|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Grain filling of cereals under soil drying显示文摘 | Yang, JC Zhang, JH | 2006 | 中国生物学文摘2006，20，2： | 92 |
| 2 | 自发性脑出血诊疗指南--美国心脏协会/美国卒中协会的健康职业者指南显示文摘在世界范围内,自发性、非创伤性脑出血(intracranial hemorrhage,ICH)仍然是致死、致残的重要原因。虽然在临床研究及治疗指南的临床证据方面,ICH一直落后于缺血性卒中和动脉瘤性蛛网膜下腔出血,但在过去的10年内有了长足的增长。基于人群的研究发现,出血量较小的ICH患者几乎均能通过良好的内科治疗而存活[1],提示良好的内科治疗很可能直接影响ICH患者的残疾率。本指南的目的是,纳入最新临床研究的中期结果,并更新2010年版指南[2],向临床医师强调,其管理对ICH患者结局有着重要影响,并为临床管理提供相应的循证医学证据。为保证本指南的简洁和实用性,ICH的背景及流行病学均被省略,仅提供参考文献供查阅[1,3-4]。 | Hemphill JC Ⅲ Greenberg SM Anderson CS 文婉玲 于瀛 黄清海 | 2015 | 中国脑血管病杂志2015，12，9： | 85 |
| 3 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病源性轻度认知障碍诊断标准推荐显示文摘美国国立老化研究所(NIA)和阿尔茨海默病协会(ADA)组织了一个工作组,负责阿尔茨海默病(AD)痴呆前症状阶段——即本文所称的AD源性轻度认知障碍(MCI)的诊断标准的制订及完善。该工作组制订了以下两套标准:(1)在缺乏相应条件进行先进影像技术及脑脊液检查时,医务人员适用的核心临床标准;(2)适用于包括临床试验在内的科学研究的研究标准。后者纳入了基于影像技术及脑脊液检查的生物标志物的应用。并根据所出现的生物标志物的性质,将最终MCI诊断的确定性程度分为4个级别。而要使生物标志物有效应用于诊断,并在社区医疗服务中规范使用,尚需做大量的工作。 | McKhann GM Knopman DS Chertkow H Hyman BT Jack CR Jr Kawas CH Klunk WE Koroshetz WJ Manly JJ Mayeux R Mohs RC Morris JC Rossor MN Schehens P Carrillo MC Thies B Weintraub S Phelps CH 贾建平(译) 陆璐(译) 张逸驰(译) 黄丽黄(译) 礼媛(译) | 2012 | 中华神经科杂志2012，45，5： | 51 |
| 4 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病痴呆诊断标准的推荐显示文摘由美国国立老化研究所(NIA)和阿尔茨海默病(AD)协会组织了一个工作组,负责修订1984年版AD痴呆的诊断标准。旨在确保修订后的标准具有足够的灵活性,既可供缺乏神经心理学测验、先进的影像技术和脑脊液检查措施的普通医务人员使用,也可供具备上述措施的科研、临床试验的专业研究者使用。新的标准广泛适用于各种原因的痴呆以及专门针对AD痴呆的标准,保留了1984年版标准中的“很可能的AD痴呆”的总体框架。在过去27年的经验基础上,工作组对临床诊断标准做了一些修改,保留了“可能的AD痴呆”的术语,但对其进行了更有针对性的重新定义。在科研用的“很可能的和可能的AD痴呆”的诊断标准中纳入了生物标志物证据。AD痴呆的核心临床标准仍将是临床实践中诊断的基础,但用生物标志物证据来提高AD痴呆诊断的病理生理学特异性也被人们寄予厚望。要实现AD痴呆的生物标志物诊断,还有许多工作摆在面前。 | McKhann GM Knopman DS Chertkow H Hyman BT Jack CR Jr Kawas CH Klunk WE Koroshetz WJ Manly J J Mayeux R Mohs RC Morris JC Rossor MN Scheltens P Carrillo MC Thies B Weintraub S Phelps CH 贾建平(译) 陆璐(译) 张逸驰(译) 黄丽(译) 韩阅(译) | 2012 | 中华神经科杂志2012，45，5： | 52 |
| 5 | “灰区”慢性乙型肝炎患者的分布及临床特征显示文摘【据Journal of Viral Hepatitis 2021年7月报道】题:“灰区”慢性乙型肝炎患者的分布及临床特征(作者Yao KF等)临床上存在相当一部分慢性乙型肝炎(CHB)患者的免疫状态无法分期,被认为处于“灰区”(GZ)。本研究旨在探究“灰区”CHB患者的分布及其临床特征。来自南京大学医学院附属鼓楼医院感染科的Yao等回顾性纳入了2016年1月-2020年8月未接受抗病毒治疗的CHB患者4759例。根据2018年美国肝病学会乙型肝炎防治指南对入组患者的免疫状态进行评判。 | YAO KF LIU JC WANG J 姚可方 黄睿 吴超 | 2021 | 临床肝胆病杂志2021，37，10： | 33 |
| 6 | 江苏省疟疾流行地理信息系统预测模型的研究显示文摘目的 建立江苏省疟疾地理信息系统 (GIS)数据库和疟疾流行GIS模型 ,对江苏省的疟疾流行区进行空间分析。方法 在ArcView 3 0a软件中建立江苏省疟疾流行病学GIS数据库 ,从世界粮农组织的FAOCLIM气象资料库中提取出江苏省及其周边地区的气象数据 ,计算疟原虫生长发育累积度 日 (TGDD) ,在ArcView 3 0a软件支持下对TGDD进行空间分析。结果 获江苏省疟疾TGDD预测分布图 ,江苏省疟疾流行的程度由西向东逐渐减轻 ,并可分为 3个地带 ;获江苏省 14年疟疾平均发病率分布图 ,江苏省中部、西部地区疫情较重 ,江南太湖流域的苏、锡、常地区、南通及江苏北部边界少数县疫情较轻 ,其他地区的发病率介于两者之间 ,江苏省 14年疟疾平均发病率分布图与江苏省疟疾TGDD预测分布图基本吻合。 | 杨国静 周晓农 JB Malone JC McCarroll 汪天平 刘建翔 高琪 张小萍 洪青标 孙乐平 | 2002 | 中华预防医学杂志2002，36，2： | 34 |
| 7 | 中国卫生地理信息系统基础数据库的构建显示文摘目的 构建可用于中国卫生地理信息系统 (GIS)应用研究的基础数据库 ,以合理应用已有的数据资源 ,并成为一个空间决策系统。方法 采集不同资料来源 ,经统一标化后构成基本资料源。主要的资料源包括 :(1 )覆盖中国地区的卫星遥感图片库 ;(2 )GIS数字化地图库 ;(3)疾病资料库与相关模型库。结果 已获卫星遥感图片库中的植被指数遥感图片、地面温度遥感图片、数字化高程图片、数字化土地利用图片等 ;GIS数字化地图库中的中国行政区划数字化地图、环境数据矢量地图、人口分布图、气象资料分布图等 ;疾病资料库与相关模型库中包括了多种疾病的调查报告、疾病防治年报表等资料 ,以及疾病的传播模型和媒介 中间宿主潜在自然孳生地模型 ,及恶性肿瘤发病因素相关图。结论 该数据库的构建使不同来源的数据达到统一性 ,数据库收集的数据量以足能为国内卫生专业人员应用为前提 ,希望通过更多疾病的应用 。 | 周晓农 胡晓抒 杨国静 洪青标 孙乐平 孙宁生 汪天平 JB Malong JC McCarroll 林丹丹 张治英 徐德忠 | 2003 | 中华流行病学杂志2003，24，4： | 25 |
| 8 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 9 | 枸橼酸氯米芬加二甲双胍和枸橼酸氯米芬加安慰剂在新近诊断为多囊卵巢综合征妇女诱导排卵中的作用显示文摘 | Moll E Bossuyt PM Korevaar JC 菅鑫妍 | 2006 | 中国处方药2006，5，9： | 23 |
| 10 | Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells显示文摘:AIM To construct Hsp90 antisense RNAeukaryotic expression vector, transfect it intoSGC7901 and SGC7901/VCR of MDR-type humangastric cancer cell lines, HCC7402 of humanhepatic cancer and Eel09 of human esophagealcancer cell lines, and to study the cell cycledistribution of the gene transected cells andtheir response to chemotherapeutic drugs.METHODS A I .03kb cDNA sequence of Hsp90Pwas obtained from the primary plasmid phHsp90by EcoR 1 and BamH I nuclease digestion andwas cloned to the EcoR 1 and BamH 1 site ofthe pcDNA by T4DNA ligase and an antisenseorientation of Hsp900 expression vector wasconstructed. The constructs were transfectedwith lipofectamine and positive clones wereselected with G418. The expression of RNA wasdetermined with dot blotting and RNaseprotection assay, and the expression of Hsp90protein determined with Western blot. Cell cycledistribution of the transfectants was analyzedwith flow cytometry, and the drug sensitivity ofthe transfectants to adriamycin (ADR ),vincrinstine (VCR ), mitomycin (MMC ) andcyclophosphamide (CTX ) with MTT andintracellular drug concentration of thetransfectants was determined with flowcytometry.RESULTS In EcoR 1 and BamH I restrictionanalysis, the size and the direction of the clonedsequence of Hsp900 remained what had beendesigned and the gene constructs were namedpcDNA-Hsp90. AH^SGC7901, AH^SGC7901/ VCR,AH-HCC7402 and AH-Eel09 cell clones allexpressed Hsp90 anti--sense RNA. Theexpression of Hsp90 was down--regulated in AHSGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH--Eel09 cell clones. Cell cycle distribution waschanged differently. In AH-SGC7901/ VCR andAH-Ec109 cells, G, phase cells were increased; Sphase and G, phase cells were decreased ascompared with their parental cell lines. In AHSGC7901 cell, G, phase cells were decreased, Qphase cells increased and S phase cells were notchanged, and in AH-HCC7402 cells G,, S and qphase cells remained unchanged as comparedwith their parental cell lines. The sensitivity ofAH--SGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH-Ec109 to chemotherapeutic drugs, thesensitivity ot AH--SGC7901/ VCR to ADR, VCR,MMC and CTX the sensitivity of AH-HCC7402 toADR and VCR, and the sensitivity of Eel09 toADR, VCR and CTX all increased as comparedwith their parental cell lines. The meanfluorescence intensity of ADR in AH--SGC7901,AH-SGC7901/ VCR, AH--HCC7402 and AH-Ec109was also significantly elevated (P< 0. 05).CONCLUSION Down-regulation of HsP90 couldchange cell cycle distribution and increase thedrug sensitivity of tumor cells. | Liu XL Xiao B Yu ZC Guo JC Zhao QC Xu L Shi YQ Fan DM | 1999 | World Journal of Gastroenterology1999，5，3： | 21 |
| 11 | Current status of laparoscopic and robotic ventral mesh rectopexy for external and internal rectal prolapse显示文摘External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated with a higher recurrence rate, an abdominal approach is commonly preferred. Despite the description of greater than three hundred different procedures, thus far no clear superiority of one surgical technique has been demonstrated. Ventral mesh rectopexy(VMR) is a relatively new and promising technique to correct rectal prolapse. In contrast to the abdominal procedures of past decades, VMR avoids posterolateral rectal mobilisation and thereby minimizes the risk of postoperative constipation. Because of a perceived acceptable recurrence rate, good functional results and low mesh-related morbidity in the short to medium term, VMR has been popularized in the past decade. Laparoscopic or robotic-assisted VMR is now being progressively performed internationally and several articles and guidelines propose the procedure as the treatment of choice for rectal prolapse. In this article, an outline of the current status of laparoscopic and robotic ventral mesh rectopexy for the treatment of internal and external rectal prolapse is presented. | Jan J van Iersel Tim JC Paulides Paul M Verheijen John W Lumley Ivo AMJ Broeders Esther CJ Consten | 2016 | World Journal of Gastroenterology2016，22，21： | 20 |
| 12 | Role of receptor tyrosine kinases in gastric cancer: New targets for a selective therapy显示文摘受体酷氨酸家族 ases (RTK ) 象表皮的生长因素受体家庭那样包括增长和变形传播参予肿瘤形成的几步。几已知的 RTK 起来在是主要的胃的癌症调整了定制的治疗的目标。仅仅初步的数据然而,在使用上存在当前临床上可得到的药象在胃的癌症的背景的 trastuzumab, cetuximab, bevacizumab, gefitinib, erlotinib,和 imatinib 那样。现出症状之前的潜的数据建议他们的使用的一个潜在的好处,特别在有“常规”的抑制细胞的联合治疗。这评论象新途径和药一样在癌症治疗关于他们的使用总结当前的知识优化治疗成功。 | JC Becker C Müller-Tidow H Serve W Domschke T Pohle | 2006 | World Journal of Gastroenterology2006，12，21： | 19 |
| 13 | Climate Change’s Role in Disaster Risk Reduction’s Future:Beyond Vulnerability and Resilience显示文摘A seminal policy year for development and sustainability occurs in 2015 due to three parallel processes that seek long-term agreements for climate change, the Sustainable Development Goals, and disaster risk reduction.Little reason exists to separate them, since all three examine and aim to deal with many similar processes, including vulnerability and resilience. This article uses vulnerability and resilience to explore the intersections and overlaps amongst climate change, disaster risk reduction, and sustainability. Critiquing concepts such as 'return to normal'and 'double exposure'demonstrate how separating climate change from wider contexts is counterproductive. Climate change is one contributor to disaster risk and one creeping environmental change amongst many, and not necessarily the most prominent or fundamental contributor. Yet climate change has become politically important, yielding an opportunity to highlight and tackle the deep-rooted vulnerability processes that cause 'multiple exposure'to multiple threats. To enhance resilience processes that deal with the challenges, a prudent place for climate changewould be as a subset within disaster risk reduction. Climate change adaptation therefore becomes one of many processes within disaster risk reduction. In turn, disaster risk reduction should sit within development and sustainability to avoid isolation from topics wider than disaster risk. Integration of the topics in this way moves beyond expressions of vulnerability and resilience towards a vision of disaster risk reduction’s future that ends tribalism and separation in order to work together to achieve common goals for humanity. | Ilan Kelman JC Gaillard Jessica Mercer | 2015 | International Journal of Disaster Risk Science2015，6，1： | 19 |
| 14 | Awakening concentration of desflurane is decreased in patients with obstructive jaundice显示文摘 | Song JG Cao YF Yang LQ Yu WF Li Q Song JC Fu XY Fu Q | 2005 | 第二军医大学学报2005，26，8： | 15 |
| 15 | 假肿瘤性胰腺炎的CT表现显示文摘目的 提高对慢性假肿瘤性胰腺炎的影像学特征的认识。材料与方法 回顾性分析 12例经临床、病理诊断的假肿瘤性胰腺炎的特点。结果 12例均见胰腺实质肿块形成 ,大多为类圆形 ,直径为 2 .5~ 4cm ,边缘规则 ,肿块较均质。如肿块较大 ,则密度不均 ,中心坏死 ,边缘不规则。 8例肿块内有钙化。CT增强扫描肿块大多呈明显强化。 11例位于胰头部 ,1例位于胰体部。 7例B超呈低回声 ,5例为不均匀回声。结论 假肿瘤性胰腺炎与胰腺癌的鉴别极为困难 ,有时甚至是不可能的。但是结合临床过程 ,影像特征综合分析 ,可提高诊断率。 | 陈韵彬 Hoeffel JC 李铭山 | 2000 | 临床放射学杂志2000，19，11： | 14 |
| 16 | Blood pressure,prevalence of hypertension and hypertension related complications in Nigerian Africans:A review显示文摘To review studies on hypertension in Nigeria over the past five decades in terms of prevalence,awareness and treatment and complications.Following our search on Pubmed,African Journals Online and the World Health Organization Global cardiovascular infobase,1060 related references were identified out of which 43 were found to be relevant for this review.The overall prevalence of hypertension in Nigeria ranges from 8%-46.4% depending on the study target population,type of measurement and cut-off value used for defining hypertension.The prevalence is similar in men and women(7.9%-50.2% vs 3.5%-68.8%,respectively) and in the urban(8.1%-42.0%) and rural setting(13.5%-46.4%).The pooled prevalence increased from 8.6% from the only study during the period from 1970-1979 to 22.5%(2000-2011).Awareness,treatment and control of hypertension were generally low with attendant high burden of hypertension related complications.In order to improve outcomes of cardiovascular disease in Africans,public health education to improve awareness of hypertension is required.Further epidemiological studies on hypertension are required to adequately understand and characterize the impact of hypertension in society. | Okechukwu S Ogah Ikechi Okpechi Innocent I Chukwuonye Joshua O Akinyemi Basden JC Onwubere Ayodele O Falase Simon Stewart Karen Sliwa | 2012 | World Journal of Cardiology2012，4，12： | 13 |
| 17 | 在有类型 2 糖尿病的病人的 nephropathy 的管理。 | Critchley JA Zhao HL Tomlinson B Leung W Thomas GN Chan JC Cockram CS | 2002 | Chinese Medical Journal2002，，1： | 12 |
| 18 | Scavenger receptor BI: A multi-purpose player in cholesterol and steroid metabolism显示文摘Scavenger receptor class B type Ⅰ (SR-BI) is an important member of the scavenger receptor family of integral membrane glycoproteins. This review highlights studies in SR-BI knockout mice, which concern the role of SR-BI in cholesterol and steroid metabolism. SR-BI in hepatocytes is the sole molecule involved in selective uptake of cholesteryl esters from high-density lipoprotein (HDL). SR-BI plays a physiological role in binding and uptake of native apolipoprotein B (apoB)-containing lipoproteins by hepatocytes, which identif ies SR-BI as a multipurpose player in lipid uptake from the blood circulation into hepatocytes in mice. In adrenocortical cells, SR-BI mediates the selective uptake of HDL-cholesteryl esters, which is eff iciently coupled to the synthesis of glucocorticoids (i.e. corticosterone). SR-BI knockout mice suffer from adrenal glucocorticoid insuff iciency, which suggests that functional SR-BI protein is necessary for optimal adrenal steroidogenesis in mice. SR-BI in macrophages plays a dual role in cholesterol metabolism as it is able to take up cholesterol associated with HDL and apoBcontaining lipoproteins and can possibly facilitate cholesterol efflux to HDL. Absence of SR-BI is associated with thrombocytopenia and altered thrombosis susceptibility, which suggests a novel role for SR-BI in regulating platelet number and function in mice. Transgenic expression of cholesteryl ester transfer protein in humanized SR-BI knockout mice normalizes hepatic delivery of HDL-cholesteryl esters. However, other pathologies associated with SR-BI def iciency, i.e. increased atherosclerosis susceptibility, adrenal glucocorticoid insuffi ciency, and impaired platelet function are not normalized, which suggests an important role for SR-BI in cholesterol and steroid metabolism in man. In conclusion, generation of SR-BI knockout mice has signif icantly contributed to our knowledge of the physiological role of SR-BI. Studies using these mice have identif ied SR-BI as a multi-purpose player in cholesterol and steroid metabolism because it has distinct roles in reverse cholesterol transport, adrenal steroidogenesis, and platelet function. | Menno Hoekstra Theo JC Van Berkel Miranda Van Eck | 2010 | World Journal of Gastroenterology2010，16，47： | 11 |
| 19 | Treatment of diffuse intrinsic brainstem gliomas: failed approaches and future strategies显示文摘 | Frazier JL Lee J Thomale UW Noggle JC Cohen K J Jallo GI | 2009 | 中国神经肿瘤杂志2009，7，3： | 10 |
| 20 | Determination of global mean sea surface WHU2000 using multi-satellite altimetric data显示文摘In this study, the overall editing criteria for altimetric data are considered and the geophysical correction models is improved. The datum for various altimetric data is also unified and the method of a full-combined crossover adjustment for different altimetric tracks is used to improve the radial orbits of Geosat, ERS-1 and ERS-2 data. In addition, the method for determining mean sea surface (MSS) by using multi-altimetric data is developed. The data used to compute WHU2000 MSS include 7-year Topex/Poseidon data (cycles 11-249), 2-year Geosat ERM data (cycles 1-44), 5-year ERS2 data (cycles 1-52) and all ERS-1 168-day data. The WHU2000 MSS is determined with a grid resolution of 2’×2’ within the ± 82° latitude and its precision is better than 0.05 m. Comparing WHU 2000MSS with 3.75’×3.75’ CLS_SHOM98.2 MSS, 3’×3’ GFZ MSS95A and 3.75’×3.75’ OSU MSS95, as external checks, the corresponding standard deviation (STD) of their differences is 0.090 m, 0.211 m and 0.079 m respectively. | Jiang, WP Li, JC Wang, ZG | 2002 | Chinese Science Bulletin2002，47，19： | 9 |
您所在的机构暂未开通此部分的功能，请联系管理员