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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Increased mean platelet volume associated with extent of slow coronary flow显示文摘 | ISIK T AYHAN E UYAREL H | 2012 | Cardiol J2012，19，4： | 1 |
| 3 | Relation of red cell distribution width with presence and severity of coronary artery ectasia显示文摘 | Isik T Kurt M Ayhan E | 2012 | Clin Appl Thromb Hemost2012，18，5： | 1 |
| 4 | Biological treatment of acid dyeing waste water using a sequential anaerobic/aerobic reactor sys- tem显示文摘 | ISIK M SPONZA D T | 2006 | Enzyme and Microbial Technology2006，38，7： | 1 |
| 5 | Relation of red cell distribution width with presence and severity of coronary artery ectasia显示文摘 | Isik T Kurt M Ayhan E | 2012 | Clin Appl Thromb Hemost2012，18，5： | 1 |
| 6 | Relation of red cell distri- bution width with presence and severity of coronary ar- tery ectasia 显示文摘 | Isik T Kurt M Ayhan E | 2012 | Clin Appl Thromb Hemost2012，18，5： | 1 |
| 7 | Decolorization of azo dyes under batch anaerobic and sequential anaerobic/aerobic conditions显示文摘 | Isik M Sponza D T | 2004 | Environ Sci Health Past A2004，39，4： | 1 |
| 8 | Bone marker levels in gingival crevicular fluid during orthodontic intrusive tooth movement:a preliminary study显示文摘 | Isik F Sayinsu K Arun T | 2005 | J Contemp Dent Pract2005，6，2： | 1 |
| 9 | The impact of admission red cell distribution width on the development of poor myocardial perfusion after primary percutaneous intervention显示文摘 | Isik T Kurt M Ayhan E | 2012 | Atherosclerosis2012，224，1： | 1 |
| 10 | Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease显示文摘 | Ulusoy GK Celik T Kayir H Gürsoy M Isik AT Uzbay TI | 2011 | Brain Res Bull2011，85，6： | 1 |
| 11 | Increased mean platelet volume associated with extent ofslow coronary flow显示文摘 | ISIK T AHAN E UYAREL H | 2012 | Cardiol J2012，19，4： | 1 |
| 12 | Relation of red cell distribu- tion width with the presence, severity, and complexity o{ coronary artery disease显示文摘 | Isik T Uyarel H Tanboga I H | 2012 | Coron Artery Dis2012，23，1： | 1 |
| 13 | Sagittal airway dimensions following maxillary protraction: a pilot study 显示文摘 | Sayinsu K Isik F Arun T | 2006 | Eur J Orthod2006，28，2： | 1 |
| 14 | Relation of red cell distribution width with the presence, severity, and complexity of coronary artery disease 显示文摘 | ISIK T UYAREL H TANBOGA I H | 2012 | Coron Artery Dis2012，23，1： | 1 |
| 15 | Relationship between red cell distri- bution width and stroke in patients with stable chronic heart failure: a propensity score matching analysis显示文摘 | Kaya A Isik T Kaya Y | 2013 | Clinical and Applied Throm- bosis/Hemostasis2013，1，10： | 1 |
| 16 | Severe hyponatremia due to escitalopram treatment in an elderly adult with Alzheimer' s disease显示文摘 | Pinar M D Isik A T | 2014 | J Am Geriat Society2014，62，12： | 1 |
| 17 | Increased mean platelet volume associated with extent of slow coronary flow 显示文摘 | ISIK T AYHAN E UYAREL H | 2012 | Cardiol J2012，19，4： | 1 |
| 18 | Comparison of transthoracic and transesophageal 2dimensional speckle tracking echocardiography显示文摘 | Kurt M Tanboga IH Isik T | 2012 | J Cardiothorac Vasc Anesth2012，26，1： | 1 |
| 19 | Precursor B cell lymphoblastic lymphoma presenting as a solitary bone tumor:a case report and review of the literature显示文摘 | Isik K Tayfur T Aslihan G | 2010 | Int J Hemat2010，12，： | 1 |
| 20 | Substrate romoval kinetics in an upflow an- aerobic sludge blanket reactor decolorising simulated textile wastewater显示文摘 | Isik M Sponza D T | 2005 | Process Biochemistry2005，40，34： | 1 |
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