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138篇 您的检索式：作者名="Juo"

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	题名	作者	年代	出处	被引量
1	Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia显示文摘AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: Long interspersed nucleotide element 1(LINE-1) methylation levels were used to surrogate genome-wide methylation level. We first tested for the association between high myopia(<-6 D) and LINE-1 methylation in leukocytes in 220 cases and 220 control subjects. Secondly, we validated the results of LINE-1 methylation in eyes from the form deprivation myopia(FDM) mice. Furthermore,we calculated the correlation of LINE-1 methylation levels between leukocyte DNA and ocular DNA in the mice. We also tested whether dopamine can alter LINE-1 methylation levels. RESULTS: The LINE-1 methylation level was significantly higher in the myopic human subjects than controls. The upper and middle tertiles of the methylation levels increased an approximately 2-fold(P≤0.002) risk for myopia than the lower tertile. Similarly, FDM mice had high LINE-1 methylation levels in the leukocyte, retina and sclera, and furthermore the methylation levels detected from these three tissues were significantly correlated. Immunohistochemical staining revealed higher levels of homocysteine and methionine in the rodent myopic eyes than normal eyes. Dopamine treatment to the cells reduced both LINE-1 methylation and DNA methyltransferase levels. CONCLUSION: LINE-1 hypermethylation may be associated with high myopia in human and mice. Homocysteine and methionine are accumulated in myopic eyes, which may provide excess methyl group for genome-wide methylation.	Edward Hsi Yung-Song Wang Chia-Wei Huang Ming-Lung Yu Suh-Hang Hank Juo Chung-Ling Liang	2019	International Journal of Ophthalmology(English edition)2019，12，1：	4
2	Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor显示文摘	Anne Brunet Azad Bonni Michael J Zigmond Michael Z Lin Peter Juo Linda S Hu Michael J Anderson Karen C Arden John Blenis Michael E Greenberg	1999	Cell1999，，6：	2
3	Leaching of fertilizer ions in a Ultisol from the high rainfall tropics: Leaching through undisturbed soil columns显示文摘	Pleysier JL Juo ASR	1981	Soil Science Society of America Journal1981，45，4：	1
4	Promoter polymorphisms of hepatic lipase gene influence HDL(2) but not HDL(3) in African American men:CARDIA study显示文摘	Han Z Smith JD	2001	J Lipid Res2001，42，2：	1
5	Comparison of the handheld Retinomax K-Plus2 and on-table autokeratometers in children with and without cycloplegia显示文摘	Chung-Ling Liang Kuo-Sheng Hung Naeun Park Patrick Chan Suh-Hang H Juo	2004	Journal of Cataract & Refractive Surgery2004，，3：	1
6	caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis显示文摘	Qi H Juo P Masuda-Robens J	2001	Cell Growth Differ2001，12，12：	1
7	phosphate sorption isotherm for evaluating the phosphate requirement of soils显示文摘	Juo A S R Fox R L	1970	Soil Science Society of American Journal1970，34，：	1
8	ITPKC single nucleotide polymor- phism associated with the Kawasaki disease in a Taiwanese popula- tion显示文摘	Kuo HC Yang KD Juo SH	2011	PLoS One2011，6，17：	1
9	Comparison of measurements of refractive errors between the hand-held Retinomax and on-table autorefractors in cyclopleged and noncyclopleged children显示文摘	Chung-Ling Liang Kuo-Sheng Hung Naeun Park Patrick Chan Suh-Hang Hank Juo	2003	American Journal of Ophthalmology2003，，6：	1
10	FADD is required for multiple signaling events downstream of the receptor Fas显示文摘	Juo P Woo MS Koo CJ	1999	Cell Growth Difer1999，10，12：	1
11	CASP3 gene single-nucleotide poly- morphism rs726892362 and Kawasaki disease in Taiwanese children 显示文摘	Kuo HC Yu HK Juo SH	2011	J Hum Genet2011，56，2：	1
12	leaching through undisturbed soil columns显示文摘	PLEYSIER J L JUO A S R Leaching of fertilizer ions in a Ultisolfromthe high rainfall tropics	1981	Soil Science Society of America Journal1981，45，：	1
13	A follow-up linkage study supports evidence for a bipolar affective disorder locus on chromosome 21q22 显示文摘	LIU J J JUO S H TERWILLIGER J D	2001	A- merican Journal of Medical Genetics2001，105，2：	1
14	A synthesis of taxusin显示文摘	Holton R A Juo R R Kim H B	1988	J Am Chem Soc1988，110，19：	1
15	CASP3 gene single-nu- eleotide polymorphism (rs72689236) and Kawasaki dis- ease in Taiwanese children显示文摘	Kuo HC Yu HR Juo SH	2011	J Hum Genet2011，56，2：	1
16	Crossability percentages of bread wheat landraces Sichuan province with rye显示文摘	Juo M C Yen C Yang J L	1992	Euphytica1992，61，：	1
17	Nutrient profile in a tropical Alfisol under conventional and no-till systems显示文摘	Juo A S R LaI R	1979	Soil Science1979，127，3：	1
18	Fas activation of the P38 mitogen-activated protein kinase signalling pathway requires ICE/ CED'3 family proteases显示文摘	Juo P Kuo CJ Reynolds SE	1997	Mol Cell Biol1997，17，1：	1
19	A single extraction method using silverthiourea for measuring exchangeable cations and effective CEC in soils with variable charges显示文摘	Pleysier J L Juo A S R	1980	Soil Science1980，129，4：	1
20	Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth显示文摘	Sher YP Chang CM Juo CG	2013	Oncogene2013，32，9：	1

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