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31篇 您的检索式:作者名="Kalueff"
    题名 作者 年代 出处 被引量
1糖尿病斑马鱼模型的建立与南极磷虾酶解物降血糖活性评价显示文摘采用联合20g/L葡萄糖溶液浸泡和10%胆固醇喂养20d快速建立了稳定的糖尿病斑马鱼模型,并用该模型对3 000~100Da南极磷虾酶解物(AKEH)的体内降血糖效果进行评价,具体考察AKEH对糖尿病斑马鱼DPP-IV的活性、理化指标(葡萄糖、甘油三酯、胆固醇)和与血糖水平相关基因(Insa、Glucagon、Pck1)表达水平的影响。结果表明:与阴性对照组相比,低剂量的3 000~100Da AKEH组分(1.35,2.70g/L)对糖尿病斑马鱼的理化指标与血糖相关基因表达水平影响不显著,而高剂量的3 000~100Da AKEH(5.40g/L)能降低其血糖的理化指标水平,显著抑制糖尿病斑马鱼DPP-IV活性与Glucagon基因和Pck1基因的表达水平、提高Insa基因表达水平。因此,3 000~100Da AKEH组分具有一定的降血糖功效。吉薇 章超桦 ALLAN V Kalueff 宋采 2019食品与机械2019,35,6:9
2What's wrong with my mouse model?Advances and strategies in animal modeling of anxiety and depression显示文摘KALUEFF A V WHEATON M MURPHY D L 2007Behav Brain Res2007,179,1:1
3Murphy DL Hypolocomotion,anxiety and serotonin syndrome-like behavior eontribute to the complex phenotype of serotonin transporter knock out mice显示文摘KALUEFF AV FOXMA GALLAGHER PS Genes Brain Behav0,6,8:1
4Role of GABA in memory and anxiety显示文摘Kalueff A Nutt D J 1996De- pression and anxiety1996,4,3:1
5The grooming analysis algorithm discriminates between different levels of anxiety in rats:potential utility for neurobehavioural stress research显示文摘Kalueff AV Tuohimaa P 2005J Neurosci Methods2005,143,2:1
6The vitamin D neuroendocrine system as a targetfor novel neurotropic drugs显示文摘Kalueff AV Minasyan A Keisala T Kuuslahti M Miettinen S Tuohimaa P 2006CNS Neurol Disord Drug Targets2006,5,3:1
7Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice 显示文摘Kalueff AV Fox MA Gallagher PS 2007Genes Brain Behav2007,6,4:1
8Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes显示文摘Kalueff AV Olivier JD Nonkes LJ 0,,:1
9Intranasal adminis- tration of human IL-6 increases the severity of chemically induced seizures in rats 显示文摘Kalueff A V Lehtimaki K A Ylinen A 2004Neurosci Lett2004,365,2:1
10The grooming analysis algorithm discriminates between different levels of anxiety in rats: potential utility for neurobe-havioural stress research显示文摘Kalueff A V Tuohimaa P 2005J Neurosci Methods2005,143,:1
11Intranasal ad- ministration of human IL-6 increases the severity of chemically in- duced seizures in rats显示文摘KALUEFF A V LEHTIMAKI K A YLINEN A 2004Neuroscience Letter2004,365,:1
12Intranasal administration of human IL-6 increases the severity of chemically induced seizures in rats显示文摘Kalueff AV Lehtimaki KA Ylinen A 2004Neurosci Lett2004,365,2:1
13Anxiety and otovestib-ular dis-orders:linking behavioral phenotypes in men and mice显示文摘Kalueff AV Ishikawa K Griffith AJ 0,,01:1
14Anxiety and otovestibular disorders:linking behavioral phenotypes in men and mice显示文摘KALUEFF A V ISHIKAWA K GRIFFITH A J 2008Behav Brain Res2008,186,:1
15Zebrafish as an emerging model for studying complex brain disorders显示文摘Allan V. Kalueff Adam Michael Stewart Robert Gerlai 2013Trends in Pharmacological Sciences2013,,:1
16Anxiety and otovestibular disorders= linking behavioral phenotypes in men and mice 显示文摘Kalueff AV Ishikawa K Griffith AJ 2008Behave Brain Res2008,186,:1
17Role of GABA in anxiety and depression 显示文摘Kalueff AV Nutt DJ 2007Depress Anxiety2007,24,7:1
18Role of GABA in anxiety and depression显示文摘Kalueff A V Nutt D J 2007Depression and Anxiety2007,24,7:1
19Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes显示文摘Kalueff AV Olivier JD Noakes LJ 2010Neurosci Biobehav Rev2010,34,3:1
20Role of GABA in anxiety and depression显示文摘Kalueff A V Nutt D J 0,,07:1
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