|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Circulating microRNA expression profile: a novel potential predictor for chronic nervous lesions显示文摘长期的神经病的疼痛的机制不是清楚的。浆液 microRNAs (miRNAs ) 可能为长期的紧张的损害显示出一个特殊特征。然而,很少为神经病的疼痛在传播 miRNAs 对变化被知道。因此,在传播 miRNAs 表示侧面变化因为神经病的疼痛被调查。在针的神经结扎(SNL ) 外科,和 microarray 分析被执行在 miRNA 表示侧面决定变化前后,浆液从老鼠被收集。在从一样的个人的浆液的煽动性的 cytokines 的表示包括 interleukin-6 (IL-6 ) ,肿瘤坏死因素 --(TNF-) ,并且单核白血球趋化性的 protein-1 (MCP-1 ) ,也被测量。结果证明 IL-6, TNF- ,和 MCP-1 的表示层次显著地在显著地与疼痛层次被相关的 SNL 老鼠被提高。有在 SNL 外科前后的显著地不同的表示层次的九 miRNAs 被 microarray 分析识别,它被量的即时聚合酶链反应分析进一步验证。与没有 SNL 外科的天真的老鼠相比,在在 SNL 外科以后的老鼠的浆液的五 miRNAs ( hsa-miR-221 , hsa-miR-34c , hsa-miR-21 , hsa-miR-30a-5p ,和 hsa-miR-206 )的表示被减少,四 miRNAs ( hsa-miR-31-5p , hsa-miR-133b , hsa-miR-22 ,和 hsa-miRPlus-A1087 )被增加,建议变化可以在神经病的疼痛的规定包含的那 miRNA 。TargetScan 被用来为这些 miRNAs 预言 mRNA 目标,并且结果证明有多重预言的目标地点的抄本属于神经病学地重要的小径。生物信息学分析表明几目标基因与房间发信号的激活有关与紧张的损害联系了。在这研究,在在神经病的疼痛条件下面的浆液的 miRNA 侧面的变化第一次被显示出,建议在浆液的那传播 miRNAs 侧面是为神经病的疼痛的一个潜在的预言者。 | Yongming Xu Xin Zhang Shaofeng Pu Junzhen Wu Yingying Lv Dongping Du | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 4 |
| 2 | Anti-nociceptive roles of the glia-specific metabolic inhibitor fluorocitrate in paclitaxel- evoked neuropathic pain显示文摘 | Yongming Xu Guangxia Cheng Yanrong Zhu Xin Zhang Shaofeng Pu Junzhen Wu Yingying Lv Dongping Du | 2016 | Acta Biochimica et Biophysica Sinica2016，48，10： | 3 |
| 3 | Molecular design revitalizes the low-cost PTV-polymer for highly efficient organic solar cells显示文摘Developing photovoltaic materials with simple chemical structures and easy synthesis still remains a major challenge in the industrialization process of organic solar cells(OSCs).Herein,an ester substituted poly(thiophene vinylene)derivative,PTVT-T,was designed and synthesized in very few steps by adopting commercially available raw materials.The ester groups on the thiophene units enable PTVT-T to have a planar and stable conformation.Moreover,PTVT-T presents a wide absorption band and strong aggregation effect in solution,which are the key characteristics needed to realize high performance in non-fullerene-acceptor(NFA)-based OSCs.We then prepared OSCs by blending PTVT-T with three representative fullerene-and NF-based acceptors,PC71 BM,IT-4 F and BTP-e C9.It was found that PTVT-T can work well with all the acceptors,showing great potential to match new emerging NFAs.Particularly,a remarkable power conversion efficiency of 16.20%is achieved in a PTVT-T:BTP-e C9-based device,which is the highest value among the counterparts based on PTV derivatives.This work demonstrates that PTVT-T shows great potential for the future commercialization of OSCs. | Junzhen Ren Pengqing Bi Jianqi Zhang Jiao Liu Jingwen Wang Ye Xu Zhixiang Wei Shaoqing Zhang Jianhui Hou | 2021 | National Science Review2021，8，8： | 3 |
| 4 | Study on the Treatment of Acid Mine Drainage Containing Fe^(2+) and Mn^(2+) Using Modified Spontaneous Combustion Gangue显示文摘The high concentrations of Fe^(2+) and Mn^(2+) in acid mine drainage make it difficult and expensive to treat.It is urgent that we find a cheap and efficient adsorption material to treat Fe^(2+) and Mn^(2+).As a solid waste in mining areas,coal gangue occupies a large area and pollutes the surrounding environment during the stacking process.Developing a method of resource utilization is thus a research hotspot.In this study,we modified spontaneous combustion gangue using NaOH,NaCl,and HCl by chemically modifying the minerals.We determined the optimal conditions for treating Fe^(2+) and Mn^(2+) in acid mine drainage with spontaneous combustion gangue and modified coal gangue using the single factor test method.Based on results of the static test,two dynamic test columns,column No.1(spontaneous combustion gangue)and column No.2(NaOH modified spontaneous combustion gangue),were constructed,and the repair effects of acid mine drainage were compared and analyzed using dynamic experiments.The results show that overall,NaOH modified spontaneous combustion gangue is the most efficient at removing the Fe^(2+) and Mn^(2+) in acid mine drainage.The optimal conditions for NaOH modification are an NaOH concentration of 3 mol/L,a liquid to solid ratio of 2 L/kg,and a modification time of 8 h.The overall efficiency of column No.2 at removing Fe^(2+) and Mn^(2+) from acid mine drainage is better than that of column No.1.Among them,the average removal efficiency of Fe^(2+)and Mn^(2+) from acid mine drainage in column No.2 were 97.73%and 44.82%,respectively.The above results show that NaOH modified spontaneous combustion gangue is a good adsorbent,which has application potential in wastewater remediation,as it can achieve the purpose of“treating dust with waste”. | Xuying Guo Saiou Fu Junzhen Di Yanrong Dong Guoliang Jiang | 2021 | Journal of Renewable Materials2021，9，3： | 2 |
| 5 | The Dynamic Experiment on Treating Acid Mine Drainage with Iron Scrap and Sulfate Reducing Bacteria Using Biomass Materials as Carbon Source显示文摘The study is aimed at the problem of high content of Cr^(6+),Cr^(3+)and SO_(4)^(2-)is high and low pH value in acid mine drainage(AMD).Moreover,treatment of AMD by sulfate reducing bacteria(SRB)requires the addition of carbon source,while the treating effectiveness is not good enough on its own.The sugarcane slag,the corn cob and the sunflower straw were selected as the SRB carbon source cooperating with iron scrap to construct the dynamic columns 1,2 and 3.The mechanism of removing Cr^(6+),Cr^(3+),SO_(4)^(2-)and H+and the regularity of sustained release of carbon source and TFe release was studied in AMD.The removal efficiency of heavy metal ions,the ability of sustained release of carbon source,and the ability of adjusting acid by the three dynamic columns were compared.The result shows that the average removal rates of Cr^(6+),Cr^(3+)and SO_(4)^(2-)in effluent of dynamic column 1,filled by sugarcane slag,iron scrap and SRB,were 96.9%,67.1%and 54.3%.The average release of TFe and chemical oxygen demand(COD)were 4.4 and 287.3 mg/L.Its average pH was 6.98.Compared with the performance of dynamic columns 1,2 and 3,dynamic column 1 performed best in removing Cr^(6+),Cr^(3+)and SO_(4)^(2-)from AMD and controlling the release of COD and TFe,adjusting the pH of the solution.The study is of significance in treatment of AMD by taking for biomass materials as SRB carbon source in cooperation with iron scrap. | Xianjun Wang Junzhen Di Yanrong Dong Yu Yang Bing Liang Fankang Meng Tingting Wang Wenbo An Zengxin Li Jianzhi Guo | 2021 | Journal of Renewable Materials2021，9，1： | 2 |
| 6 | Progress in Organic Solar Cells: Materials, Physics and Device Engineering显示文摘Organic solar cells(OSCs)have been developed for few decades since the preparation of the first photovoltaic device,and the record power conversion efficiency(PCE)certified by national renewable energy laboratory(NREL)has exceeded 17%.Looking back the whole history of OSCs,its rapid development is inseparable from multi-disciplinary efforts,including the new materials synthesizing,the device physics,and the device engineering,especially the breakthroughs in these disciplines.In this review,we are aiming at reviewing the history of the development of OSCs and summarizing the representative breakthroughs. | Pengqing Bi Shaoqing Zhang Jingwen Wang Junzhen Ren Jianhui Hou | 2021 | Chinese Journal of Chemistry2021，39，9： | 2 |
| 7 | Quantitative Evaluation of Fatigue Crack Size Using Eddy Current Pulsed Thermography显示文摘A set of metallic specimens containing fatigue cracks with different sizes were tested using eddy current pulsed thermography(ECPT),therefore the relations between heating response of the crack area and the crack length was studied.The numerical and experimental results both showed that the increase of the crack length enhanced the crack heating response under specific test conditions.A particular form of calculated response signal,which is linearly related to the crack length,was introduced to provide a quantitative evaluation of crack length. | Feng Fuzhou Xu Chao Zhu Junzhen Min Qingxu Sun Jiwei | 2017 | Transactions of Nanjing University of Aeronautics and Astronautics2017，34，3： | 1 |
| 8 | Aggregation and conformational changes of bovine fl-lactoglobulin subjected to dynamic high pressure microfluidization in relation with antigenicity显示文摘 | ZHONG Junzhen LIU Wei LIU Chengmei | 2012 | Journal of Dairy Science2012，95，8： | 1 |
| 9 | Tamoxifen attenuates reactive astrocyte-induced brain metastasis and drug resistance through the IL-6/STAT3 signaling pathway显示文摘Brain metastasis affects approxim ately 20%-30%of patients w ith triple-negative breast cancers(TNBCs).Even sm all metastatic lesions in the brain can trigg er severe neurological im pairm ents and result in extrem ely short survival time.Recently,active astrocytes were reported to be associated w ith brain metastases.However,how activated astrocytes regulate the behaviors of disseminated breast cancer cells in the brain remains unknown.In this study,human prim ary astrocytes were stim ulated w ith IL-1β to form active astrocytes to study the cross-talk between strom al cells(astrocytes)and TNBC cells in brain metastases.Our results showed that active astrocytes significantly increase the m alignancy of TNBC cells and prevent them from undergoing apoptosis caused by doxorubicin.We also found that the high level of IL-6 secreted by activated astrocytes was responsible for the drug resistance of breast cancer,which could be abolished by treatm ent of astrocytes with tam oxifen(TAM).The blockage of active astrocyte-derived IL-6 by a neutralizing antibody resulted in the attenuation of drug resistance,consequently enhancing the sensitivity of breast cancer cells to doxorubicin.Furthermore,the possible involved TAM-m odulated drug resistance mechanism may be associated with a decrease in IL-6 expression in astrocytes and the downregulation of MAPK and JAK2/STAT3 signaling in cancer cells.Our data suggested that TAMs might reduce drug resistance through the IL-6/JAK2/STAT3 signaling pathway,providing a possible therapy to treat brain metastasis in TNBCs,as estrogen receptor inhibitors(TAMs,etc.)can cross the blood-brain barrier. | Yongming Xu Yanrong Zhu Yong Yue Shaofeng Pu Junzhen Wu Yingying Lv Dongping Du | 2020 | Acta Biochimica et Biophysica Sinica2020，52，12： | 1 |
| 10 | Photonic drop splitters based on self-collimation ring resonators in a silicon photonic crystal显示文摘 | Junjun Li Xiyao Chen Zexuan Qiang Junzhen Jiang Guimin Lin Xiaofu Xu Hui Li Yishen Qiu | 2011 | Optics Communications2011，，24： | 1 |
| 11 | MicroRNA‐224 is upregulated in HepG2 cells and involved in cellular migration and invasion显示文摘 | QiongLi GeWang Jin‐LuShan Zhi‐XiangYang Hong‐ZhongWang JinFeng Ji‐JunZhen ChuanChen Zhi‐MinZhang WenXu Xi‐ZhongLuo DongWang | 2009 | Journal of Gastroenterology and Hepatology2009，，1： | 1 |
| 12 | Experiments of separating and fea- turing an efficient SRB 显示文摘 | Jiang Yanli Li Aihua Di Junzhen | 2012 | Applied Mechanics and Materials2012，170，173： | 1 |
| 13 | Effect of dynamic high-pressure microfluidization at different temperatures on the antigenic response of bovine β-lactoglobulin显示文摘 | Zhong Junzhen Liu Chengmei Liu Wei | 2011 | Eur Food Res Tech2011，233，1： | 1 |
| 14 | Suppressing trap states and energy loss by optimizing vertical phase distribution through ternary strategy in organic solar cells显示文摘Suppressing the trap-state density and the energy loss via ternary strategy was demonstrated.Favorable vertical phase distribution with donors(acceptors)accumulated(depleted)at the interface of active layer and charge extraction layer can be obtained by introducing appropriate amount of polymer acceptor N2200 into the systems of PBDB-T:IT-M and PBDB-TF:Y6.In addition,N2200 is gradiently distributed in the vertical direction in the ternary blend film.Various measurements were carried out to study the effects of N2200 on the binary systems.It was found that the optimized morphology especially in vertical direction can significantly decrease the trap state density of the binary blend films,which is beneficial for the charge transport and collection.All these features enable an obvious decrease in charge recombination in both PBDB-T:IT-M and PBDB-TF:Y6 based organic solar cells(OSCs),and power conversion efficiencies(PCEs)of 12.5%and 16.42%were obtained for the ternary OSCs,respectively.This work indicates that it is an effective method to suppress the trap state density and thus improve the device performance through ternary strategy. | Pengqing Bi Shaoqing Zhang Tong Xiao Minghuan Cui Zhihao Chen Junzhen Ren Chaochao Qin Guanghao Lu Xiaotao Hao Jianhui Hou | 2021 | Science China Chemistry2021，64，4： | 1 |
| 15 | The proparation of perovskite type strontium titanate by sol-gel process 显示文摘 | YAN XIURU WANG JUNZHEN WANG JIANPIN | 1995 | Transactions of Tianjin University1995，1，2： | 1 |
| 16 | Photo catalytic degradation of water-soluble does by CaCO3显示文摘 | Fu Xixian Yang Qiuhua Wang Junzhen | 2003 | Journal of Rare Earth2003，21，4： | 1 |
| 17 | The relationship between functional properties and aggregation changes of whey protein induced by high pressure microfluidization显示文摘 | LIU Chengmei ZHONG Junzhen LIU Wei | 2011 | Journal of Food Science2011，76，4： | 1 |
| 18 | Relationship between functional properties and aggregation changes of whey protein induced by high pressure mierofluidization显示文摘 | LIU Chengmei ZHONG Junzhen LIU Wei | 2011 | Journal of Food Science2011，76，4： | 1 |
| 19 | Antigenicity and functional properties offl-lactoglobulin conjugated with fructo- oligosaccharides in relation with conformational changes显示文摘 | ZHONG Junzhen XU Yujia LIU Wei | 2013 | Journal of Dairy Science2013，96，5： | 1 |
| 20 | Optimization of Preparation of Fe_(3)O_(4)-L by Chemical Co-Precipitation and Its Adsorption of Heavy Metal Ions显示文摘To address the serious pollution of heavy metals in AMD,the difficulty and the high cost of treatment,Fe_(3)O_(4)-L was prepared by the chemical co-precipitation method.Based on the single-factor and RSM,the effects of particle size,total Fe concentration,the molar ratio of Fe^(2+)to Fe^(3+)and water bath temperature on the removal of AMD by Fe_(3)O_(4)-L prepared by chemical co-precipitation method were analyzed.Static adsorption experiments were conducted on Cu^(2+),Zn^(2+)and Pb^(2+)using Fe_(3)O_(4)-L prepared under optimal conditions as adsorbents.The adsorption properties and mechanisms were analyzed by combining SEM-EDS,XRD and FTIR for characterization.The study showed that the effects of particle size,total Fe concentration and the molar ratio of Fe^(2+)to Fe^(3+)are larger.Obtained by response surface optimization analysis,the optimum conditions for the preparation of Fe_(3)O_(4)-L were a particle size of 250 mesh,a total Fe concentration of 0.5 mol/L,and a molar ratio of Fe^(2+)to Fe^(3+)of 1:2.Under these conditions,the removal rates of Cu^(2+),Zn^(2+),and Pb^(2+)were 94.52%,88.49%,and 96.69%respectively.The adsorption of Cu^(2+),Zn^(2+)and Pb^(2+)by Fe_(3)O_(4)-L prepared under optimal conditions reached equilibrium at 180 min,with removal rates of 99.99%,85.27%,and 97.48%,respectively.The adsorption reaction of Fe_(3)O_(4)-L for Cu^(2+)and Zn^(2+)is endothermic,while that for Pb^(2+)is exothermic.Fe_(3)O_(4)-L can still maintain a high adsorption capacity after five cycles of adsorption-desorption experiments.Cu^(2+),Zn^(2+)and Pb^(2+)mainly exist as CuFe_(2)O_(4),Zn(OH)2,ZnFe_(2)O_(4)and PbS after being adsorbed by Fe_(3)O_(4)-L,which is the result of the combination of physical diffusion,ion exchange and surface complexation reaction. | Junzhen Di Xueying Sun Siyi Zhang Yanrong Dong Bofu Yuan | 2023 | Journal of Renewable Materials2023，11，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员