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41篇 您的检索式:作者名="IMARISIO"
    题名 作者 年代 出处 被引量
1Molecular mechanisms of liver preconditioning显示文摘Ischemia/reperfusion (I/R) injury still represents an important cause of morbidity following hepatic surgery and limits the use of marginal livers in hepatic transplantation. Transient blood flow interruption followed by reperfusion protects tissues against damage induced by subsequent I/R. This process known as ischemic pre-conditioning (IP) depends upon intrinsic cytoprotective systems whose activation can inhibit the progression of irreversible tissue damage. Compared to other organs,liver IP has additional features as it reduces inflammation and promotes hepatic regeneration. Our present understanding of the molecular mechanisms involved in liver IP is still largely incomplete. Experimental studies have shown that the protective effects of liver IP are triggered by the release of adenosine and nitric oxide and the subsequent activation of signal networks involving protein kinases such as phosphatidylinositol 3-kinase,protein kinase C δ/ε and p38 MAP kinase,and transcription factors such as signal transducer and activator of transcription 3,nuclear factor-κB and hypoxia-inducible factor 1. This article offers an overview of the molecular events underlying the preconditioning effects in the liver and points to the possibility of developing pharmacological approaches aimed at activating the intrinsic protective systems in patients undergoing liver surgery.Elisa Alchera Caterina Dal Ponte Chiara Imarisio Emanuele Albano Rita Carini 2010World Journal of Gastroenterology2010,16,48:3
2PICALM modulates autophagy activity and tau accumulation显示文摘Moreau K Fleming A Imarisio S 2014Nat Commun2014,5,:1
3Fibrin tissue dhe sive reduces postoperative blood loss in total knee arthro plasty 显示文摘Sabatini L Trecci A Imarisio D 2012Orthop Traumatol2012,13,3:1
4Adenosine-dependent activa-tion of hypoxia-inducible factor-1 induces late preconditioning in livercells显示文摘Alchera E Tacchini L Imarisio C 2008Hepatology2008,48,:1
5A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin 显示文摘Sarkar S Krishna G Imarisio S 2008Hum Mol Genet2008,17,2:1
6Effects of acute and chronic ethanol administration on regional thiamin pyrophosphokinase activity of the rat brain显示文摘Rindi G Imarisio L Patrini C 1986Biochem Pharmacol1986,35,:1
7Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis显示文摘Di Cunto F Imarisio S Hirsch E 2000Neuron2000,28,1:1
8Immunological effects of multikinase inhibitors for kidney cancer:a clue for integration with cellular therapies?显示文摘Porta C Paglino C Imarisio I 2011J Cancer2011,2,:1
9Gemcitabine and oxaliplatin in the treatment of patients with immunotherapy-resistant advanced renal ceil carcinoma: final results of a single-institution Phase Ⅱ study显示文摘Porta C Zimatore M Imarisio I 2004Cancer2004,100,10:1
10Sunitinib in advanced metastatic non-clear cell renal cell earcinoma:a single institution retrospective study 显示文摘Paglino C Imarisio I Ganini C 2012Future Oneol2012,8,:1
11Fibrin tissue adhesive reduces postoperative blood loss in total knee arthroplasty显示文摘Sabatini L Trecci A Imarisio D 0,,03:1
12Fibrin tissue adhe- sive reduces postoperative blood loss in total knee arthro- plasty显示文摘Sabatini L Trecci A Imarisio D 2012J Orthop Traumatol2012,13,3:1
13Fi- brin tissue adhesive reduces postoperative blood loss in total knee arthroplasty显示文摘Sabatini L Trecci A Imarisio D 2012J Orthop Traumatol2012,13,3:1
14A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin显示文摘Sarkar S Krishna G Imarisio S 0,,02:1
15Small molecules enhance autophagy and reduce toxicity in Huntington's disease models显示文摘Sarkar S Perlstein E O Imarisio S 0,,06:1
16Cementless total hip replacement for severe developmental dysplasia of the hip: Our experience in Crowe' s group IV 显示文摘Imarisio D Trecci A Sabatini L 2013Muscu- loskelet Surg2013,97,1:1
17Adenosine dependent activation of hypoxia-inducible factor-1 induces late preconditioning in liver cells显示文摘ALCHERA E TACCHINI L IMARISIO C 0,,01:1
18Dynein muta-tions impair autophagic clearance of aggregate-prone proteins显示文摘Ravikumar B Acevedo-Arozena A Imarisio S 0,,07:1
19A rational mechanism for combination treatment of Huntington\'s disease using lithium and rapamycin显示文摘Sarkar S Krishna G Imarisio S 2008Hum Mol Genet2008,17,2:1
20Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease 显示文摘Ravikumar B Imarisio S Sarkar S 2008J Cell Sci2008,121,10:1
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