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| 1 | Is endoscopic ultrasound examination necessary in the management of esophageal cancer?显示文摘Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer(EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have improved from 5% to 20% since the 1970 s, the result of advances in diagnostic staging and treatment. As the most sensitive test for locoregional staging of EC, endoscopic ultrasound(EUS) influences the development of an optimal oncologic treatment plan for a significant minority of patients with early cancers, which appropriately balances the risks and benefits of surgery, chemotherapy and radiation. EUS is costly, and may not be available at all centers. Thus, the yield of EUS needs to be thoughtfully considered for each patient. Localized intramucosal cancers occasionally require endoscopic resection(ER) for histologic staging or treatment; EUS evaluation may detect suspicious lymph nodes prior to exposing the patient to the risks of ER. Although positron emission tomography(PET) has been increasingly utilized in staging EC, it may be unnecessary for clinical staging of early, localized EC and carries the risk of false-positive metastasis(over staging). In EC patients with evidence of advanced disease, EUS or PET may be used to define the radiotherapy field. Multimodality staging with EUS, crosssectional imaging and histopathologic analysis of ER, remains the standard-of-care in the evaluation of early esophageal cancers. Herein, published data regarding use of EUS for intramucosal, local, regional and metastatic esophageal cancers are reviewed. An algorithm to illustrate the current use of EUS at The University of Texas MD Anderson Cancer Center is presented. | Tomas DaVee Jaffer A Ajani Jeffrey H Lee | 2017 | World Journal of Gastroenterology2017，23，5： | 11 |
| 2 | Endoscopic management of esophageal cancer显示文摘Esophageal cancer(EC)generally consists of squamous cell carcinoma(which arise from squamous epithelium)and adenocarcinoma(which arise from columnar epithelium).Due to the increased recognition of risk factors associated with EC and the development of screening programs,there has been an increase in the diagnosis of early EC.Early EC is amenable to curative therapy by endoscopy,which can be performed by either endoscopic resection or endoscopic ablation.Endoscopic resection consists of either endoscopic mucosal resection(preferred in cases of adenocarcinoma)or endoscopic submucosal dissection(preferred in cases of squamous cell carcinoma).Endoscopic ablation can be performed by either radiofrequency ablation,cryotherapy,argon plasma coagulation or photodynamic therapy,amongst others.Endoscopy can also assist in the management of complications post-esophageal surgery,such as anastomotic leaks and perforations.Finally,there is a growing role for endoscopy to manage end-of-life palliative symptoms,especially dysphagia.The growing use of esophageal stents,debulking therapy and dilation can assist in improving a patient’s quality of life.In this review,we examine the multiple roles of endoscopy in the management of patients with EC. | Osman Ahmed Jaffer A Ajani Jeffrey H Lee | 2019 | World Journal of Gastrointestinal Oncology2019，11，10： | 6 |
| 3 | Blast-associated shock waves result in increased brain vascular leakage and elevated ROS levels in a rat model of traumatic brain injury显示文摘 | Kabu S Jaffer H Petro M | 2015 | PLoS One2015，10，01： | 1 |
| 4 | Advances in Stroke Therapy显示文摘 | Jaffer H Morris VB Stewart D | 2011 | Drug Deliv Transl Res2011，1，： | 1 |
| 5 | Conditions for efficient spin injection from a ferromagnetic metal into a semicon- ductor显示文摘 | FERT A JAFFERS H | 2001 | Phys Rev B2001，，18： | 1 |
| 6 | Asymmetric transport due to spin injection into a kondo alloy显示文摘 | MATTANA R GEORGE J M JAFFERS H | 2003 | Phys Rev Lett2003，90，16： | 1 |
| 7 | Advances in Stroke Therapy显示文摘 | JAFFER H MORRIS V B STEWART D | 2011 | Drug Deliv Transl Res2011，1，6： | 1 |
| 8 | Clinical features of mixed physiology of constriction and restriction: Echocardiographic characteristics and clinical outcome显示文摘 | Yamada H Tabata T Jaffer S J | 2007 | Eur J Echocardiogr2007，8，3： | 1 |
| 9 | Essential role for both CD86 and CD86 costimulation , but not CD40 interactions , in allergen-induced Th2 cytokine production from asthmatic bronchial tissue: role for αβ, but not γδ, T cells显示文摘 | Stanciu L Pandit A | 1999 | J Immunol1999，163，： | 1 |
| 10 | Adaptive Nonlinear Filtering for Tracking with Measurements of Uncertain Origin显示文摘 | BAR-SHALOM Y JAFFER h G | 1972 | Conference on Decision and Control1972，，11： | 1 |
| 11 | In vivo imaging of throm- bin activity in experimental thrombi with thrombin-sensitive near-infra- red molecular probe 显示文摘 | Jaffer F A Tung C H Gerszten R E | 2002 | Arterioscler Thromb Vasc Biol2002，22，11： | 1 |
| 12 | Gastric cancer:advances in ad- juvant and adjunct therapy 显示文摘 | Katsuhiko H Alexandria P Jaffer A | 2003 | Curr Treat Opt Oncol2003，4，5： | 1 |
| 13 | Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: correlation with pulmonary dose–volume histogram parameters显示文摘 | Hoon K Lee Ara A Vaporciyan James D Cox Susan L Tucker Joe B Putnam Jaffer A Ajani Zhongxing Liao Stephen G Swisher Jack A Roth W.Roy Smythe Garrett L Walsh Radhe Mohan Hui H Liu Deidre Mooring Ritsuko Komaki | 2003 | International Journal of Radiation Oncology Biology Physics2003，，5： | 1 |
| 14 | A multi-scale dynamic two-dimensional heterogeneous model for catalytic steam methane reforming reactors显示文摘 | Ghouse Jaffer H Adams Thomas A Ⅱ | 2013 | International Journal of Hydrogen Energy2013，38，： | 1 |
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