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| 1 | Escherichia coli tetracycline efflux determinants in relation to tetracycline residues in chicken显示文摘Objective:To screen for Escherichia coli(E.coli)resistant to tetracycline,followed by identification of tet efflux genes by polymerase chain reaction(PCR).In addition,detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mass spectrometry(HPLC-MS-MS).Methods:Strains of E.coli were isolated from samples of chicken colon and screened for tetracycline resistance.Tetracycline genes conferring resistance(Tc^r)were detected by polymerase chain reaction(PCR).Most of the isolates were resistant to tetracycline(97.9%).Results:PCR analysis indicated that Tc^r E.coli R-plasmids contained tet(A),tet(B)and a combination of both efflux genes.None of the isolates contained other efflux tet genes tet(C,D,E and Y).High performance liquid chromatography-tandem quadrupole mass spectrometry(HPLC-MS-MS),a sensitive technique,was used to detect residues of chlortetracycline(CTC),oxytetracyeline(OTC),doxveycline(DC)in chicken livers and kidneys.The samples containing tetracycline residues were at 0.13-0.65pg/μL levels.Conclusions:Tetracycline and other antibiotics are commonly used in the poultry and meat production industry for prevention of microbial infections.Multiple antibiotic resistant bacteria in Oman have increased to alarming levels,threatening public health,domestic and may have adverse effect on environment. | Al-Bahry SN Al-Mashani BM Al-Ansari AS Elshafie AE Mahmoud IY | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，9： | 4 |
| 2 | Prevention of spinal cord ischaemia during descending thoracic and thoracoabdominal aortic surgery显示文摘 | Wan IY Angelini GD Bryan AJ Ryder I Underwood MJ | 2001 | Eur J Cardiothorac Surg2001，19，2： | 2 |
| 3 | Transforming growth factor-beta: biology and clinical relevance显示文摘 | Kim IY Kim MM Kim SJ | 2005 | J Biochem Mol Biol2005，38，1： | 1 |
| 4 | Alveolar type Ⅱ cell growth on a pulmonary endothelial extracellular matrix 显示文摘 | Linda Y | 1996 | Am J Physiol1996，270，14： | 1 |
| 5 | In vitro determination of drrect antimicrobial effect of calcium hydroxide显示文摘 | Estrela C Pimenta FC Ito IY | 1998 | J Endod1998，24，5： | 1 |
| 6 | Excretory-secretory products produced by paragonimus westermani differentially regulate the nitric oxide production and viability of microglial cells显示文摘 | Jin Y Lee JC Choi IY | 2006 | Int Arch Allergy Immunol2006，139，1： | 1 |
| 7 | Antimalarials increase vesicle pH in Plasmodium falciparum 显示文摘 | Krogstad DJ Schlesinger PH Gluzman IY | 1985 | J Cell Biol1985，101，6： | 1 |
| 8 | Amplitude reduction in visual event-related potentials as a function of sleep deprivation 显示文摘 | Corsi CM Arce C del Rio Portilla IY | 1999 | Sleep1999，22，1： | 1 |
| 9 | Comparative epidemiological studies on vector/reservoir animals of tsutsugamushi disease between high and low endemic areas in Korea显示文摘 | Ree HI Cho MK Lee IY | 1995 | Korean J Parasitol1995，33，1： | 1 |
| 10 | A prospective study of the risk factors associated with failure of mini-implants used for orthodontic anchorage 显示文摘 | Cheng SJ Tseng IY Lee JJ | 2004 | Int J Oral Maxillofac Im- plants2004，19，1： | 1 |
| 11 | Predictors of post-hospital employment status for psychiatric patients in Hong Kong:From perceptions of rehabilitation professionals to empirical evidence显示文摘 | Tsang H Ng B Chiu IY | 2000 | International Journal of Social Psychiatry2000，46，4： | 1 |
| 12 | Solvothermal-assisted hy- bridization between reduced graphene oxide and lithium metal oxides: A facile route to graphene-based composite materials 显示文摘 | Han SY Kim IY Jo KY | 2012 | J Phys Chem C2012，116，13： | 1 |
| 13 | Treatment of extensively drug-resistant tuberculosis in Tomsk,Russia:a retrospective cohort study显示文摘 | Keshavjee S Gelmanova IY Farmer PE | | 0，，9647： | 1 |
| 14 | Rac1 prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells显示文摘 | Jeong HG Cho HJ Chang IY | 2012 | FEBS Lett2012，518，13： | 1 |
| 15 | Bronchoscopic lung volume reduction for end-stage emphysema:report on the first 98 patients显示文摘 | Wan IY Toma TP Geddes DM | 2006 | Chest2006，129，3： | 1 |
| 16 | MicroRNAs play an embryessential role in the development of cardiac hypertrophy显示文摘 | Sayed D Hong C Chen IY | 2007 | Circ Res2007，100，3： | 1 |
| 17 | Inhibition of NF - KB DNA binding and nitric oxide induetion in human T cells and lung adenocarcinoma cells by selenite treatment 显示文摘 | Kim IY Stadtman TC | 1997 | Proc Natl Acad Sci USA1997，94，12： | 1 |
| 18 | Mechanisms of peroxynitrite-induced injury to pulmonary surfactant显示文摘 | lschiropoules H Holm BA | 1993 | Am J Physiol1993，265，61： | 1 |
| 19 | Excretory-secretory products from Paragonimus westermani increase nitric oxide production in microglia in PKC-dependent and-independent manners 显示文摘 | Jin Y Choi IY Kim C | 2009 | Neurosci Res2009，65，2： | 1 |
| 20 | Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features 显示文摘 | Tam IY Chung LP Suen WS | 2006 | Clin Cancer Res2006，12，5： | 1 |
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