|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ultrafast epitaxial growth of metre-sized single-crystal graphene on industrial Cu foil显示文摘A foundation of the modern technology that uses single-crystal silicon has been the growth of highquality single-crystal Si ingots with diameters up to 12 inches or larger. For many applications of graphene, large-area high-quality(ideally of single-crystal) material will be enabling. Since the first growth on copper foil a decade ago, inch-sized single-crystal graphene has been achieved. We present here the growth, in 20 min, of a graphene film of(5 ×50) cm^2 dimension with >99% ultra-highly oriented grains.This growth was achieved by:(1) synthesis of metre-sized single-crystal Cu(1 1 1) foil as substrate;(2)epitaxial growth of graphene islands on the Cu(1 1 1) surface;(3) seamless merging of such graphene islands into a graphene film with high single crystallinity and(4) the ultrafast growth of graphene film.These achievements were realized by a temperature-gradient-driven annealing technique to produce single-crystal Cu(1 1 1) from industrial polycrystalline Cu foil and the marvellous effects of a continuous oxygen supply from an adjacent oxide. The as-synthesized graphene film, with very few misoriented grains(if any), has a mobility up to ~23,000 cm^2 V^(-1)s^(-1)at 4 K and room temperature sheet resistance of ~230 Ω/□. It is very likely that this approach can be scaled up to achieve exceptionally large and high-quality graphene films with single crystallinity, and thus realize various industrial-level applications at a low cost. | Xiaozhi Xu Zhihong Zhang Jichen Dong Ding Yi Jingjing Niu Muhong Wu Li Lin Rongkang Yin Mingqiang Li Jingyuan Zhou Shaoxin Wang Junliang Sun Xiaojie Duan Peng Gao Ying Jiang Xiaosong Wu Hailin Peng Rodney S. Ruoff Zhongfan Liu Dapeng Yu Enge Wang Feng Ding Kaihui Liu | 2017 | Science Bulletin2017，62，15： | 40 |
| 2 | The Value of CT Attenuation in Distinguishing Atypical Adenomatous Hyperplasia from Adenocarcinoma in Situ显示文摘Background and objective:Advances in high-resolution computed tomography(CT)scanning have increased the detection of small ground-glass opacity(GGO)nodules and also allowed such images to be investigated in detail.However,it is difficult to differentiate atypical adenomatous hyperplasia(AAH)from adenocarcinoma in situ(AIS)with CT,even at follow-up,because they share many similar CT manifestations.While AAH is thought to be a precursor or even an early-stage lesion of lung adenocarcinoma,and the stepwise progression from AAH to AIS is thought to be reasonable.Therefore,the hypothesis that the attenuation of GGO is increased gradually from AAH to AIS is proposed.The aim of this study was to distinguish AAH from AIS with CT attenuation in patients with pure GGO nodules.Methods:Between January 2010 and December 2012,the CT findings in terms of the greatest diameter and mean CT attenuation(HU)were reviewed and correlated with pathology in 56 patients with AAH(n=21) and non-mucinous AIS(n=38) by two independent observers.All the 59 lesions were pure GGO nodules with size of 2 cm or smaller.To determine variability of measuring CT attenuation,we calculated the 95% confidence interval(CI)for the limits of agreement by using Bland-Altman analysis.Student t test was used to compare AAH and AIS in terms of diameter and CT attenuation.And receiver operating characteristic(ROC)curve was used to determine the optimal cut-off value of mean CT attenuation for differentiating AAH from AIS and obtain the diagnostic value.Two-tailed P value of less than 0.05 was considered to be significant.Results:For the manually measured CT attenuation,the 95% CI for the limits of agreement was-40 HU,50 HU for inter-observer variability.Although there was significant difference in nodule diameter between AAH and AIS(P=0.046),the overlap was considerable.The mean CT attenuation was (-718±53) HU(95%CI:-822,-604) for AAH,which was significantly smaller than(-600±35) HU(95%CI:-669,-531) for AIS(P=0.013).The area under curve(AUC)from ROC was 0.903 for differentiating AAH from AIS,and the cut-off value of-632 HU was optimal for differentiation between AAH and AIS,with sensitivity of 0.79,specificity of 0.95,and accuracy of 0.85.Conclusion:The mean CT attenuation can help the radiological differentiation between AAH and AIS. | Binghu JIANG Jichen WANG PengJIA Meizhao LE | 2013 | 中国肺癌杂志2013，16，11： | 34 |
| 3 | Development of real-time laser-scanning system to detect tree canopy characteristics for variable-rate pesticide application显示文摘Improving pesticide application efficiency is increasingly important in orchard spraying.In this study,a laser-scanning system was designed to acquire gridding volumes of a tree to quantify the geometry characteristics of the tree canopy in real-time.A laser-scanning sensor mounted on a linear guide was utilized to measure the structure of a target tree canopy.A computer was used to receive measurement data from the laser scanner and obtain the movement distance of the laser-scanning sensor from a controller.An algorithm written with VC#program was designed to calculate gridding volumes of trees by recognizing valid measurement data from the laser scanner.Laboratory evaluations were conducted on three kinds of regular objects,and the maximum relative errors of section volumes of the cuboid,triangular prism and cylinder objects were 3.3%,7.9%and 9.4%,respectively,which illustrated that the algorithm could calculate the section volumes in different parts of the objects with high accuracy.A conifer tree and an apple tree were chosen to verify detecting accuracy of the laser-scanning system at variable speeds and grid sizes.The variation coefficients of total volumes for each kind of the tree were 0.078 and 0.041,respectively,which indicated that the laser-scanning system could be applied to provide the gridding volumes of different canopy densities in real-time with good reliability for guiding a variable-rate sprayer. | Cai Jichen Wang Xiu Song Jian Wang Songlin Yang Shuo Zhao Chunjiang | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 14 |
| 4 | The levels, sources and reactivity of volatile organic compounds in a typical urban area of Northeast China显示文摘Air concentrations of volatile organic compounds(VOCs) were continually measured at a monitoring site in Shenyang from 20 August to 16 September 2017. The average concentrations of alkanes, alkenes, aromatics and carbonyls were 28.54, 6.30, 5.59 and9.78 ppbv, respectively. Seven sources were identified by the Positive Matrix Factorization model based on the measurement data of VOCs and CO. Vehicle exhaust contributed the most(36.15%) to the total propene-equivalent concentration of the measured VOCs,followed by combustion emission(16.92%), vegetation emission and secondary formation(14.33%), solvent usage(10.59%), petrochemical industry emission(9.89%), petrol evaporation(6.28%), and liquefied petroleum gas(LPG) usage(5.84%). Vehicle exhaust, solvent usage and combustion emission were found to be the top three VOC sources for O_3 formation potential, accounting for 34.52%, 16.55% and 11.94%, respectively. The diurnal variation of the total VOCs from each source could be well explained by their emission characteristics,e.g., the two peaks of VOC concentrations from LPG usage were in line with the cooking times for breakfast and lunch. Wind rose plots of the VOCs from each source could reveal the possible distribution of the sources around the monitoring site. The O_3 pollution episodes during the measurement period were found to be coincident with the elevation of VOCs, which was mainly due to the air parcel from the southeast direction where petrochemical industry emission was found to be dominant, suggesting that the petrochemical industry emission from the southeast was probably a significant cause of O_3 pollution in Shenyang. | Zhuobiao Ma Chengtang Liu Chenglong Zhang Pengfei Liu Can Ye Chaoyang Xue Di Zhao Jichen Sun Yiming Du Fahe Chai Yujing Mu | 2019 | Journal of Environmental Sciences2019，31，5： | 12 |
| 5 | Research on fiber optic gyro signal de-noising based on wavelet packet soft-threshold显示文摘Gyro's drift is not only the main drift error which influences gyro's precision but also the primary factor that affects gyro's reliability.Reducing zero drift and random drift is a key problem to the output of a gyro signal.A three-layer de-nosing threshold algorithm is proposed based on the wavelet decomposition to dispose the signal which is collected from a running fiber optic gyro(FOG).The coefficients are obtained from the three-layer wavelet packet decomposition.By setting the high frequency part which is greater than wavelet packet threshold as zero,then reconstructing the nodes which have been filtered out noise and interruption,the soft threshold function is constructed by the coefficients of the third nodes.Compared wavelet packet de-noise with forced de-noising method, the proposed method is more effective.Simulation results show that the random drift compensation is enhanced by 13.1%,and reduces zero drift by 0.052 6°/h. | Qian Huaming & Ma Jichen Coll.of Automation,Harbin Engineering Univ.,Harbin 150001,P.R.China | 2009 | Journal of Systems Engineering and Electronics2009，20，3： | 7 |
| 6 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 7 | Temperature Dependence of Ultrasonic Longitudinal Guided Wave Propagation in Long Range Steel Strands显示文摘Ultrasonic guided wave inspection is an effective non-destructive testing method which can be used for stress level evaluation in steel strands.Unfortunately the propagation velocity of ultrasonic guided waves changes due to temperature shift making the prestress measurement of steel strands inaccurate and even sometimes impossible.In the course of solving the problem,this paper reports on quantitative research on the temperature dependence of ultrasonic longitudinal guided wave propagation in long range steel strands.In order to achieve the generation and reception of a chosen longitudinal mode in a steel strand with a helical shaped surface,a new type of magnetostrictive transducer was developed,characterized by a group of thin clips and three identical permanent magnets.Excitation and reception of ultrasonic guided waves in a steel strand were performed experimentally.Experimental results shows that in the temperature range from-4 ℃ to 34 ℃,the propagation velocity of the L(0,1) mode at 160 kHz linearly decreased with increasing temperature and its temperature dependent coefficient was 0.90(m·s-1 ·(℃)-1) which is very close to the theoretical prediction.The effect of dimension deviation between the helical and center wires and the effect of the thermal expansion of the steel strand on ultrasonic longitudinal guided wave propagation were also analyzed.It was found that these effects could be ignored compared with the change in the material mechanical properties of the steel strands due to temperature shift.It was also observed that the longitudinal guided wave mode was somewhat more sensitive to temperature changes compared with conventional ultrasonic waves theoretically.Therefore,it is considered that the temperature effect on ultrasonic longitudinal guided wave propagation in order to improve the accuracy of stress measurement in prestressed steel strands.Quantitative research on the temperature dependence of ultrasonic guided wave propagation in steel strands provides an important basis for the compensation of temperature effects in stress measurement in steel strands by using ultrasonic guided wave inspection. | LIU Zenghua ZHAO Jichen WU Bin HE Cunfu | 2011 | Chinese Journal of Mechanical Engineering2011，24，3： | 6 |
| 8 | Experimental Research on the Dynamic Lubricating Performance of Slipper/Swash Plate Interface in Axial Piston Pumps显示文摘The interface between the slipper/swash plate is one of the most important frication pairs in axial piston pumps.The test of this interface in a real pump is very challenging.In this paper,a novel pump prototype is designed and a test rig is set up to study the dynamic lubricating performance of the slipper/swash-plate interface in axial piston machines.Such an experimental setup can simulate the operating condition of a real axial piston pump without changing the relative motion relationship of the interfaces.Considering the lubricant oil film thickness as the main measurement parameter,the attitude of the slipper under the conditions of different load pressure,rotation speed and charge pressure are studied experimentally.After the test,the wear state of the swash plate is observed.According to the friction trace on the surface of the swash plate,the prediction for the attitude of the slipper and the zone easy to wear are verified. | Junjie Zhou Jichen Zhou Chongbo Jing | 2020 | Chinese Journal of Mechanical Engineering2020，33，2： | 5 |
| 9 | Experimental Study of Churning Losses in Swash Plate Axial Piston Pump显示文摘The problem of the churning loss in swash plate axial piston machines is investigated through experimental measurement and theoretical analysis. Several works surrounding churning loss in hydraulic components have been proposed in the past, but few have conducted experimental studies and accounted for both dry and wet housing conditions. In this study,a specialized experimental setup is established, which includes a transparent test pump diligently designed for performing various functions of tests. The test pump can work as a real pump without losing any actual features of pump operation. The torque loss in both the dry housing pump and wet housing pump is measured in terms of the shaft speed and its predictive model is also developed analytically. The comparisons between measured and calculated torque loss are presented, showing how speed influences torque loss in both conditions. The advantage/disadvantages of the two cases are summarized. The significance of the test setup is highlighted by verifying the proposed model, which can advance the understanding of energy losses of high speed pumps in future. | Chongbo Jing Junjie Zhou Jichen Zhou | 2019 | Journal of Beijing Institute of Technology2019，28，3： | 3 |
| 10 | Characterization of Bacterial Communities Associating with Larval Development of Yesso Scallop(Patinopecten yessoensisis Jay, 1857) by High-Throughput Sequencing显示文摘Bacterial community presumably plays an essential role in inhibiting pathogen colonization and maintaining the health of scallop larvae, but limiting data are available for Yesso scallop(Patinopecten yessoensisis Jay, 1857) larval development stages. The aim of this study was to characterize and compare the bacterial communities associating with Yesso scallop larval development at fertilized egg S1, trochophora S2, D-shaped larvae S3, umbo larvae S4, and juvenile scallop S5 stages by Illumina high-throughput sequencing. Genomic DNA was extracted from the larvae and their associating bactera, and a gene segment covering V3-V4 region of 16 S r RNA gene was amplified and sequenced using an Illumina Miseq sequencer. Overall, 106760 qualified sequences with an average length of 449 bp were obtained. Sequences were compared with those retrieved from 16 S r RNA gene databases, and 4 phyla, 7 classes, 15 orders, 21 families, 31 genera were identified. Proteobacteria was predominant phylum, accounting for more than 99%, at all 5 larval development stages. At genus level, Pseudomonas was dominant at stages S1(80.60%), S2(87.77%) and S5(68.71%), followed by Photobacterium(17.06%) and Aeromonas(1.64%) at stage S1, Serratia(6.94%), Stenotrophomonas(3.08%) and Acinetobacter(1.2%) at stage S2, Shewanella(25.95%) and Pseudoalteromonas(4.57%) at stage S5. Moreover, genus Pseudoalteromonas became dominant at stages S3(44.85%) and S4(56.02%), followed by Photobacterium(29.82%), Pseudomonas(11.86%), Aliivibrio(8.60%) and Shewanella(3.39%) at stage S3, Pseudomonas(18.16%), Aliivibrio(14.29%), Shewanella(4.11%), Psychromonas(4.04%) and Psychrobacter(1.81%) at stage S4. From the results, we concluded that the bacterial community changed significantly at different development stages of Yesso Scallop larvae. | SUN Xueying LIU Jichen LI Ming ZHAO Xuewei LIANG Jun SUN Pihai MA Yuexin | 2016 | Journal of Ocean University of China2016，15，6： | 3 |
| 11 | Genome sequencing and phylogenetic analysis of allotetraploid Salix matsudana Koidz显示文摘Polyploidy is a common phenomenon among willow species.In this study,genome sequencing was conducted for Salix matsudana Koidz(also named Chinese willow),an important greening and arbor tree species,and the genome of this species was compared with those of four other tree species in Salicaceae.The total genome sequence of S.matsudana was 655.72 Mb in size,with repeated sequences accounting for 45.97%of the total length.In total,531.43 Mb of the genome sequence could be mapped onto 38 chromosomes using the published genetic map as a reference.The genome of S.matsudana could be divided into two groups,the A and B genomes,through homology analysis with the genome of Populus trichocarpa,and the A and B genomes contained 23,985 and 25,107 genes,respectively.4DTv combined transposon analysis predicted that allotetraploidy in S.matsudana appeared~4 million years ago.The results from this study will help reveal the evolutionary history of S.matsudana and lay a genetic basis for its breeding. | Jian Zhang Huwei Yuan Yujuan Li Yanhong Chen Guoyuan Liu Meixia Ye Chunmei Yu Bolin Lian Fei Zhong Yuna Jiang Jichen Xu | 2020 | Horticulture Research2020，7，1： | 3 |
| 12 | Design and performance evaluation of a variable-rate orchard sprayer based on a laser-scanning sensor显示文摘To improve the precision spraying strategy and reduce excessive pesticide application in orchards,an air-assisted sprayer integrated with a laser-scanning system was developed to realize the toward-target variable-rate spraying.In the spray control system,a method of calculating canopy gridding volumes was designed to ensure that the canopy was divided into a uniform grid size,a variable-rate spray model was used in the flow rate decision software to control the spray output according to the canopy gridding volumes and travel speed,and a method of saving and accessing spray data was used to control the spray delay.The effects of different grid sizes and travel speeds on the spray performance were evaluated by quantifying spray coverage uniformity inside tree canopies.The results showed that spray coverage uniformity declined with increasing grid width from 0.14 to 0.28 m although the mean spray coverage on each target location showed no significant differences.Additionally,there were no significant variations in mean spray coverage at speeds of 1.0,1.2 and 1.4 m/s for a tested tree of 1.6 m width and at any experimental speeds for a tested tree of 1.3 m width,which indicated that the variable-rate sprayer could provide good spray coverage uniformity under various travel speeds with a canopy size limitation.Compared with the same sprayer without the variable-rate spray function,the intelligent sprayer prototype realized effective toward-target spraying and avoided overspraying while providing sufficient spray coverage. | Jichen Cai Xiu Wang Yuanyuan Gao Shuo Yang Chunjiang Zhao | 2019 | International Journal of Agricultural and Biological Engineering2019，12，6： | 2 |
| 13 | Identification of a New Rice Blast Resistance Gene, Pid3, by Genomewide Comparison of Paired Nucleotide-Binding Site-Leucine-Rich Repeat Genes and Their Pseudogene Alleles Between the Two Sequenced Rice Genomes显示文摘 | Shang Junjun Tao Yong Chen Xuewei Zou Yan Lei Cailin Wang Jing Li Xiaobing Zhao Xianfeng Zhang Meijun Lu Zhike Xu Jichen Cheng Zhukuan Wan Jianmin Zhu Lihuang | 2009 | Genetics2009，，4： | 2 |
| 14 | Response of microbial biomass and bacterial community composition to fertilization in a salt marsh in China显示文摘The effects of nitrogen(N) addition on microbial biomass, bacterial abundance, and community composition in sediment colonized by Suaeda heteroptera were examined by chloroform fumigation extraction method, real-time quantitative polymerase chain reaction, and denaturing gradient gel electrophoresis(DGGE) in a salt marsh located in Shuangtai Estuary, China. The sediment samples were collected from plots treated with different amounts of a single N fertilizer(urea supplied at 0.1, 0.2, 0.4 and 0.8 g/kg(nitrogen content in sediment) and different forms of N fertilizers(urea,(NH_4)_2SO_4, and NH_4NO_3, each supplied at 0.2 g/kg(calculated by nitrogen).The fertilizers were applied 1–4 times during the plant-growing season in May, July, August, and September of 2013. Untreated plots were included as a control. The results showed that both the amount and form of N positively influenced microbial biomass carbon, microbial biomass nitrogen, and bacterial abundance. The DGGE profiles revealed that the bacterial community composition was also affected by the amount and form of N.Thus, our findings indicate that short-term N amendment increases microbial biomass and bacterial abundance,and alters the structure of bacterial community. | MA Yuexin TAO Wei LIU Changfa LIU Jiao YANG Zhiping LI Jin LIU Jichen | 2017 | Acta Oceanologica Sinica2017，36，6： | 2 |
| 15 | Flocking shape analysis of multi-agent systems显示文摘In this paper,we consider the shape control in flocking behavior of a multi-agent system with a virtual leader.Besides the traditional flocking control terms,which include a gradient-based term,a velocity consensus term and a navigational feed-back in general,a new piecewise smooth neighbor-based local controller is added to regulate the configuration to the desired flocking shape.All agent velocities approach the desired velocity asymptotically,while collisions among agents can be avoided.Furthermore,based on the proved stability,we obtain three kinds of flocking shapes,such as those in a single line,vee shape or corner shape.Some numerical simulation results are provided to demonstrate theoretical issues. | YANG JiChen,LU QiShao &LANG XiuFeng Department of Dynamics and Control,Beihang University,Beijing 100191,China | 2010 | Science China(Technological Sciences)2010，53，3： | 2 |
| 16 | Catalytic Removal of PM by Li-Co Delafossite Catalysts显示文摘By using solution combustion synthesis method, several Li-Co delafossite catalysts were prepared via a highly exothermic and self-sustaining reaction. The prepared catalysts were characterized by XRD, SEM and the catalytic activities of the catalysts were evaluated by small sample experiment. It is shown that under loose contact conditions this catalyst can catalyze soot combustion at 360 ℃, and the best prepared catalyst Li Co0.9O2 can ignite soot combustion below 300 ℃. In the incompletely synthesized catalysts the Co cations shift to higher electrovalence, so the number of the surface adsorbed oxygen(O-) of the prepared delafossite catalysts increase and Li Co0.9O2 has the optimum catalytic activity. | 王伟 ZHANG Jichen 肖静 LUO Dabing | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，2： | 2 |
| 17 | Early changes to the extracellular space in the hippocampus under simulated microgravity conditions显示文摘The smooth transportation of substances through the brain extracellular space(ECS)is crucial to maintaining brain function;however,the way this occurs under simulated microgravity remains unclear.In this study,tracer-based magnetic resonance imaging(MRI)and DECS-mapping techniques were used to image the drainage of brain interstitial fluid(ISF)from the ECS of the hippocampus in a tail-suspended hindlimb-unloading rat model at day 3(HU-3)and 7(HU-7).The results indicated that drainage of the ISF was accelerated in the HU-3 group but slowed markedly in the HU-7 group.The tortuosity of the ECS decreased in the HU-3 group but increased in the HU-7 group,while the volume fraction of the ECS increased in both groups.The diffusion rate within the ECS increased in the HU-3 group and decreased in the HU-7 group.The alterations to ISF drainage and diffusion in the ECS were recoverable in the HU-3 group,but neither parameter was restored in the HU-7 group.Our findings suggest that early changes to the hippocampal ECS and ISF drainage under simulated microgravity can be detected by tracer-based MRI,providing a new perspective for studying microgravity-induced nano-scale structure abnormities and developing neuroprotective approaches involving the brain ECS. | Yajuan Gao Hongbin Han Jichen Du Qingyuan He Yanxing Jia Junhao Yan Hui Dai Bin Cui Jing Yang Xunbin Wei Liu Yang Rui Wang Ren Long Qiushi Ren Xing Yang Jiabin Lu | 2022 | Science China(Life Sciences)2022，65，3： | 2 |
| 18 | Nutrient removal performance and microbial community structure in an EBPR system under the limited filamentous bulking state显示文摘 | Xiong Yang Yongzhen Peng Nanqi Ren Jianhua Guo Xiaoxue Tang Jichen Song | 2013 | Bioresource Technology2013，，： | 2 |
| 19 | Risk factor comparison and clinical analysis of early and late bronchopleural fostula after non-small cell lung cancer surgery显示文摘 | Jichen QV Chen G Jiang G | 2009 | Ann Thoral Surg2009，88，5： | 1 |
| 20 | Risk factor comparison and clinical analysis of early and late bronchopleural fistula after non-small cell lung cancer surgery显示文摘 | Jichen QV Chen G Jiang G | 2009 | Ann Thorac Surg2009，88，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员