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| 1 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 2 | 四川黄龙沟天然水中的深源CO_2与大规模的钙华沉积显示文摘在有大规模钙华沉积的四川黄龙沟中,使用化学成分数据以及碳氧稳定同位素组成对其水文地球化学特征进行了分析研究。研究区钙华沉积的地表溪流水质基本上受到两种水混合的制约,即断层泉水和山区的融雪(冰)水。泉水中含有高浓度的经由断层提供的CO2,结果高浓度的溶解CO2使得其溶解的碳酸盐岩比普通的岩溶泉溶解的碳酸盐岩高得多,同时也导致硅酸盐岩的溶解。黄龙沟中上游的泉水相对于方解石接近于平衡。溶解无机碳(DIC)的浓度和它们的δ13C值是大约由c=0.02mol·L1δ13C=-3‰的CO2(aq)与含有δ13C=+3‰的碳酸盐岩在封闭系统条件下反应的结果。估计这些CO2中约有70%来自上地幔。所有泉水的水化学数据均落在高岭石稳定域内,但对Na长石和Ca长石具有侵蚀性。由于这些长石矿物的溶解速率太慢,所以水中的化学成分远离长石稳定域。地表溪流的DIC种类之间达到同位素平衡,在不同观测点发现的δ13CDIC变化主要是由于从水中释放出的CO2的程度不同引起的。水样的δ18O值与其采集点的海拔高度之间存在线性关系;研究区的地表溪流的氧同位素组成受到蒸发的制约。在流经钙华沉积物的地表溪流中白天和夜晚的水化学及pH的日变化表明生物作用促进了碳酸盐的沉积,尽管作用不显著。据估计研究区碳酸钙的日沉积速率是4778kg·km2,即约1mm·a1。 | 刘再华 K Yoshimura Y Inokura M Noto 曹云 | 2005 | 地球与环境2005，33，2： | 17 |
| 3 | Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke:an updated systematic review显示文摘The optimal dose of recombinant tissue plasminogen activator(rtPA)for acute ischaemic stroke(AIS)remains controversial,especially in Asian countries.We aimed to update the evidence regarding the use of low-dose versus standard-dose rtPA.We performed a systematic literature search across MEDLINE,Embase,Cochrane Central Register of Controlled Trials(CENTRAL),PsycINFO and Cumulative Index to Nursing and Allied Health Literature(CINAHL)from inception to 22 August 2016 to identify all related studies.The outcomes were death or disability(defined by modified Rankin Scale 2-6),death,and symptomatic intracerebral haemorrhage(sICH).Where possible,data were pooled for meta-analysis with ORs and corresponding 95% CIs by means of random-effects or fixed-effects meta-analysis.We included 26 observational studies and 1 randomised controlled trial with a total of 23210 patients.Variable doses of rtPA were used for thrombolysis of AIS in Asia.Meta-analysis shows that low-dose rtPA was not associated with increased risk of death or disability(OR 1.13,95% CI 0.95 to 1.33),or death(OR 0.86,95% CI 0.74 to 1.01),or decreased risk of sICH(OR 1.06,95% CI 0.65 to 1.72).The results remained consistent when sensitivity analyses were performed including only low-dose and standard-dose rtPA or only Asian studies.Our review shows small difference between the outcomes or the risk profile in the studies using low-dose and/or standard-dose rtPA for AIS.Low-dose rtPA was not associated with lower risk of death or disability,death alone,or sICH. | Xia Wang Shoujiang You Shoichiro Sato Jie Yang Cheryl Carcel Danni Zheng Sohei Yoshimura Craig S Anderson Else Charlotte Sandset Thompson Robinson John Chalmers Vijay K Sharma | 2018 | Stroke & Vascular Neurology2018，3，1： | 10 |
| 4 | A therapeutic strategy based on histological assessment of hyperpigmented skin lesions in Asians 显示文摘 | Kurita M Kato H Yoshimura K | 2008 | Plast Reconstr Aesthet Surg2008，19，： | 1 |
| 5 | The mitochondrial type II peroxiredoxin F is essential for redox homeostasis and mot growth of Arabidopsis thaliana under stress显示文摘 | YOSHIMURA K MIYAO K GABER A | 2004 | Journal of Biological Physics2004，37，： | 1 |
| 6 | Hydrothermal synthesis of biocompatible whisker显示文摘 | Suda H Okamoto K | 1994 | J Mater Sci1994，29，13： | 1 |
| 7 | In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium显示文摘 | Rosenfeld MA Yoshimura K Trapnell BC | 1992 | Cell1992，68，1： | 1 |
| 8 | Micro determination of Chromium,iron,copper and cobalt in water显示文摘 | Yoshimura K Waki H Ohashi S | 1976 | Talanta1976，23，： | 1 |
| 9 | Gelation behaviour of konjac glucomannan with different molecular weights显示文摘 | Zhang H Yoshimura M Nishinari K et ai | 2001 | Biopolymers2001，59，1： | 1 |
| 10 | Rheological studies on mixtures of corn starch andkonjac-glucomannan显示文摘 | YOSHIMURA M TAKAYA T NISHINARI K | 1998 | Carbohydrate Polymers1998，35，12： | 1 |
| 11 | High resistive ferrite films by a solution process for electromagnetic compatible(EMC)devices显示文摘 | SUBRAMANI A K KONDO K TADA M ABE M YOSHIMURA M MATSUSHITA N | 2009 | J Magn Magn Mater2009，321，： | 1 |
| 12 | Basic fibroblast growth factor regulates matrix metalloproteinases production and in vitro invasiveness in human bladder cancer cell lines 显示文摘 | Miyake H Yoshimura K Hara I | 1997 | J Urol1997，157，6： | 1 |
| 13 | Experimental studies on Bond Strength in concrete Filled square and octagonal steel Tubular columns subject to Axial loads显示文摘 | Morishira Y Tomii M Yoshimura K | 1979 | Transactions of japan concrete Institute1979，，1： | 1 |
| 14 | Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct 显示文摘 | Yoshimura Y Ohashi H Subedi K | 2006 | J Reprod Dev2006，52，2： | 1 |
| 15 | A new coal flash pyrolysis method utilizing effective radical transfer from solvent to coal显示文摘 | MIURA K MAE K ASAOKA S YOSHIMURA T HASHIMOTO K | 1991 | Energy Fuels1991，5，2： | 1 |
| 16 | Eosinophiis in the cerebrospinal fluid of mice infected with Angiostrongylus eantonensis ale resistant to apeptosis显示文摘 | Sugaya H Abe T Yoshimura K | 2001 | Int J Parasitol2001，31，14： | 1 |
| 17 | Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells 显示文摘 | Yoshimura K Sato K Aoi N | 2008 | Dermatol Surg2008，34，9： | 1 |
| 18 | A case of late-onset Tourette's disorder successfully treated with aripiprazole:View from blood levels of catecholamine metabolites and brain-derived neurotrophic factor (BDNF)显示文摘 | Ikenouchi-Sugita A Yoshimura R Hayashi K | 2009 | World Journal of Biological Psychiatry2009，10，43： | 1 |
| 19 | A multiple cross-sectional shape optimization method for automotive body frames显示文摘 | YOSHIMURA M NISHIWAKI S IZUI K | 2005 | Journal of Mechanical Design2005，127，1： | 1 |
| 20 | Construction of pigrnented skin equivalent and its application to the study of congenital disorders of pigmentation显示文摘 | Okazaki M Suzuki Y Yoshimura K | | 0，，06： | 1 |
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