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| 1 | HOS3, an ELO-Like Gene, Inhibits Effects of ABA and Implicates a S-1-P/Ceramide Control System for Abiotic Stress Responses in Arabidopsis thaliana显示文摘Arabidopsis thaliana 的 hyper-osmotically 敏感的异种,指明的 hos3-1 (渗透地应答的基因的高表示) ,基于它 RD29A 的超被识别: 在有 NaCl 和骆驼毛的织物的处理之上的 LUC 倡导者熔化植物。这些回答含有破坏基因作为 RD29A 压力应答的小径的一个直接或间接的否定管理者。由定序 T-DNA 边阶的 flanking 区域,破坏基因在地点 At4g36830,这被决定,作为与高相同编码通常认为的蛋白质到 CIG30 (ELO2/FEN1 ) 注解了。CIG30 在合成被含有很长锁住丰满的酸(VLCFA ) ,它是为 sphingolipids 和 ceramides 的必要先锋。改变了骆驼毛的织物超敏性特征的压力回答,包括减少的根生长抑制并且与骆驼毛的织物处理减少了萌芽并且从叶子减少了水损失,被突变而产生之遗传的 hos3-1 和 hos3-2 异种展出。hos3-2 异种部分在它的抄本丰富被压制并且作为一个后退的特点被继承。进一步,在 35SCaMV 倡导者的控制下面的 HOS3 ORF 象 RD29A 一样恢复了野类型的 NaCl 根和骆驼毛的织物根生长敏感: 在变异的植物的 LUC 光。我们也这里证明 HOS3 野类型的基因机能上地补充 elo2 和 elo3 酵母异种的敏感到 monensin。而且, hos3-1 和 hos3-2 等位基因分享了增加的敏感到除草剂 Metolachlor,它在 VLCFA 的合成禁止酰链延伸,并且 HOS3 机能上地补充了 elo2 和 elo3 并且恢复了 VLCFA 的层次。一起,这些数据证实 HOS3 禁止调停骆驼毛的织物的压力回答并且含有控制为不能生活的应力发信号和回答的几个方面指的 VLCFA 小径和产品。结果也在有气孔的行为的控制为 ceramide 的一个角色提供支持。 | Tanya M. Quist Irina Sokolchik Huazhong Shi Robert J. Joly Ray A. Bressan Albino Maggio Meena Narsimhan Xia Li | 2009 | Molecular Plant2009，2，1： | 7 |
| 2 | High-resolution multimodal flexible coherent Raman endoscope显示文摘Coherent Raman scattering microscopy is a fast,label-free,and chemically specific imaging technique that shows high potential for future in vivo optical histology.However,the imaging depth in tissues is limited to the sub-millimeter range because of absorption and scattering.Realization of coherent Raman imaging using a fiber endoscope system is a crucial step towards imaging deep inside living tissues and providing information that is inaccessible with current microscopy tools.Until now,the development of coherent Raman endoscopy has been hampered by several issues,mainly related to the fiber delivery of the excitation pulses and signal collection.Here,we present a flexible,compact,coherent Raman,and multimodal nonlinear endoscope(4.2mm outer diameter,71mm rigid length)based on a resonantly scanned hollow-core Kagomé-lattice double-clad fiber.The fiber design enables distortion-less,background-free delivery of femtosecond excitation pulses and back-collection of nonlinear signals through the same fiber.Sub-micrometer spatial resolution over a large field of view is obtained by combination of a miniature objective lens with a silica microsphere lens inserted into the fiber core.We demonstrate high-resolution,high-contrast coherent anti-Stokes Raman scattering,and second harmonic generation endoscopic imaging of biological tissues over a field of view of 320μm at a rate of 0.8 frames per second.These results pave the way for intraoperative label-free imaging applied to real-time histopathology diagnosis and surgery guidance. | Alberto Lombardini Vasyl Mytskaniuk Siddharth Sivankutty Esben Ravn Andresen Xueqin Chen Jérôme Wenger Marc Fabert Nicolas Joly Frédéric Louradour Alexandre Kudlinski Hervé Rigneault | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 3 | Multidisciplinary management of Mirizzi syndrome with cholecystobiliary fistula: the value of minimally invasive endoscopic surgery显示文摘Mirizzi syndrome, a rare complication of gallstones, is defined by obstruction of the main bile duct. This obstruction may worsen and thus result in cholecystobiliary fistula. Surgical management of Mirizzi syndrome is complicated by the presence of inflamed tissue around the hepatic pedicle, making it impossible to distinguish between the main bile duct and the gallbladder. The surgeon's first task is to perform subtotal cholecystotomy(from the fundus of the gallbladder to the neck) without trying to locate the cystic duct. In a second step, the gallstones are extracted and the main bile duct is then repaired. In most cases, a T-tube is used to drain the main bile duct, and abdominal drainage is left in place(in case a bile fistula forms). This study concluded that preoperative drainage of the main bile duct in the treatment of Mirizzi syndrome types II and III is feasible and might help to decrease the postoperative complication rate. | Fabien Le Roux Charles Sabbagh Brice Robert Thierry Yzet Laurent Dugue Jean-Paul Joly Jean-Marc Regimbeau | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，5： | 6 |
| 4 | Usefulness of Transjugular Intrahepatic Portosystemic Shunt in the Management of Bleeding Ectopic Varices in Cirrhotic Patients显示文摘 | V. Vidal L. Joly P. Perreault L. Bouchard M. Lafortune G. Pomier-Layrargues | 2006 | CardioVascular and Interventional Radiology2006，，2： | 2 |
| 5 | Refinery production scheduling toward Industry 4.0显示文摘Understanding the holistic relationship between refinery production scheduling(RPS) and the cyber-physical production environment with smart scheduling is a new question posed in the study of process systems engineering. Here, we discuss state-of-the-art RSPs in the crude-oil refining field and present examples that illustrate how smart scheduling can impact operations in the high-performing chemical process industry. We conclude that, more than any traditional off-the-shelf RPS solution available today, flexible and integrative specialized modeling platforms will be increasingly necessary to perform decentralized and collaborative optimizations,since they are the technological alternatives closer to the advanced manufacturing philosophy. | Marcel JOLY Darci ODLOAK Mario Y. MIYAKE Brenno C. MENEZES Jeffrey D. KELLY | 2018 | Frontiers of Engineering Management2018，5，2： | 2 |
| 6 | 无针头注射+皮内免疫--猪疫苗接种的一种完美组合方法显示文摘在养猪业中,接种疫苗是预防和控制多种病原体的首选方法。传统上,疫苗借助针头和注射器通过肌肉注射的方法进行接种。然而,鉴于注射方法对人类和动物健康的影响,由此激发了研究人员寻找替代性方法的研究。除了克服原有方法的缺点,替代方法的研制也是出于加强疗效的考虑,一些新方法的疗效与使用针头和注射器接种疫苗的方法一样甚至更为有效。本文介绍的这种方法结合了无针头注射和皮内接种疫苗各自的益处。 | 高凌云 潘雪男 韩浩月 Rika Jolie | 2016 | 国外畜牧学(猪与禽)2016，36，9： | 2 |
| 7 | LiToTac: An Interactive-Interface Software for Finite Element Analysis of Multiple Contact Dynamics显示文摘In order to investigate the mechanical behavior of systems with complex architecture and a large number of contacting bodies,a finite element software,named LiToTac,has been developed by using the object-oriented programming technique.This software,with an interactive graphical user interface,is able to handle highly non-linear problems including multiple contacts and large deformation.More importantly,the contact detection based on a hybrid three-stages methodology can be performed automatically,which is more efficient than the common strategies of pre-defining contact zones in commercial FEM software like ANSYS,ABAQUS,etc.In addition,the contact solver in LiToTac is portable between dynamic and quasi-static codes and can accurately solve contact coupled with friction in a reduced system.Several numerical examples are carried out to illustrate the functionality and capacity of the software package. | Lei Peng Zhiqiang Feng Pierre Joli Christine Renaud | 2019 | Computer Modeling in Engineering & Sciences2019，，1： | 2 |
| 8 | Global dispersal and diversification of the genus Schoenus (Cyperaceae) from the Western Australian biodiversity hotspot显示文摘The predominantly austral genus Schoenus L.is the largest genus in tribe Schoeneae and one of the ten most species-rich Cyperaceae genera,with over 150 accepted species found mostly in Australia,New Zealand,southeast Asia,and southern Africa.Here,we use data based on two nuclear and three plastid DNA regions to present one of the most comprehensive phylogenetic reconstructions of a genus in Cyperaceae to date,covering over 70%of described species of Schoenus.After recent taxonomic realignments in the last 4 years have both added and removed species from the genus,we show that Schoenus is now monophyletic.In addition,our results indicate that Schoenus originated in Western Australia in the Paleocene and eventually dispersed to surrounding continents,but rarely back.The diversification rate of the genus appears to have slightly decreased over time,and there has not been an increase associated with the establishment of the Cape clade endemic to the sclerophyllous fynbos vegetation type,such as has been reported in other plant lineages endemic to the Cape region.These results will serve as a template to understanding the complex patterns of genome size evolution and to untangle drivers of diversification in this genus. | Tammy L.Elliott Ruan van Mazijk Russell L.Barrett Jeremy J.Bruhl Simon Joly Ngalirendwe Muthaphuli Karen L.Wilson A.Muthama Muasya | 2021 | Journal of Systematics and Evolution2021，59，4： | 2 |
| 9 | 重新审视“基因歧视”:关于伦理、法律、社会问题的思考显示文摘自2003年起,'人类基因组计划'顺利破解人类遗传密码后,与基因相关的伦理、法律、社会问题的探讨也层出不穷。在这些问题中,尤为引人关注的就是'基因歧视'问题。'基因歧视'是指根据实际存在或者可能显现的遗传特征,对于个人或者其家人进行不公平对待或者对其身份进行基因分析的行为。学术界对'基因歧视'几十年的研究绝大多数都集中在就业和保险领域。面对基因技术的急速发展,消费者直接购买的基因检测产品的出现,国家将精准医疗列入'十三五'发展规划,表现在遗传学的发展等方面,都对'基因歧视'这一现象有着深远的影响,值得我们重新审视这个问题。本文结合基因科技发展的新方向及世界主要国家针对'基因歧视'的政策主张,对该问题从以下四个方面进行重新思考:对'基因歧视'在保险和就业领域进行分析、结合当前全球基因技术发展的新情况,介绍各国反基因歧视的立法现状、对中国当前应对'基因歧视'的政策规定进行分析及介绍随着基因科技的迅猛发展,对新型'基因歧视'问题进行分析。 | 宋凌巧 Yann Joly | 2018 | 科技与法律2018，0，4： | 2 |
| 10 | Sensitivity and specificity of clinical, histologic and immunologic features in the diagnosis of paraneoplastic pemphigus 显示文摘 | Joly P Richard C Gilbert D | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 11 | Content-based copy retrieval using distortion-based probabilistic similarity search 显示文摘 | Joly A Buisson O Frelicot C | 2007 | IEEE Trans on Multimedia2007，9，2： | 1 |
| 12 | Clinical impact and pathogenocity of Acinetobacter显示文摘 | Joly Guillon ML | 2005 | Clin Microbiol Infect2005，11，11： | 1 |
| 13 | The effect of storage and lag time on MS2 bacteriophage susceptibility to ultraviolet radiation 显示文摘 | Jolis D | 2002 | Water Environ Res2002，74，6： | 1 |
| 14 | Synthesis of 1-deoxymannojirimycin analogues using N-tosyl and N-nosyl activated aziridines derived {rom 1 amino 1-deoxyglucitol显示文摘 | Mao H Joly G J Peeters K | 2001 | Tetrahedron2001，57，： | 1 |
| 15 | Weak Convergence for the Stochastic Heat Equation Driven by Gaussian White Noise 显示文摘 | Bardina X Jolis M Quer-Sardanyons L | 2010 | Electronic Journal of Probability2010，15，39： | 1 |
| 16 | Chemical sensors based on amplifying fluorescent conjugated polymers显示文摘 | Thomas SW Ⅲ Joly GD Swager TM | | 0，，04： | 1 |
| 17 | Effects of microcystin-LR on development of medaka fish embryos ( Oryzias latipes )显示文摘 | Claire Jacquet Violette Thermes Amaury de Luze Simone Puiseux-Dao Cécile Bernard Jean-Stéphane Joly Franck Bourrat Marc Edery | 2003 | Toxicon2003，，2： | 1 |
| 18 | White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury显示文摘 | Fernando Malee S Simpson Jolie E Matthews Fiona | 2006 | Stroke2006，37，6： | 1 |
| 19 | Planning and scheduling models for refinery operations 显示文摘 | Pinto J M Joly M Moro L F L | 2000 | Computers & Chemical Engineering2000，24，910： | 1 |
| 20 | The proximal promoter region ofthe zebrafish gsdf gene is sufficient to mimic the spatio-temporalexpression pattern of the endogenous gene in Sertoli and granulosacells显示文摘 | Gautier A Sohm F Joly J S | 2011 | Biology of Reproduction2011，85，6： | 1 |
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