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| 1 | Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality显示文摘AIM: To assess the additive effect of lubiprostone on the quality of colon preparation in diabetics given single-dosed polyethylene glycol electrolyte(PEG)for colonoscopy.METHODS:This was an investigator-initiated,singlecenter,single-blinded prospective trial comparing the efficacy of L+PEG to PEG alone on colon preparation quality in diabetics undergoing screening colonoscopy.The study was approved by our institution’s IRB.The PEG was given as a single-dose to address patientcompliance concerns voiced by our IRB with splitdosing.All patients received only clear liquids the day prior to colonoscopy.Experimental group(Grp L)received PEG+1 dose L 2 h prior to and 2 h after PEG completion.Control group(Grp C)received only PEG the evening prior to the colonoscopy.Patients were randomly assigned to one of the 2 groups.The endoscopist was blinded to which colon prep was given and all colonoscopies were complete.Upon colonoscopy completion,the endoscopist rated the colon prep-quality by a validated 5-point Likert scale(1-excellent to 5-inadequate).RESULTS:Sixty patients were enrolled in the study;30 Grp L and 30 Grp C.Overall,patients were excluded due to study non-completion in 12(41%)Grp L and 5(17%) Grp C,P=0.04.Average colon preparation score Grp L =2.47 and Grp C=3.00,P=0.09.Although this was not statistically significant,there was a trend towards improved colon prep in Grp L.Statistical significance may have been achieved if completion rates had been similar between both study groups.CONCLUSION:Use of 2-L capsules with PEG resulted in a trend towards improved colon prep over PEG alone in diabetic patients when given as a single-dose regimen. | Erika Grigg Moonkyung C Schubert Joshua Hall Fadi Rahhal Dimple Raina Subbaramiah Sridhar Sherman M Chamberlain | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，7： | 5 |
| 2 | Concurrent removal of intravitreal lens fragments after phacoemulsification with pars plana vitrectomy prevents development of retinal detachment显示文摘AIM: To evaluate the outcomes of 'concurrent vitrectomy' to retrieve dislocated lens fragment during phacoemulsification.METHODS: In a retrospective, observational case series, data of patients who underwent 'concurrent' pars plana vitrectomy(PPV) for dislocated lens fragments between the period 2000 and 2008 were reviewed. Data collected included patient demographics, pre-operative visual acuity, intra-operative occurrence of retinal breaks, duration of follow up, post-operative intraocular pressure, final best-corrected visual acuity(BCVA),presence of cystoid macular edema(CME) and occurrence of rhegmatogenous retinal detachment(RRD).· RESULTS: A total of 58 eyes of 58 patients were included in the study. At 12 mo the mean postoperative BCVA was log MAR 0.17(20/30) with a range of log MAR0 to 0.69(20/20 to 20/100), with 96.6%(56/58) of patients showing post- operative improvement in visual acuity(P =0.005). None of the patients developed postoperative retinal detachment, endophthalmitis or non-resolving uveitis at 12 mo.CONCLUSION: Our study results suggest concurrent PPV for retained lens fragments after cataract surgery is beneficial and may decrease the risk of glaucoma and prevent development of RRD. | Kakarla V Chalam Ravi K Murthy Joshua C Priluck Vijay Khetpal Shailesh K Gupta | 2015 | International Journal of Ophthalmology(English edition)2015，8，1： | 4 |
| 3 | 跨音速转子叶顶泄漏流/主流交界面的前移机制显示文摘采用数值计算和实验研究相结合的方法,研究了跨音速转子叶顶泄漏流与主流交界面轴向位置随流量的变化规律和机制。该跨音转子是美国圣母大学一级半跨音速压气机转子。研究发现机匣壁面脉线分布能够定性反映壁面轴向剪切应力分布,可用来识别叶顶泄漏流与主流的交界面位置。通过机匣壁面的脉线分布,可以看出机匣壁面存在两条零剪切应力线。第一条零剪切应力线表示来流与叶顶泄漏流之间交界面的时间和周向平均轴向位置,在小流量工况下交界面靠近顶部叶片的前缘。计算和实验结果都表明,随着质量流量的减小,叶顶泄漏流与主流交界面的轴向位置不断向叶片前缘移动。在近失速点,交界面到达叶片前缘,泄漏流即将溢出。泄漏流与主流的轴向动量比随流量减小不断增大的变化规律进一步说明,间隙区域泄漏流与主流的轴向动量平衡是导致交界面不断前移直至溢出的内在机制。 | 杜娟 林峰 陈静宜 Mark H Ross Joshua D Cameron Scott C Morris | 2011 | 工程热物理学报2011，32，6： | 3 |
| 4 | Computer applications for selecting operating parameters of stationary grain crop thresher显示文摘In this study,various operating parameters influencing performance of stationary grain crop threshers were established.These parameters were deduced from the established analytical models describing the underlying principles for the crop characteristics and machine variables as factors influencing the overall machine performance of a stationary multi-crop thresher.A computer programme written in Visual Basic was used to select optimum operating performance of the threshing process in a stationary tooth–peg grain crop thresher.An IITA-popularized stationary multi-crop thresher was used to test the practical feasibility of the computer based output of the threshing process.A split–split–unit statistical design was used for data collection.The data collected were analyzed using the GENSTAT 5 statistical package with its computer programme.The results showed that graphs of data from measured thresher performance indices against the predicted data for all the established models indicated high correlation between the models and the measured data at p≤5%significance level.The minimum energy requirements for detachment of sorghum and rice were observed at the threshing cylinder speed of 500 r/min(10.5 m/s)and 615 r/min(13.0 m/s),respectively.The combination of the threshing cylinder speed of 500 r/min(10.5 m/s)and 615 r/min(13.0 m/s)at crop moisture content of 12.8%and 16.2%indicated optimum threshing conditions for sorghum and rice,respectively. | Joshua Olanrewaju Olaoye Kayode C Oni Mary M Olaoye | 2010 | International Journal of Agricultural and Biological Engineering2010，3，3： | 3 |
| 5 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022，13，7： | 2 |
| 6 | Long-term in vivoimaging of experience dependent synaptic plasticity in adult cortex显示文摘 | Joshua T Brian C Graham K | 2002 | Nature2002，420，： | 1 |
| 7 | The chemistry and biotransformation of tea constitu- ents 显示文摘 | Sang S M Joshua D L Ho C T | 2011 | Pharmacological Research2011，64，： | 1 |
| 8 | Non-intrusive load shed verification显示文摘 | DAVID C B DONG J JOSHUA P J | 2007 | Power System2007，34，13： | 1 |
| 9 | The contribution of melanin to microbial pathogenesis显示文摘 | Joshua D Nosanchuk Arturo C | 2003 | Cellular Microbiology2003，5，4： | 1 |
| 10 | The conserved KMN network constitutes the core micmtubule-binding site of the kinetochore显示文摘 | IAIN M C JOSHUA S ELIZABETH M | 2006 | Cell2006，127，： | 1 |
| 11 | A global geometric framework for nonlinear dimensionality reduction 显示文摘 | Joshua B Tenenbaum V d S Langford J C | 2000 | Science2000，290，5500： | 1 |
| 12 | Loop-mediated isothermal amplification assay for rapid detection of common strains of Escherichia coli显示文摘 | Joshua H Shilpa B Ishwad C | 2008 | J Clin Microbiol2008，46，8： | 1 |
| 13 | A Global Geometric Framework for Nonlinear Dimesionality eduction 显示文摘 | Joshua B Tenenbaum Vin de Silva John C L | 2000 | Science2000，290，5500： | 1 |
| 14 | Strategy for combining heat treatment, cium infiltration, and biological control to reduce postharvest decay of' Gala' apple 显示文摘 | William S C Wojciech J J Joshua D K | 1999 | Hort Science1999，34，4： | 1 |
| 15 | Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes显示文摘 | Chen J Steven C H Joshua F A | 2004 | Pharm Res2004，21，11： | 1 |
| 16 | Henoch-Schonlein pur- pura with thrombocythaemia:an abnormality in Smad4 expression? 显示文摘 | Joshua M Brostoff-Gopinath M Ranganna C | 2009 | Rheumatol Int2009，29，5： | 1 |
| 17 | Control of green and red upconversion in NaYF4:Yb3+,Er3+ nanoparticles by excitation modulation显示文摘 | Gainer C F Joshua G S de Silva C R | | 0，，46： | 1 |
| 18 | Influence of prohexadione calcium on pod yield and pod loss of peanut显示文摘 | Joshua B B David L J Alan C Y | 2002 | Agronomy Journal2002，94，2： | 1 |
| 19 | Challenges for database management in the internet of things显示文摘 | Joshua C Anne J | 2009 | IETE Teehnical Review (Institution of Eleetronics and Telecommunication Engineers India)2009，26，5： | 1 |
| 20 | A global geomet- ric framework for nonlinear dimensionality reduction显示文摘 | Joshua B Tenenbaum Vin de Silva John C | 2000 | Sci- ence2000，290，22： | 1 |
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