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| 1 | Novel association between sperm deformity index and oxidative stress-induced DNA damage in infertile male patients显示文摘Aim: To investigate the impact of abnormal sperm morphology using the sperm deformity index (SDI) on reactive oxygen species (ROS) production and its correlation with sperm DNA damage. Methods: Semen samples were collected from men undergoing infertility screening (n=7) and healthy donors (n=6). Mature spermatozoa were isolated and incubated with 5mmol/L β-nicotinamide adenine dinucleotide phosphate (NADPH) for up to 24h to induce ROS. Sperm morphology was evaluated using strict Tygerberg's criteria and the SDI. ROS levels and DNA damage were assessed using chemiluminescence and terminal deoxynucleotidyl transferase-mediated fluoresceindUTP nick end labeling (TUNEL) assays, respectively. Results: SDI values (median [interquartiles]) were higher in patients than donors (2 [1.8,2.1] vs. 1.53 [1.52, 1.58], P=0.008). Aliquots treated with NADPH showed higher ROS levels (1.22 [0.30, 1.87] vs. 0.39 [0.10, 0.57], P=0.03) and higher incidence of DNA damage than those not treated (10 [4.69, 24.85] vs. 3.85 [2.58, 5.10], P=0.008). Higher DNA damage was also seen following 24h of incubation in patients compared to donors. SDI correlated with the percentage increase in sperm DNA damage following incubation for 24h in samples treated with NADPH (r=0.7, P=0.008) and controls (r=0.58, P=0.04).Conclusion: SDI may be a useful tool in identifying potential infertile males with abnormal prevalence of oxidative stress (OS)-induced DNA damage. NADPH plays a role in ROS-mediated sperm DNA damage, which appears to be more evident in infertile patients with semen samples containing a high incidence of morphologically abnormalspermatozoa. | Tamer M.Said Nabil Aziz Rakesh K.Sharma Iwan Lewis-Jones AnthonyJ.ThomasJr AshokAgarwal | 2005 | Asian Journal of Andrology2005，7，2： | 10 |
| 2 | Influence of feeding crimped kernel maize silage on the course of subclinical necrotic enteritis in a broiler disease model显示文摘This experiment was carried out with 375 male broilers(Ross 308) from days 1 to 28 to evaluate the influence of crimped kernel maize silage(CKMS) on the manifestation of subclinical necrotic enteritis,microbiota counts, organic acid production and relative weights of gastrointestinal segments. A necrotic enteritis disease model was applied. Birds were allocated into 3 different dietary treatments: a maizebased feed(MBF, control diet), and 2 diets supplemented with 15%(CKMS15) or 30%(CKMS30) of crimped ensiled kernel maize. The disease model involved a 10-time overdose of an attenuated live vaccine against coccidiosis given orally on day 17, followed by oral inoculation of Clostridium perfringens Type A(S48,10~8 to 10~9 bacteria/bird) twice daily on days 18,19, 20 and 21. Scoring of intestinal lesions was performed on days 22, 23, 25 and 28. Ileal and caecal digesta samples were collected for the quantification of selected bacterial groups and organic acids. The results showed that there was no effect of dietary treatments on small intestinal lesion scores(P> 0.05). Lesions scores peaked on days 23 and 25 and decreased again on day 28(P = 0.001). No effect of age on microbiota counts was observed, but feeding of CKMS30 reduced the number of coliforms in ileal contents(P = 0.01). Dietary treatments did not affect organic acid concentrations in ileum and caeca, but there was an effect of age; butyric acid was higher on days 22, 23 and 25 than on day 28(P = 0.04). Acetic acid and propionic acid concentrations in caeca were the highest on days 22 and 28 but the lowest on days 23 and 25. Relative gizzard and caeca weights were increased, and relative ileum weights were decreased when birds were fed CKMS30(P < 0.05). In conclusion, the inclusion of CKMS in broiler diets had no effects on the course of necrotic enteritis but had potential benefits in terms of inhibition of potentially harmful microorganisms. | Nisha Sharma Samir Ranjitkar Nishchal K.Sharma Ricarda M.Engberg | 2017 | Animal Nutrition2017，，4： | 5 |
| 3 | 牛脑Ca^(2+)/CaM依赖性蛋白激酶Ⅱ的纯化和鉴定显示文摘通过一系列层析法,首次从牛脑纯化得到胶凝电泳匀一的Ca^(2+)/CaM PKⅡ。凝胶过滤法测定全酶分子量为550kD,SDS-PAGE法测定亚基分子量为55kD,推测牛脑Ca^(2+)/CaM PK Ⅱ由十个相同的亚基组成。该酶活性绝对依赖于Ca^(2+)和CaM,以63kD PDE同工酶为底物,其AC_(50)分别为0.85μmol/L和0.18μmol/L;以酪蛋白为底物,其AC_(50)分别为0.22μmol/L和0.06μmol/L。牛脑Ca^(2+)/CaM PK Ⅱ旣能催化63kD PDE同工酶等多种蛋白或酶磷酸化,又能进行自身磷酸化。该酶催化63kD PDE同工酶最大磷酸参入量为1mol/mol亚基。磷酸化型63kD PDE同工酶的Ca^(2+)的AC_(50)高于非磷酸化型。 | 张光毅 赵昇皓 Rajendra K.Sharma Jerry H.Wang | 1991 | 生物化学杂志1991，7，4： | 4 |
| 4 | Cognitive Radios: A Survey On Spectrum Sensing, Security and Spectrum Handoff显示文摘Pervasive wireless computing and communication have created an ever-increasing demand for more radio spectrum. Since, most of the spectrum is underutilized, it motivated the introduction of the concept of cognitive radios, a dynamic spectrum access enabling technology. The first stage of cognitive radio is to sense the environment and determine which parts of the spectrum are available. This is achieved through spectrum sensing. However, spectrum sensing poses the most fundamental challenge in cognitive radios. Moreover, cognitive radios suffer from many vulnerabilities and the security attacks can severely degrade the performance of cognitive radios. This paper surveys state-of-theart research on spectrum sensing and security threats in cognitive radios. Lastly, we also consider the analysis of issues related to spectrum handoffs in cognitive radios. | Vishakha Ramani Sanjay K.Sharma | 2017 | China Communications2017，14，11： | 4 |
| 5 | Graphene-based flexible and wearable electronics显示文摘Graphene with an exceptional combination of electronic, optical and outstanding mechanical features has been proved to lead a completely different kind of 2-D electronics. The most exciting feature of graphene is its ultra-thin thickness, that can be conformally contacted to any kind of rough surface without losing much of its transparency and conductivity. Graphene has been explored demonstrating various prototype flexible electronic applications, however, its potentiality has been proven wherever transparent conductive electrodes(TCEs) are needed in a flexible, stretchable format. Graphene-based TCEs in flexible electronic applications showed greatly superior performance over their conventionally available competitor indium tin oxide(ITO). Moreover, enormous applications have been emerging, especially in wearable devices that can be potentially used in our daily life as well as in biomedical areas. However, the production of high-quality, defect-free large area graphene is still a challenge and the main hurdle in the commercialization of flexible and wearable products. The objective of the present review paper is to summarize the progress made so far in graphene-based flexible and wearable applications. The current developments including challenges and future perspectives arc also highlighted. | Tanmoy Das Bhupendra K.Sharma Ajit K.Katiyar Jong-Hyun Ahn | 2018 | Journal of Semiconductors2018，39，1： | 4 |
| 6 | Performance,litter quality and gaseous odour emissions of broilers fed phytase supplemented diets显示文摘The effect of graded levels of phytase on performance, bone characteristics, excreta/litter quality and odorant emissions was examined using 720 Ross 308 male d-old broilers. A 2 x 4 factorial arrangement of treatments was employed with 6 replicates of 15 birds per pen. Factors were: diets-positive and negative control(PC, NC); phytase-0, 500,1,000.1,500 FTU/kg. The PC was formulated to meet the 2014 Ross 308 nutrient specifications, whereas the NC was formulated with lower Ca(-1.4 g/kg), available P(-1.5 g/kg), Na(-0.3 g/kg), dLys(-0.2 g/kg) and MEn(-0.28 MJ/kg) equivalent to nutrient matrix values for 500 FTU/kg phytase in the starter,grower and finisher periods(i.e.,downspec diet). On d 24, phytase decreased FCR by 1.6, 4.3 and 4.6 points at inclusion levels of 500.1,000 and 1,500 FTU/kg, respectively(P < 0.01) across all diets. Phytase by diet interactions on BW gain were observed on d 24 and 35(P < 0.01). The effect of phytase was much more pronounced in the NC diet as compared with the PC diet.On d 24, phytase increased BW gain by 37, 55 and 68 g in the PC and 127.233 and 173 g in the NC at 500,1,000 and 1,500 FTU/kg, respectively. Diet by phytase interactions were also observed for tibia ash, litter quality and water to feed intake ratio(P < 0.01) with higher phytase effect in NC as compared with PC.Neither diet nor phytase impacted excreta moisture content on d 18 or 21(P> 0.05). Solid phase microextraction gas chromatography-mass spectrometry(SPME-GC-MS) analysis of gaseous emissions on d 39 indicated no difference in the emission of alcohols, aldehydes, ketones, volatile fatty acids and phenols between treatments(P> 0.05). The results indicate that phytase has greater benefits when formulated using nutrient matrix values as compared with adding it over the top in an already nutrient sufficient diet. The later method would be expected to increase feed costs without concomitant performance benefits. | Nishchal K.Sharma Mingan Choct Shu-Biao Wu Robert Smillie Natalie Morgan Amal S.Omar Nisha Sharma Robert A.Swick | 2016 | Animal Nutrition2016，，4： | 3 |
| 7 | Effects of L-arginine and L-citrulline supplementation in reduced protein diets for broilers under normal and cyclic warm temperature显示文摘Heat stress causes significant economic losses in the broiler industry.Dietary supplementation of arginine(Arg)and citrulline(Cit)might increase the performance of broilers raised under warm temperature due to vasodilation effects.This study investigated the effects of L-Arg or L-Cit supplementation in broilers fed a reduced protein wheat-based diet deficient in Arg under thermoneutral(NT)and cyclic warm temperature(WT).Ross 308 cockerels(n=720)were randomly allocated to 4 dietary treatments with 12 replicates of 15 birds per pen from d 7 to 21.The 4 treatments were:normal protein(NP),i.e.,22.3%and 20.9%crude protein in grower and finisher,respectively;reduced protein(RP),i.e.,2.5%lower protein and deficient in Arg;and RP supplemented with 0.28%Arg(RP-Arg)or 0.28%Cit(RP-Cit).A factorial arrangement of treatments was applied during the finisher phase(21 to 35 d).Factors were:diet(4 diets above);and temperature,NT(24℃)or cyclic WT(33±1℃for 6 h per day)with 6 replicate pens per treatment.During 7 to 35 d and 21 to 35 d,the birds fed the RP diet had lower body weight gain(BWG)and higher FCR compared to the NP diet(P<0.01).The addition of Arg or Cit to RP decreased FCR compared to RP(P<0.01).During 21 to 35 d,the birds exposed to WT had lower feed intake(FI),lower BWG(P<0.001)but similar FCR(P>0.05)compared to birds exposed to NT.Diet by temperature interactions were not observed for performance parameters during the period of WT(P>0.05).On d 35,the RP-fed birds had a lower yield of thigh and drumstick,higher fat pad,lower femur ash,and breaking strength but similar serum uric acid level and higher nitrogen digestibility on d 21 compared to those offered NP(P<0.05).Supplementation of Arg or Cit to RP resulted in increased femur ash on d 35(P<0.05).Thus,feeding the NP diets is necessary to maintain growth performance in broilers regardless of the temperature conditions. | Hiep Thi Dao Nishchal K.Sharma Emma J.Bradbury Robert A.Swick | 2021 | Animal Nutrition2021，，4： | 3 |
| 8 | Dietary composition affects odour emissions from meat chickens显示文摘Abatement of odour emissions has become an important consideration to agricultural industries,including poultry production. The link between diet and odour emissions was studied in two experiments using Ross 308 male meat chickens reared in specially designed chambers in a climate controlled room. In the first experiment, two treatments were compared using three replicates of two birds per chamber. Two wheat-soy based treatment diets were formulated with or without canola seed, an ingredient rich in sulfur amino acids, Treatment 1(T1) had 13,39 MJ/kg ME(as fed) and used 60 g/kg canola seed without corn while Treatment 2(T2) contained 12.90 MJ/kg ME(as fed) and used 150 g/kg corn without canola seed. In the second experiment, birds were assigned to three dietary treatments of five replicates with five birds per replicate(chamber). The basal starter, grower and finisher diets in the control group(SBM group) contained soybean meal in the range of 227-291 g/kg(as fed) as the main protein source. The other treatments(CM and MBM groups) contained either high levels of canola meal(174-190 g/kg) or meat meal(74-110 g/kg) at the expense of soybean meal. In both experiments, diets were isocaloric, isonitrogenous and contained similar digestible amino acid contents as per 2007 Aviagen Ross 308 guidelines. Emissions of odour were measured using Fourier transform infrared(FTIR) spectroscopy. In both experiments, major odorous compounds detected included 2,3-butanedione(diacetyl),2-butanone, dimethyl disulfide, methyl mercaptan, ethyl mercaptan, 2-butanol, 3-methyl-butanal,phenol and m-cresol. In the first experiment, Tl(with canola seed) produced higher concentration of methyl mercaptan(P < 0.05) and lower diacetyl(P < 0.01) than T2. In the second experiment, methyl mercaptan emission was higher in SBM group(P = 0.01) and total elemental sulfur were higher in SBM and CM groups up to day 24(P < 0.01). Results of these experiments indicated a direct link between diet and odour emissions from meat chickens. | Nishchal K.Sharma Mingan Choct Shu-Biao Wu Robert Smillie Robert A.Swick | 2015 | Animal Nutrition2015，，1： | 2 |
| 9 | Slumping in the Upper Jurassic Baisakhi Formation of the Jaisalmer Basin, western India: Sign of synsedimentary tectonics?显示文摘A spectacularly exposed slump is described from a 120-m-long road cut between the villages of Kanod and Deva in the northeastern Jaisalmer Basin of Rajasthan,India.The Upper Jurassic part of the sediments at the outcrop was formed in a near-shore setting and belongs to the Ludharwa Member of the Baisakhi Formation.The 3-m-thick unit shows a number of asymmetric folds and thrust faults leading to an imbrication of partly lithified sandstone beds.The deformation structures allow the reconstruction of a movement towards the northwest.This agrees well with the basin configuration that shows a deepening into this direction.Although the determination of a specific trigger mechanism is difficult for soft-sediment deformation structures,an earthquake caused by synsedimentary tectonics in the basin seems to be the most likely explanation. | Matthias Alberti Dhirendra K.Pandey Jitendra K.Sharma Narendra K.Swami Alfred Uchman | 2017 | Journal of Palaeogeography2017，6，4： | 2 |
| 10 | Flavonoids: emerging trends and potential health benefits显示文摘Flavonoids are widely used in industry for the prevention of various diseases. In daily life we are directly in touch with flavonoids due to their presence in different beverages, fruits and vegetables. Flavonoids are mainly used as a coloring agent in plants, antioxidant and nutritional food for human. Flavonoids have explicit role in UV filtration, symbiotic nitrogen fixation and floral pigmentation. Flavonoids have potential for different biological activities like chelation of metals, decreasing platelets aggregation and cell signaling etc. | Raj K.Keservani Anil K.Sharma | 2014 | Journal of Chinese Pharmaceutical Sciences2014，23，12： | 2 |
| 11 | Drought-Tolerant Pseudomonas spp. Improve the Growth Performance of Finger Millet(Eleusine coracana(L.) Gaertn.)Under Non-Stressed and Drought-Stressed Conditions显示文摘Application of plant growth-promoting bacteria(PGPB)is an environmentally sustainable option to reduce the effects of abiotic and biotic stresses on plant growth and productivity.Three 1-aminocyclopropane-1-carboxylic acid(ACC)deaminase-producing drought-tolerant bacteria were isolated from a rain-fed agriculture field in the Central Himalaya of Kumaun region,Uttarakhand,India and evaluated for their efficiency in improving finger millet(Eleusine coracana(L.)Gaertn.)plant growth under non-stressed and drought-stressed conditions.These bacteria withstood a substrate metric potential of -1.0 MPa(30% polyethylene glycol 8000)and therefore were considered drought-tolerant.These strains were identified as Pseudomonas spp.by fatty acid methyl ester analysis and 16S rRNA gene sequencing.The ACC deaminase activity of these strains was characterized at the biochemical level,and the presence of acd S gene,the structural gene for ACC deaminase,was confirmed by the polymerase chain reaction.Two sets of pot trials in glass house were set up,one for normal(non-stressed)and the other for drought-stressed conditions.After 5 weeks,one set of plants was subjected to drought stress for 5 d,while the other set continued to be watered.The same growth parameters were recorded for both sets of plants after 40 d of plant growth.The results of pot trials showed that treatments inoculated with ACC deaminase-producing bacterial strains significantly improved the growth performance of finger millet plants and foliar nutrient content as compared to uninoculated treatments under both non-stressed and drought-stressed conditions.In addition,a significant increase in antioxidant activity was observed,wherein bacterial stain inoculation improved plant fitness by protecting it from oxidative damage induced by drought. | Dinesh CHANDRA Rashmi SRIVASTAVA Bernard R.GLICK Anil K.SHARMA | 2018 | Pedosphere2018，28，2： | 2 |
| 12 | Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment of drinking water: A mini review显示文摘Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) have been recognized as one of the biggest public health issues of the 21 st century. Both ARB and ARGs have been determined in water after treatment with conventional disinfectants. Ultraviolet (UV) technology has been seen growth in application to disinfect the water. However, UV method alone is not adequate to degrade ARGs in water. Researchers are investigating the combination of UV with other oxidants (chlorine, hydrogen peroxide (H2O2), peroxymonosulfate (PMS), and photocatalysts) to harness the high reactivity of produced reactive species (C1-, C1O -, Cl2-,-OH, and SO4-_) in such processes with constituents of cell (e.g., deoxyribonucleic acid (DNA) and its components) in order to increase the degradation efficiency of ARGs. This paper briefly reviews the current status of different UV-based treatments (UV/chlorination, UV/H2O2, UV/PMS, and UV-photocatalysis) to degrade ARGs and to control horizontal gene transfer (HGT) in water. The review also provides discussion on the mechanism of degradation of ARGs and application of q-PCR and gel electrophoresis to obtain insights of the fate of ARGs during UV-based treatment processes. | Virender K.Sharma Xin Yu Thomas J.McDonald Chetan Jinadatha Dionysios D.Dionysiou Mingbao Feng | 2019 | Frontiers of Environmental Science & Engineering2019，13，3： | 2 |
| 13 | NiCo2O4 decorated PANI–CNTs composites as supercapacitive electrode materials显示文摘Hierarchical Ni Co_2O_4/PANI/CNTs hybrid composites were designed and fabricated having a layer of Ni Co_2O_4 on the surface of PANI encapsulated CNTs with different morphologies. Physicochemical attributes of the synthesized composites were examined by FTIR, UV–visible and X-ray diffraction(XRD)techniques. Morphological aspects were evaluated by field-emission scanning microscopy(FESEM),electron diffraction spectroscopy(EDS), high resolution transmission electron microscopy(HRTEM) and selected area electron diffraction(SAED) studies. Electrochemical measurements revealed an improved specific capacitance of 2250 F/g at a scan rate of 5 m V/s and 2000 F/g at a current density of 1 A/g with good rate capability using a three-electrode system. These enhanced features are achieved from the well designed nanostructure and the synergistic contributions of individual components in the electrode material. | Gunjana Chaudhary Ashok K.Sharma Preetam Bhardwaj Kamal Kant Indu Kaushal Ajay K.Mishra | 2017 | Journal of Energy Chemistry2017，26，1： | 1 |
| 14 | Hypolipidaemic Effect of Fenugreek Seeds: a Chronic Study in Non‐insulin Dependent Diabetic Patients显示文摘 | R. D.Sharma A.Sarkar D. K.Hazra B.Misra J. B.Singh B. B.Maheshwari S. K.Sharma | 1998 | Phytother Res1998，，4： | 1 |
| 15 | Biotransformation of tea catechins into theaflavins with immobilized polyphenol oxidase显示文摘 | K.Sharma S.S.Bari H.P.Singh | 2009 | J Mol Catal B—Enzym2009，，04： | 1 |
| 16 | Evaluation of creep and shrinkage effects in composite tall buildings显示文摘 | PeeyushChowdhary Ravi K.Sharma | 2011 | Struct Design Tall Spec Build2011，，7： | 1 |
| 17 | Potential of a mixture of eugenol and garlic tincture to improve performance and intestinal health in broilers under necrotic enteritis challenge显示文摘Plant extracts(PE)are gaining increased attention as potential alternatives to in-feed antimicrobials(AM)due to their known antimicrobial activities.This study was conducted to examine the potential of PE,a microencapsulated product composed of eugenol and garlic tincture as an alternative to AM-agent on performance and intestinal health in broilers under necrotic enteritis(NE)challenge.A total of 960 dayold mixed-sex Cobb 500 chicks were randomly distributed to 48-floor pens with 6 treatments replicated 8 times with 20 birds each.The 6 treatments were as follows:UC,unchallenged control;CC,challenged control;PE,challenged group plus PE;AM,challenged group plus AM;FAP,challenged group plus a full dose of AM with PE;HAP,challenged group plus a half dose of AM with PE in starter,grower and finisher phases.Birds in the challenged groups were inoculated with Eimeria spp.on d 9 and Clostridium perfringens on d 14.The body weight gain(BWG),feed intake(FI),feed conversion ratio(FCR),and livability of birds were compromised,and intestinal lesions and mortality were increased(P<0.05)by NE challenge,illustrating a successful clinical NE challenge.Birds fed AM had higher BWG and FI,and lower FCR,mortality,and intestinal lesions compared to the CC group(P<0.05).Birds fed PE had improved FCR(P<0.05)and livability(5.8%)in an overall period compared to the CC group.On d 16,PE supplementation reduced ileal lesion scores in only male birds(P<0.05).Birds fed PE had decreased Eimeria maxima and Eimeria acervulina oocyst counts in caecal content(P<0.05).Birds fed PE had decreased Eimeria brunetti and total oocyst counts in caecal content,and E.acervulina oocyst counts in ileal content in only female birds(P<0.05).On d 35,PE supplementation reduced variation of BW in both male and female birds and increased yellowness(b*value,14.4%)in the thigh.These findings suggest the potential of PE supplementation in diets to improve the performance and intestinal health of birds under clinical NE as indicated by improved FCR,livability,uniformity,reduced ileal lesions,oocyst counts and increased skin yellowness.However,the protective effect of PE may not be apparent in the presence of AM in the feed. | Alip Kumar Nishchal K.Sharma Sarbast K.Kheravii Chake Keerqin Catherine Ionescu Alexandra Blanchard Shu-Biao Wu | 2022 | Animal Nutrition2022，，1： | 1 |
| 18 | Growth factor release from a chemically modified elastomeric poly(1,8‐octanediol‐co‐citrate) thin film promotes angiogenesis in vivo显示文摘 | Arun K.Sharma Matthew I.Bury Natalie J.Fuller Dorota I.Rozkiewicz Partha V.Hota David M.Kollhoff Matthew J.Webber NatalieTapaskar Jay W.Meisner Patrick J.Lariviere SamanthaDeStefano DeliWang Guillermo A.Ameer Earl Y.Cheng | 2012 | J Biomed Mater Res2012，，3： | 1 |
| 19 | Persistent free radicals in humin under redox conditions and their impact in transforming polycyclic aromatic hydrocarbons显示文摘The role of humic substance-associated persistent free radicals(PFRs)in the fate of organic contaminants under various redox conditions remains unknown.This study examined the characterization of original metal-free peat humin(HM),and HM treated with varying concentrations of H2O2 and L-ascorbic acid(VC)(assigned as H2O2-HM and VC-HM).The concentration of PFRs in HM increased with the addition of VC/H2O2 at concentrations less than 0.08 mol/L.The evolution of PFRs in HM under different environmental conditions(e.g.,oxic/anoxic and humidity)was investigated.Two types of PFRs were detected in HM:a relatively stable radical existed in the original sample,and the other type,which was generated by redox treatments,wa s relatively unstable.The spin densities of VC/H2O2-HM readily returned to the original value under relatively high humidity and oxic conditions.During this process,the HM-associated'unstable'free radicals released an electron to O2,inducing the formation of reactive oxygen species(ROS,i.e.,·OH and·O2-).Th e generated ROS promoted the degradation of polycyclic aromatic hydrocarbons based on the radical quenching measurements.The transformation rates followed the order naphthalene>phenanthrene>anthracene>benzo[a]pyrene.Our results provide valuable insight into the HM-induced transformation of organic contaminants under natural conditions. | Hanzhong Jia Yafang Shi Xiaofeng Nie Song Zhao Tiecheng Wang Virender K.Sharma | 2020 | Frontiers of Environmental Science & Engineering2020，14，4： | 1 |
| 20 | Carotid artery injury in endoscopic endonasal surgery: Risk factors, prevention, and management显示文摘Objective:Endoscopic approaches for sinus and skull base surgery are increasing in popularity.The objective of this narrative review is to characterize risk factors for internal carotid artery injury in endoscopic endonasal surgery(EES),highlight preventative measures,and illustrate key management principles.Data Sources:Comprehensive literature review.Methods:Relevant literature was reviewed using PubMed/MEDLINE.Results:Carotid artery injury in EES is rare,with most studies reporting an incidence below 0.1%.Anatomic aberrancies,wide dissection margins,as well as specific provider and hospital factors,may increase the risk of injury.Multidisciplinary teams,comprehensive preoperative imaging,patient risk assessment,and formal training in vascular emergencies may reduce the risk.Management protocols should emphasize proper visualization of the injury site,fluid replacement,rapid packing,angiography,and endovascular techniques to achieve hemostasis.Conclusions:While EES is a relatively safe procedure,carotid artery injury is a devastating complication that warrants full consideration in surgical planning.Important preventative measures include identifying patients with notable risk factors and obtaining preoperative imaging.Multidisciplinary teams and management protocols are ultimately necessary to reduce morbidity and mortality. | Rahul K.Sharma Alexandria L.I race Jonathan B.Overdevest David A.Gudis | 2022 | World Journal of Otorhinolaryngology-Head and Neck Surgery2022，8，1： | 1 |
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