),respectively;the analytical result for IAEA B6 with rela-tively low boron content was δ 11B =-(3.29±1.12)‰(2σ,n=35).In-situ measurements for B isotopes were performed on geo-logical samples such as tourmaline,ulexite,ludwigite,inyoite and ascharite,with the results consistent with those determined by P-TIMS,within the error range. | HOU KeJun LI YanHe XIAO YingKai LIU Feng TIAN YouRong | 2010 | Chinese Science Bulletin2010，55，29： | 13 |
| 9 | Optimal proportion of wind and PV capacity in provincial power systems based on bilevel optimization algorithm under low-carbon economy显示文摘In order to boost contributions of power systems to a low-carbon economy,the installed capacity of renewable power generation,such as wind and photovoltaic(PV)power generation should be well planned.A bilevel formulation is presented to optimize the proportion of wind and PV capacity in provincial power systems,in which,carbon emissions of generator units and features of renewable resources are taken into account.In the lowerlevel formulation,a time-sequence production simulation(TSPS)model that is suitable for actual power system has been adopted.In order to maximize benefits of energy conservation and emissions reduction resulting from renewable power generation,the commercial software called General Algebraic Modeling System(GAMS)is employed to optimize the annual operation of the power system.In the upper-level formulation,the optimal pattern search(OPS)algorithm is utilized to optimize the proportion of wind and PV capacity.The objective of the upper-level formulation is to maximize benefits of energy conservation and carbon emissions reductions optimized in the lowerlevel problem.Simulation results in practical provincial power systems validate the proposed model and corresponding solving algorithms.The optimization results can provide support to policy makers to make the polices related to renewable energy. | Yue YUAN Yang CAO Xinsong ZHANG Chun LIU Yuehui HUANG Peng LI Kejun QIAN | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，1： | 11 |
| 10 | Predicting intrinsic disorder in proteins: an overview显示文摘 | Bo He Kejun Wang Yunlong Liu Bin Xue Vladimir N Uversky A Keith Dunker | 2009 | Cell Research2009，19，8： | 11 |
| 11 | Late Mesozoic Ore-forming Events in the Ningwu Ore District, Middle-Lower Yangtze River Polymetallic Ore Belt, East China: Evidence from Zircon U-Pb Geochronology and Hf Isotopic Compositions of the Granodioritic Stocks显示文摘Late Mesozoic volcanic-subvolcanic rocks and related iron deposits, known as porphyry iron deposits in China, are widespread in the Ningwu ore district (Cretaceous basin) of the middle-lower Yangtze River polymetallic ore belt, East China. Two types of Late Mesozoic magmatic rocks are exposed: one is dioritic rocks closely related to iron mineralization as the hosted rock, and the other one is granodioritic (-granitic) rocks that cut the ore bodies. To understand the age of the iron mineralization and the ore-forming event, detailed zircon U-Pb dating and Hf isotope measurement were performed on granodioritic stocks in the Washan, Gaocun-Nanshan, Dongshan and Heshangqiao iron deposits in the basin. Four emplacement and crystallization (typically for zircons) ages of granodioritic rocks were measured as 126.1±0.5 Ma, 126.8±0.5 Ma, 127.3±0.5 Ma and 126.3±0.4 Ma, respectively in these four deposits, with the LA-MC-ICP-MS zircon U-Pb method. Based on the above results combined with previous dating, it is inferred that the iron deposits in the Ningwu Cretaceous basin occurred in a very short period of 131-127 Ma. In situ zircon Hf compositions of εHf(t) of the granodiorite are mainly from -3 to -8 and their corresponding 176Hf/177Hf ratio are from 0.28245 to 0.28265, indicating similar characteristics of dioritic rocks in the basin. We infer that granodioritic rocks occurring in the Ningwu ore district have an original relationship with dioritic rocks. These new results provide significant evidence for further study of this ore district so as to understand the ore-forming event in the study area. | DUAN Chao LI Yanhe HOU Kejun YUAN Shunda LIU Jialin ZHANG Cheng | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 11 |
| 12 | Study on bed load transport for uniform sediment in laminar flow显示文摘Previous studies focused on the bed load transport rate for the condition of turbulent flow,while the knowledge of sediment transport in laminar flow is very limited.As an extreme case to reflect the viscous effect on sediment transport,sediment transport in laminar flow is considered in this paper.There are at least two factors affecting the transport rate of sediment under laminar flow conditions: (1) fluid forces;(2) particle to particle interactions.Together,these two factors represent the physical transport system.First,an exposure degree Probability Density Function (PDF) is developed to explore how the transport rate can be associated with characteristics of laminar flow and this factor reflects the particle to particle interactions,and the pickup probability equation in the absence of turbulence is developed based on the stochastic approach which reflects the exposure degree influence.Then,the formulas to calculate the critical shear stress of incipient motion and the bed load transport rate of fine uniform sediment are established.The derivation is made mainly based on Einstein’s bed load theory;we choose Einstein’s equation to model this system because we believe that the probabilistic approach taken is an appropriate way to account for the spatial and temporal variations in the forces causing sediment transport.These formulas have been tested against a wide range of existing laboratory data and compared with other existing empirical or semiempirical methods.The predictions by these newly proposed formulas are very good. | YANG FengGuang,LIU XingNian,CAO ShuYou,YANG KeJun & HUANG Er State Key Laboratory of Hydraulics and Mountain River Engineering,Sichuan University,Chengdu 610065,China | 2010 | Science China(Technological Sciences)2010，53，9： | 9 |
| 13 | Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging显示文摘Fractional anisotropy values in diffusion tensor imaging can quantitatively reflect the consistency of nerve fibers after brain damage, where higher values generally indicate less damage to nerve fibers. Therefore, we hypothesized that diffusion tensor imaging could be used to evaluate the effect of mild hypothermia on diffuse axonal injury. A total of 102 patients with diffuse axonal injury were randomly divided into two groups: normothermic and mild hypothermic treatment groups. Patient's modified Rankin scale scores 2 months after mild hypothermia were significantly lower than those for the normothermia group. The difference in average fractional anisotropy value for each region of interest before and after mild hypothermia was 1.32–1.36 times higher than the value in the normothermia group. Quantitative assessment of diffusion tensor imaging indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury. | Guojie Jing Xiaoteng Yao Yiyi Li Yituan Xie Wang’an Li Kejun Liu Yingchao Jing Baisheng Li Yifan Lv Baoxin Ma | 2014 | Neural Regeneration Research2014，9，2： | 9 |
| 14 | Flow resistance and its prediction methods in compound channels显示文摘一系列实验在由一条不平的主要隧道和不平的泛滥平原组成调查抵抗特征的一条大对称的复合隧道被执行在银行并且在银行流动上。有效曼宁, Darcy Weisbach, Chezy 系数和相对 Nikuradse 粗糙高度被分析。为预言合成粗糙系统地被总结的许多不同代表性的方法。除测量数据以外,为复合隧道的实验室数据和领域数据的一个广阔数字被收集并且过去常为不同分部部门检查这些方法的有效性包括垂直,水平,对角线和双性人部分部门。计算证明这些方法在在复合隧道估计合成粗糙导致了大错误,并且原因详细被分析。错误大小与分部部门有关。 | Kejun Yang Shuyou Cao Xingnian Liu | 2007 | Acta Mechanica Sinica2007，23，1： | 9 |
| 15 | Separation and Precise Measurement of Lithium Isotopes in Three Reference Materials Using Multi Collector-Inductively Coupled Plasma Mass Spectrometry显示文摘Lithium separation technique for three reference materials has been established together with precise determination of lithium isotope using a Neptune multi collector-inductively coupled plasma mass spectrometry (MC-ICP-MS). The solutions of lithium element standard reference materials, potassium, calcium, sodium, magnesium and iron single element, were used to evaluate analytical methods applied. Three separate stages of ion-exchange chromatography were carried out using organic cation-exchange resin (AG 50W-X8). Lithium was enriched for the three stages using different eluants, which are 2.8 M HCl, 0.15 M HCl and 0.5 M HCl in 30% ethanol, respectively. The columns for the first and second stages are made of polypropylene, and those for the third stage are made of quartz. Total reagent volume for the entire chemical process was 35 mL for three reference materials. The recovery yielded for the three stages is 98.9-101.2% with an average of 100.0%, 97.6- 101.9% with an average of 99.9%, and 99.8-103.3% with an average of 100.6%, respectively. The precision of this technique is conservatively estimated to be ±0.72-1.04‰ (2σ population), which is similar to the precision obtained by different authors in different laboratories with MC-ICP-MS. The δ 7 Li values ( 7 Li/ 6 Li relative to the IRMM-016 standard) determined for andesite (AGV-2) and basalt (BHVO-2) are 5.68‰ (n=18), 4.33‰ (n=18), respectively. The δ 7 Li value ( 7 Li/ 6 Li relative to the L-SVEC standard) determined for IRMM-016 is -0.01‰ (n=15). All these analytical results are in good agreement with those previously reported. In addition, the results for the same kinds of samples analyzed at the MLR Key Laboratory of Metallogeny and Mineral Assessment, Institute of Mineral Resources, Chinese Academy of Geological Sciences, are consistent with those obtained at the Plasma Laboratory, University of Maryland, within analytical uncertainty. According to these experiment results, it is concluded that this proposed procedure is a suitable method for determining the lithium isotopic composition of natural samples. | TIAN Shihong HOU Zengqian SU Aina HOU Kejun HU Wenjie LI Zhenzhen ZHAO Yue GAO Yanguang LI Yanhe YANG Dan YANG Zhusen | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 9 |
| 16 | Review of small aspheric glass lens molding technologies显示文摘 | Shaohui YIN Hongpeng JIA Guanhua ZHANG Fengjun CHEN Kejun ZHU | 2017 | Frontiers of Mechanical Engineering2017，12，1： | 9 |
| 17 | Provenance of the Paleoproterozoic Hutuo Group basal conglomerates and Neoarchean crustal growth in the Wutai Mountains,North China Craton:Evidence from granite and quartzite pebble zircon U-Pb ages and Hf isotopes显示文摘Zircon U-Pb ages(SHRIMP and LA-ICPMS) and Lu-Hf isotope data(LA-ICPMS) are presented for two granite and two quartzite pebbles from the basal conglomerates of the Sijizhuang Formation in the Hutuo Group from the Wutai Mountains area in the North China Craton.These two granite pebbles give zircon 207 Pb/206 Pb ages of 2513±8 Ma and 2527±8 Ma respectively,which are consistent with the emplacement ages of the Wangjiahui grey granite and Guangmingsi or Shifo granite in the Wutai Mountains.Detrital zircons from those two quartzite pebbles are mostly 2550-2490 Ma old with lesser number of 2800-2550 Ma grains,which is similar to the ages of detrital zircons from quartzites in the Gaofan Subgroup of the Neoarchean Wutai Group.Thus,the pebbles in the Hutuo Group basal conglomerates were derived locally from Wutai Mountains Neoarchean sources.Zircons from the Sijizhuang Formation conglomerate granite and quartzite pebbles mostly have positive ε Hf(t) values,a minority with ε Hf(t) values like model depleted mantle(DM) of the same age,but with most showing DM model ages 200-100 Ma.This indicates that most of the source materials were derived from the mantle within the previous 200 million years,whereas some are derived from 2550-2510 Ma juvenile crustal additions.This additional evidence suggests that in the North China Craton there was important initial polycyclic crustal formation and cratonization in the late Neoarchaean,prior to superimposed Palaeoproterozoic orogenic cycles. | DU LiLin YANG ChongHui WANG Wei REN LiuDong WAN YuSheng SONG HuiXia GAO LinZhi GENG YuanSheng HOU KeJun | 2012 | Science China Earth Sciences2012，55，11： | 8 |
| 18 | Analysis of DNA methylation variation in wheat genetic background after alien chromatin introduction based on methylation-sensitive amplification polymorphism显示文摘During the process of alien germplasm introduced into wheat genome by chromosome engineering, extensive genetic variations of genome structure and gene expression in recipient could be induced. In this study, we performed GISH (genome in situ hybridization) and AFLP (amplified fragment length po-lymorphism) on wheat-rye chromosome translocation lines and their parents to detect the identity in genomic structure of different translocation lines. The results showed that the genome primary struc-ture variations were not obviously detected in different translocation lines except the same 1RS chromosome translocation. Methylation sensitive amplification polymorphism (MSAP) analyses on genomic DNA showed that the ratios of fully-methylated sites were significantly increased in translo-cation lines (CN12, 20.15%; CN17, 20.91%; CN18, 22.42%), but the ratios of hemimethylated sites were significantly lowered (CN12, 21.41%; CN17, 23.43%; CN18, 22.42%), whereas 16.37% were fully-me-thylated and 25.44% were hemimethylated in case of their wheat parent. Twenty-nine classes of me-thylation patterns were identified in a comparative assay of cytosine methylation patterns between wheat-rye translocation lines and their wheat parent, including 13 hypermethylation patterns (33.74%), 9 demethylation patterns (22.76%) and 7 uncertain patterns (4.07%). In further sequence analysis, the alterations of methylation pattern affected both repetitive DNA sequences, such as retrotransposons and tandem repetitive sequences, and low-copy DNA. | ZHANG Yong LIU ZhaoHui LIU Cheng YANG ZuJun DENG KeJun PENG JinHua ZHOU JianPing LI GuangRong TANG ZongXiang REN ZhengLong | 2008 | Chinese Science Bulletin2008，53，1： | 8 |
| 19 | The design and performance analysis of optical wireless ACO-MC-CDMA system in the presence of clipping noise显示文摘Dear editor,With rapidly growing wireless data demand and the saturation of radio frequency(RF)spectrum,optical wireless communications(OWC)has become a viable candidate for indoor and medium range data transmission[1].In general,the perfor- | Peng DOU Guojie SONG Tong ZHAO Kejun JIA Li HAO | 2018 | Science China(Information Sciences)2018，61，2： | 8 |
| 20 | Formation and evolution mechanisms of large-clusters during rapid solidification process of liquid metal Al显示文摘A molecular dynamics simulation study has been performed for the formation and evolution characteristics of nano-clusters in a large-scale system consisting of 400000 atoms of liquid metal Al. The center-atom method combined with pair-bond analysis technique and cluster-type index method (CTIM) has been applied here to describe the structural configurations of various basic clusters. It is demonstrated that both the 1551 bond-type and the icosahedral cluster (12 0 12 0) constructed by 1551 bond-types are dominant among all the bond-types and cluster-types, respectively, in the system and play a critical role in the microstructure transitions of liquid metal Al. The nano-clusters (containing up to 150 atoms) are formed by the combination of some middle and small clusters with distinctly different sizes, through mutual competition by unceasing annex and evolution in a seesaw manner (in turn of obtaining and losing),which do not occur as the multi-shell structures accumulated with an atom as the center and the surrounding atoms are arranged according to a certain rule. This is the essential distinction of nano-cluster in liquid metal from those obtained by gaseous deposition, ionic spray methods, and so on. Though the nano-clusters differ from each other in shape and size, all of them possess protruding corners that could become the starting points of various dendrite structures in the solidification processes of liquid metals. | LIU Rangsu, DONG Kejun, LIU Fengxiang, ZHENG Caixing, LIU Hairong & LI Jiyong Department of Applied Physics, Hunan University, Changsha 410082, China College of Materials Science and Engineering, Hunan University, Changsha 410082, China College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China | 2005 | Science China(Physics,Mechanics & Astronomy)2005，48，1： | 7 |
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