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| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018,26,12: | 29 |
| 2 | Involvement and therapeutic implications of airway epithelial barrier dysfunction in type 2 inflammation of asthma显示文摘Type 2 inflammation is a complex immune response and primary mechanism for several common allergic diseases including allergic rhinitis,allergic asthma,atopic dermatitis,and chronic rhinosinusitis with nasal polyps.It is the predominant type of immune response against helminths to prevent their tissue infiltration and induce their expulsion.Recent studies suggest that epithelial barrier dysfunction contributes to the development of type 2 inflammation in asthma,which may partly explain the increasing prevalence of asthma in China and around the globe.The epithelial barrier hypothesis has recently been proposed and has received great interest from the scientific community.The development of leaky epithelial barriers leads to microbial dysbiosis and the translocation of bacteria to inter-and sub-epithelial areas and the development of epithelial tissue inflammation.Accordingly,preventing the impairment and promoting the restoration of a deteriorated airway epithelial barrier represents a promising strategy for the treatment of asthma.This review introduces the interaction between type 2 inflammation and the airway epithelial barrier in asthma,the structure and molecular composition of the airway epithelial barrier,and the assessment of epithelial barrier integrity.The role of airway epithelial barrier disruption in the pathogenesis of asthma will be discussed.In addition,the possible mechanisms underlying the airway epithelial barrier dysfunction induced by allergens and environmental pollutants,and current treatments to restore the airway epithelial barrier are reviewed. | Xiang Dong Mei Ding Jinjin Zhang Ismail Ogülür Yagiz Pat Mübeccel Akdis Yadong Gao Cezmi A.Akdis | 2022 | Chinese Medical Journal2022,,5: | 4 |
| 3 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013,3,9: | 3 |
| 4 | Expression of NF-кB in prostate cancer lymph node metastases显示文摘 | Ismail Ha Lessard L Mes-Masson AM | 2004 | Prostate2004,58,3: | 1 |
| 5 | Photophysics and dynamics of coumarin laser dyes and their analytical implications显示文摘 | M S A Abdel-Mottaleb M S Antonious M M Abo Ali L F M Ismail B A El-Sayed A M K Sherief | 1992 | Proceedings of the Indian Academy of Sciences - Chemical Sciences1992,,2: | 1 |
| 6 | Characterizing the Saltol quantitative trait locus for salinity tolerance in rice 显示文摘 | Thomson M J Ocampo M Egdane J Rahman M A Sajise A G Adorada D L Tumimbang-Raiz E Blumwald E Seraj Z I Singh R K Gregorio G B Ismail A M | 2010 | Rice2010,3,2: | 1 |
| 7 | Thermal characterization of Al2O3 and ZnO reinforced silicone rubber as thermal pads for heat dissipation purposes 显示文摘 | Sim L C Ramanan S R Ismail H | 2005 | Thermochimia Acta2005,430,12: | 1 |
| 8 | Rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry显示文摘 | MAN C N GAM L H ISMAIL S | 2006 | Journal of Chromatography B2006,844,: | 1 |
| 9 | 显示文摘 | Ismail A F David L I B | 2001 | J Membr Sci2001,193,1: | 1 |
| 10 | Thermal characterization of Al2O3 and ZnO reinforced silicone rubber as thermal pads for heat dissipation purposes显示文摘 | SIM L C RAMANAN S R ISMAIL H | 2005 | Thermochimia Acta2005,430,12: | 1 |
| 11 | Thermal characterization of A1203 and ZnO reinforced silicone rubber as thermal pads for heat dissipation purposes 显示文摘 | Sim L C Ramanan S R Ismail H | 2005 | ThermochimicaActa2005,430,12: | 1 |
| 12 | Type 2 diabetes mellitus patients with poor glycaemic control have lower quality of life scores asmeasured by the Short Form-36 显示文摘 | Kamarul Imran Ismail A Naing L | 2010 | Singapore Med J2010,51,2: | 1 |
| 13 | Expression of NF-κB in prostate cancer lymph node metastases显示文摘 | Ismail HA Lessard L Mes-Masson AM | | 0,,03: | 1 |
| 14 | The Impact of Brain Drain in Developing Countries显示文摘 | Ngoma A L Ismail N W | 2013 | South African Journal of Economics2013,,2: | 1 |
| 15 | Expression of NFkB in prostate cancer lymph node metastases 显示文摘 | Ismail H A Lessard L Mes-Masson A M | 2004 | Prostate2004,58,3: | 1 |
| 16 | Effect of a silane coupling agent on the properties of white rice husk ash-polypropylene-natural rubber composites显示文摘 | Ismail H Mega L Khalil HPS A | 2001 | Polymer International2001,50,5: | 1 |
| 17 | Affordable,entropy-consistent Euler flux functions Ⅱ:Entropy production at shocks显示文摘 | Ismail F Roe P L | | 0,,01: | 1 |
| 18 | A mobile robot path plan- ning using genetic algorithm in static environment 显示文摘 | Ismail A L T Sheta A Al-Weshah M | 2008 | Journal of Computer Science2008,4,4: | 1 |
| 19 | Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface 显示文摘 | Vaishnava S Behrendt C L Ismail A S et d | 2008 | Proc Natl Acad Sci U S A2008,105,20: | 1 |
| 20 | Design techniques for improving intrinsic accuracy of resistor string DACs显示文摘 | Shi C L Wilson J Ismail M | 2001 | Circ and Syst2001,1,5: | 1 |