| 1 | Potential of a mixture of eugenol and garlic tincture to improve performance and intestinal health in broilers under necrotic enteritis challenge显示文摘Plant extracts(PE)are gaining increased attention as potential alternatives to in-feed antimicrobials(AM)due to their known antimicrobial activities.This study was conducted to examine the potential of PE,a microencapsulated product composed of eugenol and garlic tincture as an alternative to AM-agent on performance and intestinal health in broilers under necrotic enteritis(NE)challenge.A total of 960 dayold mixed-sex Cobb 500 chicks were randomly distributed to 48-floor pens with 6 treatments replicated 8 times with 20 birds each.The 6 treatments were as follows:UC,unchallenged control;CC,challenged control;PE,challenged group plus PE;AM,challenged group plus AM;FAP,challenged group plus a full dose of AM with PE;HAP,challenged group plus a half dose of AM with PE in starter,grower and finisher phases.Birds in the challenged groups were inoculated with Eimeria spp.on d 9 and Clostridium perfringens on d 14.The body weight gain(BWG),feed intake(FI),feed conversion ratio(FCR),and livability of birds were compromised,and intestinal lesions and mortality were increased(P<0.05)by NE challenge,illustrating a successful clinical NE challenge.Birds fed AM had higher BWG and FI,and lower FCR,mortality,and intestinal lesions compared to the CC group(P<0.05).Birds fed PE had improved FCR(P<0.05)and livability(5.8%)in an overall period compared to the CC group.On d 16,PE supplementation reduced ileal lesion scores in only male birds(P<0.05).Birds fed PE had decreased Eimeria maxima and Eimeria acervulina oocyst counts in caecal content(P<0.05).Birds fed PE had decreased Eimeria brunetti and total oocyst counts in caecal content,and E.acervulina oocyst counts in ileal content in only female birds(P<0.05).On d 35,PE supplementation reduced variation of BW in both male and female birds and increased yellowness(b*value,14.4%)in the thigh.These findings suggest the potential of PE supplementation in diets to improve the performance and intestinal health of birds under clinical NE as indicated by improved FCR,livability,uniformity,reduced ileal lesions,oocyst counts and increased skin yellowness.However,the protective effect of PE may not be apparent in the presence of AM in the feed. | Alip Kumar Nishchal K.Sharma Sarbast K.Kheravii Chake Keerqin Catherine Ionescu Alexandra Blanchard Shu-Biao Wu | 2022 | Animal Nutrition2022，，1： | 1 |
| 2 | Organic acid blends improve intestinal integrity,modulate short-chain fatty acids profiles and alter microbiota of broilers under necrotic enteritis challenge显示文摘Controlling enteric diseases of broilers is crucial.Among many additives,organic acids(OA)and their blends are gaining attention to combat diseases in the post-antibiotic era.The current study evaluated the potentials of short-chain fatty acids(SCFA)and medium-chain fatty acids(MCFA)blends and/or phenolic compounds on intestinal integrity,intestinal pH,caecal microbiota,and caecal SCFA profiles of broilers under necrotic enteritis(NE)challenge.The additives used were:(A)a blend of SCFA,MCFA,and a phenolic compound(SMP),(B)a blend of free and buffered SCFA with MCFA(SMF),and(C)a blend of free and buffered SCFA with a high concentration of MCFA(SHM).A total of 1,404 male parental chicks of Ross 308 broilers were randomly allocated to 78 floor pens on hatching day with 6 treatments replicated 13 times with 18 birds per pen.The treatments were:UCC,unchallenged control;CHC,challenged control;BAC,challenged group plus zinc bacitracin;SMP,challenged group plus additive SMP;SMF,challenged group plus additive SMF;SHM,challenged group plus additive SHM.Birds were challenged with field-strain Eimeria spp.on d 9 and Clostridium perfringens on d 14.Birds challenged with NE increased fluorescein isothiocyanate dextran(FITC-d)concentration in serum,reduced acetate and butyrate concentrations,and increased Bacteroides and C.perfringens load in the caeca(P<0.05).Birds fed additives decreased FITC-d from gut to serum,reduced Bacteroides(d 16,P<0.05)and numerically reduced C.perfringens load compared to CHC group.Birds fed additive SHM had higher concentrations of acetate and butyrate(d 21,P<0.05)than CHC group but were not different from SMP and SMF groups.All the additives exhibited similar intestinal protection against NE compared to the BAC group indicated by FITC-d concentration in serum,acetate,propionate and butyrate concentrations in the caeca,and caecal bacterial loads except for the C.perfringens(P>0.05).The SMP group had a higher load compared to BAC(P<0.05).These findings suggest the promising effects of OA blends as alternatives to BAC to ameliorate the impact of NE challenge of broilers as indicated by improved intestinal health. | Alip Kumar Mehdi Toghyani Sarbast K.Kheravii Lane Pineda Yanming Han Robert A.Swick Shu-Biao Wu | 2022 | Animal Nutrition2022，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员