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| 1 | Polysomnographic assessment of respiratory disturbance during deep propofol sedation for endoscopic submucosal dissection of gastric tumors显示文摘AIM To investigate that polysomnographic monitoring can accurately evaluate respiratory disturbance incidence during sedation for gastrointestinal endoscopy compare to pulse oximetry alone.METHODS This prospective observational study included 10 elderly patients with early gastric cancer undergoing endoscopic submucosal dissection(ESD) under propofol sedation. Apart from routine cardiorespiratory monitoring, polysomnography measurements were acquired. The primary hypothesis was tested by comparing the apnea hypopnea index(AHI), defined as the number of apnea and hypopnea instances per hour during sedation, with and without hypoxemia; hypoxemia was defined as the reduction in oxygen saturation by ≥ 3% from baseline.RESULTS Polysomnography(PSG) detected 207 respiratory disturbances in the 10 patients. PSG yielded a significantly greater AHI(10.44 ± 5.68/h) compared with pulse oximetry(1.54 ± 1.81/h, P < 0.001), thus supporting our hypothesis. Obstructive AHI(9.26 ± 5.44/h) was significantly greater than central AHI(1.19 ± 0.90/h, P < 0.001). Compared with pulse oximetry, PSG detected the 25 instances of respiratory disturbances with hypoxemia 107.4 s earlier on average.CONCLUSION Compared with pulse oximetry, PSG can better detect respiratory irregularities and thus provide superior AHI values, leading to avoidance of fatal respiratory complications during ESD under propofol-induced sedation. | Ryuma Urahama Masaya Uesato Mizuho Aikawa Yukiko Yamaguchi Koichi Hayano Tomoaki Matsumura Makoto Arai Reiko Kunii Shiroh Isono Hisahiro Matsubara | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，11： | 3 |
| 2 | Fluxes of carbon dioxide, methane and nitrous oxide in two contrastive fringing zones of coastal lagoon, Lake Nakaumi, Japan显示文摘 | Mitsuru Hirota Yukiko Senga Yasushi Seike Seiichi Nohara Hidenobu Kunii | 2007 | Chemosphere2007，，3： | 2 |
| 3 | Emerging Web Graphics Standards and Technologies 显示文摘 | Lau R W H Li F Kunii T L | 2003 | IEEE Computer Graphics and Applications2003，，1： | 1 |
| 4 | Preparation and antimmor characteris- tics ofPLA/ (PEG-PPG-PEG) nanoparticles loaded with camptothecin 显示文摘 | Kunii R Onishi H Machida Y | 2007 | Eur J Pharm Biopharm2007，67，1： | 1 |
| 5 | Singularity theoretical modeling and animation of garment wrinkle formation processes显示文摘 | Tosiyasu L. Kunii Hironobu Gotoda | 1990 | The Visual Computer1990，，6： | 1 |
| 6 | Circulating fluidized-bed reactors显示文摘 | Daizo Kunii Octave Levenspiel | 1997 | Chemical Engineering Science1997，，15： | 1 |
| 7 | Prevalence of malignant tu- mors and adenomatous lesions detected by ultrasonographic screening in patients with autoimmune thyroid disease显示文摘 | Mukasa K Neh J Y Kunii Y | 2011 | Thy- roid2011，21，1： | 1 |
| 8 | Small,light-weight rover 'Micro5' for lunar exploration显示文摘 | Kubota T Kuroda Y Kunii Y | 2003 | Acta Astronautica2003，52，26： | 1 |
| 9 | Rate of reduction of nitric oxide by char 显示文摘 | Kunii D Yamada N | 1980 | International Chemical Engineering1980，20，： | 1 |
| 10 | Plasma brain natriuretic peptide and the evaluation of volume overload in infants and children with congenital heart disease显示文摘 | Kunii Y Kamada M Ohtsuki S | 2003 | Acta Med Okayama2003，57，4： | 1 |
| 11 | Clinical significance of serum S100 beta protein level after pediatric cardiac surgery显示文摘 | Koide M Kunii Y Moriki N | 2002 | Jpn J Thoral Caroliorasc Surg2002，50，7： | 1 |
| 12 | A phase Ⅰ-Ⅱ study of α-galactosylceramide-pulsed IL-2/GM-CSF-cultured periph- eral blood mononuclear cells in patients with advanced and re- current non-small cell lung cancer显示文摘 | Motohashi S Nagato K Kunii N | 2009 | J Immunol2009，182，4： | 1 |
| 13 | EMERGENCY ABDOMINAL SURGERY FOR SIGMOID MESOCOLIC HERNIA显示文摘 | TAKASHI YOKOTA YASUO YAMADA YASUSUKE MURAKAMI MITSUHIKO YASUDA SHIN TESHIMA YASUO KUNII HIDEMI YAMAUCHI | 2002 | American Journal of Emergency Medicine2002，，2： | 1 |
| 14 | Studies on axial effective thermal conductivities in packed beds显示文摘 | Yagi S Kunii D Wakao N | 2004 | AIChE Journal2004，6，4： | 1 |
| 15 | Importance of considering nutrient loadings from small watersheds to a lake-A case study of the Lake Shinji watershed,Shimane Prefecture,Japan显示文摘Nutrient loadings from upstream watersheds can have significant impacts on the water quality of receiving water bodies.Usually,a major river is selected as the target for water quality studies,and the impact of minor rivers tends to be ignored.It is very important to evaluate whether the impact of small rivers on the downstream water quality is negligible.River water sampling and discharge modeling using SWAT were used to analyze the contribution of small rivers to water quality in a receiving lake.From this analysis,it was determined that the inflowing total nitrogen(TN)and total phosphorus(TP)concentrations from all target rivers exceeded the lake water environmental standards set by the Ministry of the Environment.The contribution of suspended sediment(SS)and TN loads from small rivers did not vary markedly compared with their relative discharge contributions to the lake,at approximately 20%.However,the impact on TP loads to the lake from small rivers was 9.1%higher than their relative flow contributions,accounting for 28.2% of the TP loading.Thus,there is a potential to underestimate the impact of ungauged small rivers if only the major river is selected to evaluate the downstream lake water quality. | Hiroaki Somura Hidenobu Kunii Yasumichi Yone Ikuo Takeda Hirokazu Sato | 2018 | International Journal of Agricultural and Biological Engineering2018，11，5： | 1 |
| 16 | Significant prognostic factors in patients with node-negative gastric cancer显示文摘 | Yokota T Kunii Y Teshima S Yamada Y Saito T Takahashi M Kikuchi S Yamauchi H | 1999 | Int Surg1999，84，4： | 1 |
| 17 | Model-based analysis of hand postur显示文摘 | Lee J Kunii T L | 1995 | Computer Graphics and Applications1995，15，5： | 1 |
| 18 | Asma brain natriuretic peptide and the evaluation of volume overload in infants and children with congenital heart disease显示文摘 | Kunii Y Kamada M Ohtsuki S | 2003 | Acta Med Okayama2003，57，4： | 1 |
| 19 | The homotopy model: a generalized model for smooth surface generation from cross sectional data显示文摘 | SHINAGAWA Y KUNII T L | 1991 | The Visual Gomputer1991，7，23： | 1 |
| 20 | Selection of DNA aptam- ers recognizing small cell lung cancer using living cell-SELEX 显示文摘 | Kunii T Ogura S Mie M Kobatake E | 2011 | Analyst2011，136，7： | 1 |
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