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| 1 | Safety of hepatectomy for elderly patients with hepatocellular carcinoma显示文摘The number of elderly patients with hepatocellular carcinoma(HCC) has been increasing.Characteristics of elderly HCC patients are a higher proportion of females,a lower rate of positive hepatitis B surface antigen,and a higher rate of positive hepatitis C antibodies.Careful patient selection is vital for performing hepatectomy safely in elderly HCC patients.Treatment strategy should be decided by not only considering tumor stage and hepatic functional reserve,but also physiological status,including comorbid disease.Various assessment tools have been applied to predict the risk of hepatectomy.The reported mortality and morbidity rates after hepatectomy in elderly HCC patients ranged from 0% to 42.9% and from 9% to 51%,respectively.Overall survival rate after hepatectomy in elderly HCC patients at 5 years ranged from 26% to 75.9%.Both short-term and long-term results after hepatectomy for strictly selected elderly HCC patients are almost the same as those for younger patients.However,considering physiological characteristics and the high prevalence of comorbid disease in elderly patients,it is important to assess patients more meticulously and to select them strictly if scheduled to undergo major hepatectomy. | Koichi Oishi Toshiyuki Itamoto Toshihiko Kohashi Yasuhiro Matsugu Hideki Nakahara Mikiya Kitamoto | 2014 | World Journal of Gastroenterology2014，20，41： | 8 |
| 2 | Utility of single-incision totally extraperitoneal inguinal hernia repair with intraperitoneal inspection显示文摘AIM To study the utility of single-incision totally extraperitoneal inguinal hernia repair with intraperitoneal inspection.METHODS A 2 cm transverse skin incision was made in the umbilicus, extending to the intraperitoneal cavity. Carbon dioxide was insufflated followed by insertion of laparoscope to observe the intraperitoneal cavity. The type of hernia was diagnosed and whether there was the presence of intestinal incarceration was confirmed. When an intestinal incarceration in the hernia sac was found, the forceps were inserted through the incision site and the intestine was returned to the intraperitoneal cavity without increasing the number of trocars. Once the peritoneum was closed, totally extraperitoneal inguinal hernia repair was performed, and finally, intraperitoneal observation was performed to reconfirm the repair.RESULTS Of the 75 hernias treated, 58 were on one side, 17 were on both sides, and 10 were recurrences. The respective median operation times for these 3 groups of patients were 100 min(range, 66 to 168), 136 min(range, 114 to 165), and 125 min(range, 108 to 156), with median bleeding amounts of 5 g(range, 1 to 26), 3 g(range, 1 to 52), and 5 g(range, 1 to 26), respectively. Intraperitoneal observation showed hernia on the opposite side in 2 cases, intestinal incarceration in 3 cases, omental adhesion into the hernia sac in 2 cases, severe postoperative intraperitoneal adhesions in 2 cases, and bladder protrusion in 1 case. There was only 1 case of recurrence.CONCLUSION Single-incision totally extraperitoneal inguinal hernia repair with intraperitoneal inspection makes hernia repairs safer and reducing postoperative complications. The technique also has excellent cosmetic outcomes. | Masateru Yamamoto Takashi Urushihara Toshiyuki Itamoto | 2017 | World Journal of Gastrointestinal Surgery2017，9，12： | 6 |
| 3 | Primary biliary cholangitis metachronously complicated with combined hepatocellular carcinoma-cholangiocellular carcinoma and hepatocellular carcinoma显示文摘Primary biliary cholangitis(PBC) is a progressive cholestatic liver disease characterized by the presence of highly specific antimitochondrial antibodies, portal inflammation and lymphocyte-dominated destruction of the intrahepatic bile ducts, which leads to cirrhosis. While its pathogenesis remains unclear, PBC that shows histological progression to fibrosis carries a high risk of carcinogenesis; the same is true of viral liver diseases. In patients with PBC, the development of hepatocellular carcinoma(HCC) is rare; the development of combined hepatocellular carcinoma and cholangiocellular carcinoma(c HCC-CCC) is extraordinary. Herein, we report a rare case of PBC metachronously complicated by c HCC-CCC and HCC, which, to the best of our knowledge, has never been reported. We present a case report of a 74-year-old Japanese woman who was diagnosed as PBC in her 40's by using blood tests and was admitted to our department for further management of an asymptomatic liver mass. She had a tumor of 15 mm in size in segment 8 of the liver and underwent a partial resection of the liver. Subsequent pathological findings resulted in the diagnosis of c HCC-CCC, arising from stage 3 PBC. One year after the initial hepatectomy, a second tumor of 10 mm in diameter was found in segment 5 of the liver; a partial resection of the liver was performed. Subsequent pathological findings led to HCC diagnosis. The component of HCC in the initial tumor displayed a trabecular growth pattern while the second HCC showed a pseudoglandular growth pattern, suggesting that metachronous tumors that arise from PBC are multicentric. | Ryuta Ide Akihiko Oshita Takashi Nishisaka Hideki Nakahara Shiomi Aimitsu Toshiyuki Itamoto | 2017 | World Journal of Hepatology2017，9，36： | 2 |
| 4 | Biliary Complications after Duct-to-duct Biliary Reconstruction in Living-donor Liver Transplantation: Causes and Treatment显示文摘 | Hirotaka Tashiro Toshiyuki Itamoto Tamito Sasaki Hideki Ohdan Yasuhiro Fudaba Hironobu Amano Saburo Fukuda Hideki Nakahara Kohei Ishiyama Akihiko Ohshita Toshihiko Kohashi Hiroshi Mitsuta Kazuaki Chayama Toshimasa Asahara | 2007 | World Journal of Surgery2007，，11： | 2 |
| 5 | Impact of Pegylated Interferon Therapy on Outcomes of Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma After Curative Hepatic Resection显示文摘 | Yoshisato Tanimoto MD Hirotaka Tashiro MD Hiroshi Aikata MD Hironobu Amano MD Akihiko Oshita MD Tsuyoshi Kobayashi MD Shintaro Kuroda MD Hirofumi Tazawa MD Shoichi Takahashi MD Toshiyuki Itamoto MD Kazuaki Chayama MD Hideki Ohdan MD | 2012 | Annals of Surgical Oncology2012，，2： | 2 |
| 6 | Percutaneous microwave coagulation therapy for primary or recurrent hepatocellular carcinoma: long-term results 显示文摘 | Itamoto T Katayama K Fukuda S | 2001 | Hepatogastroenterology2001，48，41： | 1 |
| 7 | Effects of an androgenic growth promoter 17β-trenbolone on masculinization of Mosquitofish (Gambusia affinis affinis)显示文摘 | Sone K Hinago M Itamoto M | 2005 | Gen Comp Endocrinol2005，143，： | 1 |
| 8 | Evaluation of the hemodynamic impact of continuous renal replacement therapy in healthy dogs 显示文摘 | Shimokawa-Miyama T Itamoto K Yoshioka C | 2010 | J Vet Med Sei2010，72，4： | 1 |
| 9 | ]'IS score as a predictor of survival after hepatectomy for hepatocellular carcinoma显示文摘 | Luo KZ Itamoto T Amano H Comparative study of the Japan Integrated Stage (JIS) and modified | 2008 | J Gastroenterol2008，43，5： | 1 |
| 10 | Percutaneous microwave coagulation therapy for primary or recurrent hepatocellular carcinoma:long-term results显示文摘 | Itamoto T Katayama K Fukuda S | 2001 | Hepatogastroenterology2001，48，： | 1 |
| 11 | Related Articles,Links Indications of partial hepatectomy for transplantable hepatocellular carcinoma with compensated cirrhosis显示文摘 | Itamoto T Nakahara H Tashiro H | 2005 | Am J Surg2005，189，2： | 1 |
| 12 | Repeat hepatectomy for recurrent hepatocellular carcinoma 显示文摘 | Itamoto T Nakahara H Amano H | 2007 | Surgery2007，141，5： | 1 |
| 13 | Repeat hepatectomy for recurrent hepatocellular carcinoma显示文摘 | Itamoto T Nakahara H Amano H | 2007 | Surgery2007，141，5： | 1 |
| 14 | Ef- fects of an androgenic growth promoter 1713-trenbolone on masculinization of Mosquitofish (Gambusia aff:nis) 显示文摘 | Kiyoaki Sone Megumi Hinago Misaki Itamoto | 2005 | General and Comparative Endocrinology2005，143，： | 1 |
| 15 | Perioperative Blood Transfusion as a Prognostic Indicator in Patients with Hepatocellular Carcinoma显示文摘 | Toshimasa Asahara Kouji Katayama Toshiyuki Itamoto Masatsugu Yano Hiroshi Hino Yuzo Okamoto Hideki Nakahara Kiyohiko Dohi Katsufumi Moriwaki Osafumi Yuge | 1999 | World Journal of Surgery1999，，7： | 1 |
| 16 | Radiofrequency-assisted partial splenectomy with a new and simple device 显示文摘 | Itamoto T Fukuda S Tashiro H | 2006 | Am J Surg2006，192，2： | 1 |
| 17 | Gasless laparoscopic hepatic resection for cirrhotic patients with solid liver tumors 显示文摘 | Itamoto T Katayama k Miura Y | 2002 | Surg Laparosc Endosc Percutan Tech2002，12，5： | 1 |
| 18 | Isolated caudate lobectomy by anterior approach for hepatocellular carcinoma originating in the paracaval portion of the caudate lobe显示文摘 | Toshimasa Asahara Kiyohiko Dohi Hiroshi Hino Hideki Nakahara Kouji Katayama Toshiyuki Itamoto Eiji Ono Katsufumi Moriwaki Osafumi Yuge Toshio Nakanishi Mikiya Kitamoto | 1998 | Journal of Hepato - Biliary - Pancreatic Surgery1998，，4： | 1 |
| 19 | Study on a new tool-dynamometer of piezoelectric type显示文摘 | YAMAMOTO A MAEDA Y ITAMOTO S | 1972 | Journal of the Japan Society of Precision Engineering1972，38，7： | 1 |
| 20 | Perioperative management of benign hepatic tumors in patients with glycogen storage disease type Ia显示文摘 | Akihiko Oshita Toshiyuki Itamoto Hironobu Amano Hideki Ohdan Hirotaka Tashiro Toshimasa Asahara | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，2： | 1 |
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