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| 1 | Volume expansion with albumin compared to gelofusine in children with severe malaria:results of a controlled trial显示文摘 | Akech S Gwer S Idro R | | 0，，： | 1 |
| 2 | Numerical solution of both ends fixed deep beams 显示文摘 | AHMED S R IDROS B M UDDIN M W | 1996 | Computer & Structures1996，61，1： | 1 |
| 3 | Analysis of the indications for routine lumber puncture and results of cerebrospinal fluid examination in children admitted to the paediatric wards of two hospitals in East Africa显示文摘 | Herbert G Ndiritu M Idro R | 2006 | Tanzan Health Res Bull2006，8，1： | 1 |
| 4 | Does Mutual Fund Flow Reflect Investor Sentiment显示文摘 | Idro D | 2004 | Journal of Behavioral Finance2004，，5： | 1 |
| 5 | An al ysis of the indicat ions for rout in e lum ber pun cture and result s of cerebrospinal f luidexamination in children admit t ed t o the paediat ricw ar ds of tw ohos pit al s in EastAf rica显示文摘 | Herbert G Ndiritu M Idro R | 2006 | Tanzan Health ResBull2006，8，1： | 1 |
| 6 | Continuous EEGmonitoring in Kenyan children with non-traumatic coma显示文摘 | Gwer S Idro R Fegan G | 2012 | Arch Dis Child2012，97，4： | 1 |
| 7 | Fosphenytoin for seizureprevention in childhood coma in Africa: a randomized clinicaltrial 显示文摘 | Gwer SA Idro RI Fegan G | 2013 | J Crit Care2013，28，6： | 1 |
| 8 | Analysis of the indications for routine lumber puncture and results of eerebrospinal fluid examination in children admitted to the paediatricwards of two hospitals in EastAfrica 显示文摘 | Herbert G Ndiritu M Idro R | 2006 | Tanzan Health ResBull2006，8，1： | 1 |
| 9 | Report of the first international workshop on onchocerciasis-associated epilepsy显示文摘Background:Recently,several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy(OAE)may constitute an important but neglected public health problem in many countries where onchocerciasis is still endemic.Main text:On October 12-14th 2017,the first international workshop on onchocerciasis-associated epilepsy(OAE)was held in Antwerp,Belgium.The workshop was attended by 79 participants from 20 different countries.Recent research findings strongly suggest that O.volvulus is an important contributor to epilepsy,particularly in meso-and hyperendemic areas for onchocerciasis.Infection with O.volvulus is associated with a spectrum of epileptic seizures,mainly generalised tonic-clonic seizures but also atonic neck seizures(nodding),and stunted growth.OAE is characterised by an onset of seizures between the ages of 3-18 years.Multidisciplinary working groups discussed topics such as how to 1)strengthen the evidence for an association between onchocerciasis and epilepsy,2)determine the burden of disease caused by OAE,3)prevent OAE,4)improve the treatment/care for persons with OAE and affected families,5)identify the pathophysiological mechanism of OAE,and 6)deal with misconceptions,stigma,discrimination and gender violence associated with OAE.An OAE Alliance was created to increase awareness about OAE and its public health importance,stimulate research and disseminate research findings,and create partnerships between OAE researchers,communities,advocacy groups,ministries of health,non-governmental organisations,the pharmaceutical industry and funding organizations.Conclusions:Although the exact pathophysiological mechanism underlying OAE remains unknown,there is increasing evidence that by controlling and eliminating onchocerciasis,OAE will also disappear.Therefore,OAE constitutes an additional argument for strengthening onchocerciasis elimination efforts.Given the high numbers of people with epilepsy in O.volvulus-endemic regions,more advocacy is urgently needed to provide anti-epileptic treatment to improve the quality of life of these individuals and their families. | Robert Colebunders Michel Mandro Alfred K.Njamnshi Michel Boussinesq An Hotterbeekx Joseph Kamgno Sarah O’Neill Adrian Hopkins Patrick Suykerbuyk Maria-Gloria Basanez Rory J.Post Belen Pedrique Pierre-Marie Preux Wilma A.Stolk Thomas B.Nutman Richard Idro | 2018 | Infectious Diseases of Poverty2018，7，1： | 1 |
| 10 | Qualitative evaluation of the outcomes of care and treatment for children and adolescents with nodding syndrome and other epilepsies in Uganda显示文摘Background:In 2012,the Ugandan Government declared an epidemic of Nodding Syndrome(NS)in the Northern districts of Gulu,Kitgum,Lamwo and Pader.Treatment guidelines were developed and NS treatment centres were established to provide symptomatic control and rehabilitation.However,a wide gap remained between the predefined care standards and the quality of routine care provided to those affected.This study is to qualitatively assess adherence to accepted clinical care standards for NS;identify gaps in the care of affected children and offer Clinical Support Supervision(CSS)to Primary Health Care(PHC)staff at the treatment centres;and identify psychosocial challenges faced by affected children and their caregivers.Methods:This case study was carried out in the districts of Gulu,Kitgum,Lamwo and Pader in Uganda from September to December in 2015.Employing the 5-stage approach of Clinical Audit,data were collected through direct observations and interviews with PHC providers working in public and private-not-for-profit health facilities,as well as with caregivers and political leaders.The qualitative data was analysed using Seidel model of data processing.Results:Clinical Audit and CSS revealed poor adherence to treatment guidelines.Many affected children had suboptimal NS management resulting in poor seizure control and complications including severe burns.Root causes of these outcomes were frequent antiepileptic drugs stock outs,migration of health workers from their work stations and psychosocial issues.There was hardly any specialized multidisciplinary team(MDT)to provide for the complex rehabilitation needs of the patients and a task shifting model with inadequate support supervision was employed,leading to loss of skills learnt.Reported psychosocial and psychosexual issues associated with NS included early pregnancies,public display of sexual behaviours and child abuse.Conclusions:Despite involvement of relevant MDT members in the development of multidisciplinary NS guidelines,multidisciplinary care was not implemented in practice.There is urgent need to review the NS clinical guidelines.Quarterly CSS and consistent anticonvulsant medication are needed at health facilities in affected communities.Implementation of the existing policies and programs to deal with the psychosocial and psychosexual issues that affect children with NS and other chronic conditions is needed. | Catherine Abbo Amos Deogratius Mwaka Bernard Toliva Opar Richard Idro | 2019 | Infectious Diseases of Poverty2019，8，2： | 1 |
| 11 | Is nodding syndrome an Onchceerca volvulus induced neuro-inflammatory disorder? Uganda's story of research in understanding the disease 显示文摘 | Idro R Opar B Wamala J | 2016 | Int J Infect Dis2016，45，： | 1 |
| 12 | Farm level processing of virgin coconut oil and its economic implications 显示文摘 | Rindengan Barlina dan Amrizal idroes | 2005 | Cocoinfo International2005，，： | 1 |
| 13 | Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of onchocerciasis control measures显示文摘Background:Around 2007,a nodding syndrome(NS)epidemic appeared in onchocerciasis-endemic districts of northern Uganda,where ivermeain mass distribution had never been implemented.This study evaluated the effect of community-directed treatment with ivermectin(CDTI)and ground larviciding of rivers initiated after 2009 and 2012 respectively,on the epidemiology of NS and other forms of epilepsy(OFE)in some districts of northern Uganda.Methods:In 2012,a population-based community survey of NS/epilepsy was carried out by the Ugandan Ministry of Health in Kitgum and Pader districts.In August 2017,we conducted a new survey in selected villages of these districts and compared our findings with the 2012 data.In addition,two villages in Moyo distria(where CDTI was ongoing since 1993)served as comparative onchocerciasis-endemic sites in which larviciding had never been implemented.The comparison between 2012 and 2017 prevalence and cumulative incidence were done using the Fisher's and Pearson's Chi-square tests at 95%level of significance.Results:A total of 2138 individuals in 390 households were interviewed.In the seleaed villages of Kitgum and Pader,there was no significant decrease in prevalence of NS and OFE between 2012 and 2017.However,the cumulative incidence of all forms of epilepsy decreased from 1165 to 130 per 100000 persons per year(P=0.002);that of NS decreased from 490 to 43 per 100000 persons per year(P=0.037);and for OFE from 675 to 87 per 100000 persons per year(P=0.024).The median age of affeaed persons(NS and OFE)shifted from 13.5(IQR:11.0-15.0)years in 2012 to 18.0(IQR:15.0-20.3)years in 2017;P<0.001.The age-standardized prevalence of OFE in Moyo in 2017 was 4.6%,similar to 4.5%in Kitgum and Pader.Conclusions:Our findings support the growing evidence of a relationship between infection by Onchocerca volvulus and some types of childhood epilepsy,and suggest that a combination of bi-annual mass distribution of ivermectin and ground larviciding of rivers is an effective strategy to prevent NS and OFE in onchocerciasis-hyperendemic areas. | Nolbert Gumisiriza Frank Mubiru Joseph Nelson Siewe Fodjo Martin Mbonye Kayitale An Hotterbeekx Richard Idro Issa Makumbi Tom Lakwo Bernard Opar Joice Kaducu Joseph Francis Wamala Robert Colebunders | 2020 | Infectious Diseases of Poverty2020，9，2： | 1 |
| 14 | Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study显示文摘 | Manish Sadarangani Claire Seaton J Anthony G Scott Bernhards Ogutu Tansy Edwards Agnes Prins Hellen Gatakaa Richard Idro James A Berkley Norbert Peshu Brian G Neville Charles R Newton | 2008 | Lancet Neurology2008，，2： | 1 |
| 15 | Iron deficiency andacute seizures:Results from children living in rural Kenyaand a meta-analysis显示文摘 | Idro R Gwer S Williams TN | 2010 | PLoS 0ne2010，，14： | 1 |
| 16 | Severe anaemia in childhood cerebral malaria is associated with profound coma显示文摘 | Idro R | 2003 | Afr Health Sci2003，3，1： | 1 |
| 17 | Iron deficiency and acute seizures:results from children living in rural Kenya and a meta-analysis显示文摘 | IDRO R GWER S WILLIAMS TN | 2010 | PLoS One2010，5，14： | 1 |
| 18 | 脑型疟疾引发持久性神经和认知功能障碍的危险因素显示文摘Background: Persisting neurological and cognitive impairments are common after cerebralmalaria. Although risk factors for gross deficits on discharge have been described, few studies have examined those associated with persistent impairments. Methods: The risk factors for impairments following cerebral malaria were determined by examining hospital records of 143 children aged 6-9 years, previously admitted with cerebral malaria, who were assessed at least 20 months after discharge to detect motor, speech and language, and other cognitive (memory, attention, and non-verbal functioning) impairments. Results: The median age on admission was 30 months (IQR 19-42) and the median time from discharge to assessment was 64 months (IQR 40-78). Thirty four children (23.8% ) were defin-ed as having impairments: 14 (9.8% ) in motor, 16 (11.2% ) in speech and language, and 20 (14.0% ) in other cognitive functions. Previous seizures (OR 5.6, 95% CI 2.0 to 16.0), deep coma on admission (OR 28.8, 95% CI 3.0 to 280), focal neurological signs observed during admission (OR 4.6, 95% CI 1.1 to 19.6), and neurological deficits on discharge (OR 4.5, 95% CI 1.4 to 13.8) were independently associated with persisting impairments. In addition, multiple seizures were associated with motor impairment, age < 3 years, severe malnutrition, features of intracranial hypertension, and hypoglycaemia with language impairments, while prolonged coma, severe malnutrition, and hypoglycaemia were associated with impairments in other cognitive functions. Conclusions: Risk factors for persisting neurological and cognitive impairments following cerebral malaria include multiple seizures, deep/prolonged coma, hypoglycaemia, and clinical features of intracranial hypertension. Although there are overlaps in impaired functions and risk factors, the differences in risk factors for specific functions may suggest separate mechanisms for neuronal damage. These factors could form the basis of future preventive strategies for persisting impairments. | Idro R. Carter J.A. Fegan G. 张振 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，9： | 0 |
| 19 | Comprehensive management of epilepsy in onchocerciasis-endemic areas:lessons learnt from community-based surveys显示文摘Background:Onchocerciasis-endem ic regions are known to have a high epilepsy prevalence.Limited resources in these areas and poor access to healthcare by persons with epilepsy(PWE)result in a wide anti-epileptic treatment gap,poor seizure control and a high burden of seizure-related complications.Recent comm unity-based surveys highlight the need for epilepsy managem ent strategies suitable for remote onchocerciasis-endemic villages to ensure better health outcom es for PWE.In this paper,we propose a feasible approach to manage PWE in such settings.Main text:Improved management of PWE in onchocerciasis-endemic areas may be achieved by decentralizing epilepsy care.Simplified approaches for the diagnosis and treatment of epilepsy may be used by non-physicians,under the supervision of physicians or specialists.To reduce the treatment gap,a regular supply of subsidized anti-epileptic drugs(AED)appropriate for different types of onchocerciasis-associated epilepsy should be instituted.Setting up a communitybased epilepsy surveillance system will enable early diagnosis and treatment of PWE thereby preventing complications.Community awareness programs on epilepsy must be implemented to reduce stigma and facilitate the social rehabilitation of PWE.Finally,strengthening onchocerciasis elimination programs by optimizing community-directed treatment with iverm eain(CDTI)and considering alternative treatment strategies might reduce the incidence of epilepsy.Conclusions:A community-based approach with task-shifting of epilepsy care from specialists to non-physician health workers will reduce epilepsy-associated morbidity.Increased advocacy and collaboration with various stakeholders is needed to establish a sustainable,cost-effective chronic care model for epilepsy that will significantly improve the quality of life of PWE in onchocerciasis-endemic regions. | Joseph Nelson Siewe Fodjo Marieke C.J.Dekker Richard Idro Michel Ndahura Mandro Pierre-Marie Preux Alfred K.Njamnshi Robert Colebunders | 2019 | Infectious Diseases of Poverty2019，8，1： | 0 |
| 20 | 2010年11月曼谷天然橡胶交易价显示文摘2009年椰油(CNO)价格上涨导致进口需求减少。由于全球经济危机导致经济增长缓慢,月桂油主要消费国美国、欧盟国家和中国只能重新调整其需求,包括棕油(PKO)的需求。因此,PKO进口量大增,而CNO进口量减少。 | Amrizal Idroes 黄艳 | 2010 | 世界热带农业信息2010，，12： | 0 |
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