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| 1 | The Yellow Sea green tides were dominated by one species, Ulva (Enteromorpha) prolifera, from 2007 to 2011显示文摘Green tides have occurred in the Yellow Sea successively from 2007 to 2011. Genetic analysis of the 5-year green-tide-forming algae needs to be performed to determine the source of the biomass and understand the mechanism of the green tide blooms. In this study, free-floating green algae were collected at different sites in the Yellow Sea in 2010 and 2011. Data on 182 free-floating samples and 155 attached Ulva samples from previous studies on the Yellow Sea green tides from 2007 to 2009 were also taken into consideration. Morphology observation and molecular phylogenetic analyses indicated that the Yellow Sea green tides were dominated by a single species, Ulva prolifera, from 2007 to 2011. Considering that at least five Ulva species inhabit the north coast of China, the unialgal composition of the green tides implied that (1) there may be some special physiology and propagation pathways of U. prolifera for its rapid expansion, (2) the mechanisms of the Yellow Sea green tide formation were similar for the last five years, and (3) the intra-species genetic variation and population structure of U. prolifera need to be studied to determine the exact origin of the bloom-forming biomass. | ZHAO Jin JIANG Peng LIU ZhengYi WEI Wei LIN HanZhi LI FuChao WANG JinFeng QIN Song | 2013 | Chinese Science Bulletin2013,58,19: | 27 |
| 2 | Nanomaterials and bone regeneration显示文摘The worldwide incidence of bone disorders and conditions has been increasing. Bone is a nanomaterials composed of organic(mainly collagen) and inorganic(mainly nano-hydroxyapatite) components, with a hierarchical structure ranging from nanoscale to macroscale. In consideration of the serious limitation in traditional therapies, nanomaterials provide some new strategy in bone regeneration. Nanostructured scaffolds provide a closer structural support approximation to native bone architecture for the cells and regulate cell proliferation, differentiation, and migration, which results in the formation of functional tissues. In this article,we focused on reviewing the classification and design of nanostructured materials and nanocarrier materials for bone regeneration, their cell interaction properties, and their application in bone tissue engineering and regeneration. Furthermore, some new challenges about the future research on the application of nanomaterials for bone regeneration are described in the conclusion and perspectives part. | Tao Gong Jing Xie Jinfeng Liao Tao Zhang Shiyu Lin Yunfeng Lin | 2015 | Bone Research2015,3,3: | 23 |
| 3 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017,10,7: | 19 |
| 4 | Spatial patterns of ecosystem vulnerability changes during 2001–2011 in the three-river source region of the Qinghai-Tibetan Plateau, China显示文摘The three-river source region(TRSR, including Yangtze, Yellow and Lancang rivers), located in the Qinghai-Tibetan Plateau, China, is a typical alpine zone with apparent ecosystem vulnerability and sensitivity. In this paper, we introduced many interdisciplinary factors, such as landscape pattern indices(Shannon diversity index and Shannon evenness index) and extreme climate factors(number of extreme high temperature days, number of extreme low temperature days, and number of extreme precipitation days), to establish a new model for evaluating the spatial patterns of ecosystem vulnerability changes in the TRSR. The change intensity(CI) of ecosystem vulnerability was also analyzed. The results showed that the established evaluation model was effective and the ecosystem vulnerability in the whole study area was intensive. During the study period of 2001–2011, there was a slight degradation in the eco-environmental quality. The Yellow River source region had the best eco-environmental quality, while the Yangtze River source region had the worst one. In addition, the zones dominated by deserts were the most severely deteriorated areas and the eco-environmental quality of the zones occupied by evergreen coniferous forests showed a better change. Furthermore, the larger the change rates of the climate factors(accumulative temperature of ≥10°C and annual average precipitation) are, the more intensive the CI of ecosystem vulnerability is. This study would provide a scientific basis for the eco-environmental protection and restoration in the TRSR. | GUO Bing ZHOU Yi ZHU Jinfeng LIU Wenliang WANG Futao WANG Litao YAN Fuli WANG Feng YANG Guang LUO Wei JIANG Lin | 2016 | Journal of Arid Land2016,8,1: | 16 |
| 5 | The fabrication of biomimetic biphasic CAN-PAC hydrogel with a seamless interfacial layer applied in osteochondral defect repair显示文摘Cartilage tissue engineering based on biomimetic scaffolds has become a rapidly developing strategy for repairing cartilage defects. In this study, a biphasic CAN-PAC hydrogel for osteochondral defect(OCD)regeneration was fabricated based on the density difference between the two layers via a thermally reactive,rapid cross-linking method. The upper hydrogel was cross-linked by CSMA and NIPAm, and the lower hydrogel was composed of PECDA, AAm and PEGDA. The interface between the two layers was first grafted by the physical cross-linking of calcium gluconate and alginate, followed by the chemical cross-linking of the carbon-carbon double bonds in the other components. The pore sizes of the upper and lower hydrogels were ~ 187.4 and ~ 112.6 μm, respectively. The moduli of the upper and lower hydrogels were ~ 0.065 and~ 0.261 MPa. This prepared bilayer hydrogel exhibited the characteristics of mimetic composition, mimetic structure and mimetic stiffness, which provided a microenvironment for sustaining cell attachment and viability. Meanwhile, the biodegradability and biocompatibility of the CAN-PAC hydrogel were examined in vivo. Furthermore, an osteochondral defect model was developed in rabbits, and the bilayer hydrogels were implanted into the defect. The regenerated tissues in the bilayer hydrogel group exhibited new translucent cartilage and repaired subchondral bone, indicating that the hydrogel can enhance the repair of osteochondral defects. | Jinfeng Liao Taoran Tian Sirong Shi Xueping Xie Quanquan Ma Guo Li Yunfeng Lin | 2017 | Bone Research2017,5,2: | 10 |
| 6 | Zebrafish model for assessing induced organ toxicity by Strychnos nux-vomica显示文摘OBJECTIVE:To assess the acute organ toxicity of Strychnos nux-vomica with zebrafish model visually.METHODS:To assess acute toxicity,we initially determined the lethal concentration after Strychnos nux-vomica treatment for 24 h.Zebrafish was treated with five concentrations Strychnos nux-≦vo LC10 for 24 h,and the effects ofmica on morphology,function of heart,central nervous system,liver,kidney and organ-specific cell death were assessed.Next,we assessed the reversibility of toxic effect.RESULTS:Strychnos nux-vomica has an effect on the different organs of zebrafish,including heart,central nervous system,liver,and kidney,and cadiotoxicity induced by Strychnos nux-vomica was reversible to some extent.CONCLUSION:Zebrafish model is suitable for confirming the toxic target organs for Chinese traditional medicine. | Zhao Chongjun Tian Jinghuan Wang Jinfeng Feng Yaru Ni Yuanyuan Fan Jiaojiao Wang Chunmei Cao Dan Zou Qinwen Ma Zhiqiang Lin Ruichao | 2016 | Journal of Traditional Chinese Medicine2016,36,4: | 9 |
| 7 | Carbon Capture and Storage:History and the Road Ahead显示文摘The large-scale deployment of carbon capture and storage(CCS)is becoming increasingly urgent in the global path toward net zero emissions;however,global CCS deployment is significantly lagging behind its expected contribution to greenhouse gas emission reduction.Reviewing and learning from the examples and history of successful CCS practices in advanced countries will help other countries,including China,to promote and deploy CCS projects using scientific methods.This paper shows that the establishment of major science and technology CCS infrastructures in advanced countries has become the main source of CCS technological innovation,cost reduction,risk reduction,commercial promotion,and talent training in the development and demonstration of key CCS technologies.Sound development of CCS requires a transition from pilot-scale science and technology infrastructures to large-scale commercial infrastructures,in addition to incentive policies;otherwise,it will be difficult to overcome the technical barriers between small-scale demonstrations and the implementation of million-tonne-scale CCS and ten-million-tonne-scale CCS hubs.Geological CO_(2) storage is the ultimate goal of CCS projects and the driving force of CO_(2) capture.Further improving the accuracy of technologies for the measurement,monitoring,and verification(MMV)of CO_(2) storage capacity,emission reduction,and safety remains a problem for geological storage.CO_(2) storage in saline aquifers can better couple multiple carbon emission sources and is currently a priority direction for development.Reducing the energy consumption of lowconcentration CO_(2) capture and the depletion of chemical absorbents and improving the operational efficiency and stability of post-combustion CO_(2) capture systems have become the key constraints to largescale CCS deployment.Enhanced oil recovery(EOR)is also important in order for countries to maximize fossil fuel extraction instead of importing oil from less environmentally friendly oil-producing countries. | Jinfeng Ma Lin Li Haofan Wang Yi Du Junjie Ma Xiaoli Zhang Zhenliang Wang | 2022 | Engineering2022,8,7: | 9 |
| 8 | LICOM Model Datasets for the CMIP6 Ocean Model Intercomparison Project显示文摘The datasets of two Ocean Model Intercomparison Project(OMIP)simulation experiments from the LASG/IAP Climate Ocean Model,version 3(LICOM3),forced by two different sets of atmospheric surface data,are described in this paper.The experiment forced by CORE-II(Co-ordinated Ocean–Ice Reference Experiments,Phase II)data(1948–2009)is called OMIP1,and that forced by JRA55-do(surface dataset for driving ocean–sea-ice models based on Japanese 55-year atmospheric reanalysis)data(1958–2018)is called OMIP2.First,the improvement of LICOM from CMIP5 to CMIP6 and the configurations of the two experiments are described.Second,the basic performances of the two experiments are validated using the climatological-mean and interannual time scales from observation.We find that the mean states,interannual variabilities,and long-term linear trends can be reproduced well by the two experiments.The differences between the two datasets are also discussed.Finally,the usage of these data is described.These datasets are helpful toward understanding the origin system bias of the fully coupled model. | Pengfei LIN Zhipeng YU Hailong LIU Yongqiang YU Yiwen LI Jirong JIANG Wei XUE Kangjun CHEN Qian YANG Bowen ZHAO Jilin WEI Mengrong DING Zhikuo SUN Yaqi WANG Yao MENG Weipeng ZHENG Jinfeng MA | 2020 | Advances in Atmospheric Sciences2020,37,3: | 9 |
| 9 | Thermal Transfer During the Activation Process in LiSi/FeS2 Thermal Batteries显示文摘 | KANG Bo ZHANG Wenli LIN Haibo XING Yonghui ZHAO Jinfeng WANG Yan | 2016 | Chemical Research in Chinese Universities2016,32,4: | 6 |
| 10 | Morphological variability and genetic diversity in five species of Skeletonema(Bacillariophyta)显示文摘从中国沿海的水的 Skeletonema 的 12 紧张和来自朝鲜的西方海的另一紧张用轻显微镜学(LM ) 被检验,扫描并且传播电子显微镜学(SEM, TEM ) ,并且小子单元(SSU ) rDNA 顺序分析。我们识别了 Skeletonema 的四种:S。marinoi Sarno 和 Zingone, S。subsalsum (A.Cleve ) Bethge, S。dohrnii Sarno 和 Kooistra, S。回归线嗯 Cleve,以及象 Skeletonema 一样种。这些是 S 的第一个记录。marinoi, S。dohrnii 和 S。在中国的 subsalsum。象 Skeletonema 一样种类, MMDL5067,从 Changjiang 河的河口被孤立。这种的词法、种系发生的特征不任何以前出版的 Skeletonema 种类对应于那些。闰的 fultoportula 过程(IFPP ) 有长开的试管,和闰的 rimoportula 过程(IRP ) 在 IFPP 的边界内短、定位。种系发生的分析揭示了与 S 聚类的那 MMDL5630。回归线嗯在 NJ 和 MP,树,而是它的 IRP S 的以前描述的标本不同于那些。回归线嗯。IRP 部分是开的,与在试管的底的一个伸长的洞,并且比 IFPP 长。S 的一些标本。marinoi 和 S。dohrnii 也比 IFPP 有更长管状的 IRP。比作 S 的以前描述的标本。marinoi 和 S。dohrnii,我们识别了的这二个标本有更短的 IRP。我们的结果反映 Skeletonema 分类的歧义和差异。他们为未来鉴定和 Skeletonema 在中国附近在海引起的红潮的管理也是重要的。 | Jinfeng Cheng Yang Li Junrong Liang Yahui Gao PengWang Ho Kin-Chung Xin Lin | 2008 | Progress in Natural Science:Materials International2008,18,11: | 5 |
| 11 | Plasmonic resonance-linewidth shrinkage to boost biosensing显示文摘Coupling effects of surface plasmon resonance(SPR)induce changes in the wavelength,intensity,and linewidth of plasmonic modes.Here,inspired by coupling effects,we reveal an abrupt linewidth-shrinking effect in 2 D gold nanohole arrays at the azimuthal angle of 45°arising from the interference of two degenerate SPR modes.We further demonstrate the biosensing capability under various excitation conditions for detecting the critical molecular biomarker of prostatic carcinoma,and achieve the maximum sensitivity at this angle.Our study not only enhances the understanding toward plasmonic resonance-linewidth shrinking,but also provides a promising strategy to greatly improve biosensing performance by light manipulation on plasmonic nanostructures. | Min Gao Weimin Yang Zhengying Wang Shaowei Lin Jinfeng Zhu Zhilin Yang | 2020 | Photonics Research2020,8,7: | 4 |
| 12 | Breast-conserving therapy and modified radical mastectomy for primary breast carcinoma:a matched comparative study显示文摘Background:To compare two types of therapy for primary breast carcinoma,breast-conserving therapy(BCT) and modified radical mastectomy(MRM),in a matched cohort study.Methods:A series of 1,746 patients with primary breast cancer treated with BCT or MRM in a single Chinese institute between January 2000 and February 2009 were analyzed retrospectively to compare their outcomes with respect to the incidence of local recurrence(LR),distant metastasis,and survival.The patients were matched with regard to age at diagnosis,spreading to axillary lymph nodes,hormone receptor status,the use of neoadjuvant chemotherapy and maximal tumor diameter.The match ratio was 1:1,and each arm included 873 patients.Results:The median follow-up period was 71 months.The 6-year disease-free survival(DFS) and 6-year distant disease-free survival(DDFS) rates differed significantly between two groups.The 6-year local recurrence-free survival(LRFS) rates were 98.2% [95% confidence interval(CI):0.973-0.989] in the BCT group and 98.7%(95% CI:0.980-0.994) in the MRM group(P=0.182),respectively.DFS rates in BCT and MRM groups were 91.3%(95% CI:0.894-0.932) and 86.3%(95% CI:0.840-0.886)(P<0.001),respectively,whereas the DDFS rates in BCT and MRM groups were 93.6%(95% CI:0.922-0.950) and 87.7%(95% CI:0.854-0.900)(P<0.001),respectively.Conclusions:BCT in eligible patients is as effective as MRM with respect to local tumor control,DFS and DDFS,and may result in a better outcome than MRM in Chinese primary breast cancer patients. | Lize Wang Tao Ouyang Tianfeng Wang Yuntao Xie Zhaoqing Fan Benyao Lin Jinfeng Li | 2015 | Chinese Journal of Cancer Research2015,27,6: | 3 |
| 13 | Association between HER2 status and response to neoadjuvant anthracycline followed by paclitaxel plus carboplatin chemotherapy without trastuzumab in breast cancer显示文摘Background:We recently showed HER2-positive breast cancers are less likely to respond to neoadjuvant anthracycline chemotherapy.Here,we investigated whether HER2-positive breast cancers responded to sequential neoadjuvant anthracycline followed by paclitaxel plus carboplatin regimen in the absence of trastuzumab.Methods:Women(n=372) with operable primary breast cancer initially received two cycles of neoadjuvant anthracyclines,the clinical tumor response was assessed,then patients were received four cycles of paclitaxel plus carboplatin regimen.All the patients did not received trastuzumab treatment in the neoadjuvant setting.HER2 status was determined by immunohistochemistry and/or by fluorescence in situ hybridization in corebiopsy breast cancer tissue obtained before the neoadjuvant chemotherapy.Results:Eighteen percent(67/372) of patients achieved a pathologic complete response(p CR) in their breast.HER2-positive tumors had a significant higher p CR rate than HER2-negative tumors(33.0% versus 13.5%,P<0.001) in this cohort of 372 patients,and positive HER2 status remained an independent favorable predictor of p CR in a multivariate analysis [odds ratio(OR),2.26;95% confidence interval(CI),1.18 to 4.36,P=0.015].Furthermore,patients who responded to initial anthracycline regimens were more likely to respond to paclitaxel plus carboplatin than patients who did not(p CR,27.2% versus 14.6%,P=0.005).Patients with HER2-positive tumors exhibited a significant higher p CR rate than did patients with HER2-negative tumors in both anthracycline response group(40.5% versus 20.0%,P=0.025) and anthracycline non-response group(28.3% versus 11.3%,P=0.002).Conclusions:Under the circumstance of no trastuzumab treatment,women with HER2-positive cancers derive a large benefit from paclitaxel-carboplatin-based neoadjuvant chemotherapy. | Lu Yao Juan Zhang Yiqiang Liu Tao Ouyang Jinfeng Li Tianfeng Wang Zhaoqing Fan Tie Fan Benyao Lin Yuntao Xie | 2015 | Chinese Journal of Cancer Research2015,27,6: | 3 |
| 14 | Combinational biosynthesis and characterization of a fluorescent 82β-phycocyanin of Spirulina platensis显示文摘To biosynthesize fluorescent Spirulina platensis (Sp)β -phycocyanin (PC) in Escherichia coli, a BLASTP search for homologs of the cpeS gene, a chromophore lyase, was performed against the Synechocystis sp. PCC 6803 (S6) proteome. A highly homologous gene, slr2049, was obtained from the S6 genome. Sites 82 and 153 in -phycocyanin of Sp were modified by site-directed muta- genesis. Two recombinant expression vectors were constructed and transformed into E. coli BL21: (i) pCDF-cpcB (C153A)- slr2049-sll0583-ho1-pcyA; and (ii) pCDF-cpcB (C82I)-slr2049-sll0583-ho1-pcyA. Lyases encoded by the genes slr2049 and sll0583 catalyzed the linking of Sp 82β -PC to phycocyanobilin (PCB), and fluorescent CpcB (C153A)-PCB was generated. We present a strategy for the co-expression of multiple genes in a single expression vector to identify the function of an unknown gene. Recombinant phycobiliproteins produced on a large scale are promising fluorescent tags for diagnostics and pharmacology. | GUAN XiangYu ZHANG WeiJie CHI XiaoYuan LIN HanZhi WANG JinFeng QIN Song | 2012 | Chinese Science Bulletin2012,57,25: | 3 |
| 15 | A preliminary analysis on lithospheric thickness and crustal ages in central basin of South China Sea显示文摘The models about lithospheric thickness and thermal conduction inside the lithosphere and the top layer ofthe asthenosphere have been proposed in this study for four type regions: the midoceanic ridge, the extinct spreading ridge, the lithospheric fault fissure and the mouth of the extinct submarine volcanoes which are in deep sea bottom. The solutions of the models are found to be the same. The formulas of temperature distribution inside the lithosphere and the top layer of the asthenosphere, the lithospheric thicknesses to the heat flow and the crustal ages to the heat flow are obtained. The crustal ages and the lithospheric thicknesses of the central basin are calculated. And they are used to draw the lithospheric thicknesses and crustal ages maps of the central basin (in this paper both the central basin and the basin are the central basin of the South China Sea). According to their characteristics, the central basin is divided into three regions. The lithospheric thicknesses, crustal ages and heat flow distribution characteristics are discussed respectively. The formation and evolution of the South China Sea are analysed and it is thought that the South China Sea has undergone three episode-seafloor spreadings. | Chen Xue and Lin Jinfeng South China Sea Institute of Oceanology, the Chinese Academy of Sciences, Guangzhou 510301, China | 1997 | Acta Oceanologica Sinica1997,16,1: | 3 |
| 16 | Value of pre-treatment biomarkers in prediction of response to neoadjuvant endocrine therapy for hormone receptor-positive postmenopausal breast cancer显示文摘Objective: To determine the predictive ability of biomarkers for responses to neoadjuvant endocrine therapy (NET) in postmenopausal breast cancer. Methods: Consecutive 160 postmenopausal women with T 1-3 N 0-1 M 0 hormone receptor (HR)-positive invasive breast cancer were treated with anastrozole for 16 weeks before surgery. New slides of tumor specimens taken before and after treatment were conducted centrally for biomarker analysis and classified using the Applied Imaging Ariol MB-8 system. The pathological response was evaluated using the Miller & Payne classification. The cell cycle response was classified according to the change in the Ki67 index after treatment. Multivariable logistic regression analysis was used to calculate the combined index of the biomarkers. Receiver operating characteristic (ROC) curves were used to determine whether parameters may predict response. Results: The correlation between the pathological and cell cycle responses was low (Spearman correlation coefficient =0.241, P<0.001; Kappa value =0.119, P=0.032). The cell cycle response was significantly associated with pre-treatment estrogen receptor (ER) status (P=0.001), progesterone receptor (PgR) status (P<0.001), human epidermal growth factor receptor 2 (Her-2) status (P=0.050) and the Ki67 index (P<0.001), but the pathological response was not correlated with these factors. Pre-treatment ER levels [area under the curve (AUC) =0.634, 95% confidence interval (95% CI), 0.534-0.735, P=0.008] and combined index of pre-treatment ER and PgR levels (AUC =0.684, 95% CI, 0.591-0.776, P<0.001) could not predict the cell cycle response, but combined index including per-treatment ER/PR/Her-2/Ki67 expression levels could (AUC =0.830, 95% CI, 0.759-0.902, P<0.001). Conclusions: The combined use of pre-treatment ER/PgR/Her-2/Ki67 expression levels, instead of HR expression levels, may predict the cell cycle response to NET. | Min Ying Yingjian He Meng Qi Bin Dong Aiping Lu Jinfeng Li Yuntao Xie Tianfeng Wang Benyao Lin Tao Ouyang | 2013 | Chinese Journal of Cancer Research2013,25,4: | 2 |
| 17 | Development and Validation of a Nomogram for Prediction of the Risk of MAFLD in an Overweight and Obese Population显示文摘Background and Aims:Metabolic associated fatty liver disease(MAFLD)is a serious condition,and a simple meth-od is needed for practitioners to identify patients with the disease and have a high risk of disease progression.Meth-ods:We developed and validated a nomogram for fatty liver disease and reclassified the risk factors for MAFLD.The development cohort had 335 patients who received bioel-ectrical impedance analysis and liver ultrasound attenua-tion measurements at Shenzhen People’s Hospital between September 2020 and June 2021.The validation cohort had 200 patients from other hospitals who received the same evaluation.A random forest procedure and binary logistic analysis were used to screen for risk factors,establish a fatty liver disease predictive model,and forecast the risk of MAFLD.The performance of the nomogram was evaluated by measurement of discrimination,calibration,and clinical usefulness.Results:The nomogram provided good predic-tions in a model that included body mass index(BMI)and waist circumference.The areas under the curve of the nom-ogram were 0.793 in the development cohort and 0.774 in the validation cohort.The nomogram performed well for calibration,category-free net reclassification improvement,and integrated discrimination improvement.Decision curve analysis indicated the nomogram performed better than BMI for predicting net outcome.Conclusions:The nomo-gram was an effective screening tool for fatty liver disease,and for those overweight individuals,may help physicians make appropriate decisions regarding treatment of MAFLD. | Di Song Qian Ge Ming Chen Song Bai Xiaoshu Lai Gege Huang Mengmeng Liu Miaofang Lin Jinfeng Xu Fajin Dong | 2022 | Journal of Clinical and Translational Hepatology2022,10,6: | 1 |
| 18 | Matching energy of unicyclic and bicyclic graphs with a given diameter 显示文摘 | Chen Lin Liu Jinfeng Shi Yongtan$ | 2014 | Complexity2014,20,2: | 1 |
| 19 | Enhanced ferro-/piezoelectric properties of tape-casting-derived Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3) optoelectronic thick films显示文摘Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3)(xEr-BCTZ,x=0,0.005,0.01,0.015)multifunctional thick films were prepared by the tape-casting method,using sol-gel-derived nano-sized powders as the matrix material.The surface morphologies,photoluminescence,and electrical properties were investigated.Dense microstructures with pure perovskite structure were obtained in the thick films.By doping an appropriate amount of Er^(3+),the samples exhibit superior up-conversion photoluminescence performance and simultaneously enhanced electrical performances.In addition,relatively higher texture fractions(with the largest value of 83.5%)were realized through introducing plate-like BaTiO_(3) templates to make the thick film grow by the[001]_(c) orientation.And the ferro-/piezoelectric properties of the thick films were further improved,showing potential in the applications of micro-optoelectronic devices. | Jie XU Qiling LU Jinfeng LIN Cong LIN Xinghua ZHENG Tengfei LIN Xiao WU | 2020 | Journal of Advanced Ceramics2020,9,6: | 1 |
| 20 | Eddy-resolving Simulation of CAS-LICOM3 for Phase 2 of the Ocean Model Intercomparison Project显示文摘A 61-year(1958–2018)global eddy-resolving dataset for phase 2 of the Ocean Model Intercomparison Project has been produced by the version 3 of Chinese Academy of Science,the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics/Institute of Atmospheric Physics(LASG/IAP)Climate system Ocean Model(CAS-LICOM3).The monthly and a part of the surface daily data in this study can be accessed on the Earth System Grid Federation(ESGF)node.Besides the details of the model and experiments,the evolutions and spatial patterns of large-scale and mesoscale features are also presented.The mesoscale features are reproduced well in the high-resolution simulation,as the mesoscale activities can contribute up to 50%of the total SST variability in eddy-rich regions.Also,the large-scale circulations are remarkably improved compared with the low-resolution simulation,such as the climatological annual mean SST(the RMSE is reduced from 0.59°C to 0.47°C,globally)and the evolution of Atlantic Meridional Overturning Circulation.The preliminary evaluation also indicates that there are systematic biases in the salinity,the separation location of the western boundary currents,and the magnitude of eddy kinetic energy.All these biases are worthy of further investigation. | Yiwen LI Hailong LIU Mengrong DING Pengfei LIN Zipeng YU Yongqiang YU Yao MENG Yunlong LI Xiaodong JIAN Jinrong JIANG Kangjun CHEN Qian YANG Yaqi WANG Bowen ZHAO Jilin WEI Jinfeng MA Weipeng ZHENG and Pengfei WANG | 2020 | Advances in Atmospheric Sciences2020,37,10: | 1 |