| 5 | Case of severe alcoholic hepatitis treated with granulocytapheresis显示文摘Severe alcoholic hepatitis(AH) has a high mortality,and it is associated with encephalopathy,acute renal failure,sepsis,gastrointestinal bleeding,and endotoxemia.The 28-d mortality remains poor(34%-40%),because no effective treatment has been established.Recently,corticosteroids(CS) have been considered effective for significantly improving the prognosis of those with AH,as it prevents the production of pro-inflammatory cytokines.However,CS are not always appropriate as an initial therapeutic option,such as in cases with an infection or resistance to CS.We describe a patient with severe AH complicated by a severe infection caused by the multidrug resistance bacteria(Pseudomonas aeruginosa),and was successfully treated with granulocytapheresis monotherapy without using CS.The experience of this case will provide understanding of the disease and information treating cases without using CS. | Yukari Watanabe Kenya Kamimura Tomohiro Iwasaki Hiroyuki Abe Shunsaku Takahashi Ken-ichi Mizuno Manabu Takeuchi Atsushi Eino Ichiei Narita Shuji Terai | 2016 | World Journal of Clinical Cases2016，4，11： | 1 |
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