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310篇 您的检索式:作者名="Inoki"
    题名 作者 年代 出处 被引量
1Spatial regulation of the mTORC1 system in amino acids sensing pathway显示文摘rapamycin (mTOR ) 的哺乳动物的目标是包括细胞生长,增长,细胞周期,和 autophagy 调整众多的细胞的过程的 evolutionarily 保存的 serine/threonine 蛋白质 kinase。mTOR 形成叫作 mTOR 建筑群 1 的二不同多蛋白质建筑群(mTORC1 ) , mTORC2,和每建筑群只施加不同功能。mTORC1 活动对选择禁止者 rapamycin 敏感,而 mTORC2 是抵抗的。mTORC1 被象生长因素,营养素,和察觉到精力的信号那样的许多细胞内和细胞外的暗示调整,当 mTORC2 察觉到核糖体成熟和生长因素发信号时。这评论集中于 mTORC1 小径为它的激活由察觉到细胞的滋养的可获得性的当前的理解。Tsukasa Suzuki Ken Inoki 2011Acta Biochimica et Biophysica Sinica2011,43,9:8
2Dysregulation of the TSC-mTOR pathway in human disease 显示文摘Inoki K Corradetti MN Guan KL 2005Nat Genet2005,37,1:1
3TSC2:filling the GAP in the mTOR signaling pathway显示文摘Li Y Corradetti MN Inoki K 0,,01:1
4Sphingosine-l-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice显示文摘Wang F Okamoto Y Inoki I 2010J Clin Invest2010,120,:1
5Regulation of the TSC pathway by LKBI: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome 显示文摘Corradetti MN Inoki K Bardeesy N 2004Genes Dev2004,18,13:1
6TSC2 mediates cellular energy response to control cell growth and suivival显示文摘Inoki K Zhu T Guan KL 2003Cell2003,115,5:1
7Th1/Th2-balance in anterior chamber-associated immune deviation by alloantigen显示文摘SAKAI R YAMAGAMI S INOKI T 2002Graefes Arch Clin Exp Ophthalmol2002,240,2:1
8TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling显示文摘Inoki K Li Y Zhu T 2002Nat Cell Biol2002,4,9:1
9Dysregulation of the TSC- mTOR pathway in human disease显示文摘Inoki K Corradetti MN Guan KL 2005Nat Genet2005,37,:1
10mTORC1activation in podocytes is a critical step in the development of diabetic nephropathy in mice显示文摘Inoki K Mori H Wang J 0,,06:1
11mTOR pathway as a target in tissue hypertrophy 显示文摘Lee CH Inoki K Guan KL 2007Annu Rev Pharmacol Toxicol2007,47,44:1
12Regulation of the TSC pathway by LKB1:evidence of a molecular link between tuberous scler(o)sis complex and Peutz-Jeghers syndrome显示文摘Corradetti MN Inoki K Bardeesy N 0,,:1
13Regulation of the TSC pathway by LKBl:Evidence of a molecu-lar link between tuberous sclerosis complex and Peutz-Jeghers syndrome 显示文摘Corradetti MN Inoki K Bardeesy N 2004Genes Dev2004,18,13:1
14Dysregulation of the TSC -mTOH pathway in human disease 显示文摘Inoki K Corradetti MN Guan KL 2005Nat Genet2005,37,:1
15TSC2 is phosphorylaled and inhibited by Akt and suppresses mTOR signaling显示文摘Inoki K Li Y Zhu T 2002Nat Cell Biol2002,4,9:1
16The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamyicn pathway显示文摘Corradetti M N Inoki K Guan K L 2005J Biol Chem2005,280,11:1
17TSC2 mediates cellular energy response to control cell growth and survival显示文摘Inoki K Zhu T Guan KL 2003Cell2003,115,5:1
18TSC2 is phosphorylated and inhibit- ed by Akt and suppresses roTOR signaling显示文摘Inoki K Li Y Zhu T 2002Nat Cell Binl2002,4,9:1
19Rheb GTPase is a direct target of TSC2GAP activity and regulates m TOR signaling显示文摘Inoki K Li Y Xu T 2003Genes Dev2003,17,15:1
20mT ORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice显示文摘Inoki K Mori H Wang J 2011J Clin Invest2011,121,6:1
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