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1Roles and regulation of bone morphogenetic protein-7 in kidney development and diseases显示文摘The gene encoding bone morphogenetic protein-7(BMP7) is expressed in the developing kidney in embryos and also in the mature organ in adults. During kidney development, expression of BMP7 is essential to determine the final number of nephrons in and proper size of the organ. The secreted BMP7 acts on the nephron progenitor cells to exert its dual functions: To maintain and expand the progenitor population and to provide them with competence to respond to differentiation cues, each relying on distinct signaling pathways. Intriguingly, in the adult organ, BMP7 has been implicated in protection against and regeneration from injury. Exogenous administration of recombinant BMP7 to animal models of kidney diseases has shown promising effects in counteracting inflammation, apoptosis and fibrosis evoked upon injury. Although the expression pattern of BMP7 has been well described, the mechanisms by which it is regulated have remained elusive and the processes by which the secretion sites of BMP7 impinge upon its functions in kidney development and diseases have not yet been assessed. Understanding the regulatory mechanisms will pave the way towards gaining better insight into the roles of BMP7, and to achieving desired control of the gene expression as a therapeutic strategy for kidney diseases.Taro Tsujimura Mana Idei Masahiro Yoshikawa Osamu Takase Keiichi Hishikawa 2016World Journal of Stem Cells2016,8,9:6
2Molecularly imprinted polymer membranes with photoregulated template binding显示文摘Minoura N Idei K Rachkov A 2003Chem Mater2003,15,25:1
3Variations in tracheid length and morphological changes in tracheid tips associated with the development of compression wood 显示文摘Yoshizawa N Kiyomiya M Idei T 1987Wood Science and Technology1987,21,1:1
4Trichostatin a prevents TGF-β1 -induced apoptosis by inhibi- ting ERK activation in human renal tubular epithelial cells 显示文摘Masahiro Yoshikawa Keiichi Hishikawa Mana Idei 2010Eur J Pharmacol2010,642,3:1
5Activation of caspase 3 protease during the process of ursolic acid and its derivative induced apoptosis显示文摘Hollosy F Idei M Csorba G 2001Anticancer Research2001,21,5:1
6Three-dimensionalobservation of pulp cavites in the maxillary first premolar tooth using micro-CT 显示文摘OiT SakaH IdeY 2004Int Endod J2004,37,:1
7Influence of insulin-like growth factor-land hepatocyte growth factor on carotid atherosclerosis and cognitive function in the elderly显示文摘Watanabe T Yamamoto H Idei T 0,,01:1
8Gram - negative Baeterial ATP - binding Cassette Protein Exporter Family and Diverse Secretory Proteins显示文摘Omori K Idei A 2003J Biosei Bioeng2003,95,1:1
9Kinetic behav- ior of hydrogenation of aromatics in diesel fuel over silica- alumina-supported bimetallic Pt-Pd catalyst 显示文摘FUJIKAWA T IDEI K OHKI K 2001Applied Catalysis A : General2001,205,:1
10Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease显示文摘Yukihito Higashi Chikara Goto Takayuki Hidaka Junko Soga Shuji Nakamura Yuichi Fujii Takaki Hata Naomi Idei Noritaka Fujimura Kazuaki Chayama Yasuki Kihara Akira Taguchi 2009Atherosclerosis2009,,2:1
11Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells显示文摘Bokonyi G Idei M Sepr~li A 2000Anticancer Research2000,20,6:1
12Activation of caspase-3protease during the process of ursolic acid and its derivative-induced apoptosis显示文摘Hollosy F Idei M Csorba G 2001Anticancer Res2001,21,5:1
13A case of advanced ovarian carcinosarcoma that responded remarkably to neoadjuvant chemotherapy of combined CPT-11 and CDDP显示文摘 Idei T Nakayama Y 2002Gan To Kagaku Ryoho2002,29,2:1
14Vascular function and circulating progenitor ceils in thromboangitis obliterans(Buerger's disease)and atherosclerosis obliterans显示文摘Idei N Nishioka K Soga J 0,,01:1
15Activity of caspase-3 protease during the process of ursolic acid and its derivative-induced apoptosis 显示文摘Hollosy F Idei M Csorba G 2001Anticancer Res2001,21,5:1
16Real time polarization monitor developed for high power electron cyclotron resonance heating and current drive experiments in large helical device 显示文摘Notake T Idei H Kubo S 2005Review of Scientific Instruments2005,76,2:1
17Symmetrical bilateral epidural hematoma after head injury in the mid parietooccipitat region: case report 显示文摘Idei M Shima T Nishida M 2004No Shinkei Geka2004,32,4:1
18A novel noninvasive and simple methodfor assessment of endothelial function ; enclased zone flow-mediated vasodilation(ezFMD) using an oscillation amplitude measurement 显示文摘Idei N Ukawa T Kajikawa M 2013Atherosclerosis2013,229,2:1
19A novel noninvasive and simple method forassessment of endothelial function : enclosed zone flow-mediated vasodilation(ezFMD) using an oscillation amplitude measurement 显示文摘Idei N Ukawa T Hata T 2013Atherosclerosis2013,229,:1
20Concurrent weekly nedaplatin-based radiotherapy for high risk,recurrent and advanced cervical cancer 显示文摘Idei T Sakamoto H Nakajima Y 2003Gan To Kagaku Ryoho2003,30,4:1
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