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| 1 | Predictive value of C-reactive protein/albumin ratio in acute pancreatitis显示文摘BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and infection.However,their role in patients with acute pancreatitis is not clear.The present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis patients.METHODS:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June 2015.Ranson scores,Atlanta classification and CRP/albumin ratios of the patients were calculated.RESULTS:The CRP/albumin ratio was higher in deceased patients compared to survivors.The CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation rate.In addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of mortality.It was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% specificity.It was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤16.28.Patients with CRP/albumin ratio >16.28 had a 19.3 times higher chance of death.CONCLUSION:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis. | Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun Ertugrul Kayacetin | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 53 |
| 2 | 秸秆和地膜覆盖对黄土高原旱作小麦田土壤团聚体氮组分的影响显示文摘利用田间定位试验研究旱作农田不同覆盖措施对土壤团聚体氮组分的影响。基于黄土高原8年冬小麦覆盖定位试验,试验设置生育期秸秆覆盖(SM)、生育期地膜覆盖(PM)和无覆盖对照(CK)3个处理。采用干筛法测定团聚体分布特征及不同粒径团聚体中全氮(STN)、微生物量氮(MBN)和潜在可矿化氮(PNM)含量。结果表明:(1)与CK处理相比,2种覆盖处理均未在各粒径团聚体全氮含量有显著变化,但SM处理相较于PM处理提高了0-10 cm土层的1.00~0.25 mm粒径团聚体STN含量(12.88%,P<0.05)。(2)与CK处理相比,SM处理在0-10 cm土层中>2.00,2.00~1.00,<0.25 mm粒径团聚体MBN含量分别提高18.67%,24.05%,20.08%(P<0.05),且各粒径团聚体PNM含量分别提高35.13%,30.03%,42.88%(P<0.05);SM处理在10-20 cm土层中>2.00 mm粒径团聚体MBN含量提高23.02%(P<0.05),分别提高>2.00,2.00~1.00,<0.25 mm粒径团聚体PNM含量28.59%,31.31%,32.48%(P<0.05)。(3)PM处理较CK处理提高0-10 cm土层中<0.25 mm粒径团聚体PNM含量(32.34%,P<0.05)。(4)微团聚体(<0.25 mm)氮组分含量均高于大团聚(>0.25 mm)氮组分含量,但大团聚体氮组分贡献率为81.88%~87.66%。可见,SM处理可提高土壤表层大团聚体氮组分的贡献率,使更多的氮素储存在大团聚体中,而PM处理对团聚体氮素贡献率的影响作用较小。总体而言,与CK和PM处理相比,SM处理可提高总土壤氮组分含量,提高微团聚体和大团聚体氮组分含量,使更多的氮储存在大团聚体中,促进土壤氮素周转。 | 张少宏 付鑫 IHSAN Muhammad 刘文清 王俊 | 2020 | 水土保持学报2020，34，1： | 14 |
| 3 | Co-delivery of doxorubicin and quercetin via mPEG-PLGA copolymer assembly for synergistic anti-tumor efficacy and reducing cardio-toxicity显示文摘橡黄素(Que ) 是自然多功能的 bioflavonoid,并且为减少不利副作用并且提高化学疗法的药的反肿瘤功效显示出大潜力。然而,它的临床的申请在生理的系统由于很低的溶解度和结构的不稳定性被限制。此处,我们共同交付由开发 amphiphilic 聚合物包括的 biocompatible nanocarrier 的恐水病的橡黄素和吸水的 doxorubicin (纪录影片) , methoxy poly (乙烯乙二醇) 并且 poly (D, L-lactide-co-glycolide ) 分别地。反肿瘤和这个系统的预防功效被评估在细胞并且动物模型。我们说明的调查结果 Dox-Que nanoparticulate 明确的表达保护了正常脉管的 endothelial 房间免受免费的任何一个或 nanoparticulate 的伤害导致 doxorubicin 的 cytotoxicity 和增加的癌症房间死亡。与免费 doxorubicin 和它的 nanoformulation 相比,用我们的 nanosystem 的橡黄素和 doxorubicin 的合作交货 synergistically 禁止了肿瘤生长,当在浆液维持心脏的功能指示物的正常层次并且在心织物恢复组织病理学说的损坏时。这研究为提高反癌症药功效并且减少 nanoparticulate 表明有希望的策略正常纸巾上的导致化疗的毒性。 | Waseem Akhtar Qureshi Ruifang Zhao Hai Wang Tianjiao Ji Yanping Ding Ayesha Ihsan Ayeesha Mujeeb Guangjun Nie Yuliang Zhao | 2016 | Science Bulletin2016，61，21： | 9 |
| 4 | Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain显示文摘AIM: To systematically characterize specific pain patterns in the most frequent pancreatic diseases.METHODS: Pain in patients with chronic pancreatitis(n = 314), pancreatic cancer(n = 469), and other pancreatic tumors(n = 249) including mucinous(n = 20) and serous cystadenoma(n = 31), invasive(n = 37) and non-invasive intraductal papillary mucinous neoplasia(IPMN; n = 48), low stage(n = 18) and high stage neuroendocrine neoplasia(n = 44), and ampullary cancer(n = 51) was registered and correlated with clinicopathological data. Survival times were estimated by the Kaplan-Meier method. Patients alive at the follow-up time were censored. Survival curves were compared statistically using the log-rank test.RESULTS: Forty-nine point one percent of pancreatic cancer patients revealed no pain, whereas in chronic pancreatitis only 18.3% were pain free. In contrary, moderate/severe pain was registered in 15.1% in pancreatic cancer patients that was increased in chronic pancreatitis with up to 34.2%. Serous cystadenoma was asymptomatic in most cases(58.1%), whereas 78.9% of all mucinous cystadenoma patients suffered pain. In neuroendocrine neoplasia pain was not a key clinical symptom since 64% of low stage neuroendocrine neoplasia and 59% of high stage neuroendocrine neoplasia patients were pain free. Cancer localization in the pancreatic body and patients with malignant pancreatic neoplasms were associated with more severe pain. Tumor grading and stage did not show any impact on pain. Only in pancreatic cancer, pain was directly associated with impaired survival.CONCLUSION: Pancreatic pain depicts different patterns of abdominal pain sensation according to the respective pancreatic disorder and does not allow a unification of the term pancreatic pain. | Jan G D'Haese Mark Hartel Ihsan Ekin Demir Ulf Hinz Frank Bergmann Markus W Büchler Helmut Friess Güralp O Ceyhan | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 5 | Rough surface of copper-bearing titanium alloy with multifunctions of osteogenic ability and antibacterial activity显示文摘Implant-related infection and early bone integration are the main risk factors of implants for long-term service,to overcome these difficulties,SLA-TiCu surface was prepared by sandblasting and large-grits etching(SLA)treatment on a novel antibacterial titanium-copper alloy(TiCu),which is the most prevalent surface treatment with micro/submicron hierarchical structures to titanium-based implants.Effects of SLA-TiCu surface on the adhesion,proliferation,apoptosis and differentiation of MC3T3-E1 cells as well as the antibacterial activity against a common orthopedic pathogen(Staphylococcus aureus)were studied.Compared to the following surfaces:sandblasting and large-grits etched pure titanium(SLATi),mechanically ground pure titanium and TiCu alloy(M-Ti and M-TiCu),these results indicated that SLA-TiCu surface obviously enhanced the bone-related gene expressions(alkaline phosphates(ALP),collagen typeⅠ(COLⅠ),Runt-related transcription factor 2(RUN x 2),and osteopontin(OPN)).Moreover,SLA-TiCu surface could maintain a sustainable release of Cu2+ions and effectively inhibited the viability of bacteria.This study demonstrated that SLA-TiCu surface possessed multifunctional characteristics of improved osteogenic ability and antibacterial activity,making it promising as a novel implant material for hard tissue repairs such as orthopedics and dental implants. | Hui Liu Rui Liu Ihsan Ullah Shuyuan Zhang Ziqing Sun Ling Ren Ke Yang | 2020 | Journal of Materials Science & Technology2020，47，13： | 6 |
| 6 | Molecular phylogeny of Solms-laubachia(Brassicaceae) s.l.,based on multiple nuclear and plastid DNA sequences,and its biogeographic implications显示文摘The Hengduan Mountains region of south-west China is a noted biodiversity hotspot,but the geographic origins and historical assembly of its rich endemic flora,including the sky-island species of Solms-laubachia Muschl.(Brassicaceae),have been little studied.Previous molecular studies on the phylogeny of Solms-laubachia showed it to be paraphyletic,leading to considerable expansion not only of its taxonomic limits,but also its geographic range,with the inclusion of taxa from outside the Hengduan region.However,these studies provided little resolution of interspecific relationships,preventing inferences about historical biogeography within the clade.In the present study,new sequence data from two nuclear genes(LEAFY and G3pdh) and two chloroplast intergenic spacers(petN-psbM and psbM-trnD) were combined with existing markers to increase phylogenetic signals.Phaeonychium villosum(Maxim.) Al-Shehbaz was found to be nested within Solms-laubachia s.l.In general,phylogenetic relationships appear to be a good predictor of geography,with the Hengduan Mountain endemics embedded in a paraphyletic grade of species from the western Himalayas and central Asia,but they also imply morphological homoplasy.Incongruence was detected between the nuclear and chloroplast gene trees,perhaps resulting from incomplete lineage sorting of ancestral polymorphisms.The crown age of Solms-laubachia s.l.was estimated to be approximately 1.42-3.68 mya,using Bayesian relaxed molecular clock analysis.Historical biogeographic analysis using a parametric dispersal-extinction-cladogenesis model inferred central Asia and the western Himalayas as most probable ancestral range of Solms-laubachia s.l.,and estimated higher rates of eastward expansion than westward during the diversification of descendant lineages.In summary,our results suggest that Solms-laubachia s.l.originated during the Pliocene in central Asia,and subsequently migrated eastward into the Hengduan Mountains,colonizing sky-island,alpine scree-slope habitats that may have provided novel ecological opportunity and accelerated speciation,ultimately establishing this region as the present center of diversity of the genus. | Ji-Pei YUE Hang SUN David A. BAUM jian-Hua LI Ihsan A. AL-SHEHBAZ Richard REE | 2009 | Journal of Systematics and Evolution2009，47，5： | 6 |
| 7 | Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis显示文摘AIM:To investigate in vitro effects of propofol,midazolam and dexmedetomidine,which are commonly used anaesthesic or sedatives,on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic peritonitis.METHODS:Spontaneous contractions of isolated ileum muscle segments from sham operated rats and those exposed to peritonitis,were studied in vitro.The amplitude and the frequency of spontaneous contractions of ileum muscle segments were studied after adding dexmetetomidine,propofol,and midazolam to the organ bath in a cumulative manner.RESULTS:Both amplitude(85.2±6.6 vs 47.4±7.1)and frequency(32.8±4.6 vs 20.2±3.9)of spontaneous contractions in ileum smooth muscle segments were decreased significantly in the peritonitis group compared to the control group(P<0.05).Dexmedetomidine significantly increased the amplitude of spontaneous contractions(85.2±6.6 vs 152.0±5.4,P<0.05)whereas,propofol(85.2±6.6 vs 49.6±4.8,P<0.05)and midazolam(85.2±6.6 vs 39.2±4.5,P<0.05)decreased it in both control and peritonitis groups.The frequency of spontaneous contractions were significantly decreased by propofol in both control(32.8±4.6 vs 18.2±3.4,P<0.05)and peritonitis groups 20.2±3.9 vs 11.6±3.2,P<0.05).Dexmedetomidine and midazolam did not cause significant changes in the number of spontaneous contractions in both control and the peritonitis groups(P>0.05).CONCLUSION:Propofol,midazolam and dexmedetomidine have various in vitro effects on spontaneous contractions of the rat ileum.While dexmedetomidine augments the spontaneous contraction of the rat ileum,propofol attenuates it.However,the effects of these compounds were parallel in both control and peritonitis groups. | Cengiz Aydin Ihsan Bagcivan Sinan Gursoy Ahmet Altun Omer Topcu Ayhan Koyuncu | 2009 | World Journal of Gastroenterology2009，15，13： | 6 |
| 8 | 持续高温胁迫环境下内生菌产生植物激素和有机酸促进粳稻生长的研究(英文)显示文摘目的:研究在高温胁迫环境下内生菌(Paecilomyces formosus LWL1)对粳稻生长的影响。创新点:首次探讨P.formosus LWL1产生的植物激素和有机酸在缓解粳稻热应激方面的作用。方法:比较正常和高温胁迫两种环境下,P.formosus LWL1对Dongjin粳稻植株的生长状况及内源性脱落酸、茉莉酸和总蛋白水平变化的作用。结论:内生菌在正常和高温胁迫条件下均能显著提高植物生长情况,包括株高、鲜重、干重和叶绿素含量。内生菌组的植株具有更低的内源性胁迫信号化合物水平及提升的总蛋白量,表明其具有保护粳稻的作用。这种内生菌可能有利于作物在高温环境下生长的耐受性。 | Muhammad WAQAS Abdul Latif KHAN Raheem SHAHZAD Ihsan ULLAH Abdur Rahim KHAN In-Jung LEE | 2015 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2015，16，12： | 5 |
| 9 | 中巴传统药物研究比较显示文摘目的:探讨中巴两国传统药物资源的异同点,寻找潜在的合作点。方法:对巴基斯坦与中国传统药物的发展现状、药用资源、存在问题等进行了文献与实地调研研究。结果:巴基斯坦在医药保健品消费方面是最具潜力的市场之一。巴基斯坦的传统医药体系是基于希波克拉底理论框架的希腊阿拉伯体系,农村医疗及农业经济发展与传统药物息息相关。过度开采、大量放牧、乱砍乱伐、土地退化等造成大量野生药用植物资源灭绝或濒临灭绝。巴基斯坦许多植物资源与我国共有,有些药用植物的临床功效与中国一致,还有一些药用植物在中巴两国的临床应用各有不同偏向。结论:巴基斯坦与中国生物技术和民族医药的合作可为两国带来互惠互利。通过人工种植或寻找替代品不仅可以缓解巴基斯坦药物资源耗竭问题,而且能够促进中国的贸易出口和科技输出,提升我国的国际竞争力与影响力。 | 黄先菊 陈慧 Awais Ihsan | 2017 | 亚太传统医药2017，13，13： | 5 |
| 10 | A case study of multi-seam coal mine entry stability analysis with strength reduction method显示文摘In this paper,the advantage of using numerical models with the strength reduction method(SRM) to evaluate entry stability in complex multiple-seam conditions is demonstrated.A coal mine under variable topography from the Central Appalachian region is used as a case study.At this mine,unexpected roof conditions were encountered during development below previously mined panels.Stress mapping and observation of ground conditions were used to quantify the success of entry support systems in three room-and-pillar panels.Numerical model analyses were initially conducted to estimate the stresses induced by the multiple-seam mining at the locations of the affected entries.The SRM was used to quantify the stability factor of the supported roof of the entries at selected locations.The SRM-calculated stability factors were compared with observations made during the site visits,and the results demonstrate that the SRM adequately identifies the unexpected roof conditions in this complex case.It is concluded that the SRM can be used to effectively evaluate the likely success of roof supports and the stability condition of entries in coal mines. | Tulu Ihsan Berk Esterhuizen Gabriel S. Klemetti Ted Murphy Michael M. Sumner James Sloan Michael | 2016 | International Journal of Mining Science and Technology2016，26，2： | 5 |
| 11 | 基于网络药理学及分子对接探讨香连片对新型冠状病毒肺炎(COVID-19)的机制研究显示文摘目的:基于网络药理学及分子对接技术探讨香连片对新型冠状病毒肺炎(Corona Virus Disease 2019, COVID-19)的作用机制。方法:通过中药系统药理学数据库与分析平台(Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform, TCMSP)、PubChem数据库、生物信息学分析工具(a bioinformatics analysis tool for molecular mechanism of traditional Chinese medicine, BATMAN-TCM)及SwissTarget Prediction平台查询香连片活性成分及其对应的靶点基因;根据大于2倍中位数的节点度值(degree)为条件,筛选香连片关键活性成分,并运用Cytoscape 3.6.1软件绘制关键活性成分-对应靶点网络;通过GeneCards及PHARMGKB疾病数据库,以'coronavirus pneumonia'、'COVID-19'及'SARS-CoV-2'为关键词进行检索疾病靶点基因。运用Cytoscape 3.6.1软件进行交集,得到共同靶点并构建成分-靶点-疾病网络图;通过STRING网站对共同靶点构建蛋白相互作用(Protein Protein interaction, PPI)网络,通过DAVID数据库对共同靶点进行基因本位(gene ontology, GO)和京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes, KEGG)分析;利用CB-Dock网站对筛选出的活性成分及抗病毒化药和SARS-CoV-2 3CL水解酶及血管紧张素转化酶Ⅱ (angiotensin converting enzyme Ⅱ, ACE2)进行分子对接。结果:香连片共得到41个活性成分,其中16个关键活性成分,并与疾病靶点相交得到24个共同靶点;GO功能富集得到分子功能(molecular function, MF)、细胞组分(cellular component, CC)及其所参与的生物过程(biological process, BP)分别为125条、16条及24条;KEGG富集得到94条通路,其通路多与免疫反应和炎症反应有关,主要有PI3K-Akt、Ras、HIF-1、MAPK、NF-kB以及TNF等信号通路;分子对接得出黄柏酮、氧化小檗碱、吴茱萸碱、吴茱萸次碱及豆甾醇等多种成分与SARS-CoV-2 3CL水解酶及ACE2的对接亲和力均强于2种临床化学药物(阿比多尔及利巴韦林)。结论:香连片多是通过作用于MAPK家族、IL1B、NFKB1、CASP3、CCL5、TNF等靶点因子来调节PI3K-Akt、MAPK、NF-kB及TNF等炎症免疫通路,以多成分、多靶点、多途径参与COVID-19的多种生理过程,从而对COVID-19有一定治疗作用;在中药成分上,黄柏酮、氧化小檗碱、吴茱萸碱、吴茱萸次碱、豆甾醇、吴茱萸酰胺类成分等可以很好作用于COVID-19治疗中涉及到的2种关键酶(SARS-CoV-2 3CL水解酶及ACE2),故这几种中药单体成分有作为治疗COVID-19的新药潜能。 | 董悦 李竣 佟海英 黄先菊 Awais Ihsan | 2021 | 中国医院药学杂志2021，41，7： | 5 |
| 12 | Plasma spray of biofunctional(Mg, Sr)-substituted hydroxyapatite coatings for titanium alloy implants显示文摘Plasma-sprayed hydroxyapatite (HA) coatings have been widely utilized in load-bearing titanium alloy implants. In this study, Mg, Sr co-substituted HA ((Mg,Sr)-HA) nano-scale powders have been synthesized, which are further used to prepare (Mg,Sr)-HA coatings on Ti-6A1-4V alloys in order to improve the biological functions. The average size of (Mg,Sr)-HA nano particles is ~75nm. The average bonding strength for (Mg,Sr)-HA coating and samples after heat treatment at 500℃ or 600℃ for 3h are 26.17±2.11 MPa, 36.07±4.48 MPa and 37.07 ±2.95 MPa, respectively. There is a significantly increase of bonding strength likely due to low residual stress after heated treatment.MC3T3-E1 cells show a high proliferation rate when cultured with (Mg,Sr)-HA coating extract compared to the normal culture medium, which also exhibit large extension and depositi on of extracellular matrices when adhered on the coating surfaces. Thus, these (Mg,Sr)-HA coatings show high bonding strength and improved biological functions, which offer promising future applications in the fields of orthopedics and dentistry. | Lei Cao Ihsan Ullah Na Li Shiyu Niu Rujie Sun Dandan Xia Rui Yang Xing Zhang | 2019 | Journal of Materials Science & Technology2019，35，5： | 5 |
| 13 | Effects of vernal and allergic conjunctivitis on severity of keratoconus显示文摘AIM: To demonstrate the effects of two different types of allergic conjunctivitis on severity of keratoconus (KC). ·METHODS: We retrospectively reviewed the medical records of 171 KC patients referred between June 2010 and June 2011. The KC patients were divided into 3 groups as KC (group A), KC with vernal keratoconjunctivitis (VKC) (group B) and KC with allergic conjunctivitis (AC) (group C). Main outcome measures were demographic and ocular clinical features including age at presentation, gender, spherical equivalent (SE), best spectacle corrected visual acuity (BCVA), mean keratometric measurement (Km), central corneal thickness (CCT), and intraocular pressure (IOP). Groups were compared in term of study variables. · RESULTS: The median age at presentation was significantly lower in group B (P <0.001). According to the median SE (P =0.003), BCVA(P =0.022), Km(P <0.001), CCT (P =0.015) and Amsler-Krumeich classification (P < 0.001), KC was more severe in group B. There was no significant difference in terms of IOP and corrected IOP among the groups (P =0.44), however there were 4 patients who had increased corrected IOP developed after topical corticosteroid use in group B. The differences among the groups persisted even after controlling for age and gender. · CONCLUSION: Our findings demonstrated a more severe KC in VKC patients despite their younger age which suggests evaluation of VKC patients as a separate group in keratoconus disease. | Abdullah Kursat Cingu Yasin Cinar Fatih Mehmet Turkcu Alparslan Sahin Seyhmus Ari Harun Yuksel Muhammed Sahin Ihsan Caca | 2013 | International Journal of Ophthalmology(English edition)2013，6，3： | 4 |
| 14 | Design concerns of room and pillar retreat panels显示文摘Why do some room and pillar retreat panels encounter abnormal conditions? What factors deserve the most consideration during the planning and execution phases of mining and what can be done to mitigate those abnormal conditions when they are encountered? To help answer these questions, and to determine some of the relevant factors influencing the conditions of room and pillar(R & P) retreat mining entries, four consecutive R & P retreat panels were evaluated. This evaluation was intended to reinforce the influence of topographic changes, depth of cover, multiple-seam interactions, geological conditions, and mining geometry. This paper details observations were made in four consecutive R & P retreat panels and the data were collected from an instrumentation site during retreat mining. The primary focus was on the differences observed among the four panels and within the panels themselves. The instrumentation study was initially planned to evaluate the interactions between primary and secondary support, but produced rather interesting results relating to the loading encountered under the current mining conditions. In addition to the observation and instrumentation, numerical modeling was performed to evaluate the stress conditions. Both the La Model 3.0 and Rocscience Phase 2 programs were used to evaluate these four panels. The results of both models indicated a drastic reduction in the vertical stresses experienced in these panels due to the full extraction mining in overlying seams when compared to the full overburden load. Both models showed a higher level of stress associated with the outside entries of the panels. These results agree quite well with the observations and instrumentation studies performed at the mine. These efforts provided two overarching conclusions concerning R & P retreat mine planning and execution. The first was that there are four areas that should not be overlooked during R & P retreat mining: topographic relief, multiple-seam stress relief, stress concentrations near the gob edge,and geologic changes in the immediate roof. The second is that in order to successfully retreat an R &P panel, a three-phased approach to the design and analysis of the panel should be conducted: the planning phase, evaluation phase, and monitoring phase. | Klemetti Ted M. Sears Morgan M. Tulu Ihsan B. | 2017 | International Journal of Mining Science and Technology2017，27，1： | 4 |
| 15 | A review of chemical absorption of carbon dioxide for biogas upgrading显示文摘Significant attention has been given to biogas production, purification and upgrading as a renewable and clean fuel supplement. Biogas is a product of an anaerobic digestion process comprising methane, carbon dioxide,and trace amounts of other gases. Biogas purification removes trace gases in biogas for safe utilisation. Biogas upgrading produces methane-rich biogas by removing bulk carbon dioxide from the gas mixture. Several carbon dioxide removal techniques can be applied for biogas upgrading. However, chemical absorption of carbon dioxide for biogas upgrading is of special significance due to its operation at ambient or near ambient temperature and pressure, thus reducing energy consumption. This paper reviews the chemical absorption of carbon dioxide using amine scrubbing, caustic solvent scrubbing, and amino acid salt solution scrubbing. Each of these techniques for biogas upgrading is discussed. The paper concludes that an optimised implementation of the chemical absorption techniques for biogas upgrading requires further research. | Fouad R.H. Abdeen Maizirwan Mel Mohammed Saedi Jami Sany Izan Ihsan Ahmad Faris Ismail | 2016 | Chinese Journal of Chemical Engineering2016，24，6： | 3 |
| 16 | Effect of low molecular weight heparin (enoxaparin) on congenital cataract surgery显示文摘AIM: To assess the efficacy of intracameral enoxaparin (a low-molecular-weight heparin) infusion, in variable doses on postoperative inflammatory response in congenital cataract surgery.METHODS: It is a prospective, randomized controlled trial. Eighty eyes of 53 children with congenital cataract were enrolled in this study. Every eye had primary posterior capsulorrhexis and intraocular lens (IOL) implantation after lens aspiration. The eyes were divided into 4 equal groups. In group 1 balanced salt solution (BSS) without enoxaparin was used as an irrigation solution. Whereas in group 2, 3 and 4, 40mg, 20mg and 10mg enoxaparin in 500mL BSS was used respectively. The inflammatory response in the anterior chamber was compared among the groups with slit-lamp biomicroscopy.RESULTS: The mean follow-up period was (17.75±3.95) months in group 1, (18.00±5.15) months in group 2, (19.20±5.47) months in group 3 and (18.65±5.16) months in group 4. Mean number of inflammatory cells in the anterior chamber in group 1 was significantly higher than that of group 2, 3, 4 (P<0.001). There was fibrin formation in the anterior chambers of 3 eyes in group 1 and one eye in group 4. There was synechiae formation in 3 eyes of group 1 and one eye of group 4. There was no significant difference among the groups by means of fibrin or synechiae formation (P>0.05). There were IOL precipitates in 4 eyes of group 1 and 2 eyes of group 4. IOL precipitate formation was significantly higher in group 1 than that of group 2 and 3 in which there was no IOL precipitate (P=0.048). There was IOL subluxation in only one eye of group 1, 3 and 4 while no subluxation was observed in group 2 (P>0.05). There was no statistically significant difference detected about IOL subluxation occurance in all 4 groups (P>0.05). CONCLUSION: Complications of cataract surgery in congenital cataract patients associated with postoperative inflammatory response found to be decreased with the use of enoxaparin in intraocular infusion solutions. Furthermore according to our results the anti-inflammatory effect of enoxaparin was dose dependant. | Ihsan aa Alparslan Sahin Abdullah Kürsat Cingü Seyhmus Ari Fuat Alakus Yasin inar | 2012 | International Journal of Ophthalmology(English edition)2012，5，5： | 3 |
| 17 | New Insights into Petroleum Migration-Accumulation Dynamic Systems and Their Division within Petroleum Systems显示文摘Since the concept of petroleum migration-accumulation dynamic system (PMADS) was introduced in the 1990s, its definition, division and even denomination have long been in disagreement. This article aims to further discuss and try to clarify this concept and to explore more reasonable approaches to the division of PMADSs on the basis of our studies on petroleum migration and accumulation in some petroliferous basins of China, especially those from western China. According to the studies, we define PMADS as a relatively independent natural hydrocarbon migrating and accumulating system within a petroleum system. Its extent is supposed to cover the whole migration pathway starting from a hydrocarbon provenance throughout to an accumulation or a group of accumulations of same source. Just like petroleum systems, a petroleum migration-accumulation system is also an important natural unit for petroleum exploration and assessment in petroleum basins. Its position in a basin is right between a petroleum system and a play. A petroleum system has either a number of migration-accumulation systems or one system only. However, the key element of a petroleum system is the source of hydrocarbon; a petroleum system has a distinct hydrocarbon kitchen and is different from its neighboring ones in terms of hydrocarbon kitchens. In contrast, different migration-accumulation systems within the same petroleum system have a shared source kitchen but different characteristics of migration and accumulation to form hydrocarbon accumulations. As far as the division of petroleum migration-accumulation systems (PMASs) is concerned, 8 major approaches are proposed, including those based on pool-forming dynamic mechanisms, location of hydrocarbon accumulation relative to the source kitchen, phase states of migration and accumulation, migration patterns and directions, geneses of accumulations, reservoir pressure systems, depositional systems and facies, and integrated method, of which the integrated approach is underlined with regard to the division of PMASs in a complex petroleum system like those in West-China superimposed basins. | 赵靖舟 Ihsan S Al-aasm | 2012 | Journal of Earth Science2012，23，5： | 3 |
| 18 | Nerve Growth Factor and Artemin Are Paracrine Mediators of Pancreatic Neuropathy in Pancreatic Adenocarcinoma显示文摘 | Güralp O. Ceyhan Karl-Herbert Sch?fer Annika G. Kerscher Ulrich Rauch Ihsan Ekin Demir Mustafa Kadihasanoglu Carolin B?hm Michael W. Müller Markus W. Büchler Nathalia A. Giese Mert Erkan Helmut Friess | 2010 | Annals of Surgery2010，，5： | 2 |
| 19 | Neural invasion in pancreatic cancer: A mutual tropism between neurons and cancer cells显示文摘 | Güralp O. Ceyhan Ihsan Ekin Demir Burak Altintas Ulrich Rauch Gerald Thiel Michael W. Müller Nathalia A. Giese Helmut Friess Karl-Herbert Sch?fer | 2008 | Biochemical and Biophysical Research Communications2008，，3： | 2 |
| 20 | Using LaModel to analyze coal bumps显示文摘Coal bumps have long been a safety hazard in coal mines, and even after decades of research, the exact mechanics that cause coal bumps are still not well understood. Therefore, coal bumps are still difficult to predict and control. The LaModel program has a long history of being used to effectively analyze displacements and stresses in coal mines, and with the recent addition of energy release and local mine stiffness calculations, the LaModel program now has greatly increased capabilities for evaluating coal bump potential. This paper presents three recent case histories where coal stress, pillar safety factor, energy release rate and local mine stiffness calculations in LaModel were used to evaluate the pillar plan and cut sequencing that were associated with a number of bumps. The first case history is a longwall mine where a simple stress analysis was used to help determine the limiting depth for safely mining in bump-prone ground. The second case history is a room-and-pillar retreat mine where the LaModel analysis is used to help optimize the pillar extraction sequencing in order to minimize the frequent pillar line bumps. The third case history is the Crandall Canyon mine where an initial bump and then a massive pillar collapse/bump which killed 6 miners is extensively back-analyzed. In these case histories, the calculation tools in LaModel are ultimately shown to be very effective for analyzing various aspects of the bump problem, and in the conclusions, a number of critical insights into the practical calculation of mine failure and stability developed as a result of this research are presented. | Keith A.Heasley Ihsan Berk Tulu | 2018 | International Journal of Mining Science and Technology2018，28，5： | 2 |
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