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| 1 | New innovations in pavement materials and engineering:A review on pavement engineering research 2021显示文摘Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges.In the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social economy.New theories,new methods,new technologies and new materials related to pavement engineering are emerging.Deterioration of pavement infrastructure is a typical multi-physics problem.Because of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material analysis.In order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of'New innovations in pavement materials and engineering:A review on pavement engineering research 2021'.Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the world.The content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent pavement.Overall,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering. | JTTE Editorial Office Jiaqi Chen Hancheng Dan Yongjie Ding Yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong Yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang Wei Jiang Cheng Li Pengfei Liu Yu Liu Zhuangzhuang Liu Guoyang Lu Jian Ouyang Xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang Yue Xiao Chao Xing Huining Xu Yu Yan Xu Yang Lingyun You Zhanping You Bin Yu Huayang Yu Huanan Yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou Xingyi Zhu | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，6： | 7 |
| 2 | Diagenesis and Diagenetic Evolution of Deltaic and Neritic Gas-Bearing Sandstones in the Lower Mingyuefeng Formation of Paleogene, Lishui Sag, East China Sea Shelf Basin: Implications for Depositional Environments and Sequence Stratigraphy Controls显示文摘Gas-bearing deposits in the Lower Mingyuefeng Formation of Paleogene, Lishui Sag, East China Sea Shelf Basin consist of shoreface sandstones of the highstand systems tract(HST) and transgressive systems tract(TST), and deltaic sandstones of the lowstand systems tract(LST) and falling stage systems tract(FSST).Detailed petrographic observations suggest that the diagenetic features and related evolution of these deposits cannot be simply characterized and demonstrated in the depth domain.However, the occurrence of diagenetic minerals systematically depends on the studied interval within the HST, TST, LST, and FSST; therefore, diagenesis in this region can be better constrained when studied in the context of the depositional environments and sequence stratigraphic framework.The eogenetic processes in such settings include:(1) microcrystalline siderite precipitated as concretions in almost all environments and systems tracts, which inhibited further mechanical compaction;(2) grain dissolution and kaolinitization occurred in shoreface HST sandstones and deltaic LST and FSST sandstones;(3) glaucony was locally observed, which did not clearly reflect the controls of facies or sequence stratigraphy; and(4) cementation by pyrite aggregates occurred in the shoreface HST sandstones and deltaic LST sandstones.The mesogenetic diagenesis includes:(1) partial conversion of kaolinite into dickite in deltaic LST sandstones, and minor chlorite cementation in deltaic FSST sandstones;(2) transformation of kaolinite into illite and quartz cementation in deltaic LST and FSST sandstones;(3) frequent precipitation of ankerite and ferroan calcite in shoreface TST sandstones and early HST sandstones, forming baffles and barriers for fluid flow, with common calcite in shoreface HST sandstones as a late diagenetic cement; and(4) formation of dawsonite in the deltaic LST and FSST sandstones, which is interpreted to be a product of the invasion of a CO2-rich fluid, and acts as a good indicator of CO2-bearing reservoirs.This study has thus constructed a reliable conceptual model to describe the spatial and temporal distribution of diagenetic alterations.The results may provide an entirely new conceptual framework and methodology for successful gas exploration in the continental margins of offshore China, thus allowing us to predict and unravel the distribution and quality evolution of clastic reservoirs at a more detailed and reliable scale. | XU Fa ZHANG Penghui ZHANG Jinliang LIU Jinshui HOU Guowei ZHANG Ming LI Jingzhe LIU Shasha GUO Jiaqi MENG Ningning | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 5 |
| 3 | Decentration and tilt of plate-haptic multifocal intraocular lenses in myopic eyes显示文摘Background:To investigate the decentration and tilt of plate-haptic multifocal intraocular lenses(MfIOLs)in myopic eyes.Methods:Myopic(axial length[AXL]>24.5 mm)and non-myopic(21.0 mm | Jiaqi Meng Wenwen He Xianfang Rong Ao Miao Yi Lu Xiangjia Zhu | 2020 | Eye and Vision2020，7，1： | 5 |
| 4 | Network pharmacological prediction and molecular docking analysis of the combination of Atractylodes macrocephala Koidz.and Paeonia lactiflora Pall.in the treatment of functional constipation and its verification显示文摘Background:We aimed to reveal the mechanism of functional constipation in the treatment of Atractylodes macrocephala Koidz.(AMK)and Paeonia lactiflora Pall.(PLP).Methods:The main active ingredients of AMK and PLP were screened by the Traditional Chinese Medicine Systems Pharmacology(TCMSP)platform.A database of functional constipation targets was established by GeneCard and OMIM.An“ingredient-target”network map was constructed with Cytoscape software(version 3.7.1),and molecular docking analysis was performed on the components and genes with the highest scores.The rats in the normal group were given saline,and those in the other groups were given 10 mg/kg diphenoxylate once a day for 14 days.The serum and intestinal tissue levels of adenosine monophosphate(cAMP),protein kinase A(PKA),and adenylyl cyclase(AC)of the rats and aquaporin(AQP)1,AQP3,and AQP8 were measured.Results:AMK and PLP had a significant role in the regulation of targets in the treatment of functional constipation.After treatment with AMK,PLP,or mosapride,the serum and intestinal tissue levels of AC,cAMP,and PKA were significantly downregulated.Groups receiving AMK and PLP or mosapride exhibited a reduction in the level of AQP1,AQP3,and AQP8 to varying degrees.Conclusion:Molecular docking analysis revealed that AMK and PLP had a significant role in the regulation of targets in the treatment of functional constipation.Studies have confirmed that AMK and PLP can also affect AC,cAMP,and PKA.AC,cAMP,and PKA in model rats were significantly downregulated.AQP expression is closely related to AC,cAMP,and PKA.AMK and PLP can reduce the expression of AQP1,AQP3,and AQP9 in the colon of constipated rats. | Yuxiao Meng Xiaojun Li Xiaoting Wang Lu Zhang Jiaqi Guan | 2022 | Animal Models and Experimental Medicine2022，5，2： | 4 |
| 5 | Enzyme-electrolytic degradation of dichloromethane: Efficiency, kinetics and mechanism显示文摘Enzymatic electrolysis cell(EEC)has advantages over microbial electrolysis cell(MEC)due to the needless of microbe inoculation and high-efficiency of enzymatic reaction.In this study,an EEC was first applied to achieve the effective degradation of halogenated organic pollutants and dichloromethane(CH2Cl2)was utilized as a model pollutant.The results indicate that the degradation efficiency of CH2Cl2 after 2 hr reaction in the EEC was almost100%,which was significantly higher than that with enzyme(51.1%)or current(19.0%).The current induced the continuous regeneration of reduced glutathione(GSH),thus CH2Cl2 was degraded under the catalysis of GSH-dependent dehalogenase through stepwise dechlorination,and successively formed monochloromethane(CH3Cl)and methane(CH4).The kinetic result shows that with a current of 15 mA,the maximum specific degradation rate of CH2Cl2(3.77×10-3 hr-1)was increased by 5.7 times.The optimum condition for CH2Cl2 dechlorination was also obtained with pH,current and temperature of 7.0,15 mA and 35°C,respectively.Importantly,this study helps to understand the behavior of enzymes and the fate of halogenated organic pollutants with EEC,providing a possible treatment technology for halogenated organic pollutants. | Jianming Yu Meng Wu Yuwei Tang Jiaqi Shi Jun Hu Zhiliang Yu Jianmeng Chen | 2019 | Journal of Environmental Sciences2019，31，12： | 3 |
| 6 | Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs显示文摘An in vitro blood-brain barrier(BBB) model is critical for enabling rapid screening of the BBB permeability of the drugs targeting on the central nervous system.Though many models have been developed, their reproducibility and renewability remain a challenge. Furthermore, drug transport data from many of the models do not correlate well with the data for in vivo BBB drug transport.Induced-pluripotent stem cell(i PSC) technology provides reproducible cell resources for in vitro BBB modeling.Here, we generated a human in vitro BBB model by differentiating the human i PSC(hi PSC) line GM25256 into brain endothelial-type cells. The model displayed BBB characteristics including tight junction proteins(ZO-1,claudin-5, and occludin) and endothelial markers(von Willebrand factor and Ulex), as well as high transendothelial electrical resistance(TEER)(1560 X.cm2±230 X.cm2) and c-GTPase activity. Co-culture with primary rat astrocytes significantly increased the TEER of the model(2970 X.cm2 to 4185 X.cm2). RNAseq analysis confirmed the expression of key BBB-related genes in the hi PSC-derived endothelial cells in comparison with primary human brain microvascular endothelial cells,including P-glycoprotein(Pgp) and breast cancer resistant protein(BCRP). Drug transport assays for nine CNS compounds showed that the permeability of non-Pgp/BCRP and Pgp/BCRP substrates across the model was strongly correlated with rodent in situ brain perfusion data for these compounds(R2= 0.982 and R2= 0.9973,respectively), demonstrating the functionality of the drug transporters in the model. Thus, this model may be used to rapidly screen CNS compounds, to predict the in vivo BBB permeability of these compounds and to study the biology of the BBB. | Yuan Li Xueying Sun Houfu Liu Liang Huang Guofeng Meng Yu Ding Wenji Su Jiaqi Lu Sophie Gong Georg C.Terstappen Ru Zhang Wandong Zhang | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 7 | Applying accurate gradients of seismic wave reflection coefficients (SWRC) to the inversion of seismic wave velocities显示文摘Through solving the Zoeppritz's partial derivative equations, we have obtained accurate partial derivatives of reflected coefficients of seismic wave with respect to Pand S-wave velocities.With those partial derivatives, a multi-angle inversion is developed for seismic wave velocities.Numerical examples of different formation models show that if the number of iterations goes over 10, the relative error of inversion results is less than 1%, whether or not there is interference among the reflection waves.When we only have the reflected seismograms of P-wave, and only invert for velocities of P-wave, the multi-angle inversion is able to obtain a high computation precision.When we have the reflected seismograms of both P-wave and VS-wave, and simultaneously invert for the velocities of P-wave and VS-wave, the computation precisions of VS-wave velocities improves gradually with the increase of the number of angles, but the computation precision of P-wave velocities becomes worse.No matter whether the reflected seismic waves from the different reflection interface are coherent or non-coherent, this method is able to achieve a higher computation precision.Because it is based on the accurate solution of the gradient of SWRCs without any additional restriction, the multi-angle inversion method can be applied to seismic inversion of total angles.By removing the difficulties caused by simplified Zoeppritz formulas that the conventional AVO technology struggles with, the multiangle inversion method extended the application range of AVO technology and improved the computation precision and speed of inversion of seismic wave velocities. | LIU FuPing MENG XianJun XIAO JiaQi WANG YuMei SHEN GuoQiang | 2012 | Science China Earth Sciences2012，55，12： | 3 |
| 8 | Stable perovskite solar cells with efficiency of 22.6%via quinoxaline-based polymeric hole transport material显示文摘Poor stability of spiro-OMe TAD hole transport materials(HTMs)with dopant is a major obstacle for the commercialization of perovskite solar cells(pero-SCs).Herein,we demonstrate a series of quinoxaline-based D-A copolymers PBQ5,PBQ6 and PBQ10 as the dopant-free polymer HTMs for high performance pero-SCs.The D-A copolymers are composed of fluorothienyl benzodithiophene(BDTT)as D-unit,difluoroquinoxaline(DFQ)with different side chains as A-unit,and thiophene asπ-bridge,where the side chains on the DFQ unit are bi-alkyl for PBQ5,bi-alkyl-fluorothienyl for PBQ6,and alkoxyl for PBQ10.All the three copolymers are adopted as the dopant-free HTM in the pero-SCs.The planar n-i-p structured pero-SCs based on(FAPb I_(3))_(0.98)(MAPb Br_(3))_(0.02)with PBQ6 HTM demonstrated the high power conversion efficiency(PCE)of 22.6%with Vocof1.13 V and FF of 80.8%,which is benefitted from the suitable energy level and high hole mobility of PBQ6.The PCE of 22.6%is the highest efficiency reported in the n-i-p structured pero-SCs based on dopant-free D-A copolymer HTM.In addition,the peroSCs show significantly enhanced ambient,thermal and light-soaking stability compared with the devices with traditional spiroOMe TAD HTM. | Chenxing Lu Can Zhu Lei Meng Chenkai Sun Wenbin Lai Shucheng Qin Jinyuan Zhang Wenchao Huang Jiaqi Du Yiyang Wang Yongfang Li | 2021 | Science China Chemistry2021，64，11： | 2 |
| 9 | Lens thickness and associated ocular biometric factors among cataract patients in Shanghai显示文摘Background:To evaluate the distribution of lens thickness(LT)and its associations with other ocular biometric factors among cataract patients in Shanghai.Methods:Twenty-four thousand thirteen eyes from 24,013 cataract patients were retrospectively included.Ocular biometric factors including LT,central corneal thickness(CCT),anterior chamber depth(ACD),white-to-white(WTW)distance,anterior corneal curvature,and axial length(AL)were obtained using the IOLMaster700.The associations between LT and general or ocular factors were assessed.Results:The mean age was 62.5±13.6 years and 56.1%were female.The mean LT was 4.51±0.46 mm.The LT was greater in older patients(P<0.001).LT was positively correlated with CCT,while negatively correlated with ACD,WTW,and anterior corneal curvature(P<0.001).Multivariate analysis revealed that increased LT was associated with older age,male gender,thicker CCT,shallower ACD,larger WTW,and flatter anterior corneal curvature(P<0.001).LT changed with a variable behavior according to AL.In short eyes LT increased as AL increased,then decreased with longer AL in normal eyes and moderate myopic eyes,but increased again as AL increased in highly myopic eyes.Thickest LT was found in the 20.01-22mm AL group.The correlation between LT and other biometric factors remained significant when stratified by ALs.Conclusions:In a large Chinese cataractous population,we found that the thicker lens may be associated with older age,male gender,thicker CCT,shallower ACD,larger WTW,and flatter anterior corneal curvature.As AL increased,the change of LT was nonlinear,with the thickest lens seen in the 20-22mm AL group. | Jiaqi Meng Ling Wei Wenwen He Jiao Qi Yi Lu Xiangjia Zhu | 2021 | Eye and Vision2021，8，1： | 2 |
| 10 | bZIP71 delays flowering by suppressing Ehd1 expression in rice显示文摘Flowering time is a fundamental factor determining the global distribution and final yield of rice(Oryza sativa).Although diverse flowering time genes have been reported in this crop,the transcriptional regulation of its key flowering genes are poorly understood.Here,we report that a basic leucine zipper transcription factor,bZIP71,functions as a flowering repressor.The overexpression of bZIP71 delays flowering,while the bzip71 mutant flowers early in both long-day and short-day conditions.A genetic analysis showed that the regulation of flowering by bZIP71 might be independent of Heading date 2(Hd2),Hd4,and Hd5.Importantly,bZIP71 directly associates with the Early heading date 1(Ehd1)promoter and represses its transcription,and genetically the function of bZIP71 is impaired in the ehd1 mutant.Moreover,bZIP71 interacts with major components of polycomb repressive complex 2(PRC2),SET domain group protein 711(SDG711),and Fertilization independent endosperm 2(FIE2),through which bZIP71 regulates the H3K27me3 level of Ehd1.Taken together,we present a transcriptional regulatory mechanism in which bZIP71 enhances the H3K27me3 level of Ehd1 and transcriptionally represses its expression,which not only offers a novel insight into a flowering pathway,but also provides a valuable putative target for the genetic engineering and breeding of elite rice cultivars. | Xiufeng Li Xiaojie Tian Mingliang He Xinxin Liu Zhiyong Li Jiaqi Tang Enyang Mei Min Xu Yingxiang Liu Zhenyu Wang Qingjie Guan Wei Meng Jun Fang Jian Zhang Qingyun Bu | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 11 | LD-Pumped Random Fiber Laser Based on Erbium-Ytterbium Co-Doped Fiber显示文摘In this paper,a cladding-pumped erbium-ytterbium co-doped random fiber laser(EYRFL)operating at 1550 nm with high power laser diode(LD)is proposed and experimentally demonstrated for the first time.The laser cavity includes a 5-m-long erbium-ytterbium co-doped fiber that serves as the gain medium,as well as a 2-km-long single-mode fiber(SMF)to provide random distributed feedback.As a result,stable 2.14 W of 1550 nm random lasing at 9.80 W of 976 nm LD pump power and a linear output with the slope efficiency as 22.7%are generated.This simple and novel random fiber laser could provide a promising way to develop high power 1.5μm light sources. | Qingyang MENG Han WU Bing HAN Jiaqi LI Zinan WANG | 2020 | Photonic Sensors2020，10，2： | 1 |
| 12 | Correlations between substrate bias, microstruc- ture and surface morphology of tetrahedral amor- phous carbon films显示文摘 | ZHU Jiaqi HAN Jiecai MENG Songhe | 2004 | Vacuum2004，72，： | 1 |
| 13 | A novel P-doped and NCDs loaded g-C_(3)N_(4) with enhanced charges separation for photocatalytic hydrogen evolution显示文摘Graphite carbon nitride(g-C_(3)N_(4)) is a promising non-metal photocatalyst for photocatalytic hydrogen production, but its performance is still limited due to sluggish charges separation and low utilization of light.In this work, P-doped and N-doped carbon dots(NCDs) supported g-C_(3)N_(4)were successfully prepared via hydrothermal and polymerization reactions. The sub-bandgap formed by P-doping enhances the utilization of visible light, and the high electron density of P sites is conducive to the trapping of holes. NCDs also improve light utilization and, more importantly, act as electron acceptors and transporters to promote electron transport. The built-in electric field formed by the synergy of P-doping and NCDs-loading greatly promotes the separation of charges. The PCN/NCDs showed a significantly improved hydrogen evolution activity of 3731 μmol h^(-1)g^(-1), which was 6.7 times that of pure carbon nitride(560 μmol h^(-1)g^(-1)). This strategy may be generalized to the design of g-C_(3)N_(4)-based photocatalysts, facilitating the separation of charges for enhanced catalytic activity. | Shuaiyang Zhang Yan Yang Yunpu Zhai Jiaqi Wen Meng Zhang Jingkun Yu Siyu Lu | 2023 | Chinese Chemical Letters2023，34，4： | 1 |
| 14 | Chlorinated polymerized small molecule acceptor enabling ternary all-polymer solar cells with over 16.6% efficiency显示文摘Recently,all-polymer solar cells(all-PSCs) based on polymerized small molecule acceptors(PSMAs) have achieved significant progress.Ternary blending has proven to be an effective strategy to further boost the power conversion efficiency(PCE) of the all-PSCs.Herein,a new A-DA′D-A small-molecule acceptor-based PSMA(named as PYCl-T) was designed and synthesized,which possesses similar polymer backbone with the widely used PY-IT,but with chlorine substitution on the A-end groups in the A-DA′D-A structure.PYCl-T was then employed as the third component into the PM6:PY-IT system and the ternary all-PSCs based on PM6:PY-IT:PYCl-T demonstrated a high PCE of 16.62%(certified value of 16.3%).Moreover,the PCE of 15.52% was realized in the enlarged ternary all-PSCs with effective area of 1 cm^(2),indicating the great potential in large-scale applications.Moreover,the optimized ternary blend films of PM6:PY-IT:PYCl-T show excellent thermal stability at 150 ℃.This work demonstrates that the utilization of a ternary blend system involving two well-compatible PSMA polymer acceptors is an effective strategy to boost the performance of the all-PSCs. | Ke Hu Jiaqi Du Can Zhu Wenbin Lai Jing Li Jingming Xin Wei Ma Zhanjun Zhang Jinyuan Zhang Lei Meng Yongfang Li | 2022 | Science China Chemistry2022，65，5： | 1 |
| 15 | The Goos-Hnchen shift of wide-angle seismic reflection wave显示文摘The partial derivative equations of Zoeppritz equations are established and the derivatives of each matrix entry with respect to wave vectors are derived in this paper.By solving the partial derivative equations we obtained the partial derivatives of seismic wave reflection coefficients with respect to wave vectors,and computed the Goos-Hnchen shift for reflected P-and VS-waves.By plotting the curves of Goos-Hnchen shift,we gained some new insight into the lateral shift of seismic reflection wave.The lateral shifts are very large for glancing wave or the wave of the incidence angle near the critical angle,meaning that the seismic wave propagates a long distance along the reflection interface before returning to the first medium.For the reflection waves of incidence angles away from the critical angle,the lateral shift is in the same order of magnitude as the wavelength.The lateral shift varies significantly with different reflection interfaces.For example,the reflected P-wave has a negative shift at the reflection interface between mudstone and sandstone.The reflected VS-wave has a large lateral shift at or near the critical angle.The lateral shift of the reflected VS-wave tends to be zero when the incidence angle approaches 90°.These observations suggest that Goos-Hnchen effect has a great influence on the reflection wave of wide-angles.The correction for the error caused by Goos-Hnchen effect,therefore,should be made before seismic data processing,such as the depth migration and the normal-moveout correction.With the theoretical foundation established in this paper,we can further study the correction of Goos-Hnchen effect for the reflection wave of large incidence angle. | LIU FuPing MENG XianJun XIAO JiaQi WANG AnLing YANG ChangChun | 2012 | Science China Earth Sciences2012，55，5： | 1 |
| 16 | Dynamic shielding of bacterial outer membrane vesicles for safe and efficient chemo-immunotherapy against tumors显示文摘Bacterial outer membrane vesicles(OMVs)are potent immunostimulants of regulating the tumor microenvironment(TME)for immunotherapy,and can be used to deliver drugs.However,the severe systemic inflammatory response triggered by OMVs upon intravenous(i.v.)injection has limited their application.Here,we developed a safe and effective strategy by conjugating doxorubicin-loaded serum albumin(SA-DOX,AD)onto the surface of OMVs using a matrix metalloproteinase(MMP)-cleavable peptide linker(cL).This approach enabled the dynamic shielding of OMVs to reduce the systemic side effects while simultaneously enhancing the anti-tumor effects through chemo-immunotherapy.Specifically,the resulting OMV-cL-AD formulation exhibited significantly enhanced accumulation at the tumor site after i.v.administration,facilitated by the SA decoration on the OMVs surface.Subsequently,the shield on the OMV-cL-AD was cleaved by the over-expressed MMP in the TME,leading to the release of both OMVs and AD.This process provided OMV-induced immunotherapy and DOX-induced chemotherapy,resulting in synergistic tumor inhibition.In conclusion,our work demonstrated the potential of OMV-cL-AD as an effective immunochemotherapy strategy that can prolong the survival time of mice without inducing side effects. | Shuping Li Xin Li Jiaqi Meng Weier Bao Shuang Wang Peng Ye Xiao-Dong Gao Wei Wei | 2024 | Nano Research2024，17，2： | 1 |
| 17 | Wind regimes and associated sand dune types in the hinterland of the Badain Jaran Desert,China显示文摘Wind controls the formation and development of sand dunes.Therefore,understanding the wind regimes is necessary in sand dune research.In this study,we combined the wind data from 2017 to 2019 at four meteorological stations(Cherigele and Wuertabulage stations in the lake basins,and Yikeri and Sumujilin stations on the top of sand dunes)in the hinterland of the Badain Jaran Desert in China,with high resolution Google Earth images to analyze the correlation between the wind energy environments and dune morphology.The results of data analysis indicated that both the wind direction and sand drift intensity exhibited notable spatial and temporal variations.The highest level of wind activity was observed in spring.Northwesterly and northeasterly winds were the dominant in the Badain Jaran Desert.At the Cherigele,Wuertabulage,and Yikeri stations,the drift potential(DP)was below 200.00 vector units(VU).The wind energy environments in most areas could be classified as low-energy environments.The resultant drift direction differed at different stations and in different seasons,but the overall direction was mainly the southeast.The resultant drift potential(RDP)/DP ratio was greater than 0.30 in most parts of the study area,suggesting that the wind regimes mainly exhibited unimodal or bimodal characteristics.Differences between the thermodynamic properties and the unique landscape settings of lakes and sand dunes could alter the local circulation and intensify the complexity of the wind regimes.The wind regimes were weaker in the lake basins than on the top of sand dunes.Transverse dunes were the most dominant types of sand dunes in the study area,and the wind regimes at most stations were consistent with sand dune types.Wind was thus the main dynamic factor affecting the formation of sand dunes in the Badain Jaran Desert BJD.The results of this study are important for understanding the relationship between the wind regimes and aeolian landforms of the dune field in the deserts. | MENG Nan WANG Nai'ang ZHAO Liqiang NIU Zhenmin SUN Jiaqi | 2022 | Journal of Arid Land2022，14，5： | 1 |
| 18 | Correlations be- tween substrate bias, microstructure and surface morphology of tetrahedral amorphous carbon films 显示文摘 | Zhu Jiaqi Hart Jiecai Meng Songhe | 2004 | Vaccum2004，72，3： | 1 |
| 19 | LATS1 K751 acetylation blocks activation of Hippo signalling and switches LATS1 from a tumor suppressor to an oncoprotein显示文摘Large tumor suppressor 1(LATS1)is the key kinase controlling activation of Hippo signalling pathway.Post-translational modifications of LATS1 modulate its kinase activity.However,detailed mechanism underlying LATS1 stability and activation remains elusive.Here we report that LATS1 is acetylated by acetyltransferase CBP at K751 and is deacetylated by deacetylases SIRT3 and SIRT4.Acetylation at K751 stabilized LATS1 by decreasing LATS1 ubiquitination and inhibited LATS1 activation by reducing its phosphorylation.Mechanistically,LATS1 acetylation resulted in inhibition of YAP phosphorylation and degradation,leading to increased YAP nucleus translocation and promoted target gene expression.Functionally,LATS1-K751 Q,the acetylation mimic mutant potentiated lung cancer cell migration,invasion and tumor growth,whereas LATS1-K751 R,the acetylation deficient mutant inhibited these functions.Taken together,we demonstrated a previously unidentified post-translational modification of LATS1 that converts LATS1 from a tumor suppressor to a tumor promoter by suppression of Hippo signalling through acetylation of LATS1. | Siyuan Yang Weizhi Xu Cheng Liu Jiaqi Jin Xueying Li Yuhan Jiang Lei Zhang Xianbin Meng Jun Zhan Hongquan Zhang | 2022 | Science China(Life Sciences)2022，65，1： | 1 |
| 20 | Evaluation and Selection of the Optimal Scheme of Industrial Structure Adjustment Based on DEA显示文摘In the paper, the advanced assessment method of DEA (Date Envelopment Analysis) had been used to evaluate relative efficiency and select the optimal scheme of agricultural industrial structure adjustment. According to the results of DEA models, we analyzed scale benefits of every optional schemes, probed deeply the ultimate reason for not DEA efficient, which clarified the method and approach to improve these optional schemes. Finally, a new method had been proposed to rank and select the optimal scheme. The research is significant to direct the practice of the adjustment of agricultural industrial structure. | FU Lifang GE Jiaqi MENG Jun | 2006 | Journal of Northeast Agricultural University(English Edition)2006，13，1： | 1 |
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