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| 1 | 湖南茶油中脂肪酸及活性成分研究显示文摘目的建立紫外分光光度法快速检测湖南本地油茶(Camellia oleifera Abel.)茶籽油中多酚、总黄酮和消光系数的分析方法。方法搜集30批次油茶籽油,建立紫外分光光度法测定油茶籽油的总黄酮值、多酚含量和消光系数,参照食品安全国家标准,测定油茶籽油中11种脂肪酸成分。结果确定紫外分光光度法不同参数指标中茶油待测样品的最大吸收波长,油茶籽油的总黄酮值含量在0.02~8.32 mg/kg范围之间、多酚含量在7.08~34.63 mg/kg范围之间,消光系数在0.135~1.445范围之间。11种脂肪酸组成中比例最高的3项依次是油酸、亚油酸和棕榈酸,不饱和脂肪酸比例超过86%。结论建立紫外分光光度快速检测法,有助于对油茶籽油质量分级及定向功能性筛选,适宜工厂实时监测和化妆品研发数据参考;对主要脂肪酸进行动脉粥样硬化指数(atherogenic index,AI)和血栓形成指数(thrombosis index,TI)两项营养指数评价,油茶籽油造成心血管的风险很低,具有良好的油用价值;为湖南茶油生产与加工过程中质量安全控制及高附加值产品的研发提供了一定的基础数据。 | 岳超 喻宁华 李红爱 佘佳荣 周文化 李梓铭 | 2021 | 食品安全质量检测学报2021，12，5： | 13 |
| 2 | Phenolic constituents from the root bark of Morus alba with emphasis on morusin and its anti-cancer properties显示文摘The root bark of Morus alba L. or white mulberry is widely used as traditional medicine in China, Japan and Korea. Major classes and types of phenolic compounds isolated from the root bark are flavonoids(kuwanons, morusin, cyclomorusin and sanggenons), benzofurans(moracins and mulberrofurans), and stilbenoids(mulberrosides). Some of the flavonoids and benzofurans are products of Diel-Alder type adducts. Other classes of compounds include triterpenes, phenolic acids and coumarins. Morusin, a prenylated flavonoid, was first isolated from the root bark of M. alba, and later from the leaf, stem bark and twig of the plant. The potent anti-cancer properties of morusin have attracted much attention with research on-going and new findings being published. The compound inhibits angiogenesis, tumour progression and tumour migration, and triggers apoptosis, cell cycle arrest and autophagy in colorectal, cervical, prostate, breast, hepatoma, pancreatic, glioblastoma, gastric, ovarian and lung cancer cell lines. The anti-cancer activities of morusin are executed via various molecular targets and signalling pathways. It is anticipated that on-going in vitro studies will progress gradually to in vivo studies using animal models before efforts towards drug development can be initiated for clinical trials. | Eric Wei Chiang Chan Siu Kuin Wong Tomomi Inoue Hung Tuck Chan | 2019 | Journal of Chinese Pharmaceutical Sciences2019，28，2： | 3 |
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