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162篇 您的检索式:作者名="JOERN"
    题名 作者 年代 出处 被引量
1组织工程化人工神经修复长段神经缺损实验的初步报告显示文摘目的 研究组织工程化人工神经修复大鼠 2 .5cm长坐骨神经缺损的效果。方法 90只 2个月月龄的Lewis 1W雌性大鼠 ,按手术先后顺序随机分成 3个神经移植组 ,每组 3 0只。A组 :用种植同源雪旺细胞并具有内部支架结构的胶原神经管桥接 ,即组织工程化人工神经组。B组 :用无雪旺细胞但具有内部支架结构的胶原神经管桥接 ,即对照组。C组 :自体神经移植组。术后 6个月 ,进行神经电生理监测 ,神经肌肉组织学观察 ;用S 10 0和神经微丝蛋白免疫组化染色后 ,行轴突计数等检测。结果 完成对 2 1只大鼠 (每组 7只 )的实验评估。从A组和C组的胫前肌中均能诱发出波幅明显的神经肌肉复合动作电位 (CMAP) ,再生轴突已通过移植段神经全长 ,远端肌肉轻度萎缩。B组中则没有或仅记录到波幅很低的CMAP ,移植神经远端结缔纤维组织增生 ,再生轴突罕见 ,所支配肌肉明显萎缩。结论 组织工程化人工神经可用来修复大鼠长段神经缺损。沈尊理 Berger Alfred Hierner Robert Lohmeyer Joern Allmeling Christina Walter F.Gerhard 2001中华手外科杂志2001,17,2:22
2不同细胞分离制备方法下异丙酚对中性粒细胞呼吸爆发作用的影响显示文摘目的 在两种中性粒细胞(PMNL)分离制备方法下观察异丙酚对PMNL呼吸爆发活性的作用,以探讨不同PMNL制备方法对其呼吸爆发作用测量的影响。方法 将治疗剂量和10倍治疗剂量的异丙酚(6μg·mL-1,60μg·mL-1)与PMNL进行孵育,分别以大肠杆菌(E.coli),12-肉豆蔻酰-13-乙酰佛波酸(PMA)或N-甲酞甲硫酰亮氨酚苯丙氨酸(FMLP)诱导产生呼吸爆发作用。所有标本均分为两份,分别经Ficoll分离法制备后使用,或以全血法直接测定。以流式细胞仪测定发生呼吸爆发作用而产生过氧化物的PMNL百分数。结果 在Ficoll分离组中,与对照组比较,6μg·mL-1和60μg·mL-1异丙酚显著抑制FMLP诱导的PMNL呼吸爆发作用(P<0.01),60μg·mL-1异丙酚显著抑制PMA诱导的PMNL呼吸爆发作用(P<0.01);全血法组中60μg·mL-1异丙酚对FMLP和 E.coli诱导的 PMNL呼吸爆发活性有显著抑制作用(P<0.05)。采用Ficoll法与全血法制备的PMNL比较,测定的异丙酚对呼吸爆发(以PMA和FMLP诱导)的抑制作用存在显著性差异(P<0.01)。结论 治疗剂量和10倍治疗剂量的异丙酚对于中性粒细胞的呼吸爆发活性有抑制作用,以流式细胞仪法测定PMN的呼吸爆发作用与PMN的分离制备方法有关。赵晶 罗爱伦 Joern Heine Siegfred Piepenbrock 2002中华麻醉学杂志2002,22,8:11
3组织工程化人工神经实验研究显示文摘目的 研究组织工程化人工神经修复大鼠2.5cm长坐骨神经缺损的效果。方法 21只2月龄Lewis lw雌性大鼠随机分成三个神经移植组,每组7只。A组:种植同源雪旺细胞并具有内部支架结构的胶原神经管,即组织工程化人工神经。B组:无雪旺细胞但具有内部支架结构的胶原神经管。C组:自体神经移植组。术后六个月,进行系列神经电生理监测,神经肌肉组织学观察,S-100和神经微丝蛋白(Neurofilament)免疫组化染色,轴突计数等检查。结果 在A组和C组移植神经上均能诱发出波幅明显的神经肌肉复合动作电位(CMAP),再生轴突已通过移植神经全长,远端肌肉轻度萎缩。而B组中没有或仅记录到极小波幅的CMAP,移植神经远端结缔纤维组织增生,再生轴突罕见,所支配肌肉明显萎缩。结论 初步结果显示:组织工程化人工神经可用来修复大鼠长段神经缺损。沈尊理 BERGER Alfred HIERNER Robert LOHMEYER Joern ALLMELING Christina WALTER F.Gerhard 2000中国创伤骨科杂志2000,2,4:4
4Integrated Assessment of Natural Hazards, Including Climate Change’s Influences, for Cultural Heritage Sites: The Case of the Historic Centre of Rethymno in Greece显示文摘Within the framework of disaster risk management, this article proposes an interdisciplinary method for the analysis of multiple natural hazards, including climate change’s influences, in the context of cultural heritage. A taxonomy of natural hazards applicable to cultural heritage was developed based on the existing theoretical and conceptual frameworks. Sudden-onset hazards, such as earthquakes and floods, and slow-onset hazards, such as wetting–drying cycles and biological contamination, were incorporated into the hazard assessment procedure. Future alteration of conditions due to climate change, such as change in heat waves’ duration, was also taken into account. The proposed hazard assessment framework was applied to the case of the Historic Centre of Rethymno, a city on the northern coast of the island of Crete in Greece,to identify, analyze, and prioritize the hazards that have the potential to cause damage to the center’s historic structures. The assessment procedure includes climate model projections, GIS spatial modeling and mapping, and finally a hazard analysis matrix to enable the sharing of a better understanding of multiple hazards with the stakeholders.The results can facilitate decision making by providing the vulnerability and risk analysis with the nature and spatial distribution of the significant hazards within the study area and its setting.Mohammad Ravankhah Rosmarie de Wit Athanasios V.Argyriou Angelos Chliaoutakis Maria Joao Revez Joern Birkmann Maja Zuvela-Aloise Apostolos Sarris Anastasia Tzigounaki Kostas Giapitsoglou 2019International Journal of Disaster Risk Science2019,10,3:3
5Socioecological drivers facilitating biodiversity conservation in traditional farming landscapes显示文摘Traditional farming landscapes have evolved as tightly coupled socioecological systems that support high biodiversity.However,land-use change severely threatens the high biodiversity of these landscapes.Navigating nature conservation in such landscapes requires a thorough understanding of the key drivers underpinning biodiversity.Through empirical research on mammals,birds,butterflies,and plants in a traditional cultural landscape in Romania,we revealed seven hypothesized drivers facilitating biodiversity conservation.Similar proportions of three main land-use types support the landscape species pool,most likely through habitat connectivity and frequent spillover between land-use types.Landscape complementation and supplementation provide additional habitat for species outside their core habitats.Gradients of woody vegetation cover and gradients in land-cover heterogeneity provide mosaic landscapes with wide ranges of resources.Traditional land-use practices underpin landscape heterogeneity,traditional land-use elements such as wood pastures,and human-carnivore coexistence.Top-down predator control may limit herbivore populations.Lastly,cultural ties between humans and nature have a central influence on people’s values and sustainable use of natural resources.Conservation approaches should aim to maintain or restore these socioecological drivers by targeting the heterogeneous character of the forest-farmland mosaic at large scales through'broad and shallow'conservation measures.These large-scale measures should be complemented with'deep and narrow'conservation measures addressing specific land-use types,threats,or species.In both cases,conservation measures should integrate the entire socioecological system,by recognizing and strengthening important links between people and the environment.Ine Dorresteijn Jacqueline Loos Jan Hanspach Joern Fischer 2015Ecosystem Health and Sustainability2015,1,9:3
6Stereotactic radiotherapy of primary liver cancer and hepatic metastases显示文摘Joern Wulf Matthias Guckenberger Ulrich Haedinger Ulrich Oppitz Gerd Mueller Kurt Baier Michael Flentje 2006Acta Oncologica2006,,7:2
7Grasshoppers (Orthoptera: Acrididae) select vegetation patches in local-scale responses to foliar nitrogen but not phosphorus in native grassland显示文摘象氮(N) 和磷(P) 那样的关键元素经常相对在他们上喂的草食动物的营养的需要正在限制。当 N 经常在自然陆上的生态系统限制昆虫草食动物时, P 的效果糟糕在这个领域里被学习,尽管从生态的 stoichiometry 文学的引人注目的假设预言它的重要性。我们评估小规模的空间分布,和 herbivory 由,在在 tallgrass 在 foliar-N 和 -P 变化的附近的阴谋之中的蚂蚱大草原。蚂蚱密度是 67% 在使肥沃 N 的阴谋更大但是没从 P 化肥检测效果到蚂蚱密度。主导的草 Andropogon gerardii 的叶损坏是 32% 在使肥沃 N 的阴谋,而是对 foliar-P 的没有反应更大被检测。普通非禾本草本植物的草食动物损坏,秋麒麟草属植物(Solidago missouriensis ) ,没被化肥处理强烈连接,尽管有增加的叶,当没有 P 被使用时,在 N 化肥损坏处理(重要 N 渠瑡癩?牧獡汳湡Viviana Loaiza Jayne L. Jonas Anthony Joern 2011Insect Science2011,18,5:2
8人文主义与自然:对一种复杂关系的反思显示文摘探讨人文主义与自然的关系问题,关键在于如何处理文化与自然的关系。由于对人类文化属性的强调,人文主义把人性视为文化的产物,并将其与自然置于强烈的对比和对立关系之中。此种人文主义观念对于人类正在遭遇的生态危机有一定关系。但是人文主义并不因此而应该受到完全否定。问题的出路不在于人类文化的重新自然化,也不在于自然的文化化,而在于寻求一种将人性看作自然与文化之合成的新人文主义。借此,人文主义能够将其对自然的传统理解作为人类文化成就的潜能保持下来。同时,它还可以获得一种新的跨文化普遍性,使人类能够在保持文化差异性和多样性的前提下分享共同人性,重新认识人类的本质。约恩·吕森(Joern Rüsen) 谢进东(译) 2007古代文明2007,1,2:2
9The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes显示文摘Intestinal Foxp3+regulatory T cell(Treg)subsets are crucial players in tolerance to microbiota-derived and food-borne antigens,and compelling evidence suggests that the intestinal microbiota modulates their generation,functional specialization,and maintenance.Selected bacterial species and microbiota-derived metabolites,such as short-chain fatty acids(SCFAs),have been reported to promote Treg homeostasis in the intestinal lamina propria.Furthermore,gut-draining mesenteric lymph nodes(mLNs)are particularly efficient sites for the generation of peripherally induced Tregs(pTregs).Despite this knowledge,the direct role of the microbiota and their metabolites in the early stages of pTreg induction within mLNs is not fully elucidated.Here,using an adoptive transfer-based pTreg induction system,we demonstrate that neither transfer of a dysbiotic microbiota nor dietary SCFA supplementation modulated the pTreg induction capacity of mLNs.Even mice housed under germ-free(GF)conditions displayed equivalent pTreg induction within mLNs.Further molecular characterization of these de novo induced pTregs from mLNs by dissection of their transcriptomes and accessible chromatin regions revealed that the microbiota indeed has a limited impact and does not contribute to the initialization of the Treg-specific epigenetic landscape.Overall,our data suggest that the microbiota is dispensable for the early stages of pTreg induction within mLNs.Carolin Wiechers Mangge Zou Eric Galvez Michael Beckstette Maria Ebel Till Strowig Jochen Huehn Joern Pezoldt 2021Cellular & Molecular Immunology2021,18,5:2
10Phosphorus loss in agricultural drainage: Historical perspective and current research显示文摘Sims J T Simard R R Joern B C 1998Journal of Environmental Quality1998,27,:1
11Phosphorus Indices: Why We Need to Take Stock of How We Are Doing显示文摘Sharpley Andrew Beegle Doug Bolster Carl Good Laura Joern Brad Ketterings Quirine Lory John Mikkelsen Rob Osmond Deanna Vadas Peter 2012Journal of Environmental Quality2012,,6:1
12Lead- acid batteries in micro -hybrid vehicles 显示文摘JOERN A EBERHARD M SEPEHR H 2011J Power Sources2011,,196:1
13显示文摘Joern JM 2003Methods Mol Biol2003,231,:1
14Phytase, high - available - phosphorus corn, and storage effects on phosphorus levels in pig excreta显示文摘Baxter C A Joern B C Ragland D 2003J Environ Qual2003,32,:1
15Phosphorus Loss in Agricultural Drainage: Historical Perspective and Current Research显示文摘Sims J T Simard R R Joern B C 1998Journal environmental quality1998,27,2:1
16Influence of phosphorus and potassium on alfalfa yield and yield components 显示文摘W K Berg S M Cunningham S M Brouder B C Joern K D Johnson J Santini J J Volenec 2005Crop Science2005,45,1:1
17圈养猞猁多雄交配雄性的成功繁殖(英文)显示文摘研究了笼养猞猁多雄交配的结果以及雄性的成功繁殖。雄兽与发情雌兽随机配对,其繁殖成功(所产生的后代数量)不取决于与雌兽的交配顺序、交配次数与持续时间、遗传关系或雄兽的行为特征,但似乎取决于精子质量,特别是取决于形态正常精子的百分率。繁殖成功的雄兽比其竞争对手具有更多的形态正常的精子,似乎更能成功地诱发交配雌兽的排卵。证实了4窝(占总窝数的20%)幼兽的双重父亲身份。在所有情形下, 2雄1雌的交配间隔为24h 。Sergey NAIDENKO Mariya EROFEEVA Frank GOERITZ Katrin NEUBAUER Joerns FICKEL Katarina JEWGENOW 2007动物学报2007,53,3:1
18Injuries among competitive snowboanters at the national elite level显示文摘Joern T Roald B 2005American Journal of Sports Medicine2005,33,3:1
19The two faces of market support—How deployment policies affect technological exploration and exploitation in the solar photovoltaic industry显示文摘Joern Hoppmann Michael Peters Malte Schneider Volker H. Hoffmann 2013Research Policy2013,,:1
20Supplemental nitrogen effects on al- falfa regrowth and nitrogen mobilization by corn roots 显示文摘Barber L D Joern B C 1996Crop Science1996,36,:1
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