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4篇 您的检索式:作者名="Irene Modesto"
    题名 作者 年代 出处 被引量
1Methodology for high-quality studies on course and prognosis of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBDs) are characterized by a chronic course with an alternation of relapses and remissions.Questions about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management decisions.Correct selection of the patients is the basis for good methodological studies on the course of IBD.A great proportion of data on the course of IBD is derived from a limited number of cohort studies.Studies help to define the endpoints for clinical trials and to identify subsets of patients in whom the prognosis of the disease can be stratified according to clinical features.Specific scientific requirements for high-quality studies on prognosis are the following:use of inception cohort,description of referral patterns,completeness of follow-up,objective outcome criteria,blind outcome assessment,adjustment for extraneous prognostic factors and statistical issues.We analyzed each of these requirements in studies on IBDs.To date,prospective and populationbased cohort studies are the standard for an unbiased assessment of prognosis.A better knowledge of the course of disease of chronic disorders ideally requires:(1) data from population-based studies,to avoid selection bias from referral centers in which patients with a more severe disease are usually treated;(2) inclusion of patients seen at the onset of the disease excluding misdiagnosed cases;and(3) follow-up from the onset of the disease to the end without dropouts.Irene Modesto Giovanni Perricone Ambrogio Orlando Mario Cottone 2012World Journal of Gastroenterology2012,18,29:7
2Is 5-ASA Still the Treatment of Choice for Ulcerative Colitis?显示文摘Mario Cottone Sara Renna Irene Modesto Ambrogio Orlando 2011Current Drug Targets2011,,10:2
3The Role of Portal Vein Thrombosis in the Clinical Course of Inflammatory Bowel Diseases: Report on Three Cases and Review of the Literature显示文摘Emanuele Sinagra Emma Aragona Claudia Romano Simonetta Maisano Ambrogio Orlando Roberto Virdone Lorenzo Tesè Irene Modesto Valeria Criscuoli Mario Cottone Paolo Gionchetti 2012<journal-title>Gastroenterology Research and Practice2012,,:1
4Mesalazine for the treatment of inflammatory bowel disease显示文摘Valeria Criscuoli Irene Modesto Ambrogio Orlando Mario Cottone 2013Expert Opinion on Pharmacotherapy2013,,12:1
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